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Showing 1 to 12 of 31 entries
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Optimization of growth medium for protease production by Haloferax Lucentensis VKMM 007 by response surface methodology.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]

Manikandan M, Kannan V, Velikonja BH, Pašić L.
PMID: 24031697
Braz J Microbiol. 2011 Apr;42(2):818-24. doi: 10.1590/S1517-838220110002000050. Epub 2011 Jun 01.

The production of halophilic thermostable protease by Haloferax lucentensis VKMM 007 was optimized using a statistical approach. In accordance with factorial design, soluble starch, gelatin, KCl and MgSO4 were selected among 27 variables tested. Next, a second-order quadratic model...

Interleukin-18 serum level is elevated in type 2 diabetes and latent autoimmune diabetes.

Endocrine connections

Zaharieva E, Kamenov Z, Velikova T, Tsakova A, El-Darawish Y, Okamura H.
PMID: 29217651
Endocr Connect. 2018 Jan;7(1):179-185. doi: 10.1530/EC-17-0273. Epub 2017 Dec 07.

BACKGROUND: Interleukin-18 (IL-18) is an inflammatory cytokine found to be elevated in obesity, metabolic syndrome and type 2 diabetes (T2D) as a part of the chronic low-grade inflammatory process in these states. The aim of the study was to...

Identification of Specific IgE Antibodies and Asthma Control Interaction and Association Using Cluster Analysis in a Bulgarian Asthmatic Children Cohort.

Antibodies (Basel, Switzerland)

Lazova S, Velikova T, Priftis S, Petrova G.
PMID: 32640522
Antibodies (Basel). 2020 Jul 06;9(3). doi: 10.3390/antib9030031.

(1) Background: Asthma is a complex heterogeneous disease that likely comprises several distinct disease phenotypes, where the clustering approach has been used to classify the heterogeneous asthma population into distinct phenotypes; (2) Methods: For a period of 1 year,...

Biomarkers in Irritable Bowel Syndrome: Biological Rationale and Diagnostic Value.

Digestive diseases (Basel, Switzerland)

Nakov R, Snegarova V, Dimitrova-Yurukova D, Velikova T.
PMID: 33752201
Dig Dis. 2021 Mar 22; doi: 10.1159/000516027. Epub 2021 Mar 22.

BACKGROUND: Patients with irritable bowel syndrome (IBS) usually suffer from nonspecific and overlapping signs that hamper the diagnostic process. In line with this, biomarkers specific for IBS could be of great benefit for diagnosing and managing patients. In IBS,...

Challenges and updates in the management of eosinophilic esophagitis.

Przeglad gastroenterologiczny

Velikova T.
PMID: 32215124
Prz Gastroenterol. 2020;15(1):27-33. doi: 10.5114/pg.2019.84476. Epub 2019 Apr 12.

Eosinophilic esophagitis (EE) is a chronic T helper cell-2 mediated inflammatory condition and is considered as a primary cause of dysphagia and foregut symptoms. There are many challenges regarding the treatment options of EE. Different therapeutic approaches are best...

Association Between Preventive Behaviour and Anxiety at the Start of the COVID-19 Pandemic in Slovenia.

Zdravstveno varstvo

Velikonja NK, Erjavec K, Verdenik I, Hussein M, Velikonja VG.
PMID: 33488818
Zdr Varst. 2020 Dec 31;60(1):17-24. doi: 10.2478/sjph-2021-0004. eCollection 2020 Dec.

INTRODUCTION: The first large outbreak of SARS-CoV-2 in Europe occurred in Northern Italy in February 2020. The relatively fast spread of the infection to Slovenia was expected, and preventive measures for its suppression were widely discussed.METHODS: An online questionnaire...

Current concept for tertiary lymphoid structures in urothelial carcinoma of the bladder: a literature review and our experience.

American journal of clinical and experimental immunology

Gulinac M, Dikov D, Lichev S, Velikova T.
PMID: 33489474
Am J Clin Exp Immunol. 2020 Dec 15;9(5):64-72. eCollection 2020.

