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Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.

JAMA neurology

Kia DA, Zhang D, Guelfi S, Manzoni C, Hubbard L, Reynolds RH, Botía J, Ryten M, Ferrari R, Lewis PA, Williams N, Trabzuni D, Hardy J, Wood NW.
PMID: 33523105
JAMA Neurol. 2021 Apr 01;78(4):464-472. doi: 10.1001/jamaneurol.2020.5257.

IMPORTANCE: Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated with increased risk of disease. Improved understanding of the underlying genes and...

Cite
Kia DA, Zhang D, Guelfi S, et al. Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA Neurol. 2021;78(4):464-472doi: 10.1001/jamaneurol.2020.5257.
Kia, D. A., Zhang, D., Guelfi, S., Manzoni, C., Hubbard, L., Reynolds, R. H., Botía, J., Ryten, M., Ferrari, R., Lewis, P. A., Williams, N., Trabzuni, D., Hardy, J., Wood, N. W. (2021). Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA neurology, 78(4), 464-472. https://doi.org/10.1001/jamaneurol.2020.5257
Kia, Demis A, et al. "Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets." JAMA neurology vol. 78,4 (2021): 464-472. doi: https://doi.org/10.1001/jamaneurol.2020.5257
Kia DA, Zhang D, Guelfi S, Manzoni C, Hubbard L, Reynolds RH, Botía J, Ryten M, Ferrari R, Lewis PA, Williams N, Trabzuni D, Hardy J, Wood NW. Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA Neurol. 2021 Apr 01;78(4):464-472. doi: 10.1001/jamaneurol.2020.5257. PMID: 33523105; PMCID: PMC7851759.
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Author Correction: Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset.

Scientific reports

Sng LMF, Thomson PC, Trabzuni D.
PMID: 32999326
Sci Rep. 2020 Oct 01;10(1):16603. doi: 10.1038/s41598-020-73067-3.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Sng LMF, Thomson PC, Trabzuni D. Author Correction: Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset. Sci Rep. 2020;10(1):16603doi: 10.1038/s41598-020-73067-3.
Sng, L. M. F., Thomson, P. C., & Trabzuni, D. (2020). Author Correction: Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset. Scientific reports, 10(1), 16603. https://doi.org/10.1038/s41598-020-73067-3
Sng, Letitia M F, et al. "Author Correction: Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset." Scientific reports vol. 10,1 (2020): 16603. doi: https://doi.org/10.1038/s41598-020-73067-3
Sng LMF, Thomson PC, Trabzuni D. Author Correction: Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset. Sci Rep. 2020 Oct 01;10(1):16603. doi: 10.1038/s41598-020-73067-3. PMID: 32999326; PMCID: PMC7527956.
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Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.

JAMA neurology

Kia DA, Zhang D, Guelfi S, Manzoni C, Hubbard L, Reynolds RH, Botía J, Ryten M, Ferrari R, Lewis PA, Williams N, Trabzuni D, Hardy J, Wood NW.
PMID: 33523105
JAMA Neurol. 2021 Apr 01;78(4):464-472. doi: 10.1001/jamaneurol.2020.5257.

IMPORTANCE: Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated with increased risk of disease. Improved understanding of the underlying genes and...

Cite
Kia DA, Zhang D, Guelfi S, et al. Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA Neurol. 2021;78(4):464-472doi: 10.1001/jamaneurol.2020.5257.
Kia, D. A., Zhang, D., Guelfi, S., Manzoni, C., Hubbard, L., Reynolds, R. H., Botía, J., Ryten, M., Ferrari, R., Lewis, P. A., Williams, N., Trabzuni, D., Hardy, J., Wood, N. W. (2021). Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA neurology, 78(4), 464-472. https://doi.org/10.1001/jamaneurol.2020.5257
Kia, Demis A, et al. "Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets." JAMA neurology vol. 78,4 (2021): 464-472. doi: https://doi.org/10.1001/jamaneurol.2020.5257
Kia DA, Zhang D, Guelfi S, Manzoni C, Hubbard L, Reynolds RH, Botía J, Ryten M, Ferrari R, Lewis PA, Williams N, Trabzuni D, Hardy J, Wood NW. Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA Neurol. 2021 Apr 01;78(4):464-472. doi: 10.1001/jamaneurol.2020.5257. PMID: 33523105; PMCID: PMC7851759.
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Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12].

