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Showing 1 to 12 of 49 entries
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Development and preliminary evaluation of the validity and reliability of a revised illness perception questionnaire for healthcare professionals.

BMC nursing

Arat S, Van den Zegel A, Van Rillaer M, Moons P, Vandenberghe J, De Langhe E, Westhovens R.
PMID: 27252595
BMC Nurs. 2016 Jun 01;15:34. doi: 10.1186/s12912-016-0156-4. eCollection 2016.

BACKGROUND: Diverging perceptions between individual patients with somatic diseases and their healthcare professionals might cause problems in communication and decision-making. To date, no measurement tool is available to compare the illness perceptions between these two groups. The Revised Illness...

Illness representations of systemic lupus erythematosus and systemic sclerosis: a comparison of patients, their rheumatologists and their general practitioners.

Lupus science & medicine

Arat S, Lenaerts JL, De Langhe E, Verschueren P, Moons P, Vandenberghe J, Taelman V, Westhovens R.
PMID: 29177061
Lupus Sci Med. 2017 Nov 14;4(1):e000232. doi: 10.1136/lupus-2017-000232. eCollection 2017.

OBJECTIVE: Discrepancies in illness representations between patients and physicians result in treatment difficulties, decreased well-being of patients and misunderstandings and disrupted communication. Hence, the objective of this study was to compare illness perceptions of individual patients with systemic lupus...

Identification of biomarkers of response to abatacept in patients with SLE using deconvolution of whole blood transcriptomic data from a phase IIb clinical trial.

Lupus science & medicine

Bandyopadhyay S, Connolly SE, Jabado O, Ye J, Kelly S, Maldonado MA, Westhovens R, Nash P, Merrill JT, Townsend RM.
PMID: 29214034
Lupus Sci Med. 2017 Jul 28;4(1):e000206. doi: 10.1136/lupus-2017-000206. eCollection 2017.

OBJECTIVE: To characterise patients with active SLE based on pretreatment gene expression-defined peripheral immune cell patterns and identify clusters enriched for potential responders to abatacept treatment.METHODS: This post hoc analysis used baseline peripheral whole blood transcriptomic data from patients...

The perspective of patients with early rheumatoid arthritis on the journey from symptom onset until referral to a rheumatologist.

Rheumatology advances in practice

De Cock D, Van der Elst K, Stouten V, Peerboom D, Joly J, Westhovens R, Verschueren P.
PMID: 32083241
Rheumatol Adv Pract. 2019 Aug 30;3(2):rkz035. doi: 10.1093/rap/rkz035. eCollection 2019.

OBJECTIVE: Timely treatment of patients with early RA (ERA) favours a beneficial disease outcome. However, individuals often delay their contact with a health-care professional (HCP) after ERA-related symptom onset. The aim of this study was to investigate the perspective...

Foreword from the judges.

Rheumatology advances in practice

Tan AL, Westhovens R, Ndosi M.
PMID: 34755029
Rheumatol Adv Pract. 2021 Nov 05;5:iia. doi: 10.1093/rap/rkab080. eCollection 2021 Nov.

No abstract available.

Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial.

Annals of the rheumatic diseases

Westhovens R, Rigby WFC, van der Heijde D, Ching DWT, Stohl W, Kay J, Chopra A, Bartok B, Matzkies F, Yin Z, Guo Y, Tasset C, Sundy JS, Jahreis A, Mozaffarian N, Messina OD, Landewé RB, Atsumi T, Burmester GR.
PMID: 33452004
Ann Rheum Dis. 2021 Jan 15; doi: 10.1136/annrheumdis-2020-219213. Epub 2021 Jan 15.

OBJECTIVES: To investigate efficacy and safety of the Janus kinase-1 inhibitor filgotinib in patients with active rheumatoid arthritis (RA) with limited or no prior methotrexate (MTX) exposure.METHODS: This 52-week, phase 3, multicentre, double-blind clinical trial (NCT02886728) evaluated once-daily oral...

Intravenous pegylated liposomal prednisolone outperforms intramuscular methylprednisolone in treating rheumatoid arthritis flares: A randomized controlled clinical trial.

