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Assessing the effect of an evidence-based patient online educational tool for people with multiple sclerosis called UMIMS—understanding magnetic …

Educational trials

Vettorazzi E.
GSID: qNZ7kKKlm7AJ
I Schiffmann, M Freund, E Vettorazzi, JP Stellmann… - Trials, 2020 - Springer

… Because information sources about MRI in MS for pwMS are not available, we designed and evaluated an evidence-based online educational platform about MRI in MS called “Understanding MRI in MS” (UMIMS). Based on a pilot study in n=...

Calcium-to-creatinine ratio in pregnancy-induced hypertension.

Pregnancy hypertension

Gasnier R, Valério EG, Vettorazzi J, Martins-Costa SH, Barros EG, Ramos JG.
PMID: 26104992
Pregnancy Hypertens. 2012 Jan;2(1):59-64. doi: 10.1016/j.preghy.2011.10.003. Epub 2011 Nov 23.

OBJECTIVES: Hypocalciuria has been correlated with preeclampsia. This study compared the calcium-to-creatinine ratio among the groups, and the correlation with the 24-h measurement of this ratio and a diagnosis of preeclampsia.STUDY DESIGN: Case-control study including mild and severe preeclampsia,...

Augmented β-Cell Function and Mass in Glucocorticoid-Treated Rodents Are Associated with Increased Islet Ir-β /AKT/mTOR and Decreased AMPK/ACC and AS160 Signaling.

International journal of endocrinology

Protzek AO, Costa-Júnior JM, Rezende LF, Santos GJ, Araújo TG, Vettorazzi JF, Ortis F, Carneiro EM, Rafacho A, Boschero AC.
PMID: 25313308
Int J Endocrinol. 2014;2014:983453. doi: 10.1155/2014/983453. Epub 2014 Sep 17.

Glucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increased β-cell function is associated with increased insulin signaling that has the protein kinase B (AKT) substrate with 160...

Short-term interval aerobic exercise training does not improve memory functioning in relapsing-remitting multiple sclerosis-a randomized controlled trial.

PeerJ

Baquet L, Hasselmann H, Patra S, Stellmann JP, Vettorazzi E, Engel AK, Rosenkranz SC, Poettgen J, Gold SM, Schulz KH, Heesen C.
PMID: 30581662
PeerJ. 2018 Dec 12;6:e6037. doi: 10.7717/peerj.6037. eCollection 2018.

BACKGROUND: Only few aerobic exercise intervention trials specifically targeting cognitive functioning have been performed in multiple sclerosis.OBJECTIVE AND METHODS: This randomized controlled trial with 34 patients in the intervention group (IG) (mean: 38.2 years (±9.6)) and 34 patients in...

First Report of Phytophthora cambivora Causing Bleeding Cankers and Dieback on Beech (Fagus sylvatica) in Italy.

Plant disease

Belisario A, Maccaroni M, Vettorazzo M.
PMID: 30780960
Plant Dis. 2006 Oct;90(10):1362. doi: 10.1094/PD-90-1362C.

European beech (Fagus sylvatica) is an important forest tree species common in northern and central Europe. In Italy, this species is typical in mountain areas over 1,000 m above sea level. In the last decade, decline and death was...

Inhibition of sphingosine 1-phosphate protects mice against chondrocyte catabolism and osteoarthritis.

Osteoarthritis and cartilage

Cherifi C, Latourte A, Vettorazzi S, Tuckermann J, Provot S, Ea HK, Ledoux A, Casas J, Cuvillier O, Richette P, Ostertag A, Hay E, Cohen-Solal M.
PMID: 34144150
Osteoarthritis Cartilage. 2021 Sep;29(9):1335-1345. doi: 10.1016/j.joca.2021.06.001. Epub 2021 Jun 16.

OBJECTIVE: Cartilage loss observed in osteoarthritis (OA) is prevented when osteoclasts in the subchondral bone are inhibited in mice. Here, we investigated the role of the osteoclast secretome and of the lipid mediator sphingosine 1-phosphate (S1P) in chondrocyte metabolism...

