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Showing 1 to 12 of 116 entries
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Epigenetic control of HIV-1 post integration latency: implications for therapy.

Clinical epigenetics

Kumar A, Darcis G, Van Lint C, Herbein G.
PMID: 26405463
Clin Epigenetics. 2015 Sep 24;7:103. doi: 10.1186/s13148-015-0137-6. eCollection 2015.

With the development of effective combined anti-retroviral therapy (cART), there is significant reduction in deaths associated with human immunodeficiency virus type 1 (HIV-1) infection. However, the complete cure of HIV-1 infection is difficult to achieve without the elimination of...

Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage.

Genome announcements

Bart MJ, van der Heide HG, Zeddeman A, Heuvelman K, van Gent M, Mooi FR.
PMID: 26607899
Genome Announc. 2015 Nov 25;3(6). doi: 10.1128/genomeA.01394-15.

Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do...

Stereo- and regiospecific cu-catalyzed cross-coupling reaction of vinyl iodides and thiols: a very mild and general route for the synthesis of vinyl sulfides.

Organic letters

Kabir MS, Van Linn ML, Monte A, Cook JM.
PMID: 18611035
Org Lett. 2008 Aug 07;10(15):3363-6. doi: 10.1021/ol801149n. Epub 2008 Jul 09.

A mild and efficient method for the copper-catalyzed formation of vinylic carbon-sulfur bonds has been developed. The desired vinyl sulfides are obtained in good to excellent yields, with full retention of stereochemistry. This method is particularly noteworthy given its...

Cowpea mosaic virus: effects on host cell processes.

Molecular plant pathology

Pouwels J, Carette JE, Van Lent J, Wellink J.
PMID: 20569348
Mol Plant Pathol. 2002 Nov 01;3(6):411-8. doi: 10.1046/j.1364-3703.2002.00135.x.

SUMMARY Taxonomy: Cowpea mosaic virus (CPMV) is the type member of the Comoviridae and bears a strong resemblance to animal picornaviruses, both in gene organization and in the amino acid sequence of replication proteins. Little systematic work has been...

Strength of patient cohorts and biobanks for cardiomyopathy research.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

de Boer RA, Nijenkamp LLAM, Silljé HHW, Eijgenraam TR, Parbhudayal R, van Driel B, Huurman R, Michels M, Pei J, Harakalova M, van Lint FHM, Jansen M, Baas AF, Asselbergs FW, van Tintelen JP, Brundel BJJM, Dorsch LM, Schuldt M, Kuster DWD, van der Velden J.
PMID: 32780332
Neth Heart J. 2020 Aug;28:50-56. doi: 10.1007/s12471-020-01456-4.

In 2011 the Netherlands Heart Foundation allocated funding (CVON, Cardiovasculair Onderzoek Nederland) to stimulate collaboration between clinical and preclinical researchers on specific areas of research. One of those areas involves genetic heart diseases, which are frequently caused by pathogenic...

Anti-Xa Levels in Morbidly Obese Patients Using Apixaban or Rivaroxaban, Before and After Bariatric Surgery.

Obesity surgery

Kok T, de Boer H, Witteman B, Hovens M, van Luin M, Monajemi H.
PMID: 34822108
Obes Surg. 2021 Nov 25; doi: 10.1007/s11695-021-05814-y. Epub 2021 Nov 25.

BACKGROUND: Despite limited evidence about the efficacy and safety of anticoagulation in patients post bariatric surgery, both vitamin K antagonists (VKA) and direct-acting oral anticoagulants (DOACs) are commonly prescribed.AIM: To evaluate plasma anti-Xa levels of DOACs in morbidly obese...

Development and psychometric evaluation of a Positive Health measurement scale: a factor analysis study based on a Dutch population.

BMJ open

Van Vliet M, Doornenbal BM, Boerema S, van den Akker-van Marle EM.
PMID: 33550237
BMJ Open. 2021 Feb 05;11(2):e040816. doi: 10.1136/bmjopen-2020-040816.

OBJECTIVES: The My Positive Health (MPH) dialogue tool is increasingly adopted by healthcare professionals in the Netherlands as well as abroad to support people in their health. Given this trend, the need arises to measure effects of interventions on...

Measuring positive health: Concurrent and factorial validity based on a representative Dutch sample.

Health & social care in the community

Doornenbal BM, Vos RC, Van Vliet M, Kiefte-De Jong JC, van den Akker-van Marle ME.
PMID: 34791738
Health Soc Care Community. 2021 Nov 18; doi: 10.1111/hsc.13649. Epub 2021 Nov 18.

The definition of health has been shifting from disease absence to physical, emotional and social well-being. To demedicalise societal problems, the term Positive Health (PH) was introduced-a concept focused on the ability to adapt and to self-manage, in the...

The neural representation of abstract words may arise through grounding word meaning in language itself.

Human brain mapping

Hultén A, van Vliet M, Kivisaari S, Lammi L, Lindh-Knuutila T, Faisal A, Salmelin R.
PMID: 34264550
Hum Brain Mapp. 2021 Oct 15;42(15):4973-4984. doi: 10.1002/hbm.25593. Epub 2021 Jul 15.

In order to describe how humans represent meaning in the brain, one must be able to account for not just concrete words but, critically, also abstract words, which lack a physical referent. Hebbian formalism and optimization are basic principles...

The effects of antidiabetic agents on heart failure.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Wijnen M, Duschek EJJ, Boom H, van Vliet M.
PMID: 34097240
Neth Heart J. 2021 Jun 07; doi: 10.1007/s12471-021-01579-2. Epub 2021 Jun 07.

In the Netherlands, approximately 250,000 people are living with heart failure. About one-third of them have comorbid diabetes mellitus type 2. Until recently, the effects of antidiabetic agents on heart failure were largely unknown. This changed after an observed...

Dose Reduction in Coronary Artery Calcium Scoring Using Mono-Energetic Images from Reduced Tube Voltage Dual-Source Photon-Counting CT Data: A Dynamic Phantom Study.

Diagnostics (Basel, Switzerland)

van der Werf NR, van Gent M, Booij R, Bos D, van der Lugt A, Budde RPJ, Greuter MJW, van Straten M.
PMID: 34943428
Diagnostics (Basel). 2021 Nov 25;11(12). doi: 10.3390/diagnostics11122192.

In order to assess coronary artery calcium (CAC) quantification reproducibility for photon-counting computed tomography (PCCT) at reduced tube potential, an anthropomorphic thorax phantom with low-, medium-, and high-density CAC inserts was scanned with PCCT (NAEOTOM Alpha, Siemens Healthineers) at...

Long-Read Sequencing to Unravel Complex Structural Variants of .

Frontiers in cell and developmental biology

Ascari G, Rendtorff ND, De Bruyne M, De Zaeytijd J, Van Lint M, Bauwens M, Van Heetvelde M, Arno G, Jacob J, Creytens D, Van Dorpe J, Van Laethem T, Rosseel T, De Pooter T, De Rijk P, De Coster W, Menten B, Rey AD, Strazisar M, Bertelsen M, Tranebjaerg L, De Baere E.
PMID: 33968938
Front Cell Dev Biol. 2021 Apr 21;9:664317. doi: 10.3389/fcell.2021.664317. eCollection 2021.

Inactivating variants as well as a missense variant in the centrosomal

Showing 1 to 12 of 116 entries