Bladder carcinoma (BC) is one of the most common malignancies of the urinary system in developed countries, with a high number of recurrences. The secondary lymphoid organs (SLO) are crucial for initiating the adaptive immune response. They are developed...

Biomarkers in Irritable Bowel Syndrome: biological rationale and diagnostic value.

Digestive diseases (Basel, Switzerland)

Nakov R, Snegarova V, Dimitrova-Yurukova D, Velikova T.
PMID: 33752201
Dig Dis. 2021 Mar 22; doi: 10.1159/000516027. Epub 2021 Mar 22.

Patients with irritable bowel syndrome (IBS) usually suffer from non-specific and overlapping signs that hamper the diagnostic process. In line with this, biomarkers specific for IBS could be of great benefit for diagnosing and managing patients. In IBS, the...

Cultured Cells Isolated from CNS Indolent B-Cell Lymphoma Have Characteristics of Mesenchymal Stem Cells: A Clinical Case and Scientific Research.

International journal of hematology-oncology and stem cell research

Tumagelova-Yuzeir K, Ivanova-Todorova E, Naydenov E, Velikova T, Krasimirova E, Belemezova K, Dikov T, Penkov M, Nachev S, Genova M, Kyurkchiev D.
PMID: 30595817
Int J Hematol Oncol Stem Cell Res. 2018 Jul 01;12(3):169-174.

The case report presented here describes the culturing and characterization of mesenchymal stem cells (MSCs) isolated from a primary indolent B-cell lymphoma, located in the CNS of an immunocompetent patient. The presence of such cells in the tumor mass...

The Role of Health Services in Encouraging Disclosure of Violence Against Women.

Zdravstveno varstvo

Leskošek V, Lučovnik M, Pavše L, Sršen TP, Krajnc M, Verdenik I, Velikonja VG.
PMID: 29062396
Zdr Varst. 2017 Oct 09;56(4):220-226. doi: 10.1515/sjph-2017-0030. eCollection 2017 Oct.

INTRODUCTION: The aim of the survey was to assess the differences in disclosure by the type of violence to better plan the role of health services in identifying and disclosing violence.METHODS: A validated, anonymous screening questionnaire (NorAQ) for the...

Factors affecting complications development and mortality after single lung transplant.

World journal of transplantation

Sekulovski M, Simonska B, Peruhova M, Krastev B, Peshevska-Sekulovska M, Spassov L, Velikova T.
PMID: 34447669
World J Transplant. 2021 Aug 18;11(8):320-334. doi: 10.5500/wjt.v11.i8.320.

Lung transplantation (LT) is a life-saving therapeutic procedure that prolongs survival in patients with end-stage lung disease. Furthermore, as a therapeutic option for high-risk candidates, single LT (SLT) can be feasible because the immediate morbidity and mortality after transplantation...

COVID-19 vaccination in autoimmune disease (COVAD) survey protocol.

Rheumatology international

Sen P, Gupta L, Lilleker JB, Aggarwal V, Kardes S, Milchert M, Gheita T, Salim B, Velikova T, Gracia-Ramos AE, Parodis I, O'Callaghan AS, Nikiphorou E, Tan AL, Cavagna L, Saavedra MA, Shinjo SK, Ziade N, Knitza J, Kuwana M, Cagnotto G, Nune A, Distler O, Chinoy H, Aggarwal V, Aggarwal R.
PMID: 34779868
Rheumatol Int. 2022 Jan;42(1):23-29. doi: 10.1007/s00296-021-05046-4. Epub 2021 Nov 15.

The coronavirus disease-2019 (COVID-19) pandemic continues to be a cause of unprecedented global morbidity and mortality. Whilst COVID-19 vaccination has emerged as the only tangible solution to reducing poor clinical outcomes, vaccine hesitancy continues to be an obstacle to...

Showing 1 to 12 of 31 entries