Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 21 entries
Sorted by: Best Match Show Resources per page
Peripheral and Intestinal T-regulatory Cells are Upregulated in Children with Inflammatory Bowel Disease at Onset of Disease.

Immunological investigations

Sznurkowska K, Żawrocki A, Sznurkowski J, Zieliński M, Landowski P, Plata-Nazar K, Iżycka-Świeszewska E, Trzonkowski P, Szlagatys-Sidorkiewicz A, Kamińska B.
PMID: 27759462
Immunol Invest. 2016 Nov;45(8):787-796. doi: 10.1080/08820139.2016.1214961. Epub 2016 Oct 19.

BACKGROUND/AIMS: To determine the proportion of T-regulatory cells (CD4MATERIAL AND METHODS: 24 patients newly diagnosed for IBD were included in the study: ulcerative colitis (UC; n = 13) and Crohn's disease (CD; n = 11). Seventeen healthy controls (HC)...

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part II: The Treg role in skin diseases pathogenesis.

Postepy dermatologii i alergologii

Nedoszytko B, Lange M, Sokołowska-Wojdyło M, Renke J, Trzonkowski P, Sobjanek M, Szczerkowska-Dobosz A, Niedoszytko M, Górska A, Romantowski J, Czarny J, Skokowski J, Kalinowski L, Nowicki R.
PMID: 29507554
Postepy Dermatol Alergol. 2017 Oct;34(5):405-417. doi: 10.5114/ada.2017.71105. Epub 2017 Oct 31.

Regulatory FOXP3+ T cells (Tregs) constitute 5% to 10% of T cells in the normal human skin. They play an important role in the induction and maintenance of immunological tolerance. The suppressive effects of these cells are exerted by...

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs' activation and function.

Postepy dermatologii i alergologii

Nedoszytko B, Sokołowska-Wojdyło M, Renke J, Lange M, Trzonkowski P, Sobjanek M, Szczerkowska-Dobosz A, Niedoszytko M, Górska A, Romantowski J, Skokowski J, Kalinowski L, Nowicki RJ.
PMID: 29422815
Postepy Dermatol Alergol. 2017 Dec;34(6):517-525. doi: 10.5114/pdia.2017.67053. Epub 2017 Dec 31.

Regulatory T cells (Tregs) represent a cell type that promotes immune tolerance to autologous components and maintains immune system homeostasis. The abnormal function of Tregs is relevant to the pathogenesis of several skin diseases like psoriasis, atopic dermatitis, systemic...

NK cell compartment in patients with coronary heart disease.

Immunity & ageing : I & A

Hak Ł, Myśliwska J, Więckiewicz J, Szyndler K, Trzonkowski P, Siebert J, Myśliwski A.
PMID: 17488493
Immun Ageing. 2007 May 08;4:3. doi: 10.1186/1742-4933-4-3.

BACKGROUND: Viral and bacterial infections have been considered as a risk factor for Coronary Heart Disease (CHD). NK cells, as a first line of defense against those infections, may play a role in CHD development. Thus, the main aim...

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part I: Treg properties and functions.

Postepy dermatologii i alergologii

Nedoszytko B, Lange M, Sokołowska-Wojdyło M, Renke J, Trzonkowski P, Sobjanek M, Szczerkowska-Dobosz A, Niedoszytko M, Górska A, Romantowski J, Skokowski J, Kalinowski L, Nowicki R.
PMID: 28951701
Postepy Dermatol Alergol. 2017 Aug;34(4):285-294. doi: 10.5114/ada.2017.69305. Epub 2017 Jul 31.

Regulatory T cells (Treg) can be divided into two types: the natural cells (tTreg), which arise in the thymus, and the induced cells (iTreg), which are produced in peripheral tissues during immune response. The most recently published studies indicate...

Corneal Allografts: Factors for and against Acceptance.

Journal of immunology research

Sakowska J, Glasner P, Zieliński M, Trzonkowski P, Glasner L.
PMID: 34642632
J Immunol Res. 2021 Oct 03;2021:5372090. doi: 10.1155/2021/5372090. eCollection 2021.

Cornea is one of the most commonly transplanted tissues worldwide. However, it is usually omitted in the field of transplantology. Transplantation of the cornea is performed to treat many ocular diseases. It restores eyesight significantly improving the quality of...

CD5-Positive B Lymphocytes after Kidney Transplantation.