Neurobiology of aging

Ferrari R, Ryten M, Simone R, Trabzuni D, Nicolaou N, Hondhamuni G, Ramasamy A, Vandrovcova J, Weale ME, Lees AJ, Momeni P, Hardy J, de Silva R.
PMID: 28764847
Neurobiol Aging. 2015 Nov;36(11):3118. doi: 10.1016/j.neurobiolaging.2015.10.005. Epub 2015 Oct 19.

No abstract available.

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Ferrari R, Ryten M, Simone R, et al. Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12]. Neurobiol Aging. 2015;36(11):3118doi: 10.1016/j.neurobiolaging.2015.10.005.
Ferrari, R., Ryten, M., Simone, R., Trabzuni, D., Nicolaou, N., Hondhamuni, G., Ramasamy, A., Vandrovcova, J., Weale, M. E., Lees, A. J., Momeni, P., Hardy, J., & de Silva, R. (2015). Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12]. Neurobiology of aging, 36(11), 3118. https://doi.org/10.1016/j.neurobiolaging.2015.10.005
Ferrari, Raffaele, et al. "Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12]." Neurobiology of aging vol. 36,11 (2015): 3118. doi: https://doi.org/10.1016/j.neurobiolaging.2015.10.005
Ferrari R, Ryten M, Simone R, Trabzuni D, Nicolaou N, Hondhamuni G, Ramasamy A, Vandrovcova J, Weale ME, Lees AJ, Momeni P, Hardy J, de Silva R. Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12]. Neurobiol Aging. 2015 Nov;36(11):3118. doi: 10.1016/j.neurobiolaging.2015.10.005. Epub 2015 Oct 19. PMID: 28764847; PMCID: PMC5603716.
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Comparison Between Expression Microarrays and RNA-Sequencing Using UKBEC Dataset Identified a .

Frontiers in neurology and neuroscience research

Sng LMF, Thomson PC, Trabzuni D.
PMID: 34322689
Front Neurol Neurosci Res. 2020 Sep 16;1:100001. eCollection 2020 Sep 16.

In recent years, the advantages of RNA-sequencing (RNA-Seq) have made it the platform of choice for measuring gene expression over traditional microarrays. However, RNA-Seq comes with bioinformatical challenges and higher computational costs. Therefore, this study set out to assess...

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Sng LMF, Thomson PC, Trabzuni D. Comparison Between Expression Microarrays and RNA-Sequencing Using UKBEC Dataset Identified a . Front Neurol Neurosci Res. 2020;1:100001
Sng, L. M. F., Thomson, P. C., & Trabzuni, D. (2020). Comparison Between Expression Microarrays and RNA-Sequencing Using UKBEC Dataset Identified a . Frontiers in neurology and neuroscience research, 1100001.
Sng, Letitia M F, et al. "Comparison Between Expression Microarrays and RNA-Sequencing Using UKBEC Dataset Identified a ." Frontiers in neurology and neuroscience research vol. 1 (2020): 100001.
Sng LMF, Thomson PC, Trabzuni D. Comparison Between Expression Microarrays and RNA-Sequencing Using UKBEC Dataset Identified a . Front Neurol Neurosci Res. 2020 Sep 16;1:100001. eCollection 2020 Sep 16. PMID: 34322689; PMCID: PMC7611373.
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Novel mutations underlying argininosuccinic aciduria in Saudi Arabia.

BMC research notes

Imtiaz F, Al-Sayed M, Trabzuni D, Al-Mubarak BR, Alsmadi O, Rashed MS, Meyer BF.
PMID: 20298553
BMC Res Notes. 2010 Mar 18;3:79. doi: 10.1186/1756-0500-3-79.

BACKGROUND: Argininosuccinic aciduria (ASAuria) is an autosomal recessive disorder of the urea cycle relatively common in Saudi Arabia as a consequence of extensive consanguinity. It is the most common urea cycle disorder identified in the Saudi population, which therefore...

