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Showing 1 to 12 of 38 entries
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Micro-eukaryotic diversity in hypolithons from miers valley, antarctica.

Biology

Gokul JK, Valverde A, Tuffin M, Cary SC, Cowan DA.
PMID: 24832664
Biology (Basel). 2013 Feb 22;2(1):331-40. doi: 10.3390/biology2010331.

The discovery of extensive and complex hypolithic communities in both cold and hot deserts has raised many questions regarding their ecology, biodiversity and relevance in terms of regional productivity. However, most hypolithic research has focused on the bacterial elements...

Leaching and antimicrobial properties of silver nanoparticles loaded onto natural zeolite clinoptilolite by ion exchange and wet impregnation.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering

Missengue RN, Musyoka NM, Madzivire G, Babajide O, Fatoba OO, Tuffin M, Petrik LF.
PMID: 26571140
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2016 Jan 28;51(2):97-104. doi: 10.1080/10934529.2015.1087731. Epub 2015 Nov 16.

This study aimed to compare the leaching and antimicrobial properties of silver that was loaded onto the natural zeolite clinoptilolite by ion exchange and wet impregnation. Silver ions were reduced using sodium borohydride (NaBH

Selection on horizontally transferred and duplicated genes in sinorhizobium (ensifer), the root-nodule symbionts of medicago.

Genome biology and evolution

Epstein B, Sadowsky MJ, Tiffin P.
PMID: 25991814
Genome Biol Evol. 2015 May 19;7(5):1329-30. doi: 10.1093/gbe/evu246.

No abstract available.

Multiple parameter vector bending and high-temperature sensors based on asymmetric multimode fiber Bragg gratings inscribed by an infrared femtosecond laser.

Optics letters

Yong Z, Zhan C, Lee J, Yin S, Ruffin P.
PMID: 16729073
Opt Lett. 2006 Jun 15;31(12):1794-6. doi: 10.1364/ol.31.001794.

We present a multiple parameter integrated fiber sensor that can detect vector bending and ambient temperature simultaneously with a single asymmetric multimode fiber Bragg grating. Multimode Bragg gratings were fabricated in an all-silica core fiber by an infrared femtosecond...

5-[6-1 -(Cyclohexyl-1 H-tetrazol-5-YL)hexyl]-1,8-naphthyridin-2-(1H)-one, SC-44368, a Potent Anti-aggregatory Agent which Selectively Inhibits Platelet Cyclic AMP Phosphodiesterase.

Platelets

Booth RF, Manley PW, Buckham SP, Hassall DG, Honey AC, Lad N, Lunt DO, Oswald S, Porter RA, Tuffin DP.
PMID: 21043905
Platelets. 1992;3(3):129-36. doi: 10.3109/09537109209013173.

SC-44368 (5-[6-(1-cyclohexyl-1H-tetrazol-5-y)hexyl]-1,8-naphthyridin-2(1H)-one) is a potent and selective competitive inhibitor of platelet cyclic AMP-dependent phosphodiesterase (cAMP-PDE) (Ki: 1.65 μM). For the phosphodiesterase isoenzyms from human platelets SC-44368 shows a 26-fold selectivity (IC50 ratio) for the inhibition of the cAMP-PDE over...

Chemically induced twist-bend nematic liquid crystals, liquid crystal dimers, and negative elastic constants.

Physical review. E, Statistical, nonlinear, and soft matter physics

Adlem K, Čopič M, Luckhurst GR, Mertelj A, Parri O, Richardson RM, Snow BD, Timimi BA, Tuffin RP, Wilkes D.
PMID: 24032852
Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Aug;88(2):022503. doi: 10.1103/PhysRevE.88.022503. Epub 2013 Aug 12.

Here we report the chemical induction of the twist-bend nematic phase in a nematic mixture of ether-linked liquid crystal dimers by the addition of a dimer with methylene links; all dimers have an odd number of groups in the...

