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Showing 1 to 12 of 68 entries
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[The referral of patients within secondary health services].

Nederlands tijdschrift voor geneeskunde

Molenaar JC.
PMID: 3796750
Ned Tijdschr Geneeskd. 1986 Nov 22;130(47):2114-5.

No abstract available.

In memoriam--Professor Dr G. Den Otter, 1921-1990.

The Netherlands journal of surgery

de Boer HM, Molenaar JC.
PMID: 2057092
Neth J Surg. 1991 Apr;43(2):27-8.

No abstract available.

Prediction uncertainty assessment of a systems biology model requires a sample of the full probability distribution of its parameters.

PeerJ

van Mourik S, Ter Braak C, Stigter H, Molenaar J.
PMID: 25024907
PeerJ. 2014 Jun 17;2:e433. doi: 10.7717/peerj.433. eCollection 2014.

Multi-parameter models in systems biology are typically 'sloppy': some parameters or combinations of parameters may be hard to estimate from data, whereas others are not. One might expect that parameter uncertainty automatically leads to uncertain predictions, but this is...

Predictors of false lumen thrombosis in type B aortic dissection treated with TEVAR.

Annals of cardiothoracic surgery

Tolenaar JL, Kern JA, Jonker FH, Cherry KJ, Tracci MC, Angle JF, Sabri S, Trimarchi S, Strider D, Alaiwaidi G, Upchurch GR.
PMID: 24967164
Ann Cardiothorac Surg. 2014 May;3(3):255-63. doi: 10.3978/j.issn.2225-319X.2014.05.17.

BACKGROUND: Thoracic endovascular aortic repair (TEVAR) offers a less invasive treatment option in type B aortic dissection (TBAD) patients and its value has been demonstrated in acute and chronic dissection patients. Total false lumen thrombosis (FLT) is associated with...

Parameter estimation in tree graph metabolic networks.

PeerJ

Astola L, Stigter H, Gomez Roldan MV, van Eeuwijk F, Hall RD, Groenenboom M, Molenaar JJ.
PMID: 27688960
PeerJ. 2016 Sep 20;4:e2417. doi: 10.7717/peerj.2417. eCollection 2016.

We study the glycosylation processes that convert initially toxic substrates to nutritionally valuable metabolites in the flavonoid biosynthesis pathway of tomato (Solanum lycopersicum) seedlings. To estimate the reaction rates we use ordinary differential equations (ODEs) to model the enzyme...

Floral pathway integrator gene expression mediates gradual transmission of environmental and endogenous cues to flowering time.

PeerJ

van Dijk ADJ, Molenaar J.
PMID: 28439467
PeerJ. 2017 Apr 19;5:e3197. doi: 10.7717/peerj.3197. eCollection 2017.

The appropriate timing of flowering is crucial for the reproductive success of plants. Hence, intricate genetic networks integrate various environmental and endogenous cues such as temperature or hormonal statues. These signals integrate into a network of floral pathway integrator...

A molecular model for cohesive slip at polymer melt/solid interfaces.

The Journal of chemical physics

Tchesnokov MA, Molenaar J, Slot JJ, Stepanyan R.
PMID: 15974766
J Chem Phys. 2005 Jun 01;122(21):214711. doi: 10.1063/1.1915327.

A molecular model is proposed which predicts wall slip by disentanglement of polymer chains adsorbed on a wall from those in the polymer bulk. The dynamics of the near-wall boundary layer is found to be governed by a nonlinear...

Erratum to: more complications in uncemented compared to cemented hemiarthroplasty for displaced femoral neck fractures: a randomized controlled trial of 201 patients, with one year follow-up.

BMC musculoskeletal disorders

Moerman S, Mathijssen NMC, Niesten DD, Riedijk R, Rijnberg WJ, Koëter S, van de Hei KK, Tuinebreijer WE, Molenaar TL, Nelissen RGHH, Vochteloo AJH.
PMID: 28716066
BMC Musculoskelet Disord. 2017 Jul 17;18(1):300. doi: 10.1186/s12891-017-1661-7.

