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Showing 1 to 12 of 101 entries
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Gene-environment interaction research and transgenic mouse models of Alzheimer's disease.

International journal of Alzheimer's disease

Chouliaras L, Sierksma AS, Kenis G, Prickaerts J, Lemmens MA, Brasnjevic I, van Donkelaar EL, Martinez-Martinez P, Losen M, De Baets MH, Kholod N, van Leeuwen F, Hof PR, van Os J, Steinbusch HW, van den Hove DL, Rutten BP.
PMID: 20953364
Int J Alzheimers Dis. 2010 Oct 05;2010. doi: 10.4061/2010/859101.

The etiology of the sporadic form of Alzheimer's disease (AD) remains largely unknown. Recent evidence has suggested that gene-environment interactions (GxE) may play a crucial role in its development and progression. Whereas various susceptibility loci have been identified, like...

Single-shot readout of an electron spin in silicon.

Nature

Morello A, Pla JJ, Zwanenburg FA, Chan KW, Tan KY, Huebl H, Möttönen M, Nugroho CD, Yang C, van Donkelaar JA, Alves AD, Jamieson DN, Escott CC, Hollenberg LC, Clark RG, Dzurak AS.
PMID: 20877281
Nature. 2010 Oct 07;467(7316):687-91. doi: 10.1038/nature09392. Epub 2010 Sep 26.

The size of silicon transistors used in microelectronic devices is shrinking to the level at which quantum effects become important. Although this presents a significant challenge for the further scaling of microprocessors, it provides the potential for radical innovations...

Erratum: gene-environment interaction research and transgenic mouse models of Alzheimer's disease.

International journal of Alzheimer's disease

Chouliaras L, Sierksma AS, Kenis G, Prickaerts J, Lemmens MA, Brasnjevic I, van Donkelaar EL, Martinez-Martinez P, Losen M, De Baets MH, Kholod N, van Leeuwen FW, Hof PR, van Os J, Steinbusch HW, van den Hove DL, Rutten BP.
PMID: 21318175
Int J Alzheimers Dis. 2011 Jan 10;2010:356862. doi: 10.4061/2010/356862.

No abstract available.

Pleiotropic Contribution of .

Frontiers in behavioral neuroscience

van Donkelaar MMJ, Hoogman M, Pappa I, Tiemeier H, Buitelaar JK, Franke B, Bralten J.
PMID: 29666571
Front Behav Neurosci. 2018 Apr 03;12:61. doi: 10.3389/fnbeh.2018.00061. eCollection 2018.

Reactive and proactive subtypes of aggression have been recognized to help parse etiological heterogeneity of this complex phenotype. With a heritability of about 50%, genetic factors play a role in the development of aggressive behavior. Imaging studies implicate brain...

Sport-Related Concussion Alters Indices of Dynamic Cerebral Autoregulation.

Frontiers in neurology

Wright AD, Smirl JD, Bryk K, Fraser S, Jakovac M, van Donkelaar P.
PMID: 29636724
Front Neurol. 2018 Mar 27;9:196. doi: 10.3389/fneur.2018.00196. eCollection 2018.

Sport-related concussion is known to affect a variety of brain functions. However, the impact of this brain injury on cerebral autoregulation (CA) is poorly understood. Thus, the goal of the current study was to determine the acute and cumulative...

Transient climate and ambient health impacts due to national solid fuel cookstove emissions.

Proceedings of the National Academy of Sciences of the United States of America

Lacey FG, Henze DK, Lee CJ, van Donkelaar A, Martin RV.
PMID: 28115698
Proc Natl Acad Sci U S A. 2017 Feb 07;114(6):1269-1274. doi: 10.1073/pnas.1612430114. Epub 2017 Jan 23.

Residential solid fuel use contributes to degraded indoor and ambient air quality and may affect global surface temperature. However, the potential for national-scale cookstove intervention programs to mitigate the latter issues is not yet well known, owing to the...

Effect modification of perinatal exposure to air pollution and childhood asthma incidence.

