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Showing 1 to 12 of 14 entries
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United States multicenter study of factors predicting the persistence of GH deficiency during the transition period between childhood and adulthood.

International journal of pediatric endocrinology

Quigley CA, Zagar AJ, Liu CC, Brown DM, Huseman C, Levitsky L, Repaske DR, Tsalikian E, Chipman JJ.
PMID: 23406437
Int J Pediatr Endocrinol. 2013 Feb 13;2013(1):6. doi: 10.1186/1687-9856-2013-6.

BACKGROUND: Many patients with childhood-onset growth hormone (GH) deficiency do not fulfill diagnostic criteria for GH deficiency (GHD) after attainment of adult height and may not require long-term GH treatment. Patients with history of idiopathic GHD (IGHD) pose the...

Characterization of the Genetic Diversity Present in a Diverse Sesame Landrace Collection Based on Phenotypic Traits and EST-SSR Markers Coupled With an HRM Analysis.

Plants (Basel, Switzerland)

Stavridou E, Lagiotis G, Kalaitzidou P, Grigoriadis I, Bosmali I, Tsaliki E, Tsiotsiou S, Kalivas A, Ganopoulos I, Madesis P.
PMID: 33808174
Plants (Basel). 2021 Mar 30;10(4). doi: 10.3390/plants10040656.

A selection of sesame (

Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study.

BMC medicine

Sampson D, Yager TD, Fox B, Shallcross L, McHugh L, Seldon T, Rapisarda A, Hendriks RA, Brandon RB, Navalkar K, Simpson N, Stafford S, Gil E, Venturini C, Tsaliki E, Roe J, Chain B, Noursadeghi M.
PMID: 32690014
BMC Med. 2020 Jul 21;18(1):185. doi: 10.1186/s12916-020-01653-3.

BACKGROUND: There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions.METHODS: We used computational machine learning to derive a rule-out blood transcriptomic signature of bacterial...

Whole-genome resequencing of .

Horticulture research

Xanthopoulou A, Montero-Pau J, Mellidou I, Kissoudis C, Blanca J, Picó B, Tsaballa A, Tsaliki E, Dalakouras A, Paris HS, Ganopoulou M, Moysiadis T, Osathanunkul M, Tsaftaris A, Madesis P, Kalivas A, Ganopoulos I.
PMID: 31645952
Hortic Res. 2019 Aug 11;6:94. doi: 10.1038/s41438-019-0176-9. eCollection 2019.

No abstract available.

Human plasma-derived alpha.

Pediatric diabetes

Lagarde WH, Courtney KL, Reiner B, Steinmann K, Tsalikian E, Willi SM.
PMID: 33244872
Pediatr Diabetes. 2021 Mar;22(2):192-201. doi: 10.1111/pedi.13162. Epub 2020 Dec 13.

BACKGROUND: While circulating levels of alphaPARTICIPANTS: Seventy-six participants (aged 6-35 years) were randomized at 25 centers within 3 months of T1DM diagnosis.METHODS: A Phase II, multicenter, partially blinded, placebo-controlled, proof-of-concept study evaluating four dosing regimens of alphaRESULTS: Infusions were...

A Practical Approach to Using Trend Arrows on the Dexcom G5 CGM System to Manage Children and Adolescents With Diabetes.

Journal of the Endocrine Society

Laffel LM, Aleppo G, Buckingham BA, Forlenza GP, Rasbach LE, Tsalikian E, Weinzimer SA, Harris DR.
PMID: 29344578
J Endocr Soc. 2017 Nov 20;1(12):1461-1476. doi: 10.1210/js.2017-00389. eCollection 2017 Dec 01.

After assessing previously published methods, we developed a practical approach to adjusting insulin doses using rtCGM trend arrows in pediatric patients with diabetes.

IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.

JCI insight

Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Willi SM, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S.
PMID: 34747368
JCI Insight. 2021 Nov 08;6(21). doi: 10.1172/jci.insight.150074.

BackgroundIL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in newly diagnosed type 1...

Correction to: Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study.

BMC medicine

Sampson D, Yager TD, Fox B, Shallcross L, McHugh L, Seldon T, Rapisarda A, Hendriks RA, Brandon RB, Navalkar K, Simpson N, Stafford S, Gil E, Venturini C, Tsaliki E, Roe J, Chain B, Noursadeghi M.
PMID: 32919476
BMC Med. 2020 Sep 12;18(1):293. doi: 10.1186/s12916-020-01756-x.

An amendment to this paper has been published and can be accessed via the original article.

Eyebrow Height Changes with Aging: A Systematic Review and Meta-analysis.

Plastic and reconstructive surgery. Global open

Asaad M, Kelarji AB, Jawhar CS, Banuelos J, Taslakian E, Wahood W, Vyas KS, Sharaf B.
PMID: 31942395
Plast Reconstr Surg Glob Open. 2019 Sep 30;7(9):e2433. doi: 10.1097/GOX.0000000000002433. eCollection 2019 Sep.

The eyebrows play an important role in emotional facial expressions, nonverbal communication, and facial esthetics. A comprehensive understanding of the mechanisms underlying eyebrow aging is vital in allowing plastic surgeons to appropriately address these age-related changes and to recreate...

IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.

JCI insight

Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Willi SM, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S.
PMID: 34747368
JCI Insight. 2021 Nov 08;6(21). doi: 10.1172/jci.insight.150074.

BackgroundIL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in newly diagnosed type 1...

IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes.

JCI insight

Greenbaum CJ, Serti E, Lambert K, Weiner LJ, Kanaparthi S, Lord S, Gitelman SE, Wilson DM, Gaglia JL, Griffin KJ, Russell WE, Raskin P, Moran A, Willi SM, Tsalikian E, DiMeglio LA, Herold KC, Moore WV, Goland R, Harris M, Craig ME, Schatz DA, Baidal DA, Rodriguez H, Utzschneider KM, Nel HJ, Soppe CL, Boyle KD, Cerosaletti K, Keyes-Elstein L, Long SA, Thomas R, McNamara JG, Buckner JH, Sanda S.
PMID: 34747368
JCI Insight. 2021 Nov 08;6(21). doi: 10.1172/jci.insight.150074.

BackgroundIL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in newly diagnosed type 1...

Inter-individual methylation variability in differentially methylated regions between maternal whole blood and first trimester CVS.

Molecular cytogenetics

Ioannides M, Papageorgiou EA, Keravnou A, Tsaliki E, Spyrou C, Hadjidaniel M, Sismani C, Koumbaris G, Patsalis PC.
PMID: 25426166
Mol Cytogenet. 2014 Nov 01;7(1):73. doi: 10.1186/s13039-014-0073-8. eCollection 2014.

BACKGROUND: DNA methylation is the most studied form of epigenetic regulation, a process by which chromatin composition and transcription factor binding is altered to influence tissue specific gene expression and differentiation. Such tissue specific methylation patterns are investigated as...

Showing 1 to 12 of 14 entries