Short Pulse and Conventional Deep Brain Stimulation Equally Improve the Parkinsonian Gait Disorder.

Journal of Parkinson's disease

Seger A, Gulberti A, Vettorazzi E, Braa H, Buhmann C, Gerloff C, Hamel W, Moll CKE, Pötter-Nerger M.
PMID: 34057096
J Parkinsons Dis. 2021;11(3):1455-1464. doi: 10.3233/JPD-202492.

BACKGROUND: Gait disturbances and balance remain challenging issues in Parkinsonian patients (PD) with deep brain stimulation (DBS). Short pulse deep brain stimulation (spDBS) increases the therapeutic window in PD patients, yet the effect on gait and postural symptoms remains...

A guide to changing paradigms of glucocorticoid receptor function-a model system for genome regulation and physiology.

The FEBS journal

Vettorazzi S, Nalbantoglu D, Gebhardt JCM, Tuckermann J.
PMID: 34213830
FEBS J. 2021 Jul 02; doi: 10.1111/febs.16100. Epub 2021 Jul 02.

The glucocorticoid receptor (GR) is a bona fide ligand-regulated transcription factor. Cloned in the 80s, the GR has become one of the best-studied and clinically most relevant members of the nuclear receptor superfamily. Cooperative activity of GR with other...

Long-term increase of insulin secretion in mice subjected to pregnancy and lactation.

Endocrine connections

Vicente JM, Santos-Silva JC, Teixeira CJ, de Souza DN, Vettorazzi JF, Furtuoso FS, Adabo IG, Sato FT, Vinolo MAR, Carneiro EM, Bordin S, Anhê GF.
PMID: 32182583
Endocr Connect. 2020 Apr;9(4):299-308. doi: 10.1530/EC-20-0020.

PURPOSE: Observational studies show that longer breastfeeding periods reduce maternal risk of type 2 diabetes mellitus. However, it is currently unknown if the long-term benefits of breastfeeding for maternal glucose homeostasis are linked to changes in the endocrine pancreas.METHODS:...

Corrigendum to "Novel approach for the detection of alkylated bases using the enzyme-modified comet assay" [Toxicol. Lett. 330 (2020) 108-117].

Toxicology letters

Muruzabal D, Sanz-Serrano J, Sauvaigo S, Gützkow KB, de Cerain AL, Vettorazzi A, Azqueta A.
PMID: 33172770
Toxicol Lett. 2020 Dec 15;335:98. doi: 10.1016/j.toxlet.2020.10.011. Epub 2020 Nov 07.

No abstract available.

Effect of nighttime light exposure on glucose metabolism in protein-restricted mice.

The Journal of endocrinology

Borck PC, Rickli S, Vettorazzi JF, Batista TM, Boschero AC, Vieira E, Carneiro EM.
PMID: 34647525
J Endocrinol. 2021 Oct 01; doi: 10.1530/JOE-21-0133. Epub 2021 Oct 01.

Disruption of biological rhythms due exposure to artificial light at night (ALAN) has been emerged as new risk factor for metabolic diseases. However, it remains largely unexplored the effects induced by exposure to ALAN on energy metabolism with concomitant...

TUDCA receptors and their role on pancreatic beta cells.

Progress in biophysics and molecular biology

Rosa LRO, Vettorazzi JF, Zangerolamo L, Carneiro EM, Barbosa HCL.
PMID: 34547326
Prog Biophys Mol Biol. 2021 Dec;167:26-31. doi: 10.1016/j.pbiomolbio.2021.09.003. Epub 2021 Sep 20.

Bile acids have received increasing attention over the past years as their multiple alternative roles became clearer. Tauroursodeoxycholic Acid (TUDCA) in specific has generated special interest due to its ability to promote pancreatic survival and function, as well as...

Showing 1 to 12 of 66 entries