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Imtiaz F, Al-Sayed M, Trabzuni D, et al. Novel mutations underlying argininosuccinic aciduria in Saudi Arabia. BMC Res Notes. 2010;3:79doi: 10.1186/1756-0500-3-79.
Imtiaz, F., Al-Sayed, M., Trabzuni, D., Al-Mubarak, B. R., Alsmadi, O., Rashed, M. S., & Meyer, B. F. (2010). Novel mutations underlying argininosuccinic aciduria in Saudi Arabia. BMC research notes, 379. https://doi.org/10.1186/1756-0500-3-79
Imtiaz, Faiqa, et al. "Novel mutations underlying argininosuccinic aciduria in Saudi Arabia." BMC research notes vol. 3 (2010): 79. doi: https://doi.org/10.1186/1756-0500-3-79
Imtiaz F, Al-Sayed M, Trabzuni D, Al-Mubarak BR, Alsmadi O, Rashed MS, Meyer BF. Novel mutations underlying argininosuccinic aciduria in Saudi Arabia. BMC Res Notes. 2010 Mar 18;3:79. doi: 10.1186/1756-0500-3-79. PMID: 20298553; PMCID: PMC2851718.
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Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset.

Scientific reports

Sng LMF, Thomson PC, Trabzuni D.
PMID: 31844111
Sci Rep. 2019 Dec 16;9(1):19201. doi: 10.1038/s41598-019-55590-0.

Understanding the complexity of the human brain transcriptome architecture is one of the most important human genetics study areas. Previous studies have applied expression quantitative trait loci (eQTL) analysis at the genome-wide level of the brain to understand the...

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Sng LMF, Thomson PC, Trabzuni D. Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset. Sci Rep. 2019;9(1):19201doi: 10.1038/s41598-019-55590-0.
Sng, L. M. F., Thomson, P. C., & Trabzuni, D. (2019). Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset. Scientific reports, 9(1), 19201. https://doi.org/10.1038/s41598-019-55590-0
Sng, Letitia M F, et al. "Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset." Scientific reports vol. 9,1 (2019): 19201. doi: https://doi.org/10.1038/s41598-019-55590-0
Sng LMF, Thomson PC, Trabzuni D. Genome-wide human brain eQTLs: In-depth analysis and insights using the UKBEC dataset. Sci Rep. 2019 Dec 16;9(1):19201. doi: 10.1038/s41598-019-55590-0. PMID: 31844111; PMCID: PMC6915738.
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Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke.

European stroke journal

Paciaroni M, Angelini F, Agnelli G, Tsivgoulis G, Furie KL, Tadi P, Becattini C, Falocci N, Zedde M, Abdul-Rahim AH, Lees KR, Alberti A, Venti M, Acciarresi M, Altavilla R, D'Amore C, Mosconi MG, Cimini LA, Bovi P, Carletti M, Rigatelli A, Cappellari M, Putaala J, Tomppo L, Tatlisumak T, Bandini F, Marcheselli S, Pezzini A, Poli L, Padovani A, Masotti L, Vannucchi V, Sohn SI, Lorenzini G, Tassi R, Guideri F, Acampa M, Martini G, Ntaios G, Karagkiozi E, Athanasakis G, Makaritsis K, Vadikolias K, Liantinioti C, Chondrogianni M, Mumoli N, Consoli D, Galati F, Sacco S, Carolei A, Tiseo C, Corea F, Ageno W, Bellesini M, Silvestrelli G, Ciccone A, Scoditti U, Denti L, Mancuso M, Maccarrone M, Orlandi G, Giannini N, Gialdini G, Tassinari T, Lodovici ML, Bono G, Rueckert C, Baldi A, Toni D, Letteri F, Giuntini M, Lotti EM, Flomin Y, Pieroni A, Kargiotis O, Karapanayiotides T, Monaco S, Baronello MM, Csiba L, Szabó L, Chiti A, Giorli E, Sette MD, Imberti D, Zabzuni D, Doronin B, Volodina V, Michel Pd-Mer P, Vanacker P, Barlinn K, Pallesen LP, Kepplinger J, Deleu D, Melikyan G, Ibrahim F, Akhtar N, Gourbali V, Yaghi S, Caso V.
PMID: 31165095
Eur Stroke J. 2019 Mar;4(1):55-64. doi: 10.1177/2396987318785853. Epub 2018 Jul 25.

BACKGROUND: The relationship between different patterns of atrial fibrillation and early recurrence after an acute ischaemic stroke is unclear.PURPOSE: In a prospective cohort study, we evaluated the rates of early ischaemic recurrence after an acute ischaemic stroke in patients...