Journal of controlled release : official journal of the Controlled Release Society

Metselaar JM, Middelink LM, Wortel CH, Bos R, van Laar JM, Vonkeman HE, Westhovens R, Lammers T, Yao SL, Kothekar M, Raut A, Bijlsma JWJ.
PMID: 34896445
J Control Release. 2021 Dec 10;341:548-554. doi: 10.1016/j.jconrel.2021.12.007. Epub 2021 Dec 10.

Glucocorticoids (GCs) are potent anti-inflammatory drugs but their use is limited by systemic exposure leading to toxicity. Targeted GC delivery to sites of inflammation via encapsulation in long-circulating liposomes may improve the therapeutic index. We performed a randomized, double-blind,...

Five-year treat-to-target outcomes after methotrexate induction therapy with or without other csDMARDs and temporary glucocorticoids for rheumatoid arthritis in the CareRA trial.

Annals of the rheumatic diseases

Stouten V, Westhovens R, Pazmino S, De Cock D, Van der Elst K, Joly J, Bertrand D, Verschueren P.
PMID: 33811036
Ann Rheum Dis. 2021 Apr 02; doi: 10.1136/annrheumdis-2020-219825. Epub 2021 Apr 02.

OBJECTIVES: To compare outcomes of different treatment schedules from the care in early rheumatoid arthritis (CareRA) trial over 5 years.METHODS: Patients with RA completing the 2-year CareRA randomised controlled trial were eligible for the 3-year observational CareRA-plus study. 5-year...

Efficacy and safety of filgotinib alone and in combination with methotrexate in Japanese patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: Subpopulation analyses of 24-week data of a global phase 3 study (FINCH 3).

Modern rheumatology

Atsumi T, Tanaka Y, Matsubara T, Amano K, Ishiguro N, Sugiyama E, Yamaoka K, Westhovens R, Ching DWT, Messina OD, Burmester GR, Bartok B, Pechonkina A, Kondo A, Yin Z, Guo Y, Tasset C, Sundy JS, Takeuchi T.
PMID: 34910203
Mod Rheumatol. 2021 Oct 07; doi: 10.1093/mr/roab021. Epub 2021 Oct 07.

OBJECTIVES: To evaluate the efficacy and safety of filgotinib for Japanese patients with rheumatoid arthritis (RA) and limited or no prior methotrexate (MTX) exposure.METHODS: Data up to 24 weeks were analysed for 71 Japanese patients from a 52-week global...

A Review of Persuasive Principles in Mobile Apps for Chronic Arthritis Patients: Opportunities for Improvement.

JMIR mHealth and uHealth

Geuens J, Swinnen TW, Westhovens R, de Vlam K, Geurts L, Vanden Abeele V.
PMID: 27742604
JMIR Mhealth Uhealth. 2016 Oct 13;4(4):e118. doi: 10.2196/mhealth.6286.

BACKGROUND: Chronic arthritis (CA), an umbrella term for inflammatory rheumatic and other musculoskeletal diseases, is highly prevalent. Effective disease-modifying antirheumatic drugs for CA are available, with the exception of osteoarthritis, but require a long-term commitment of patients to comply...

Perspectives on Subcutaneous Infliximab for Rheumatic Diseases and Inflammatory Bowel Disease: Before, During, and After the COVID-19 Era.

Advances in therapy

Schreiber S, Ben-Horin S, Alten R, Westhovens R, Peyrin-Biroulet L, Danese S, Hibi T, Takeuchi K, Magro F, An Y, Kim DH, Yoon S, Reinisch W.
PMID: 34988877
Adv Ther. 2022 Jan 06; doi: 10.1007/s12325-021-01990-6. Epub 2022 Jan 06.

The coronavirus disease 2019 (COVID-19) pandemic has prompted significant changes in patient care in rheumatology and gastroenterology, with clinical guidance issued to manage ongoing therapy while minimising the risk of nosocomial infection for patients and healthcare professionals (HCPs). Subcutaneous...

Titre-specific positive predictive value of antinuclear antibody patterns.

Annals of the rheumatic diseases

Vulsteke JB, Van Hoovels L, Willems P, Vander Cruyssen B, Vanderschueren S, Westhovens R, Blockmans D, De Langhe E, Bossuyt X.
PMID: 31601627
Ann Rheum Dis. 2019 Oct 10; doi: 10.1136/annrheumdis-2019-216245. Epub 2019 Oct 10.

No abstract available.

Showing 1 to 12 of 49 entries