Predicting need for hospital admission in patients with traumatic brain injury or skull fractures identified on CT imaging: a machine learning approach.

Emergency medicine journal : EMJ

Marincowitz C, Paton L, Lecky F, Tiffin P.
PMID: 33832924
Emerg Med J. 2021 Apr 08; doi: 10.1136/emermed-2020-210776. Epub 2021 Apr 08.

BACKGROUND: Patients with mild traumatic brain injury on CT scan are routinely admitted for inpatient observation. Only a small proportion of patients require clinical intervention. We recently developed a decision rule using traditional statistical techniques that found neurologically intact...

GlomSpheres as a 3D co-culture spheroid model of the kidney glomerulus for rapid drug-screening.

Communications biology

Tuffin J, Chesor M, Kuzmuk V, Johnson T, Satchell SC, Welsh GI, Saleem MA.
PMID: 34857869
Commun Biol. 2021 Dec 02;4(1):1351. doi: 10.1038/s42003-021-02868-7.

The glomerulus is the filtration unit of the kidney. Injury to any component of this specialised structure leads to impaired filtration and eventually fibrosis and chronic kidney disease. Current two and three dimensional (2D and 3D) models that attempt...

Long-term nitrofurantoin: an analysis of complication awareness, monitoring, and pulmonary injury cases.

BJGP open

Speirs TP, Tuffin N, Mundy-Baird F, Sakota H, Mulholland S, Westlake M, Lyon M, Medford AR, Sharp C, Darby M, Albur M, Keeley F, Burden H, Kenward C, Jonas E, Barratt S, Adamali HI.
PMID: 34407964
BJGP Open. 2021 Oct 26; doi: 10.3399/BJGPO.2021.0083. Epub 2021 Oct 26.

BACKGROUND: Long-term nitrofurantoin (NF) treatment can result in pulmonary and hepatic injury. Current guidelines do not outline the type or frequency of monitoring required for detection of these injuries.AIM: To assess 1) awareness of NF complications among prescribers; 2)...

GlomSpheres as a 3D co-culture spheroid model of the kidney glomerulus for rapid drug-screening.

Communications biology

Tuffin J, Chesor M, Kuzmuk V, Johnson T, Satchell SC, Welsh GI, Saleem MA.
PMID: 34857869
Commun Biol. 2021 Dec 02;4(1):1351. doi: 10.1038/s42003-021-02868-7.

The glomerulus is the filtration unit of the kidney. Injury to any component of this specialised structure leads to impaired filtration and eventually fibrosis and chronic kidney disease. Current two and three dimensional (2D and 3D) models that attempt...

Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce.

The Medical journal of Australia

Cheyne S, Lindley RI, Smallwood N, Tendal B, Chapman M, Fraile Navarro D, Good PD, Jenkin P, McDonald S, Morgan D, Murano M, Millard T, Naganathan V, Srikanth V, Tuffin P, Vogel J, White H, Chakraborty SP, Whiting E, William L, Yates PM, Callary M, Elliott J, Agar MR.
PMID: 34865227
Med J Aust. 2021 Dec 05; doi: 10.5694/mja2.51353. Epub 2021 Dec 05.

INTRODUCTION: Older people living with frailty and/or cognitive impairment who have coronavirus disease 2019 (COVID-19) experience higher rates of critical illness. There are also people who become critically ill with COVID-19 for whom a decision is made to take...

Dangerous Children: Assessment and Management of Risk.

Child and adolescent mental health

Tiffin P, Kaplan C.
PMID: 32797515
Child Adolesc Ment Health. 2004 May;9(2):56-64. doi: 10.1111/j.1475-3588.2004.00082.x.

BACKGROUND:   Workers in the field of child health appear to be presented with increasing numbers of young people who exhibit behaviours that pose a potential or actual risk to the safety of others.METHOD:   A review of the current literature...

Showing 1 to 12 of 38 entries