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Showing 1 to 10 of 10 entries
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The TRAR gene classifier to predict response to neoadjuvant therapy in HER2-positive and ER-positive breast cancer patients: an explorative analysis from the NeoSphere trial.

Molecular oncology

Triulzi T, Bianchini G, Di Cosimo S, Pienkowski T, Im YH, Bianchi GV, Galbardi B, Dugo M, De Cecco L, Tseng LM, Liu MC, Bermejo B, Semiglazov V, Viale G, de la Haba-Rodriguez J, Oh DY, Poirier B, Valagussa P, Gianni L, Tagliabue E.
PMID: 34816585
Mol Oncol. 2021 Nov 23; doi: 10.1002/1878-0261.13141. Epub 2021 Nov 23.

As most erb-b2 receptor tyrosine kinase 2 (HER2)-positive breast cancer (BC) patients currently receive dual HER2-targeting added to neoadjuvant chemotherapy, improved methods for identifying individual response, and assisting postsurgical salvage therapy, are needed. Herein, we evaluated the 41-gene classifier...

The TRAR gene classifier to predict response to neoadjuvant therapy in HER2-positive and ER-positive breast cancer patients: an explorative analysis from the NeoSphere trial.

Molecular oncology

Triulzi T, Bianchini G, Di Cosimo S, Pienkowski T, Im YH, Valeria Bianchi G, Galbardi B, Dugo M, De Cecco L, Tseng LM, Liu MC, Bermejo B, Semiglazov V, Viale G, de la Haba-Rodriguez J, Oh DY, Poirier B, Valagussa P, Gianni L, Tagliabue E.
PMID: 34816585
Mol Oncol. 2021 Nov 23; doi: 10.1002/1878-0261.13141. Epub 2021 Nov 23.

As most erb-b2 receptor tyrosine kinase 2 (HER2)-positive breast cancer (BC) patients currently receive dual HER2-targeting added to neoadjuvant chemotherapy, improved methods for identifying individual response, and assisting post-surgical salvage therapy, are needed. Herein, we evaluated the 41-gene classifier...

Clinically useful measures to assess the effectiveness of treatments: hints for a proper choice with special emphasis on cancer research.

Tumori

Boracchi P, Mezzanotte G, Mariani L, Valagussa P, Marubini E.
PMID: 2321266
Tumori. 1990 Feb 28;76(1):1-9.

Several absolute and relative measures useful to assess the consequences of treatments in cancer research are presented together with statistical methods suitable for computing the pertinent confidence intervals. The relationship of these measures with the parameters of the regression...

The influential and inspirational Gianni Bonadonna's life commitment to evidence-based cancer medicine.

Annals of oncology : official journal of the European Society for Medical Oncology

Curigliano G, Valagussa P, Veronesi U, Gianni L.
PMID: 26598541
Ann Oncol. 2016 Jan;27(1):6-8. doi: 10.1093/annonc/mdv565. Epub 2015 Nov 23.

No abstract available.

Effects of neoadjuvant trastuzumab, pertuzumab and palbociclib on Ki67 in HER2 and ER-positive breast cancer.

NPJ breast cancer

Gianni L, Colleoni M, Bisagni G, Mansutti M, Zamagni C, Del Mastro L, Zambelli S, Bianchini G, Frassoldati A, Maffeis I, Valagussa P, Viale G.
PMID: 35013314
NPJ Breast Cancer. 2022 Jan 10;8(1):1. doi: 10.1038/s41523-021-00377-8.

The crosstalk between estrogen and HER2 receptors and cell-cycle regulation sustains resistance to endocrine therapy of HER2- and hormone receptor-positive breast cancer. We earlier reported that women with HER2 and ER-positive breast cancer receiving neoadjuvant dual HER2-block and palbociclib...

Sequential Adriamycin and CMF in Metastatic Breast Cancer.

The oncologist

Zambetti M, Giacobone A, Terenziani M, Zucchinelli P, Demicheli R, Biasi S, Piotti P, Bartoli C, Valagussa P, Bonadonna G.
PMID: 10388053
Oncologist. 1997;2(4):223-227.

PURPOSE: To evaluate the clinical activity of a sequential treatment with Adriamycin followed by CMF (cyclophosphamide, methotrexate, fluorouracil) and the relative therapeutic contribution of the two drug regimens given at full conventional doses in metastatic breast cancer. PATIENTS AND...

Physiological Profile Assessment of Posture in Children and Adolescents with Autism Spectrum Disorder and Typically Developing Peers.

Brain sciences

Perin C, Valagussa G, Mazzucchelli M, Gariboldi V, Cerri CG, Meroni R, Grossi E, Cornaggia CM, Menant J, Piscitelli D.
PMID: 32992546
Brain Sci. 2020 Sep 27;10(10). doi: 10.3390/brainsci10100681.

A sound postural system requires sensorimotor integration. Evidence suggests that individuals with Autism Spectrum Disorder (ASD) present sensorimotor integration impairments. The Physiological Profile Assessment (PPA) can be used to evaluate postural capacity assessing five physiological subsets (i.e., vision, reaction...

Relationship between tip-toe behavior and soleus - gastrocnemius muscle lengths in individuals with autism spectrum disorders.

Journal of orthopaedics

Valagussa G, Balatti V, Trentin L, Piscitelli D, Yamagata M, Grossi E.
PMID: 32982098
J Orthop. 2020 Aug 20;21:444-448. doi: 10.1016/j.jor.2020.08.013. eCollection 2020.

BACKGROUND: About 20% of individuals with autism spectrum disorders (ASD) showed tip-toe behavior (TTB). This behavior may be related to a decreased ankle joint range of motion (ROM) in dorsiflexion. Physiologically, gastrocnemius (GM) and soleus (SM) muscles influence ankle...

Patterns of Restricted and Repetitive Behaviors in Autism Spectrum Disorders: A Cross-Sectional Video Recording Study. Preliminary Report.

Brain sciences

Grossi E, Caminada E, Goffredo M, Vescovo B, Castrignano T, Piscitelli D, Valagussa G, Franceschini M, Vanzulli F.
PMID: 34064245
Brain Sci. 2021 May 21;11(6). doi: 10.3390/brainsci11060678.

BACKGROUND: Several instruments have been proposed to investigate restricted, repetitive behaviors (RRBs) in individuals with Autism Spectrum Disorder (ASD). Systematic video observations may overcome questionnaire and interview limitations to investigate RRBs. This study aimed to analyze stereotypic patterns through...

Role of landslides on the volume balance of the Nepal 2015 earthquake sequence.

Scientific reports

Valagussa A, Frattini P, Valbuzzi E, Crosta GB.
PMID: 33564079
Sci Rep. 2021 Feb 09;11(1):3434. doi: 10.1038/s41598-021-83037-y.

The 7.8 M

Showing 1 to 10 of 10 entries