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Showing 1 to 9 of 9 entries
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Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation.

ACS medicinal chemistry letters

McElroy WT, Tan Z, Ho G, Paliwal S, Li G, Seganish WM, Tulshian D, Tata J, Fischmann TO, Sondey C, Bian H, Bober L, Jackson J, Garlisi CG, Devito K, Fossetta J, Lundell D, Niu X.
PMID: 26101573
ACS Med Chem Lett. 2015 May 12;6(6):677-82. doi: 10.1021/acsmedchemlett.5b00106. eCollection 2015 Jun 11.

IRAK4 is a critical upstream kinase in the IL-1R/TLR signaling pathway. Inhibition of IRAK4 is hypothesized to be beneficial in the treatment of autoimmune related disorders. A screening campaign identified a pyrazole class of IRAK4 inhibitors that were determined...

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McElroy WT, Tan Z, Ho G, et al. Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation. ACS Med Chem Lett. 2015;6(6):677-82doi: 10.1021/acsmedchemlett.5b00106.
McElroy, W. T., Tan, Z., Ho, G., Paliwal, S., Li, G., Seganish, W. M., Tulshian, D., Tata, J., Fischmann, T. O., Sondey, C., Bian, H., Bober, L., Jackson, J., Garlisi, C. G., Devito, K., Fossetta, J., Lundell, D., & Niu, X. (2015). Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation. ACS medicinal chemistry letters, 6(6), 677-82. https://doi.org/10.1021/acsmedchemlett.5b00106
McElroy, William T, et al. "Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation." ACS medicinal chemistry letters vol. 6,6 (2015): 677-82. doi: https://doi.org/10.1021/acsmedchemlett.5b00106
McElroy WT, Tan Z, Ho G, Paliwal S, Li G, Seganish WM, Tulshian D, Tata J, Fischmann TO, Sondey C, Bian H, Bober L, Jackson J, Garlisi CG, Devito K, Fossetta J, Lundell D, Niu X. Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation. ACS Med Chem Lett. 2015 May 12;6(6):677-82. doi: 10.1021/acsmedchemlett.5b00106. eCollection 2015 Jun 11. PMID: 26101573; PMCID: PMC4468401.
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DSM-IV schizotypal personality disorder: a taxometric analysis among individuals with and without substance use disorders in the general population.

Mental health and substance use : dual diagnosis

Kerridge BT, Saha TD, Hasin DS.
PMID: 26322122
Ment Health Subst Use. 2014;7(4):446-460. doi: 10.1080/17523281.2014.946076.

This study examined the underlying structure of DSM-IV schizotypal personality disorder (SPD) among individuals with and without a substance use disorder. Using a nationally representative sample of U.S. adults, taxometric analyses were conducted on SPD in the total sample...

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Kerridge BT, Saha TD, Hasin DS. DSM-IV schizotypal personality disorder: a taxometric analysis among individuals with and without substance use disorders in the general population. Ment Health Subst Use. 2014;7(4):446-460doi: 10.1080/17523281.2014.946076.
Kerridge, B. T., Saha, T. D., & Hasin, D. S. (2014). DSM-IV schizotypal personality disorder: a taxometric analysis among individuals with and without substance use disorders in the general population. Mental health and substance use : dual diagnosis, 7(4), 446-460. https://doi.org/10.1080/17523281.2014.946076
Kerridge, Bradley T, et al. "DSM-IV schizotypal personality disorder: a taxometric analysis among individuals with and without substance use disorders in the general population." Mental health and substance use : dual diagnosis vol. 7,4 (2014): 446-460. doi: https://doi.org/10.1080/17523281.2014.946076
Kerridge BT, Saha TD, Hasin DS. DSM-IV schizotypal personality disorder: a taxometric analysis among individuals with and without substance use disorders in the general population. Ment Health Subst Use. 2014;7(4):446-460. doi: 10.1080/17523281.2014.946076. PMID: 26322122; PMCID: PMC4549000.
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Prevalence, correlates, disability, and comorbidity of DSM-IV schizotypal personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related conditions.

Primary care companion to the Journal of clinical psychiatry

Pulay AJ, Stinson FS, Dawson DA, Goldstein RB, Chou SP, Huang B, Saha TD, Smith SM, Pickering RP, Ruan WJ, Hasin DS, Grant BF.
PMID: 19617934
Prim Care Companion J Clin Psychiatry. 2009;11(2):53-67. doi: 10.4088/pcc.08m00679.