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Paciaroni M, Angelini F, Agnelli G, et al. Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke. Eur Stroke J. 2018;4(1):55-64doi: 10.1177/2396987318785853.
Paciaroni, M., Angelini, F., Agnelli, G., Tsivgoulis, G., Furie, K. L., Tadi, P., Becattini, C., Falocci, N., Zedde, M., Abdul-Rahim, A. H., Lees, K. R., Alberti, A., Venti, M., Acciarresi, M., Altavilla, R., D'Amore, C., Mosconi, M. G., Cimini, L. A., Bovi, P., Carletti, M., Rigatelli, A., Cappellari, M., Putaala, J., Tomppo, L., Tatlisumak, T., Bandini, F., Marcheselli, S., Pezzini, A., Poli, L., Padovani, A., Masotti, L., Vannucchi, V., Sohn, S. I., Lorenzini, G., Tassi, R., Guideri, F., Acampa, M., Martini, G., Ntaios, G., Karagkiozi, E., Athanasakis, G., Makaritsis, K., Vadikolias, K., Liantinioti, C., Chondrogianni, M., Mumoli, N., Consoli, D., Galati, F., Sacco, S., Carolei, A., Tiseo, C., Corea, F., Ageno, W., Bellesini, M., Silvestrelli, G., Ciccone, A., Scoditti, U., Denti, L., Mancuso, M., Maccarrone, M., Orlandi, G., Giannini, N., Gialdini, G., Tassinari, T., Lodovici, M. L., Bono, G., Rueckert, C., Baldi, A., Toni, D., Letteri, F., Giuntini, M., Lotti, E. M., Flomin, Y., Pieroni, A., Kargiotis, O., Karapanayiotides, T., Monaco, S., Baronello, M. M., Csiba, L., Szabó, L., Chiti, A., Giorli, E., Sette, M. D., Imberti, D., Zabzuni, D., Doronin, B., Volodina, V., Michel Pd-Mer, P., Vanacker, P., Barlinn, K., Pallesen, L. P., Kepplinger, J., Deleu, D., Melikyan, G., Ibrahim, F., Akhtar, N., Gourbali, V., Yaghi, S., & Caso, V. (2019). Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke. European stroke journal, 4(1), 55-64. https://doi.org/10.1177/2396987318785853
Paciaroni, Maurizio, et al. "Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke." European stroke journal vol. 4,1 (2019): 55-64. doi: https://doi.org/10.1177/2396987318785853
Paciaroni M, Angelini F, Agnelli G, Tsivgoulis G, Furie KL, Tadi P, Becattini C, Falocci N, Zedde M, Abdul-Rahim AH, Lees KR, Alberti A, Venti M, Acciarresi M, Altavilla R, D'Amore C, Mosconi MG, Cimini LA, Bovi P, Carletti M, Rigatelli A, Cappellari M, Putaala J, Tomppo L, Tatlisumak T, Bandini F, Marcheselli S, Pezzini A, Poli L, Padovani A, Masotti L, Vannucchi V, Sohn SI, Lorenzini G, Tassi R, Guideri F, Acampa M, Martini G, Ntaios G, Karagkiozi E, Athanasakis G, Makaritsis K, Vadikolias K, Liantinioti C, Chondrogianni M, Mumoli N, Consoli D, Galati F, Sacco S, Carolei A, Tiseo C, Corea F, Ageno W, Bellesini M, Silvestrelli G, Ciccone A, Scoditti U, Denti L, Mancuso M, Maccarrone M, Orlandi G, Giannini N, Gialdini G, Tassinari T, Lodovici ML, Bono G, Rueckert C, Baldi A, Toni D, Letteri F, Giuntini M, Lotti EM, Flomin Y, Pieroni A, Kargiotis O, Karapanayiotides T, Monaco S, Baronello MM, Csiba L, Szabó L, Chiti A, Giorli E, Sette MD, Imberti D, Zabzuni D, Doronin B, Volodina V, Michel Pd-Mer P, Vanacker P, Barlinn K, Pallesen LP, Kepplinger J, Deleu D, Melikyan G, Ibrahim F, Akhtar N, Gourbali V, Yaghi S, Caso V. Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke. Eur Stroke J. 2019 Mar;4(1):55-64. doi: 10.1177/2396987318785853. Epub 2018 Jul 25. PMID: 31165095; PMCID: PMC6533867.
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Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes.

