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Showing 1 to 12 of 28 entries
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Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population.

Parkinson's disease

Lange J, Lunde KA, Sletten C, Møller SG, Tysnes OB, Alves G, Larsen JP, Maple-Grødem J.
PMID: 26788404
Parkinsons Dis. 2015;2015:973298. doi: 10.1155/2015/973298. Epub 2015 Dec 14.

Background. Parkinson's disease (PD) and Alzheimer's disease (AD) share pathological features, including amyloid-beta pathology. Amyloid-beta peptide is generated by sequential proteolysis of amyloid precursor protein (APP), and genetic variations in the processing pathway genes have been found to increase...

Use of Oxidative Stress Responses to Determine the Efficacy of Inactivation Treatments on .

Microorganisms

Temesgen TT, Tysnes KR, Robertson LJ.
PMID: 34361899
Microorganisms. 2021 Jul 08;9(7). doi: 10.3390/microorganisms9071463.

No abstract available.

Early constipation predicts faster dementia onset in Parkinson's disease.

NPJ Parkinson's disease

Camacho M, Macleod AD, Maple-Grødem J, Evans JR, Breen DP, Cummins G, Wijeyekoon RS, Greenland JC, Alves G, Tysnes OB, Lawson RA, Barker RA, Williams-Gray CH.
PMID: 34039994
NPJ Parkinsons Dis. 2021 May 26;7(1):45. doi: 10.1038/s41531-021-00191-w.

Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson's Incidence Cohorts Collaboration,...

The impact of common genetic variants in cognitive decline in the first seven years of Parkinson's disease: A longitudinal observational study.

Neuroscience letters

Chung J, Ushakova A, Doitsidou M, Tzoulis C, Tysnes OB, Dalen I, Pedersen KF, Alves G, Maple-Grødem J.
PMID: 34509566
Neurosci Lett. 2021 Nov 01;764:136243. doi: 10.1016/j.neulet.2021.136243. Epub 2021 Sep 10.

INTRODUCTION: Cognitive impairment is a common feature of Parkinson's disease and is a significant determinant of patients' quality of life and dependence. The pattern and progression of cognitive symptoms vary greatly between individuals, and genetic biomarkers may help to...

Gastrointestinal nematodes and Fasciola hepatica in Norwegian cattle herds: a questionnaire to investigate farmers' perceptions and control strategies.

Acta veterinaria Scandinavica

Opsal T, Toftaker I, Nødtvedt A, Robertson LJ, Tysnes KR, Woolsey I, Hektoen L.
PMID: 34863233
Acta Vet Scand. 2021 Dec 04;63(1):52. doi: 10.1186/s13028-021-00618-7.

BACKGROUND: Pasture management influences the prevalence and impact of the pasture parasites (PP) in cattle herds, which cause production-limiting disease worldwide. Evaluating farmer management strategies is vital when considering sustainable PP control practices. The aim of this questionnaire-based study...

Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson's disease brain.

Molecular neurodegeneration

Toker L, Tran GT, Sundaresan J, Tysnes OB, Alves G, Haugarvoll K, Nido GS, Dölle C, Tzoulis C.
PMID: 33947435
Mol Neurodegener. 2021 May 05;16(1):31. doi: 10.1186/s13024-021-00450-7.

BACKGROUND: Parkinson's disease (PD) is a complex, age-related neurodegenerative disorder of largely unknown etiology. PD is strongly associated with mitochondrial respiratory dysfunction, which can lead to epigenetic dysregulation and specifically altered histone acetylation. Nevertheless, and despite the emerging role...

Heterogeneous effects of bradykinin and a23187 on glioma growth, migration and invasion.

International journal of oncology

Nygaard S, Laerum O, Tysnes O.
PMID: 21559559
Int J Oncol. 1994 Jul;5(1):69-75. doi: 10.3892/ijo.5.1.69.

To evaluate the role of receptor interaction and calcium mobilization in growth of gliomas, we examined the effects of bradykinin (BK) and the calcium ionophore A23187 on growth, migration and invasion of the continuous human glioma cell lines GaMG,...

[Not Available].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke

Tysnes OB, Næss H, Owe J.
PMID: 27272355
Tidsskr Nor Laegeforen. 2016 Jun 07;136(10):892. doi: 10.4045/tidsskr.16.0409. eCollection 2016 Jun.

No abstract available.

Association of .

Frontiers in neurology

Szwedo AA, Pedersen CC, Ushakova A, Forsgren L, Tysnes OB, Counsell CE, Alves G, Lange J, Macleod AD, Maple-Grødem J.
PMID: 33643180
Front Neurol. 2021 Feb 10;11:620585. doi: 10.3389/fneur.2020.620585. eCollection 2020.

No abstract available.

Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson's Disease Cohorts.

Journal of Parkinson's disease

Maple-Grødem J, Paul KC, Dalen I, Ngo KJ, Wong D, Macleod AD, Counsell CE, Bäckström D, Forsgren L, Tysnes OB, Kusters CDJ, Fogel BL, Bronstein JM, Ritz B, Alves G.
PMID: 34275908
J Parkinsons Dis. 2021;11(4):1569-1578. doi: 10.3233/JPD-212657.

BACKGROUND: Motor complications are a consequence of the chronic dopaminergic treatment of Parkinson's disease (PD) and include levodopa-induced dyskinesia (LIDs) and motor fluctuations (MF). Currently, evidence is on lacking whether patients with GBA-associated PD differ in their risk of...

The impact of common genetic variants in cognitive decline in the first seven years of Parkinson's disease: A longitudinal observational study.

Neuroscience letters

Chung J, Ushakova A, Doitsidou M, Tzoulis C, Tysnes OB, Dalen I, Pedersen KF, Alves G, Maple-Grødem J.
PMID: 34509566
Neurosci Lett. 2021 Nov 01;764:136243. doi: 10.1016/j.neulet.2021.136243. Epub 2021 Sep 10.

INTRODUCTION: Cognitive impairment is a common feature of Parkinson's disease and is a significant determinant of patients' quality of life and dependence. The pattern and progression of cognitive symptoms vary greatly between individuals, and genetic biomarkers may help to...

Translation, cultural adaptation, and validation of a screening test for cognitive and behavioural changes in amyotrophic lateral sclerosis.

Disability and rehabilitation

Taule T, Morland AS, Aßmus J, Tysnes OB, Rekand T.
PMID: 34726988
Disabil Rehabil. 2021 Nov 02;1-9. doi: 10.1080/09638288.2021.1980621. Epub 2021 Nov 02.

PURPOSE: To describe challenges of translating and culturally adapting the Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis (ALS) Screen into Norwegian (ECAS-N), evaluate its content validity; provide age- and education-balanced norms for verbal fluency and cut-off values for abnormal...

Showing 1 to 12 of 28 entries