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Duchenne Regulatory Science Consortium Meeting on Disease Progression Modeling for Duchenne Muscular Dystrophy.

PLoS currents

Larkindale J, Abresch R, Aviles E, Bronson A, Chin J, Furlong P, Gordish-Dressman H, Habeeb-Louks E, Henricson E, Kroger H, Lynn C, Lynn S, Martin D, Nuckolls G, Rooney W, Romero K, Sweeney L, Vandenborne K, Walter G, Wolff J, Wong B, McDonald CM, Duchenne Regulatory Science Consortium Imaging-Dmd Consortium And The Cinrg Investigators MO.
PMID: 28228973
PLoS Curr. 2017 Jan 12;9. doi: 10.1371/currents.md.83071bbd728982f2f1073f4950e03586.

INTRODUCTION: The Duchenne Regulatory Science Consortium (D-RSC) was established to develop tools to accelerate drug development for DMD.  The resulting tools are anticipated to meet validity requirements outlined by qualification/endorsement pathways at both the U.S. Food and Drug Administration...

Influence of Nitric Acid on the Helium Ion Radiolysis of Aqueous Butanal Oxime Solutions.

The journal of physical chemistry. A

Costagliola A, Venault L, Deroche A, Vermeulen J, Duval F, Blain G, Vandenborre J, Fattahi-Vanani M, Vigier N.
PMID: 28436222
J Phys Chem A. 2017 Jul 13;121(27):5069-5078. doi: 10.1021/acs.jpca.6b12630. Epub 2017 Jun 28.

Samples of butanal oxime in aqueous nitric acid solutions have been irradiated with the helium ion (

Leg muscle MRI in identical twin boys with duchenne muscular dystrophy.

Muscle & nerve

Willcocks RJ, Triplett WT, Lott DJ, Forbes SC, Batra A, Sweeney HL, Mendell JR, Vandenborne K, Walter GA.
PMID: 29365354
Muscle Nerve. 2018 Jan 24; doi: 10.1002/mus.26081. Epub 2018 Jan 24.

No abstract available.

Characterizing Expiratory Respiratory Muscle Degeneration in Duchenne Muscular Dystrophy Using MRI.

Chest

Barnard AM, Lott DJ, Batra A, Triplett WT, Willcocks RJ, Forbes SC, Rooney WD, Daniels MJ, Smith BK, Vandenborne K, Walter GA.
PMID: 34536384
Chest. 2021 Sep 15; doi: 10.1016/j.chest.2021.08.078. Epub 2021 Sep 15.

BACKGROUND: Expiratory muscle weakness and impaired airway clearance are early signs of respiratory dysfunction in Duchenne muscular dystrophy (DMD), a degenerative muscle disorder in which muscle cells are damaged and replaced by fibrofatty tissue. Little is known about expiratory...

Evaluating communication partner training in healthcare centres: Understanding the mechanisms of behaviour change.

International journal of language & communication disorders

van Rijssen M, Ketelaar M, Vandenborre D, Oostveen J, Veldkamp M, van Ewijk L, Visser-Meily JMA, Gerrits E.
PMID: 34370352
Int J Lang Commun Disord. 2021 Nov;56(6):1190-1203. doi: 10.1111/1460-6984.12659. Epub 2021 Aug 09.

BACKGROUND: Communication between people with aphasia and their healthcare professionals (HCPs) can be greatly improved when HCPs are trained in using supportive conversation techniques and tools. Communication partner training (CPT) is an umbrella term that covers a range of...

Molecular signatures of differential responses to exercise trainings during rehabilitation.

Biomedical genetics and genomics

Chen YW, Gregory C, Ye F, Harafuji N, Lott D, Lai SH, Mathur S, Scarborough M, Gibbs P, Baligand C, Vandenborne K.
PMID: 28845464
Biomed Genet Genom. 2017;2(1). doi: 10.15761/BGG.1000127. Epub 2017 Apr 10.

The loss and recovery of muscle mass and function following injury and during rehabilitation varies among individuals. While recent expression profiling studies have illustrated transcriptomic responses to muscle disuse and remodeling, how these changes contribute to the physiological responses...

A Database of Drug Repurposing Clinical Trials in Oncology.

Frontiers in pharmacology

Pantziarka P, Vandeborne L, Bouche G.
PMID: 34867425
Front Pharmacol. 2021 Nov 10;12:790952. doi: 10.3389/fphar.2021.790952. eCollection 2021.

No abstract available.

An Open Access Database of Licensed Cancer Drugs.

Frontiers in pharmacology

Pantziarka P, Capistrano I R, De Potter A, Vandeborne L, Bouche G.
PMID: 33776770
Front Pharmacol. 2021 Mar 11;12:627574. doi: 10.3389/fphar.2021.627574. eCollection 2021.

A global, comprehensive and open access listing of approved anticancer drugs does not currently exist. Partial information is available from multiple sources, including regulatory authorities, national formularies and scientific agencies. Many such data sources include drugs used in oncology...

A Systematic Review of Transcranial Direct Current Stimulation in Primary Progressive Aphasia: Methodological Considerations.

Frontiers in aging neuroscience

Coemans S, Struys E, Vandenborre D, Wilssens I, Engelborghs S, Paquier P, Tsapkini K, Keulen S.
PMID: 34690737
Front Aging Neurosci. 2021 Oct 07;13:710818. doi: 10.3389/fnagi.2021.710818. eCollection 2021.

A variety of tDCS approaches has been used to investigate the potential of tDCS to improve language outcomes, or slow down the decay of language competences caused by Primary Progressive Aphasia (PPA). The employed stimulation protocols and study designs...

Characterization of patients with Becker muscular dystrophy by histology, magnetic resonance imaging, function, and strength assessments.

Muscle & nerve

Comi GP, Niks EH, Cinnante CM, Kan HE, Vandenborne K, Willcocks RJ, Velardo D, Ripolone M, van Benthem JJ, van de Velde NM, Nava S, Ambrosoli L, Cazzaniga S, Bettica PU.
PMID: 34918368
Muscle Nerve. 2021 Dec 16; doi: 10.1002/mus.27475. Epub 2021 Dec 16.

INTRODUCTION/AIMS: Becker muscular dystrophy (BMD) is characterized by variable disease severity and progression, prompting the identification of biomarkers for clinical trials. We used data from an ongoing phase II study to provide a comprehensive characterization of a cohort of...

Sorption of uranyl cations on a rutile (001) single crystal monitored by surface second-harmonic generation.

Langmuir : the ACS journal of surfaces and colloids

Dossot M, Cremel S, Vandenborre J, Grausem J, Humbert B, Drot R, Simoni E.
PMID: 16378412
Langmuir. 2006 Jan 03;22(1):140-7. doi: 10.1021/la0519913.

The rotational anisotropy of second-harmonic generation at the surface of a (001) single-crystal rutile is obtained in the presence of uranyl cations sorbed at the surface from acidic solutions at various concentrations. Surface second-harmonic generation appears to be sensitive...

Texture Analysis for Muscular Dystrophy Classification in MRI with Improved Class Activation Mapping.

Pattern recognition

Cai J, Xing F, Batra A, Liu F, Walter GA, Vandenborne K, Yang L.
PMID: 31105339
Pattern Recognit. 2019 Feb;86:368-375. doi: 10.1016/j.patcog.2018.08.012. Epub 2018 Sep 18.

The muscular dystrophies are made up of a diverse group of rare genetic diseases characterized by progressive loss of muscle strength and muscle damage. Since there is no cure for muscular dystrophy and clinical outcome measures are limited, it...

Showing 1 to 12 of 20 entries