European stroke journal

Paciaroni M, Agnelli G, Giustozzi M, Tsivgoulis G, Yaghi S, Grory BM, Furie KL, Tadi P, Zedde M, Abdul-Rahim AH, Dawson J, Lees KR, Alberti A, Venti M, Acciarresi M, D'Amore C, Mosconi MG, Bogini V, Cappellari M, Rigatelli A, Bonetti B, Putaala J, Tomppo L, Tatlisumak T, Bandini F, Marcheselli S, Pezzini A, Poli L, Padovani A, Masotti L, Grifoni E, Vannucchi V, Sohn SI, Lorenzini G, Tassi R, Guideri F, Acampa M, Martini G, Ntaios G, Athanasakis G, Makaritsis K, Karagkiozi E, Vadikolias K, Liantinioti C, Palaiodimou L, Mumoli N, Porta C, Galati F, Sacco S, Tiseo C, Corea F, Ageno W, Bellesini M, Silvestrelli G, Ciccone A, Scoditti U, Denti L, Mancuso M, Caselli MC, Maccarrone M, Ulivi L, Orlandi G, Giannini N, Tassinari T, Lodovici ML, Rueckert C, Baldi A, Toni D, Gentile L, Letteri F, Giuntini M, Lotti EM, Flomin Y, Pieroni A, Kargiotis O, Karapanayiotides T, Monaco S, Mannino M, Baronello MM, Csiba L, Szabó L, Chiti A, Giorli E, Sette MD, Schirinzi E, Imberti D, Zabzuni D, Doronin B, Volodina V, Michel P, Eskandari A, Vanacker P, Barlinn K, Barlinn J, Deleu D, Gourbali V, Caso V.
PMID: 33598556
Eur Stroke J. 2020 Dec;5(4):374-383. doi: 10.1177/2396987320937116. Epub 2020 Jul 22.

INTRODUCTION: The aim of this study in patients with acute posterior ischaemic stroke (PS) and atrial fibrillation (AF) was to evaluate (1) the risks of recurrent ischaemic event and severe bleeding and (2) these risks in relation with oral...

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Paciaroni M, Agnelli G, Giustozzi M, et al. Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes. Eur Stroke J. 2020;5(4):374-383doi: 10.1177/2396987320937116.
Paciaroni, M., Agnelli, G., Giustozzi, M., Tsivgoulis, G., Yaghi, S., Grory, B. M., Furie, K. L., Tadi, P., Zedde, M., Abdul-Rahim, A. H., Dawson, J., Lees, K. R., Alberti, A., Venti, M., Acciarresi, M., D'Amore, C., Mosconi, M. G., Bogini, V., Cappellari, M., Rigatelli, A., Bonetti, B., Putaala, J., Tomppo, L., Tatlisumak, T., Bandini, F., Marcheselli, S., Pezzini, A., Poli, L., Padovani, A., Masotti, L., Grifoni, E., Vannucchi, V., Sohn, S. I., Lorenzini, G., Tassi, R., Guideri, F., Acampa, M., Martini, G., Ntaios, G., Athanasakis, G., Makaritsis, K., Karagkiozi, E., Vadikolias, K., Liantinioti, C., Palaiodimou, L., Mumoli, N., Porta, C., Galati, F., Sacco, S., Tiseo, C., Corea, F., Ageno, W., Bellesini, M., Silvestrelli, G., Ciccone, A., Scoditti, U., Denti, L., Mancuso, M., Caselli, M. C., Maccarrone, M., Ulivi, L., Orlandi, G., Giannini, N., Tassinari, T., Lodovici, M. L., Rueckert, C., Baldi, A., Toni, D., Gentile, L., Letteri, F., Giuntini, M., Lotti, E. M., Flomin, Y., Pieroni, A., Kargiotis, O., Karapanayiotides, T., Monaco, S., Mannino, M., Baronello, M. M., Csiba, L., Szabó, L., Chiti, A., Giorli, E., Sette, M. D., Schirinzi, E., Imberti, D., Zabzuni, D., Doronin, B., Volodina, V., Michel, P., Eskandari, A., Vanacker, P., Barlinn, K., Barlinn, J., Deleu, D., Gourbali, V., & Caso, V. (2020). Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes. European stroke journal, 5(4), 374-383. https://doi.org/10.1177/2396987320937116
Paciaroni, Maurizio, et al. "Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes." European stroke journal vol. 5,4 (2020): 374-383. doi: https://doi.org/10.1177/2396987320937116
Paciaroni M, Agnelli G, Giustozzi M, Tsivgoulis G, Yaghi S, Grory BM, Furie KL, Tadi P, Zedde M, Abdul-Rahim AH, Dawson J, Lees KR, Alberti A, Venti M, Acciarresi M, D'Amore C, Mosconi MG, Bogini V, Cappellari M, Rigatelli A, Bonetti B, Putaala J, Tomppo L, Tatlisumak T, Bandini F, Marcheselli S, Pezzini A, Poli L, Padovani A, Masotti L, Grifoni E, Vannucchi V, Sohn SI, Lorenzini G, Tassi R, Guideri F, Acampa M, Martini G, Ntaios G, Athanasakis G, Makaritsis K, Karagkiozi E, Vadikolias K, Liantinioti C, Palaiodimou L, Mumoli N, Porta C, Galati F, Sacco S, Tiseo C, Corea F, Ageno W, Bellesini M, Silvestrelli G, Ciccone A, Scoditti U, Denti L, Mancuso M, Caselli MC, Maccarrone M, Ulivi L, Orlandi G, Giannini N, Tassinari T, Lodovici ML, Rueckert C, Baldi A, Toni D, Gentile L, Letteri F, Giuntini M, Lotti EM, Flomin Y, Pieroni A, Kargiotis O, Karapanayiotides T, Monaco S, Mannino M, Baronello MM, Csiba L, Szabó L, Chiti A, Giorli E, Sette MD, Schirinzi E, Imberti D, Zabzuni D, Doronin B, Volodina V, Michel P, Eskandari A, Vanacker P, Barlinn K, Barlinn J, Deleu D, Gourbali V, Caso V. Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes. Eur Stroke J. 2020 Dec;5(4):374-383. doi: 10.1177/2396987320937116. Epub 2020 Jul 22. PMID: 33598556; PMCID: PMC7856592.
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Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme .

