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Showing 1 to 12 of 70 entries
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Cost-Utility Analysis of Certolizumab Pegol Plus Methotrexate for the Treatment of Moderate-To-Severe Active Rheumatoid Arthritis In Greece.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Tzanetakos C, Maniadakis N, Kourlaba G, Tzioufas A, Goules A, Theodoratou T, Christou P.
PMID: 27200853
Value Health. 2014 Nov;17(7):A382. doi: 10.1016/j.jval.2014.08.2624. Epub 2014 Oct 26.

No abstract available.

Lung compliance and chronic obstructive pulmonary disease.

Pulmonary medicine

Papandrinopoulou D, Tzouda V, Tsoukalas G.
PMID: 23150821
Pulm Med. 2012;2012:542769. doi: 10.1155/2012/542769. Epub 2012 Oct 22.

Chronic obstructive pulmonary disease, namely, pulmonary emphysema and chronic bronchitis, is a chronic inflammatory response of the airways to noxious particles or gases, with resulting pathological and pathophysiological changes in the lung. The main pathophysiological aspects of the disease...

The rat adequately reflects human responses to exercise in blood biochemical profile: a comparative study.

Physiological reports

Goutianos G, Tzioura A, Kyparos A, Paschalis V, Margaritelis NV, Veskoukis AS, Zafeiridis A, Dipla K, Nikolaidis MG, Vrabas IS.
PMID: 25677548
Physiol Rep. 2015 Feb 12;3(2). doi: 10.14814/phy2.12293. Print 2015 Feb 01.

Animal models are widely used in biology and the findings of animal research are traditionally projected to humans. However, recent publications have raised concerns with regard to what extent animals and humans respond similar to physiological stimuli. Original data...

International Consensus on ANCA Testing in Eosinophilic Granulomatosis with Polyangiitis.

American journal of respiratory and critical care medicine

Moiseev S, Bossuyt X, Arimura Y, Blockmans D, Csernok E, Damoiseaux J, Emmi G, Flores-Suárez LF, Hellmich B, Jayne D, Jennette JC, Little MA, Mohammad AJ, Moosig F, Novikov P, Pagnoux C, Radice A, Sada KE, Segelmark M, Shoenfeld Y, Sinico RA, Specks U, Terrier B, Tzioufas AG, Vaglio A, Zhao MH, Cohen Tervaert JW.
PMID: 32584187
Am J Respir Crit Care Med. 2020 Jun 25; doi: 10.1164/rccm.202005-1628SO. Epub 2020 Jun 25.

An international consensus on anti-neutrophil cytoplasm antibodies (ANCA) testing in eosinophilic granulomatosis with polyangiitis (EGPA) is presented. ANCA, specific for myeloperoxidase (MPO), can be detected in 30-35% of EGPA patients. MPO-ANCA should be tested with antigen-specific immunoassays in any...

A federated AI strategy for the classification of patients with Mucosa Associated Lymphoma Tissue (MALT) lymphoma across multiple harmonized cohorts.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Pezoulas VC, Kalatzis F, Exarchos TP, Chatzis L, Gandolfo S, Goules A, De Vita S, Tzioufas AG, Fotiadis DI.
PMID: 34891605
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:1666-1669. doi: 10.1109/EMBC46164.2021.9630014.

Mucosa Associated Lymphoma Tissue (MALT) type is an extremely rare type of lymphoma which occurs in less than 3% of patients with primary Sjögren's Syndrome (pSS). No reported studies so far have been able to investigate risk factors for...

A computational workflow for the detection of candidate diagnostic biomarkers of Kawasaki disease using time-series gene expression data.

Computational and structural biotechnology journal

Pezoulas VC, Papaloukas C, Veyssiere M, Goules A, Tzioufas AG, Soumelis V, Fotiadis DI.
PMID: 34136104
Comput Struct Biotechnol J. 2021 May 24;19:3058-3068. doi: 10.1016/j.csbj.2021.05.036. eCollection 2021.