The European respiratory journal

Lavigne É, Bélair MA, Rodriguez Duque D, Do MT, Stieb DM, Hystad P, van Donkelaar A, Martin RV, Crouse DL, Crighton E, Chen H, Burnett RT, Weichenthal S, Villeneuve PJ, To T, Brook JR, Johnson M, Cakmak S, Yasseen AS, Walker M.
PMID: 29419440
Eur Respir J. 2018 Feb 01; doi: 10.1183/13993003.01884-2017. Epub 2018 Feb 01.

Perinatal exposure to ambient air pollution has been associated with childhood asthma incidence, however, less is known regarding the potential effect modifiers in this association. We examined whether maternal and infant characteristics modified the association between perinatal exposure to...

Estimating Intra-Urban Inequities in PM.

GeoHealth

Castillo MD, Kinney PL, Southerland V, Arno CA, Crawford K, van Donkelaar A, Hammer M, Martin RV, Anenberg SC.
PMID: 34765851
Geohealth. 2021 Nov 01;5(11):e2021GH000431. doi: 10.1029/2021GH000431. eCollection 2021 Nov.

Air pollution levels are uneven within cities, contributing to persistent health disparities between neighborhoods and population sub-groups. Highly spatially resolved information on pollution levels and disease rates is necessary to characterize inequities in air pollution exposure and related health...

Maternal exposure to fine particulate matter and preterm birth and low birth weight in Africa.

Environment international

Bachwenkizi J, Liu C, Meng X, Zhang L, Wang W, van Donkelaar A, Martin RV, Hammer MS, Chen R, Kan H.
PMID: 34942408
Environ Int. 2021 Dec 20;160:107053. doi: 10.1016/j.envint.2021.107053. Epub 2021 Dec 20.

BACKGROUND: Fine particulate matter (PMMETHODS: We used standard Demographic and Health Surveys (DHS) data (2005-2015) from 15 countries in Africa to conduct a cross-sectional study. The study population was composed of 131,594 births with detailed information on maternal and...

Local variations in mechanical properties of human hamstring tendon autografts for anterior cruciate ligament reconstruction do not translate to a mechanically inferior strand.

Journal of the mechanical behavior of biomedical materials

van Vijven M, van Groningen B, Janssen RPA, van der Steen MC, van Doeselaar M, Stefanoska D, van Donkelaar CC, Ito K, Foolen J.
PMID: 34896765
J Mech Behav Biomed Mater. 2021 Dec 03;126:105010. doi: 10.1016/j.jmbbm.2021.105010. Epub 2021 Dec 03.

A ruptured anterior cruciate ligament (ACL) is often reconstructed with a multiple-strand autograft of a semitendinosus tendon alone or combined with a gracilis tendon. Up to 10% of patients experience graft rupture. This potentially results from excessive local tissue...

Long-term exposure to PM.

Environment international

Wang Y, Xiao S, Zhang Y, Chang H, Martin RV, Van Donkelaar A, Gaskins A, Liu Y, Liu P, Shi L.
PMID: 34741960
Environ Int. 2022 Jan;158:106969. doi: 10.1016/j.envint.2021.106969. Epub 2021 Nov 04.

BACKGROUND: Long-term exposure to fine particulate matter (PMMETHODS: We conducted a population-based cohort study, comprising all Medicare enrollees aged 65 or older in the southeastern United States from 2000 to 2016, to explore the associations between long-term exposure to...

Proteoglycan 4 reduces friction more than other synovial fluid components for both cartilage-cartilage and cartilage-metal articulation.

Osteoarthritis and cartilage

Damen AHA, van Donkelaar CC, Cardinaels RM, Brandt JM, Schmidt TA, Ito K.
PMID: 33647390
Osteoarthritis Cartilage. 2021 Jun;29(6):894-904. doi: 10.1016/j.joca.2021.02.566. Epub 2021 Feb 27.

OBJECTIVE: The clinical success of focal metallic resurfacing implants depends largely on the friction between implant and opposing cartilage. Therefore, the present study determines the lubricating ability of the synovial fluid components hyaluronic acid (HA), proteoglycan 4 (PRG4) and...

Showing 1 to 12 of 101 entries