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Showing 1 to 12 of 23 entries
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Hair-Normalized Cortisol Waking Response as a Novel Biomarker of Hypothalamic-Pituitary-Adrenal Axis Activity following Acute Trauma: A Proof-of-Concept Study with Pilot Results.

Pain research and treatment

Walton DM, Macdermid JC, Russell E, Koren G, Van Uum S.
PMID: 24367724
Pain Res Treat. 2013;2013:876871. doi: 10.1155/2013/876871. Epub 2013 Dec 03.

The mechanisms underlying the development of persistent posttraumatic pain and disability remain elusive. Recent evidence suggests that disordered stress-system pathway (hypothalamic-pituitary-adrenal axis) activity may be responsible for the genesis and maintenance of long-term sensory and emotional problems. However, confidence...

High aldosterone, hypertension and adrenal adenoma in a 36-year-old pregnant patient: Is this primary aldosteronism?.

Obstetric medicine

Berberich AJ, Penava D, Sun D, MacDougall A, Lum A, Van Uum S.
PMID: 32714441
Obstet Med. 2020 Jun;13(2):88-91. doi: 10.1177/1753495X18786422. Epub 2018 Nov 04.

A 36-year-old woman presented at 16 weeks' gestation with severe hypertension. In comparison to the non-pregnant reference normal ranges, potassium was 3.1-3.9 mmol/L, aldosterone 2570-3000 pmol/L (N 250-2885) renin was unsuppressed (24-76.4 ng/L (N1.7-23.9)), with aldosterone to renin ratios...

Contemporary Trends of Systemic Neoadjuvant and Adjuvant Intravesical Chemotherapy in Patients With Upper Tract Urothelial Carcinomas Undergoing Minimally Invasive or Open Radical Nephroureterectomy: Analysis of US Claims on Perioperative Outcomes and Health Care Costs.

Clinical genitourinary cancer

Del Giudice F, van Uem S, Li S, Vilson FL, Sciarra A, Salciccia S, Busetto GM, Maggi M, Tiberia L, Viscuso P, Canale V, Panebianco V, Pecoraro M, Ferro M, Moschini M, Krajewski W, D'Andrea D, Cacciamani GE, Mari A, Soria F, Porpiglia F, Fiori C, Amparore D, Checcucci E, Autorino R, De Berardinis E, Chung BI.
PMID: 35031226
Clin Genitourin Cancer. 2021 Dec 24; doi: 10.1016/j.clgc.2021.11.016. Epub 2021 Dec 24.

INTRODUCTION: New evidence indicates that minimally invasive surgery (MIS) (laparoscopic or robotic-assisted [LNU, RANU]) reaches oncologic equivalence compared with Open Radical Nephroureterectomy (ORNU) for high-risk upper-tract urothelial carcinoma (UTUC). Recently, European Association of Urology (EAU) Guidelines suggested implementing neoadjuvant...

Consensus recommendations for the diagnosis and management of well-differentiated gastroenterohepatic neuroendocrine tumours: a revised statement from a Canadian National Expert Group.

Current oncology (Toronto, Ont.)

Kocha W, Maroun J, Kennecke H, Law C, Metrakos P, Ouellet JF, Reid R, Rowsell C, Shah A, Singh S, Van Uum S, Wong R.
PMID: 20567626
Curr Oncol. 2010 Jun;17(3):49-64. doi: 10.3747/co.v17i3.484.

Well-differentiated neuroendocrine tumours (nets-previously called "carcinoid tumours") are relatively rare tumours originating from the diffuse neuroendocrine system; they are found most often in the bronchial or gastrointestinal systems. In Canada, gastroenterohepatic NETS represent less than 0.25% of oncology cases....

Familial papillary thyroid carcinoma: a retrospective analysis.

Journal of oncology

McDonald TJ, Driedger AA, Garcia BM, Van Uum SH, Rachinsky I, Chevendra V, Breadner D, Feinn R, Walsh SJ, Malchoff CD.
PMID: 22131992
J Oncol. 2011;2011:948786. doi: 10.1155/2011/948786. Epub 2011 Oct 25.

Background. Whether or not the familial form of papillary thyroid carcinoma is more aggressive than the sporadic form of the disease remains controversial. Methods. To explore this question and whether or not increased aggressiveness is more apparent in families...

Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease.

Neuropsychiatric disease and treatment

Dowlati Y, Herrmann N, Swardfager W, Thomson S, Oh PI, Van Uum S, Koren G, Lanctôt KL.
PMID: 20856603
Neuropsychiatr Dis Treat. 2010 Sep 07;6:393-400.

