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Showing 1 to 12 of 44 entries
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Invasive Candida Infections in Liver Transplant Recipients: Clinical Features and Risk Factors for Mortality.

Transplantation direct

Bassetti M, Peghin M, Carnelutti A, Righi E, Merelli M, Ansaldi F, Trucchi C, Alicino C, Sartor A, Wauters J, Lagrou K, Tascini C, Menichetti F, Mesini A, De Rosa FG, Lagunes L, Rello J, Colombo AL, Vena A, Munoz P, Tumbarello M, Sganga G, Martin-Loeches I, Viscoli C.
PMID: 28573191
Transplant Direct. 2017 Apr 18;3(5):e156. doi: 10.1097/TXD.0000000000000673. eCollection 2017 May.

BACKGROUND: Invasive fungal infections remain a leading cause of morbidity and mortality among liver transplant recipients (LTRs). In this patient population, invasive Candida infections (ICIs) account for the large majority of cases. To date, only small studies and case-series...

[Bacterial pneumonia in HIV-infected patients].

Le infezioni in medicina

De Gaetano Donati K, Tacconelli E, Tumbarello M, Bertagnolo S, Ardito F, Pirronti T, Cauda R.
PMID: 12759590
Infez Med. 1999;7(2):108-112.

This case-control study assessed risk factors and prognostic indicators of 350 episodes of bacterial pneumonia in 285 HIV-infected patients. On univariate analysis, intravenous drug abuse (p

Morgagni's diaphragmatic hernia mimicking a severe congenital heart disease in a newborn: a case report.

Journal of medical case reports

Bassareo PP, Neroni P, Montis S, Tumbarello R.
PMID: 21143832
J Med Case Rep. 2010 Dec 08;4:395. doi: 10.1186/1752-1947-4-395.

INTRODUCTION: Morgagni's congenital diaphragmatic defect is a rare malformation, the diagnosis of which, as in our case report, may be problematic. To the best of our knowledge, this is the first report of this kind of hernia presenting with...

Correction to: Treatment and mortality of Klebslella pneumoniae infections in critically ill patients: should we do and predict them better?.

Intensive care medicine

Bassetti M, Akova M, Tumbarello M.
PMID: 30413839
Intensive Care Med. 2018 Dec;44(12):2324. doi: 10.1007/s00134-018-5411-6.

The original version of this article unfortunately contained a mistake.

A new call for influenza and pneumococcal vaccinations during COVID-19 pandemic in Italy: A SIP/IRS (Italian Respiratory Society) and SITA (Italian Society of Antiinfective therapy) statement.

Respiratory medicine

Blasi F, Di Pasquale M, Gramegna A, Viale P, Iacobello C, Gori A, Tumbarello M, Esposito S, Richeldi L, Bassetti M.
PMID: 34788734
Respir Med. 2021 Dec;190:106674. doi: 10.1016/j.rmed.2021.106674. Epub 2021 Nov 01.

Influenza and pneumococcal disease represent a well-known burden on healthcare systems worldwide, as well as they still have an attributed morbidity and mortality, especially in elderly individuals and vulnerable populations. In the context of the ongoing pandemic of COVID-19,...

Factors Associated with Inadequate Intravenous Colistin Dosages: Post Hoc Analysis of a Multicenter, Cross-Sectional Study.

Antibiotics (Basel, Switzerland)

Giacobbe DR, Mirabella M, Rinaldi M, Losito AR, Raffaelli F, Del Puente F, Saffioti C, Mikulska M, Giannella M, Viale P, Tumbarello M, Bassetti M, On Behalf Of Sita Giovani Young Investigators Group Of The Società Italiana Terapia Antinfettiva And.
PMID: 34943767
Antibiotics (Basel). 2021 Dec 19;10(12). doi: 10.3390/antibiotics10121554.

Colistin is a last-resort agent for the treatment of infections due to Gram-negative bacteria with difficult-to-treat resistance. The primary objective of this post hoc analysis of a cross-sectional study conducted in 22 Italian hospitals was to assess factors associated...

Evaluating Cefiderocol in the Treatment of Multidrug-Resistant Gram-Negative Bacilli: A Review of the Emerging Data.