Unlike autoimmune diseases, there is no known constitutive and disease-defining biomarker for systemic autoinflammatory diseases (SAIDs). Kawasaki disease (KD) is one of the "undiagnosed" types of SAIDs whose pathogenic mechanism and gene mutation still remain unknown. To address this...

COVID-19 Immunobiology: Lessons Learned, New Questions Arise.

Frontiers in immunology

Kaklamanos A, Belogiannis K, Skendros P, Gorgoulis VG, Vlachoyiannopoulos PG, Tzioufas AG.
PMID: 34512643
Front Immunol. 2021 Aug 26;12:719023. doi: 10.3389/fimmu.2021.719023. eCollection 2021.

There is strong evidence that COVID-19 pathophysiology is mainly driven by a spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from asymptomatic to severe disease/death, and its associated mortality, are dictated by and linked to maladaptive innate and adaptive...

The clinical and technical impact of the HarmonicSS project.

Clinical and experimental rheumatology

Goules AV, Exarchos TP, Fotiadis DI, Tzioufas A.
PMID: 34596036
Clin Exp Rheumatol. 2021 Nov-Dec;39(6):17-19. Epub 2021 Sep 21.

No abstract available.

DNA Methylation Studies in Saliva of Patients with Sjögren's Syndrome.

Mediterranean journal of rheumatology

Karagianni P, Kapsogeorgou EK, Tzioufas AG, Goules AV.
PMID: 34447917
Mediterr J Rheumatol. 2021 Jun 30;32(2):176-178. doi: 10.31138/mjr.32.2.176. eCollection 2021 Jun.

Sjögren's syndrome (SS) is a relatively common systemic autoimmune disease of unknown aetiology, although genetic, hormonal, immunologic, and environmental factors are thought to be involved in disease pathogenesis. It is also termed "autoimmune epithelitis", and afflicts mainly the epithelial...

Machine Learning Approaches on High Throughput NGS Data to Unveil Mechanisms of Function in Biology and Disease.

Cancer genomics & proteomics

Pezoulas VC, Hazapis O, Lagopati N, Exarchos TP, Goules AV, Tzioufas AG, Fotiadis DI, Stratis IG, Yannacopoulos AN, Gorgoulis VG.
PMID: 34479914
Cancer Genomics Proteomics. 2021 Sep-Oct;18(5):605-626. doi: 10.21873/cgp.20284.

In this review, the fundamental basis of machine learning (ML) and data mining (DM) are summarized together with the techniques for distilling knowledge from state-of-the-art omics experiments. This includes an introduction to the basic mathematical principles of unsupervised/supervised learning...

Role of miR200b-5p miRNA in lymphomagenesis associated with Sjögren's syndrome (SS).

Mediterranean journal of rheumatology

Kapsogeorgou EK, Tzioufas AG.
PMID: 32185300
Mediterr J Rheumatol. 2018 Mar 19;29(1):56-58. doi: 10.31138/mjr.29.1.56. eCollection 2018 Mar.

BACKGROUND: Development of non-Hodgkin's lymphoma (NHL) is the major adverse outcome of primary Sjögren's Syndrome (pSS) affecting both morbidity and mortality. The high frequency of transformation to lymphoid malignancy in pSS among autoimmune rheumatic diseases (6-10% of patients) and...

Salivary Gland Ultrasonography in Sjögren's Syndrome: A European Multicenter Reliability Exercise for the HarmonicSS Project.

Frontiers in medicine

Zabotti A, Zandonella Callegher S, Tullio A, Vukicevic A, Hocevar A, Milic V, Cafaro G, Carotti M, Delli K, De Lucia O, Ernst D, Ferro F, Gattamelata A, Germanò G, Giovannini I, Hammenfors D, Jonsson MV, Jousse-Joulin S, Macchioni P, Parisi S, Perricone C, Stradner MH, Filipovic N, Tzioufas AG, Valent F, De Vita S.
PMID: 33330537
Front Med (Lausanne). 2020 Nov 23;7:581248. doi: 10.3389/fmed.2020.581248. eCollection 2020.

No abstract available.

Showing 1 to 12 of 70 entries