OBJECTIVE: To present nationally representative findings on the prevalence, correlates, and comorbidity of and disability associated with DSM-IV schizotypal personality disorder (SPD).METHOD: This study used the 2004-2005 Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions, which targeted...

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Pulay AJ, Stinson FS, Dawson DA, et al. Prevalence, correlates, disability, and comorbidity of DSM-IV schizotypal personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related conditions. Prim Care Companion J Clin Psychiatry. 2009;11(2):53-67doi: 10.4088/pcc.08m00679.
Pulay, A. J., Stinson, F. S., Dawson, D. A., Goldstein, R. B., Chou, S. P., Huang, B., Saha, T. D., Smith, S. M., Pickering, R. P., Ruan, W. J., Hasin, D. S., & Grant, B. F. (2009). Prevalence, correlates, disability, and comorbidity of DSM-IV schizotypal personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related conditions. Primary care companion to the Journal of clinical psychiatry, 11(2), 53-67. https://doi.org/10.4088/pcc.08m00679
Pulay, Attila J, et al. "Prevalence, correlates, disability, and comorbidity of DSM-IV schizotypal personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related conditions." Primary care companion to the Journal of clinical psychiatry vol. 11,2 (2009): 53-67. doi: https://doi.org/10.4088/pcc.08m00679
Pulay AJ, Stinson FS, Dawson DA, Goldstein RB, Chou SP, Huang B, Saha TD, Smith SM, Pickering RP, Ruan WJ, Hasin DS, Grant BF. Prevalence, correlates, disability, and comorbidity of DSM-IV schizotypal personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related conditions. Prim Care Companion J Clin Psychiatry. 2009;11(2):53-67. doi: 10.4088/pcc.08m00679. PMID: 19617934; PMCID: PMC2707116.
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Double Intussuscepted Patent Vitellointestinal Duct.

Journal of Indian Association of Pediatric Surgeons

Basu S, Makan A, Tulsian A, Joseph V, Gandhi S, Shenoy NS, Shah H.
PMID: 34728931
J Indian Assoc Pediatr Surg. 2021 Sep-Oct;26(5):363-364. doi: 10.4103/jiaps.JIAPS_9_21. Epub 2021 Sep 16.

No abstract available.

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Basu S, Makan A, Tulsian A, et al. Double Intussuscepted Patent Vitellointestinal Duct. J Indian Assoc Pediatr Surg. 2021;26(5):363-364doi: 10.4103/jiaps.JIAPS_9_21.
Basu, S., Makan, A., Tulsian, A., Joseph, V., Gandhi, S., Shenoy, N. S., & Shah, H. (2021). Double Intussuscepted Patent Vitellointestinal Duct. Journal of Indian Association of Pediatric Surgeons, 26(5), 363-364. https://doi.org/10.4103/jiaps.JIAPS_9_21
Basu, Syamantak, et al. "Double Intussuscepted Patent Vitellointestinal Duct." Journal of Indian Association of Pediatric Surgeons vol. 26,5 (2021): 363-364. doi: https://doi.org/10.4103/jiaps.JIAPS_9_21
Basu S, Makan A, Tulsian A, Joseph V, Gandhi S, Shenoy NS, Shah H. Double Intussuscepted Patent Vitellointestinal Duct. J Indian Assoc Pediatr Surg. 2021 Sep-Oct;26(5):363-364. doi: 10.4103/jiaps.JIAPS_9_21. Epub 2021 Sep 16. PMID: 34728931; PMCID: PMC8515521.
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An Eye on the Future of COVID-19: Prediction of Likely Positive Cases and Fatality in India over a 30-Day Horizon Using the Prophet Model.

Disaster medicine and public health preparedness

Tulshyan V, Sharma D, Mittal M.
PMID: 33203489
Disaster Med Public Health Prep. 2020 Nov 18;1-7. doi: 10.1017/dmp.2020.444. Epub 2020 Nov 18.

OBJECTIVE: The coronavirus disease (COVID-19) pandemic was initiated in Wuhan Province of mainland China in December 2019 and has spread over the world. This study analyzes the effects of COVID-19 based on likely positive cases and fatality in India...