No abstract available.

Network inference via adaptive optimal design.

BMC research notes

Stigter JD, Molenaar J.
PMID: 22999252
BMC Res Notes. 2012 Sep 24;5:518. doi: 10.1186/1756-0500-5-518.

BACKGROUND: Current research in network reverse engineering for genetic or metabolic networks very often does not include a proper experimental and/or input design. In this paper we address this issue in more detail and suggest a method that includes...

Author Correction: The landscape of genomic alterations across childhood cancers.

Nature

Gröbner SN, Worst BC, Weischenfeldt J, Buchhalter I, Kleinheinz K, Rudneva VA, Johann PD, Balasubramanian GP, Segura-Wang M, Brabetz S, Bender S, Hutter B, Sturm D, Pfaff E, Hübschmann D, Zipprich G, Heinold M, Eils J, Lawerenz C, Erkek S, Lambo S, Waszak S, Blattmann C, Borkhardt A, Kuhlen M, Eggert A, Fulda S, Gessler M, Wegert J, Kappler R, Baumhoer D, Burdach S, Kirschner-Schwabe R, Kontny U, Kulozik AE, Lohmann D, Hettmer S, Eckert C, Bielack S, Nathrath M, Niemeyer C, Richter GH, Schulte J, Siebert R, Westermann F, Molenaar JJ, Vassal G, Witt H, Burkhardt B, Kratz CP, Witt O, van Tilburg CM, Kramm CM, Fleischhack G, Dirksen U, Rutkowski S, Frühwald M, von Hoff K, Wolf S, Klingebiel T, Koscielniak E, Landgraf P, Koster J, Resnick AC, Zhang J, Liu Y, Zhou X, Waanders AJ, Zwijnenburg DA, Raman P, Brors B, Weber UD, Northcott PA, Pajtler KW, Kool M, Piro RM, Korbel JO, Schlesner M, Eils R, Jones DTW, Lichter P, Chavez L, Zapatka M, Pfister SM.
PMID: 29875405
Nature. 2018 Jul;559(7714):E10. doi: 10.1038/s41586-018-0167-2.

In this Article, author Benedikt Brors was erroneously associated with affiliation number '8' (Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, Tennessee, USA); the author's two other affiliations (affiliations '3' and '7', both at the German Cancer...

Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies.

European journal of cancer (Oxford, England : 1990)

Keller KM, Krausert S, Gopisetty A, Luedtke D, Koster J, Schubert NA, Rodríguez A, van Hooff SR, Stichel D, Dolman MEM, Vassal G, Pfister SM, Caron HN, Stancato LF, Molenaar JJ, Jäger N, Kool M.
PMID: 34963094
Eur J Cancer. 2021 Dec 25;162:107-117. doi: 10.1016/j.ejca.2021.11.030. Epub 2021 Dec 25.

BACKGROUND: Owing to the high numbers of paediatric cancer-related deaths, advances in therapeutic options for childhood cancer is a heavily studied field, especially over the past decade. Classical chemotherapy offers some therapeutic benefit but has proven long-term complications in...

Refractory Stage M Ganglioneuroblastoma With Bone Metastases and a Favorable, Chronic Course of Disease: Description of a Patient Cohort.

Journal of pediatric hematology/oncology

Tas ML, Molenaar JJ, Peek AML, Lequin MH, Verdijk RM, de Krijger RR, Tytgat GAM, van Noesel MM.
PMID: 33885033
J Pediatr Hematol Oncol. 2022 Jan 01;44(1):e5-e13. doi: 10.1097/MPH.0000000000002067.

Refractory stage M neuroblastoma (NB) is associated with a poor prognosis and a progressive course of disease. Here, we describe a unique group of patients with a discrepant clinical course. Seven histologically confirmed ganglioneuroblastoma (GNB) (n=6) and differentiating NB...

Showing 1 to 12 of 68 entries