OBJECTIVE: Concentrations of cortisol in hair, a novel marker of longer-term cortisol status, were compared in depressed versus nondepressed patients with coronary artery disease (CAD).METHODS: 20 mg hair samples of 3 cm length were collected from 121 patients attending...

Effect of omalizumab for autoimmune progesterone dermatitis refractory to bilateral oophorectomy: a case report.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

Varghese A, Paul T, Kim H, Van Uum S, Vadas P, Azzola A.
PMID: 34120629
Allergy Asthma Clin Immunol. 2021 Jun 13;17(1):58. doi: 10.1186/s13223-021-00561-2.

BACKGROUND: Autoimmune progesterone dermatitis (APD) is a rare skin condition caused by sensitivity to high levels of progesterone secreted during the luteal phase of the menstrual cycle. This may be due to various pathophysiological mechanisms including a Type I...

Adrenal Cushing Syndrome Diagnosed During Pregnancy: Successful Medical Management With Metyrapone.

Journal of the Endocrine Society

Azzola A, Eastabrook G, Matsui D, Berberich A, Tirona RG, Gray D, Gallego P, Van Uum S.
PMID: 33305159
J Endocr Soc. 2020 Nov 05;5(1):bvaa167. doi: 10.1210/jendso/bvaa167. eCollection 2021 Jan 01.

Adrenal Cushing syndrome during pregnancy is rare, and there is limited information on the effect and safety of metyrapone treatment both for mother and fetus. We present a 24-year-old woman diagnosed with adrenal Cushing syndrome at the end of...

Prospective risk analysis adjusted to the reality of clinical and fertility laboratory processes.

Diagnosis (Berlin, Germany)

Janssens PMW, Scholten A, Waard H, Tiemens N, Van Uum M, Schrijver E, Roozenburg B, Verhaagen R, Harmsen S, Rabeling J, Katz E, Lentink B, Keijzer H, Van Welt E.
PMID: 29540040
Diagnosis (Berl). 2015 Dec 01;2(4):235-243. doi: 10.1515/dx-2015-0027.

BACKGROUND: Prospective risk analysis (PRA) is a valuable instrument in quality assurance. The practical application of PRA in clinical laboratories according to the method we have described elsewhere leaves room for a number of adaptations to make it more...

Pain management in acute otitis media: a qualitative study exploring GPs' views and expectations parallel to a trial of an educational intervention.

BJGP open

van Uum RT, Sjoukes A, Venekamp RP, Schilder AG, de Groot E, Damoiseaux RA, Anthierens S.
PMID: 30723805
BJGP Open. 2018 Oct 31;2(4):bjgpopen18X101620. doi: 10.3399/bjgpopen18X101620. eCollection 2018 Dec.

BACKGROUND: Optimal pain management is accepted as the cornerstone of acute otitis media (AOM) management, but analgesics are neither prescribed routinely nor explicitly recommended in day-to-day practice.AIM: To explore GPs views on and expectations regarding pain management in children...

Standards of care for hypoparathyroidism in adults: a Canadian and International Consensus.

European journal of endocrinology

Khan AA, Koch CA, Van Uum S, Baillargeon JP, Bollerslev J, Brandi ML, Marcocci C, Rejnmark L, Rizzoli R, Shrayyef MZ, Thakker R, Yildiz BO, Clarke B.
PMID: 30540559
Eur J Endocrinol. 2019 Mar;180(3):P1-P22. doi: 10.1530/EJE-18-0609.

PURPOSE: To provide practice recommendations for the diagnosis and management of hypoparathyroidism in adults.METHODS: Key questions pertaining to the diagnosis and management of hypoparathyroidism were addressed following a literature review. We searched PubMed, MEDLINE, EMBASE and Cochrane databases from...

Integrating cortisol and isotopic analyses of archaeological hair: Elucidating juvenile ante-mortem stress and behaviour.

International journal of paleopathology

Webb EC, White CD, Van Uum S, Longstaffe FJ.
PMID: 29539438
Int J Paleopathol. 2015 Jun;9:28-37. doi: 10.1016/j.ijpp.2014.12.001. Epub 2014 Dec 30.

Understanding childhood experiences of health and well-being is essential to reconstructing ancient life-ways. Here, archaeological hair samples from five juveniles from Cahuachi and near Huaca del Loro in the Nasca Region, Peru, are analyzed for their carbon- and nitrogen-isotope...

Showing 1 to 12 of 23 entries