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Tulshyan V, Sharma D, Mittal M. An Eye on the Future of COVID-19: Prediction of Likely Positive Cases and Fatality in India over a 30-Day Horizon Using the Prophet Model. Disaster Med Public Health Prep. 2020;1-7doi: 10.1017/dmp.2020.444.
Tulshyan, V., Sharma, D., & Mittal, M. (2020). An Eye on the Future of COVID-19: Prediction of Likely Positive Cases and Fatality in India over a 30-Day Horizon Using the Prophet Model. Disaster medicine and public health preparedness, 1-7. https://doi.org/10.1017/dmp.2020.444
Tulshyan, Vatsal, et al. "An Eye on the Future of COVID-19: Prediction of Likely Positive Cases and Fatality in India over a 30-Day Horizon Using the Prophet Model." Disaster medicine and public health preparedness vol. (2020): 1-7. doi: https://doi.org/10.1017/dmp.2020.444
Tulshyan V, Sharma D, Mittal M. An Eye on the Future of COVID-19: Prediction of Likely Positive Cases and Fatality in India over a 30-Day Horizon Using the Prophet Model. Disaster Med Public Health Prep. 2020 Nov 18;1-7. doi: 10.1017/dmp.2020.444. Epub 2020 Nov 18. PMID: 33203489; PMCID: PMC7985632.
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Outcome analysis of single-stage transanal endorectal pull through in selected patients with hirschsprung disease.

African journal of paediatric surgery : AJPS

Gandhi S, Makan A, Shenoy NS, Basu S, Tulsian A, Shah H.
PMID: 34916354
Afr J Paediatr Surg. 2022 Jan-Mar;19(1):56-59. doi: 10.4103/ajps.AJPS_137_20.

BACKGROUND: Hirschsprung disease is a notable cause of neonatal intestinal obstruction and constipation in older children. Transanal endorectal pull through (TEPT) is a newer technique of definitive management as against staged procedures. The aim of our study is to...

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Gandhi S, Makan A, Shenoy NS, et al. Outcome analysis of single-stage transanal endorectal pull through in selected patients with hirschsprung disease. Afr J Paediatr Surg. 2022;19(1):56-59doi: 10.4103/ajps.AJPS_137_20.
Gandhi, S., Makan, A., Shenoy, N. S., Basu, S., Tulsian, A., & Shah, H. (2022). Outcome analysis of single-stage transanal endorectal pull through in selected patients with hirschsprung disease. African journal of paediatric surgery : AJPS, 19(1), 56-59. https://doi.org/10.4103/ajps.AJPS_137_20
Gandhi, Suraj, et al. "Outcome analysis of single-stage transanal endorectal pull through in selected patients with hirschsprung disease." African journal of paediatric surgery : AJPS vol. 19,1 (2022): 56-59. doi: https://doi.org/10.4103/ajps.AJPS_137_20
Gandhi S, Makan A, Shenoy NS, Basu S, Tulsian A, Shah H. Outcome analysis of single-stage transanal endorectal pull through in selected patients with hirschsprung disease. Afr J Paediatr Surg. 2022 Jan-Mar;19(1):56-59. doi: 10.4103/ajps.AJPS_137_20. PMID: 34916354.
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Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors.

ACS medicinal chemistry letters

Seganish WM, Fischmann TO, Sherborne B, Matasi J, Lavey B, McElroy WT, Tulshian D, Tata J, Sondey C, Garlisi CG, Devito K, Fossetta J, Lundell D, Niu X.
PMID: 26288698
ACS Med Chem Lett. 2015 Jul 12;6(8):942-7. doi: 10.1021/acsmedchemlett.5b00279. eCollection 2015 Aug 13.

We report the identification and synthesis of a series of aminopyrimidin-4-one IRAK4 inhibitors. Through high throughput screening, an aminopyrimidine hit was identified and modified via structure enabled design to generate a new, potent, and kinase selective pyrimidin-4-one chemotype. This...

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Seganish WM, Fischmann TO, Sherborne B, et al. Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors. ACS Med Chem Lett. 2015;6(8):942-7doi: 10.1021/acsmedchemlett.5b00279.
Seganish, W. M., Fischmann, T. O., Sherborne, B., Matasi, J., Lavey, B., McElroy, W. T., Tulshian, D., Tata, J., Sondey, C., Garlisi, C. G., Devito, K., Fossetta, J., Lundell, D., & Niu, X. (2015). Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors. ACS medicinal chemistry letters, 6(8), 942-7. https://doi.org/10.1021/acsmedchemlett.5b00279
Seganish, W Michael, et al. "Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors." ACS medicinal chemistry letters vol. 6,8 (2015): 942-7. doi: https://doi.org/10.1021/acsmedchemlett.5b00279
Seganish WM, Fischmann TO, Sherborne B, Matasi J, Lavey B, McElroy WT, Tulshian D, Tata J, Sondey C, Garlisi CG, Devito K, Fossetta J, Lundell D, Niu X. Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors. ACS Med Chem Lett. 2015 Jul 12;6(8):942-7. doi: 10.1021/acsmedchemlett.5b00279. eCollection 2015 Aug 13. PMID: 26288698; PMCID: PMC4538434.
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Strong and weak cross-inheritance of substance use disorders in a nationally representative sample.

