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Showing 1 to 12 of 49 entries
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Composition, antimicrobial, antioxidant, and antiproliferative activity of Origanum dictamnus (dittany) essential oil.

Microbial ecology in health and disease

Mitropoulou G, Fitsiou E, Stavropoulou E, Papavassilopoulou E, Vamvakias M, Pappa A, Oreopoulou A, Kourkoutas Y.
PMID: 25952773
Microb Ecol Health Dis. 2015 May 06;26:26543. doi: 10.3402/mehd.v26.26543. eCollection 2015.

BACKGROUND: Nowadays, there has been an increased interest in essential oils from various plant origins as potential antimicrobial, antioxidant, and antiproliferative agents. This trend can be mainly attributed to the rising number and severity of food poisoning outbreaks worldwide...

Pleiotropic effects of interleukin-6 in a "two-hit" murine model of acute respiratory distress syndrome.

Pulmonary circulation

Goldman JL, Sammani S, Kempf C, Saadat L, Letsiou E, Wang T, Moreno-Vinasco L, Rizzo AN, Fortman JD, Garcia JG.
PMID: 25006447
Pulm Circ. 2014 Jun;4(2):280-8. doi: 10.1086/675991.

Patients with acute respiratory distress syndrome (ARDS) exhibit elevated levels of interleukin-6 (IL-6), which correlate with increased morbidity and mortality. The exact role of IL-6 in ARDS has proven difficult to study because it exhibits either pro- or anti-inflammatory...

A new stem group echinoid from the Triassic of China leads to a revised macroevolutionary history of echinoids during the end-Permian mass extinction.

Royal Society open science

Thompson JR, Hu SX, Zhang QY, Petsios E, Cotton LJ, Huang JY, Zhou CY, Wen W, Bottjer DJ, Hallahan DP, Pullen PC.
PMID: 29410858
R Soc Open Sci. 2018 Jan 31;5(1):171548. doi: 10.1098/rsos.171548. eCollection 2018 Jan.

The Permian-Triassic bottleneck has long been thought to have drastically altered the course of echinoid evolution, with the extinction of the entire echinoid stem group having taken place during the end-Permian mass extinction. The Early Triassic fossil record of...

The ARP 2/3 complex mediates endothelial barrier function and recovery.

Pulmonary circulation

Belvitch P, Brown ME, Brinley BN, Letsiou E, Rizzo AN, Garcia JGN, Dudek SM.
PMID: 28680579
Pulm Circ. 2017 Feb 01;7(1):200-210. doi: 10.1086/690307. eCollection 2017 Mar.

Pulmonary endothelial cell (EC) barrier dysfunction and recovery is critical to the pathophysiology of acute respiratory distress syndrome. Cytoskeletal and subsequent cell membrane dynamics play a key mechanistic role in determination of EC barrier integrity. Here, we characterizAQe the...

On the Evaluation of a Novel Hypoxic 3D Pancreatic Cancer Model as a Tool for Radiotherapy Treatment Screening.

Cancers

Wishart G, Gupta P, Nisbet A, Schettino G, Velliou E.
PMID: 34885188
Cancers (Basel). 2021 Dec 02;13(23). doi: 10.3390/cancers13236080.

Tissue engineering is evolving to mimic intricate ecosystems of tumour microenvironments (TME) to more readily map realistic in vivo niches of cancerous tissues. Such advanced cancer tissue models enable more accurate preclinical assessment of treatment strategies. Pancreatic cancer is...

Deciphering the role of cartilage protein 1 in human dermal fibroblasts: a transcriptomic approach.

Functional & integrative genomics

Letsiou S, Manchado M, Zografaki M, Marka S, Anjos L, Skliros D, Martínez-Blanch JF, Flemetakis E, Power DM.
PMID: 34269961
Funct Integr Genomics. 2021 Jul;21(3):503-511. doi: 10.1007/s10142-021-00792-x. Epub 2021 Jul 16.

Cartilage acidic protein 1A (hCRTAC1-A) is an extracellular matrix protein (ECM) of human hard and soft tissue that is associated with matrix disorders. The central role of fibroblasts in tissue integrity and ECM health made primary human dermal fibroblasts...

Neutrophil-Derived Extracellular Vesicles Activate Platelets after Pneumolysin Exposure.

Cells

Letsiou E, Teixeira Alves LG, Felten M, Mitchell TJ, Müller-Redetzky HC, Dudek SM, Witzenrath M.
PMID: 34944089
Cells. 2021 Dec 18;10(12). doi: 10.3390/cells10123581.

Pneumolysin (PLY) is a pore-forming toxin of

Research Techniques Made Simple: Lipidomic Analysis in Skin Research.

The Journal of investigative dermatology

Sochorová M, Vávrová K, Fedorova M, Ni Z, Slenter D, Kutmon M, Willighagen EL, Letsiou S, Töröcsik D, Marchetti-Deschmann M, Zoratto S, Kremslehner C, Gruber F.
PMID: 34924150
J Invest Dermatol. 2022 Jan;142(1):4-11.e1. doi: 10.1016/j.jid.2021.09.017.

Although lipids are crucial molecules for cell structure, metabolism, and signaling in most organs, they have additional specific functions in the skin. Lipids are required for the maintenance and regulation of the epidermal barrier, physical properties of the skin,...

Neutrophil-Derived Extracellular Vesicles Activate Platelets after Pneumolysin Exposure.

Cells

Letsiou E, Teixeira Alves LG, Felten M, Mitchell TJ, Müller-Redetzky HC, Dudek SM, Witzenrath M.
PMID: 34944089
Cells. 2021 Dec 18;10(12). doi: 10.3390/cells10123581.

Pneumolysin (PLY) is a pore-forming toxin of

Secretory Phospholipase A.

Cell biochemistry and biophysics

Letsiou E, Htwe YM, Dudek SM.
PMID: 34105094
Cell Biochem Biophys. 2021 Sep;79(3):609-617. doi: 10.1007/s12013-021-01003-x. Epub 2021 Jun 08.

The secretory phospholipase A

The pleiotropic effects of Prunus avium L. extract against oxidative stress on human fibroblasts. An in vitro approach.

Molecular biology reports

Letsiou S, Karamaouna A, Ganopoulos I, Kapazoglou A, Xanthopoulou A, Sarrou E, Tanou G, Molassiotis A.
PMID: 34100152
Mol Biol Rep. 2021 May;48(5):4441-4448. doi: 10.1007/s11033-021-06464-0. Epub 2021 Jun 07.

There is a persistent interest in innovative and multifunctional ingredients in biology research. With regards to this, natural sources have an important role due to their multiple benefits. Thus, this study aims to present the pleiotropic activity of Prunus...

Automated microbeam observation environment for biological analysis-Custom portable environmental control applied to a vertical microbeam system.

Sensors and actuators. B, Chemical

England MJ, Bigelow AW, Merchant MJ, Velliou E, Welch D, Brenner DJ, Kirkby KJ.
PMID: 29515291
Sens Actuators B Chem. 2017 Feb;239:1134-1143. doi: 10.1016/j.snb.2016.08.076. Epub 2016 Aug 16.

Vertical Microbeams (VMB) are used to irradiate individual cells with low MeV energy ions. The irradiation of cells using VMBs requires cells to be removed from an incubator; this can cause physiological changes to cells because of the lower...

Showing 1 to 12 of 49 entries