Infection and drug resistance

Giacobbe DR, Ciacco E, Girmenia C, Pea F, Rossolini GM, Sotgiu G, Tascini C, Tumbarello M, Viale P, Bassetti M.
PMID: 33402840
Infect Drug Resist. 2020 Dec 29;13:4697-4711. doi: 10.2147/IDR.S205309. eCollection 2020.

Infections due to multidrug-resistant Gram-negative bacteria (MDR-GNB), especially when carbapenem resistant, have been very difficult to manage in the last fifteen years, owing to the paucity of dependable therapeutic options. Cefiderocol is a siderophore cephalosporin recently approved by the...

Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing .

Open forum infectious diseases

Bassetti M, Vena A, Giacobbe DR, Falcone M, Tiseo G, Giannella M, Pascale R, Meschiari M, Digaetano M, Oliva A, Rovelli C, Carannante N, Losito AR, Carbonara S, Mariani MF, Mastroianni A, Angarano G, Tumbarello M, Tascini C, Grossi P, Mastroianni CM, Mussini C, Viale P, Menichetti F, Viscoli C, Russo A.
PMID: 32462046
Open Forum Infect Dis. 2020 Apr 21;7(5):ofaa139. doi: 10.1093/ofid/ofaa139. eCollection 2020 May.

BACKGROUND: Few data are reported in the literature about the outcome of patients with severe extended-spectrum β-lactamase-producing METHODS: A multicenter retrospective study was performed in Italy (June 2016-June 2019). Successful clinical outcome was defined as complete resolution of clinical...

Carbapenem-Resistant .

Open forum infectious diseases

Alexander EL, Loutit J, Tumbarello M, Wunderink R, Felton T, Daikos G, Fusaro K, White D, Zhang S, Dudley MN.
PMID: 28584849
Open Forum Infect Dis. 2017 Jun 01;4(2):ofx063. doi: 10.1093/ofid/ofx063. eCollection 2017.

BACKGROUND: The increasing incidence of multidrug-resistant Gram negatives, such as carbapenem-resistant METHODS: This was a retrospective study at 22 centers in 4 countries. Baseline data, treatment, and outcomes were collected in patients with complicated urinary tract infection (cUTI)/acute pyelonephritis...

Pharmacokinetics of high-dose tigecycline in critically ill patients with severe infections.

Annals of intensive care

De Pascale G, Lisi L, Ciotti GMP, Vallecoccia MS, Cutuli SL, Cascarano L, Gelormini C, Bello G, Montini L, Carelli S, Di Gravio V, Tumbarello M, Sanguinetti M, Navarra P, Antonelli M.
PMID: 32661791
Ann Intensive Care. 2020 Jul 13;10(1):94. doi: 10.1186/s13613-020-00715-2.

BACKGROUND: In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective observational study to describe the pharmacokinetic/pharmacodynamic (PK/PD) profile of...

Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.

Frontiers in cell and developmental biology

Assar EA, Tumbarello DA.
PMID: 32850845
Front Cell Dev Biol. 2020 Aug 04;8:733. doi: 10.3389/fcell.2020.00733. eCollection 2020.

Autophagy is an essential catabolic intracellular pathway that maintains homeostasis by degrading long-lived proteins, damaged organelles, and provides an energy source during nutrient starvation. It is now understood that autophagy has discrete functions as a selective lysosomal degradation pathway...

Esthesioneuroblastoma in an HIV-1 Infected Patient: Case Report.

Skull base reports

Trecarichi EM, Galli J, Tamburrini E, de Donati KG, Scoppettuolo G, Colosimo C, Pierconti F, Paludetti G, Tumbarello M.
PMID: 23984215
Skull Base Rep. 2011 Nov;1(2):129-32. doi: 10.1055/s-0031-1284208. Epub 2011 Jul 22.

Esthesioneuroblastoma (ENB) is an uncommon malignant tumor derived from the specialized neuroepithelium of the upper nasal cavity. The largest case series and meta-analyses suggest the combination of surgery and radiotherapy as the gold standard treatment for ENB. However, an...

Showing 1 to 12 of 44 entries