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Showing 1 to 12 of 56 entries
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Phase II study of vincristine, bleomycin, mitomycin C and cisplatin (VBMP) in disseminated squamous cell carcinoma of the uterine cervix.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Vermorken JB, Mangioni C, Pecorelli S, Van Der Burg ME, Van Oosterom AT, Ten Bokkel Huinink WW, Rotmensz N, Dalesio O.
PMID: 11240699
Int J Gynecol Cancer. 2000 Sep;10(5):358-365. doi: 10.1046/j.1525-1438.2000.010005358.x.

The objective of this study was to study the antitumor activity of the vincristine, bleomycin, mitomycin C and cisplatin (VBMP) scheme in patients with disseminated squamous cell carcinoma of the uterine cervix and to document its toxicity. VBMP consisted...

The number of signals in multilead ECGs in individuals.

Journal of electrocardiology

Uijen GJ, van Oosterom A.
PMID: 8501406
J Electrocardiol. 1993 Apr;26(2):107-16. doi: 10.1016/0022-0736(93)90002-u.

The number of independent signals in multilead electrocardiograms (ECGs) (body surface maps) of individuals have been determined by using two different methods. Both methods are based on an analysis of the eigenvalues of the spatial covariance matrix corresponding to...

Click Chemistry in the Design and Production of Hybrid Tracers.

ACS omega

Hensbergen AW, van Willigen DM, Welling MM, van der Wijk FA, de Korne CM, van Oosterom MN, Schottelius M, Wester HJ, Buckle T, van Leeuwen FWB.
PMID: 31460363
ACS Omega. 2019 Jul 22;4(7):12438-12448. doi: 10.1021/acsomega.9b01484. eCollection 2019 Jul 31.

Hybrid tracers containing both fluorescent and radioactive imaging labels have demonstrated clinical potential during sentinel lymph node procedures. To combine these two labels on a single targeting vector that allows tumor-targeted imaging, end-labeling strategies are often applied. For α

Potential yield and water-use efficiency benefits in sorghum from limited maximum transpiration rate.

Functional plant biology : FPB

Sinclair TR, Hammer GL, van Oosterom EJ.
PMID: 32689190
Funct Plant Biol. 2005 Oct;32(10):945-952. doi: 10.1071/FP05047.

Limitations on maximum transpiration rates, which are commonly observed as midday stomatal closure, have been observed even under well-watered conditions. Such limitations may be caused by restricted hydraulic conductance in the plant or by limited supply of water to...

Childhood trauma and negative memory bias as shared risk factors for psychopathology and comorbidity in a naturalistic psychiatric patient sample.

Brain and behavior

Vrijsen JN, van Amen CT, Koekkoek B, van Oostrom I, Schene AH, Tendolkar I.
PMID: 30585448
Brain Behav. 2018 Dec;8(12):e01181. doi: 10.1002/brb3.1181.

No abstract available.

Optical Navigation of the Drop-In γ-Probe as a Means to Strengthen the Connection Between Robot-Assisted and Radioguided Surgery.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Azargoshasb S, Houwing KHM, Roos PR, van Leeuwen SI, Boonekamp M, Mazzone E, Bauwens K, Dell'Oglio P, van Leeuwen FWB, van Oosterom MN.
PMID: 33419942
J Nucl Med. 2021 Sep 01;62(9):1314-1317. doi: 10.2967/jnumed.120.259796. Epub 2021 Jan 08.

With translation of the Drop-In γ-probe, radioguidance has advanced into laparoscopic robot-assisted surgery. Global-positioning-system-like navigation can further enhance the symbiosis between nuclear medicine and surgery. Therefore, we developed a fluorescence-video-based tracking method that integrates the Drop-In with navigated robotic...

Manipulating assimilate availability provides insight into the genes controlling grain size in sorghum.

