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How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence.

Cancers

Forget P, Aguirre JA, Bencic I, Borgeat A, Cama A, Condron C, Eintrei C, Eroles P, Gupta A, Hales TG, Ionescu D, Johnson M, Kabata P, Kirac I, Ma D, Mokini Z, Guerrero Orriach JL, Retsky M, Sandrucci S, Siekmann W, Štefančić L, Votta-Vellis G, Connolly C, Buggy D.
PMID: 31035321
Cancers (Basel). 2019 Apr 28;11(5). doi: 10.3390/cancers11050592.

The question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. A wealth of experimental and observational clinical data have been published,...

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Forget P, Aguirre JA, Bencic I, et al. How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence. Cancers (Basel). 2019;11(5)doi: 10.3390/cancers11050592.
Forget, P., Aguirre, J. A., Bencic, I., Borgeat, A., Cama, A., Condron, C., Eintrei, C., Eroles, P., Gupta, A., Hales, T. G., Ionescu, D., Johnson, M., Kabata, P., Kirac, I., Ma, D., Mokini, Z., Guerrero Orriach, J. L., Retsky, M., Sandrucci, S., Siekmann, W., Štefančić, L., Votta-Vellis, G., Connolly, C., & Buggy, D. (2019). How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence. Cancers, 11(5), . https://doi.org/10.3390/cancers11050592
Forget, Patrice, et al. "How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence." Cancers vol. 11,5 (2019). doi: https://doi.org/10.3390/cancers11050592
Forget P, Aguirre JA, Bencic I, Borgeat A, Cama A, Condron C, Eintrei C, Eroles P, Gupta A, Hales TG, Ionescu D, Johnson M, Kabata P, Kirac I, Ma D, Mokini Z, Guerrero Orriach JL, Retsky M, Sandrucci S, Siekmann W, Štefančić L, Votta-Vellis G, Connolly C, Buggy D. How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence. Cancers (Basel). 2019 Apr 28;11(5). doi: 10.3390/cancers11050592. PMID: 31035321; PMCID: PMC6563034.
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Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain.

Gene reports

Das V, Kc R, Li X, O-Sullivan I, van Wijnen AJ, Kroin JS, Pytowski B, Applegate DT, Votta-Velis G, Ripper RL, Park TJ, Im HJ.
PMID: 30873504
Gene Rep. 2018 Jun;11:94-100. doi: 10.1016/j.genrep.2018.03.008. Epub 2018 Mar 08.

Osteoarthritis (OA) is a painful and debilitating disease. A striking feature of OA is the dramatic increase in vascular endothelial growth factor (VEGF) levels and in new blood vessel formation in the joints, both of which correlate with the...

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Das V, Kc R, Li X, et al. Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain. Gene Rep. 2018;11:94-100doi: 10.1016/j.genrep.2018.03.008.
Das, V., Kc, R., Li, X., O-Sullivan, I., van Wijnen, A. J., Kroin, J. S., Pytowski, B., Applegate, D. T., Votta-Velis, G., Ripper, R. L., Park, T. J., & Im, H. J. (2018). Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain. Gene reports, 1194-100. https://doi.org/10.1016/j.genrep.2018.03.008
Das, Vaskar, et al. "Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain." Gene reports vol. 11 (2018): 94-100. doi: https://doi.org/10.1016/j.genrep.2018.03.008
Das V, Kc R, Li X, O-Sullivan I, van Wijnen AJ, Kroin JS, Pytowski B, Applegate DT, Votta-Velis G, Ripper RL, Park TJ, Im HJ. Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain. Gene Rep. 2018 Jun;11:94-100. doi: 10.1016/j.genrep.2018.03.008. Epub 2018 Mar 08. PMID: 30873504; PMCID: PMC6411090.
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Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury.

Pulmonary circulation

Maniatis NA, Kardara M, Hecimovich D, Letsiou E, Castellon M, Roussos C, Shinin V, Votta-Vellis EG, Schwartz DE, Minshall RD.
PMID: 23372929
Pulm Circ. 2012 Oct;2(4):452-60. doi: 10.4103/2045-8932.105033.

Caveolin-1 is a key regulator of pulmonary endothelial barrier function. Here, we tested the hypothesis that caveolin-1 expression is required for ventilator-induced lung injury (VILI). Caveolin-1 gene-disrupted (Cav-1(-/-)) and age-, sex-, and strain-matched wild-type (WT) control mice were ventilated...

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Maniatis NA, Kardara M, Hecimovich D, et al. Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury. Pulm Circ. 2012;2(4):452-60doi: 10.4103/2045-8932.105033.
Maniatis, N. A., Kardara, M., Hecimovich, D., Letsiou, E., Castellon, M., Roussos, C., Shinin, V., Votta-Vellis, E. G., Schwartz, D. E., & Minshall, R. D. (2012). Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury. Pulmonary circulation, 2(4), 452-60. https://doi.org/10.4103/2045-8932.105033
Maniatis, Nikolaos A, et al. "Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury." Pulmonary circulation vol. 2,4 (2012): 452-60. doi: https://doi.org/10.4103/2045-8932.105033
Maniatis NA, Kardara M, Hecimovich D, Letsiou E, Castellon M, Roussos C, Shinin V, Votta-Vellis EG, Schwartz DE, Minshall RD. Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury. Pulm Circ. 2012 Oct;2(4):452-60. doi: 10.4103/2045-8932.105033. PMID: 23372929; PMCID: PMC3555415.
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