Multiple sclerosis and related disorders

Ramasamy A, Trabzuni D, Forabosco P, Smith C, Walker R, Dillman A, Sveinbjornsdottir S, Hardy J, Weale ME, Ryten M.
PMID: 25568836
Mult Scler Relat Disord. 2014 Mar;3(2):211-219. doi: 10.1016/j.msard.2013.08.009.

BACKGROUND: Multiple sclerosis (MS) is a common disease of the central nervous system and a major cause of disability amongst young adults. Genome-wide association studies have identified many novel susceptibility loci including rs2248359. We hypothesized that genotypes of this...

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Ramasamy A, Trabzuni D, Forabosco P, et al. Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme . Mult Scler Relat Disord. 2014;3(2):211-219doi: 10.1016/j.msard.2013.08.009.
Ramasamy, A., Trabzuni, D., Forabosco, P., Smith, C., Walker, R., Dillman, A., Sveinbjornsdottir, S., Hardy, J., Weale, M. E., & Ryten, M. (2014). Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme . Multiple sclerosis and related disorders, 3(2), 211-219. https://doi.org/10.1016/j.msard.2013.08.009
Ramasamy, Adaikalavan, et al. "Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme ." Multiple sclerosis and related disorders vol. 3,2 (2014): 211-219. doi: https://doi.org/10.1016/j.msard.2013.08.009
Ramasamy A, Trabzuni D, Forabosco P, Smith C, Walker R, Dillman A, Sveinbjornsdottir S, Hardy J, Weale ME, Ryten M. Genetic evidence for a pathogenic role for the vitamin D3 metabolizing enzyme . Mult Scler Relat Disord. 2014 Mar;3(2):211-219. doi: 10.1016/j.msard.2013.08.009. PMID: 25568836; PMCID: PMC4278441.
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Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation).