The Plant journal : for cell and molecular biology

Tao Y, Trusov Y, Zhao X, Wang X, Cruickshank AW, Hunt C, van Oosterom EJ, Hathorn A, Liu G, Godwin ID, Botella JR, Mace ES, Jordan DR.
PMID: 34309934
Plant J. 2021 Oct;108(1):231-243. doi: 10.1111/tpj.15437. Epub 2021 Aug 13.

Variation in grain size, a major determinant of grain yield and quality in cereal crops, is determined by both the plant's genetic potential and the available assimilate to fill the grain in the absence of stress. This study investigated...

Assessing the value of volume navigation during ultrasound-guided radiofrequency- and microwave-ablations of liver lesions.

European journal of radiology open

Meershoek P, van den Berg NS, Lutjeboer J, Burgmans MC, van der Meer RW, van Rijswijk CSP, van Oosterom MN, van Erkel AR, van Leeuwen FWB.
PMID: 34286051
Eur J Radiol Open. 2021 Jul 08;8:100367. doi: 10.1016/j.ejro.2021.100367. eCollection 2021.

PURPOSE: The goal of our study was to determine the influence of ultrasound (US)-coupled volume navigation on the use of computed tomography (CT) during minimally-invasive radiofrequency and microwave ablation procedures of liver lesions.METHOD: Twenty-five patients with 40 liver lesions...

Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach.

Toxicology

Fragki S, Hoogenveen R, van Oostrom C, Schwillens P, Piersma AH, Zeilmaker MJ.
PMID: 34871708
Toxicology. 2021 Dec 04;465:153060. doi: 10.1016/j.tox.2021.153060. Epub 2021 Dec 04.

With the increasing application of cell culture models as primary tools for predicting chemical safety, the quantitative extrapolation of the effective dose from in vitro to in vivo (QIVIVE) is of increasing importance. For developmental toxicity this requires scaling...

Optical Navigation of the Drop-In γ-Probe as a Means to Strengthen the Connection Between Robot-Assisted and Radioguided Surgery.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Azargoshasb S, Houwing KHM, Roos PR, van Leeuwen SI, Boonekamp M, Mazzone E, Bauwens K, Dell'Oglio P, van Leeuwen FWB, van Oosterom MN.
PMID: 33419942
J Nucl Med. 2021 Sep 01;62(9):1314-1317. doi: 10.2967/jnumed.120.259796. Epub 2021 Jan 08.

With translation of the Drop-In γ-probe, radioguidance has advanced into laparoscopic robot-assisted surgery. Global-positioning-system-like navigation can further enhance the symbiosis between nuclear medicine and surgery. Therefore, we developed a fluorescence-video-based tracking method that integrates the Drop-In with navigated robotic...

c-MET receptor-targeted fluorescence on the road to image-guided surgery in penile squamous cell carcinoma patients.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

de Vries HM, Bekers E, van Oosterom MN, Krakullukcu MB, van der Poel HG, van Leeuwen FWB, Buckle T, Brouwer OR.
PMID: 33990404
J Nucl Med. 2021 May 14; doi: 10.2967/jnumed.120.261864. Epub 2021 May 14.

In penile squamous cell carcinoma (pSCC), primary surgery aims to obtain oncologically safe margins while minimizing mutilation. Surgical guidance provided by receptor-specific tracers could potentially improve margin detection and reduce unnecessary excision of healthy tissue. Here, we present the...

Platelet function assays for the diagnosis of aspirin resistance.

Platelets

Van Oosterom N, Barras M, Cottrell N, Bird R.
PMID: 34166171
Platelets. 2021 Jun 24;1-10. doi: 10.1080/09537104.2021.1942816. Epub 2021 Jun 24.

Aspirin, an antiplatelet drug, is commonly used at low doses for numerous indications, including prophylaxis of cardiovascular, neurovascular, and venous thromboembolic events. Due to review articles suggesting that aspirin resistance may result in poorer outcomes, interest in assessing platelet...

Showing 1 to 12 of 56 entries