Diagnostics (Basel, Switzerland)

Zieliński M, Tarasewicz A, Zielińska H, Jankowska M, Sakowska J, Dukat-Mazurek A, Moszkowska G, Rutkowski B, Dębska-Ślizień A, Trzonkowski P.
PMID: 34573916
Diagnostics (Basel). 2021 Aug 30;11(9). doi: 10.3390/diagnostics11091574.

Kidney transplantation is the treatment of choice for end-stage kidney diseases. Unfortunately, kidney allograft recipients rarely develop tolerance or accommodation and require life-long immunosuppression. Among many other regulatory mechanisms, CD5+ B lymphocytes (mainly B-1a) seem to be involved in...

Associations of TP53 codon 72 polymorphism with complications and comorbidities in patients with type 1 diabetes.

Journal of molecular medicine (Berlin, Germany)

Słomiński B, Skrzypkowska M, Ryba-Stanisławowska M, Myśliwiec M, Trzonkowski P.
PMID: 33495869
J Mol Med (Berl). 2021 May;99(5):675-683. doi: 10.1007/s00109-020-02035-1. Epub 2021 Jan 25.

Wild-type TP53 plays an important role in the regulation of immune response and systemic inflammation. In type 1 diabetes (T1D), TP53 pathways are upregulated and an increased susceptibility to apoptosis is observed. We hypothesize that TP53 codon 72 polymorphism...

CD8+ γδ T cells correlate with favorable prognostic factors in childhood acute lymphoblastic leukemia.

Archives of medical science : AMS

Pawlik-Gwozdecka D, Zieliński M, Sakowska J, Adamkiewicz-Drożyńska E, Trzonkowski P, Niedźwiecki M.
PMID: 33747294
Arch Med Sci. 2021 Feb 26;17(2):561-563. doi: 10.5114/aoms/132316. eCollection 2021.

No abstract available.

Immune Dysregulation in Patients With Chromosome 18q Deletions-Searching for Putative Loci for Autoimmunity and Immunodeficiency.

Frontiers in immunology

Hogendorf A, Zieliński M, Constantinou M, Śmigiel R, Wierzba J, Wyka K, Wędrychowicz A, Jakubiuk-Tomaszuk A, Budzynska E, Piotrowicz M, Lipska-Ziętkiewicz BS, Kaczorowska E, Cieślikowska A, Kutkowska-Kaźmierczak A, Fijak-Moskal J, Kugaudo M, Kosińska-Urbańska M, Szadkowska A, Borowiec M, Niedźwiecki M, Trzonkowski P, Młynarski W.
PMID: 34867966
Front Immunol. 2021 Nov 17;12:742834. doi: 10.3389/fimmu.2021.742834. eCollection 2021.

INTRODUCTION: Autoimmune disorders, IgA deficiency, and allergies seem to be common among individuals with 18q deletion syndrome [OMIM 601808]. We aimed to determine the prevalence, mechanism, and genetic background of autoimmunity, immune deficiency, and allergy in a cohort of...

Perinatal and neonatal outcome in patients with preeclampsia.

Ginekologia polska

Stefanska KA, Zielinski M, Jassem-Bobowicz J, Zamkowska D, Adamski P, Piekarska K, Jankowiak M, Leszczynska K, Swiatkowska-Stodulska R, Preis K, Trzonkowski P, Marek-Trzonkowska N.
PMID: 34105747
Ginekol Pol. 2021 Jun 09; doi: 10.5603/GP.a2021.0101. Epub 2021 Jun 09.

OBJECTIVES: Preeclampsia (PE) affects 2-5% of pregnant women. Hypertensive disorders of pregnancy are associated with adverse maternal and perinatal outcomes.MATERIAL AND METHODS: This study included 88 women showing gestational hypertension (GH) or PE symptoms, and their newborns.RESULTS: The rate...

Homeostatic proliferation of NK cells: friend or foe in cellular immunotherapy?.

Immunotherapy

Marek N, Trzonkowski P.
PMID: 21668309
Immunotherapy. 2011 Jun;3(6):727-9. doi: 10.2217/imt.11.53.

NK cells are an important tool in cellular immunotherapy owing to their role in infections and antitumor immunity. Until recently, these cells have been thought to be short-lived cytotoxic effectors that are cleared from the body soon after resolution...

Showing 1 to 12 of 21 entries