European stroke journal

Antonenko K, Paciaroni M, Agnelli G, Falocci N, Becattini C, Marcheselli S, Rueckert C, Pezzini A, Poli L, Padovani A, Csiba L, Szabó L, Sohn SI, Tassinari T, Abdul-Rahim AH, Michel P, Cordier M, Vanacker P, Remillard S, Alberti A, Venti M, Acciarresi M, D'Amore C, Scoditti U, Denti L, Orlandi G, Chiti A, Gialdini G, Bovi P, Carletti M, Rigatelli A, Putaala J, Tatlisumak T, Masotti L, Lorenzini G, Tassi R, Guideri F, Martini G, Tsivgoulis G, Vadikolias K, Papageorgiou SG, Corea F, Sette MD, Ageno W, Lodovici ML, Bono G, Baldi A, D'Anna S, Sacco S, Carolei A, Tiseo C, Imberti D, Zabzuni D, Doronin B, Volodina V, Consoli D, Galati F, Pieroni A, Toni D, Monaco S, Baronello MM, Barlinn K, Pallesen LP, Kepplinger J, Bodechtel U, Gerber J, Deleu D, Melikyan G, Ibrahim F, Akhtar N, Mosconi MG, Lees KR, Caso V.
PMID: 30886901
Eur Stroke J. 2017 Mar;2(1):46-53. doi: 10.1177/2396987316679577. Epub 2016 Nov 15.

INTRODUCTION: Atrial fibrillation is an independent risk factor of thromboembolism. Women with atrial fibrillation are at a higher overall risk for stroke compared to men with atrial fibrillation. The aim of this study was to evaluate for sex differences...

Cite
Antonenko K, Paciaroni M, Agnelli G, et al. Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation). Eur Stroke J. 2016;2(1):46-53doi: 10.1177/2396987316679577.
Antonenko, K., Paciaroni, M., Agnelli, G., Falocci, N., Becattini, C., Marcheselli, S., Rueckert, C., Pezzini, A., Poli, L., Padovani, A., Csiba, L., Szabó, L., Sohn, S. I., Tassinari, T., Abdul-Rahim, A. H., Michel, P., Cordier, M., Vanacker, P., Remillard, S., Alberti, A., Venti, M., Acciarresi, M., D'Amore, C., Scoditti, U., Denti, L., Orlandi, G., Chiti, A., Gialdini, G., Bovi, P., Carletti, M., Rigatelli, A., Putaala, J., Tatlisumak, T., Masotti, L., Lorenzini, G., Tassi, R., Guideri, F., Martini, G., Tsivgoulis, G., Vadikolias, K., Papageorgiou, S. G., Corea, F., Sette, M. D., Ageno, W., Lodovici, M. L., Bono, G., Baldi, A., D'Anna, S., Sacco, S., Carolei, A., Tiseo, C., Imberti, D., Zabzuni, D., Doronin, B., Volodina, V., Consoli, D., Galati, F., Pieroni, A., Toni, D., Monaco, S., Baronello, M. M., Barlinn, K., Pallesen, L. P., Kepplinger, J., Bodechtel, U., Gerber, J., Deleu, D., Melikyan, G., Ibrahim, F., Akhtar, N., Mosconi, M. G., Lees, K. R., & Caso, V. (2017). Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation). European stroke journal, 2(1), 46-53. https://doi.org/10.1177/2396987316679577
Antonenko, Kateryna, et al. "Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation)." European stroke journal vol. 2,1 (2017): 46-53. doi: https://doi.org/10.1177/2396987316679577
Antonenko K, Paciaroni M, Agnelli G, Falocci N, Becattini C, Marcheselli S, Rueckert C, Pezzini A, Poli L, Padovani A, Csiba L, Szabó L, Sohn SI, Tassinari T, Abdul-Rahim AH, Michel P, Cordier M, Vanacker P, Remillard S, Alberti A, Venti M, Acciarresi M, D'Amore C, Scoditti U, Denti L, Orlandi G, Chiti A, Gialdini G, Bovi P, Carletti M, Rigatelli A, Putaala J, Tatlisumak T, Masotti L, Lorenzini G, Tassi R, Guideri F, Martini G, Tsivgoulis G, Vadikolias K, Papageorgiou SG, Corea F, Sette MD, Ageno W, Lodovici ML, Bono G, Baldi A, D'Anna S, Sacco S, Carolei A, Tiseo C, Imberti D, Zabzuni D, Doronin B, Volodina V, Consoli D, Galati F, Pieroni A, Toni D, Monaco S, Baronello MM, Barlinn K, Pallesen LP, Kepplinger J, Bodechtel U, Gerber J, Deleu D, Melikyan G, Ibrahim F, Akhtar N, Mosconi MG, Lees KR, Caso V. Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation). Eur Stroke J. 2017 Mar;2(1):46-53. doi: 10.1177/2396987316679577. Epub 2016 Nov 15. PMID: 30886901; PMCID: PMC6377059.
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