Molecular psychiatry

Zhang H, Grant BF, Hodgkinson CA, Ruan WJ, Kerridge BT, Huang B, Saha TD, Fan AZ, Wilson V, Jung J, Parsian A, Goldman D, Chou SP.
PMID: 34759357
Mol Psychiatry. 2021 Nov 10; doi: 10.1038/s41380-021-01370-0. Epub 2021 Nov 10.

Substance use disorders (SUDs) are moderately to highly heritable and are in part cross-transmitted genetically, as observed in twin and family studies. We performed exome-focused genotyping to examine the cross-transmission of four SUDs: alcohol use disorder (AUD, n =...

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Zhang H, Grant BF, Hodgkinson CA, et al. Strong and weak cross-inheritance of substance use disorders in a nationally representative sample. Mol Psychiatry. 2021;doi: 10.1038/s41380-021-01370-0.
Zhang, H., Grant, B. F., Hodgkinson, C. A., Ruan, W. J., Kerridge, B. T., Huang, B., Saha, T. D., Fan, A. Z., Wilson, V., Jung, J., Parsian, A., Goldman, D., & Chou, S. P. (2021). Strong and weak cross-inheritance of substance use disorders in a nationally representative sample. Molecular psychiatry, . https://doi.org/10.1038/s41380-021-01370-0
Zhang, Haitao, et al. "Strong and weak cross-inheritance of substance use disorders in a nationally representative sample." Molecular psychiatry vol. (2021). doi: https://doi.org/10.1038/s41380-021-01370-0
Zhang H, Grant BF, Hodgkinson CA, Ruan WJ, Kerridge BT, Huang B, Saha TD, Fan AZ, Wilson V, Jung J, Parsian A, Goldman D, Chou SP. Strong and weak cross-inheritance of substance use disorders in a nationally representative sample. Mol Psychiatry. 2021 Nov 10; doi: 10.1038/s41380-021-01370-0. Epub 2021 Nov 10. PMID: 34759357.
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Hypoxia-inducible factor 1-alpha enhances the secretome to rejuvenate adult cardiosphere-derived cells.

The Journal of thoracic and cardiovascular surgery

Saha P, Kim M, Tulshyan A, Guo Y, Mishra R, Li D, Civin CI, Kaushal S, Sharma S.
PMID: 34465468
J Thorac Cardiovasc Surg. 2021 Jul 17; doi: 10.1016/j.jtcvs.2021.07.015. Epub 2021 Jul 17.

OBJECTIVE: After cardiac injury, endogenous repair mechanisms are ineffective. However, cell-based therapies provide a promising clinical intervention based on their ability to restore and remodel injured myocardium due to their paracrine factors. Recent clinical trials have demonstrated that adult...

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Saha P, Kim M, Tulshyan A, et al. Hypoxia-inducible factor 1-alpha enhances the secretome to rejuvenate adult cardiosphere-derived cells. J Thorac Cardiovasc Surg. 2021;doi: 10.1016/j.jtcvs.2021.07.015.
Saha, P., Kim, M., Tulshyan, A., Guo, Y., Mishra, R., Li, D., Civin, C. I., Kaushal, S., & Sharma, S. (2021). Hypoxia-inducible factor 1-alpha enhances the secretome to rejuvenate adult cardiosphere-derived cells. The Journal of thoracic and cardiovascular surgery, . https://doi.org/10.1016/j.jtcvs.2021.07.015
Saha, Progyaparamita, et al. "Hypoxia-inducible factor 1-alpha enhances the secretome to rejuvenate adult cardiosphere-derived cells." The Journal of thoracic and cardiovascular surgery vol. (2021). doi: https://doi.org/10.1016/j.jtcvs.2021.07.015
Saha P, Kim M, Tulshyan A, Guo Y, Mishra R, Li D, Civin CI, Kaushal S, Sharma S. Hypoxia-inducible factor 1-alpha enhances the secretome to rejuvenate adult cardiosphere-derived cells. J Thorac Cardiovasc Surg. 2021 Jul 17; doi: 10.1016/j.jtcvs.2021.07.015. Epub 2021 Jul 17. PMID: 34465468.
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Showing 1 to 9 of 9 entries