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Showing 1 to 12 of 334 entries
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Peptide array functionalization via the Ugi four-component reaction.

Chemical communications (Cambridge, England)

Ridder B, Mattes DS, Nesterov-Mueller A, Breitling F, Meier MAR.
PMID: 28474022
Chem Commun (Camb). 2017 May 17;53(40):5553-5556. doi: 10.1039/c7cc01945a.

The Ugi four-component reaction was investigated as a tool for the functionalization of peptide arrays via post-synthetic side-chain modification, mimicking post-translational processes. Additionally, as a proof of concept for the synthesis of peptidomimetics on arrays, the integration of an...

Patient engagement with surgical site infection prevention: an expert panel perspective.

Antimicrobial resistance and infection control

Tartari E, Weterings V, Gastmeier P, Rodríguez Baño J, Widmer A, Kluytmans J, Voss A.
PMID: 28507731
Antimicrob Resist Infect Control. 2017 May 12;6:45. doi: 10.1186/s13756-017-0202-3. eCollection 2017.

Despite remarkable developments in the use of surgical techniques, ergonomic advancements in the operating room, and implementation of bundles, surgical site infections (SSIs) remain a substantial burden, associated with increased morbidity, mortality and healthcare costs. National and international recommendations...

Of means and ends: The financialization and regulation of health care.

The Linacre quarterly

Widmer A.
PMID: 28392588
Linacre Q. 2016 Nov;83(4):382-386. doi: 10.1080/00243639.2016.1248168.

Health care is at a critical stage: doctors and patients, the central protagonists in this field, are less and less satisfied with the outcomes. Much of the debate about health care has focused on the choice between large public...

Bottom-Up Synthesis of Metalated Carbyne.

Journal of the American Chemical Society

Sun Q, Cai L, Wang S, Widmer R, Ju H, Zhu J, Li L, He Y, Ruffieux P, Fasel R, Xu W.
PMID: 26780188
J Am Chem Soc. 2016 Feb 03;138(4):1106-9. doi: 10.1021/jacs.5b10725. Epub 2016 Jan 20.

Because of stability issues, carbyne, a one-dimensional chain of carbon atoms, has been much less investigated than other recent carbon allotropes such as graphene. Beyond that, metalation of such a linear carbon nanostructure with regularly distributed metal atoms is...

Reply to Werth et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Berbari EF, Kanj SS, Kowalski TJ, Darouiche RO, Widmer A, Schmitt SK, Hendershot E, Holtom P, Huddleston P, Petermann G, Osmon D.
PMID: 27161779
Clin Infect Dis. 2016 Jul 15;63(2):282. doi: 10.1093/cid/ciw287. Epub 2016 May 08.

No abstract available.

Exciton Diffusion Length and Charge Extraction Yield in Organic Bilayer Solar Cells.

Advanced materials (Deerfield Beach, Fla.)

Siegmund B, Sajjad MT, Widmer J, Ray D, Koerner C, Riede M, Leo K, Samuel ID, Vandewal K.
PMID: 28145601
Adv Mater. 2017 Mar;29(12). doi: 10.1002/adma.201604424. Epub 2017 Feb 01.

A method for resolving the diffusion length of excitons and the extraction yield of charge carriers is presented based on the performance of organic bilayer solar cells and careful modeling. The technique uses a simultaneous variation of the absorber...

The U.S. Drug Policy Landscape: Insights and Opportunities for Improving the View.

Rand health quarterly

Kilmer B, Caulkins JP, Pacula RL, Reuter PH.
PMID: 28083261
Rand Health Q. 2012 Sep 01;2(3):2. eCollection 2012.

Discussions about reducing the harms associated with drug use and antidrug policies are often politicized, infused with questionable data, and unproductive. This article provides an overview of a nonpartisan primer that should be of interest to those who are...

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases.

EMBO molecular medicine

Regula JT, Lundh von Leithner P, Foxton R, Barathi VA, Gemmy Cheung CM, Bo Tun SB, Wey YS, Iwata D, Dostalek M, Moelleken J, Stubenrauch KG, Nogoceke E, Widmer G, Strassburger P, Koss MJ, Klein C, Shima DT, Hartmann G.
PMID: 28533211
EMBO Mol Med. 2017 Jul;9(7):985. doi: 10.15252/emmm.201707895.

No abstract available.

Use of enzymes in peptide synthesis.

Applied biochemistry and biotechnology

Chaiken IM, Komoriya A, Ohno M, Widmer F.
PMID: 24234364
Appl Biochem Biotechnol. 1982 Sep;7(5):385-99. doi: 10.1007/BF02798320.

Recent experiments in several laboratories have emphasized the benefits of proteolytic enzymes as effective catalysts for the formation of peptide bonds for synthesis and semisynthesis. This review summarizes successful applications in both stepwise synthesis for small peptides and fragment...

[Less is more--less is nothing].

Revue medicale suisse

Widmer D.
PMID: 26672185
Rev Med Suisse. 2015 Oct 28;11(492):2038-9.

No abstract available.

Toward an Ecologically Optimized N:P Recovery from Wastewater by Microalgae.

Frontiers in microbiology

Fernandes TV, Suárez-Muñoz M, Trebuch LM, Verbraak PJ, Van de Waal DB.
PMID: 28955317
Front Microbiol. 2017 Sep 11;8:1742. doi: 10.3389/fmicb.2017.01742. eCollection 2017.

Global stores of important resources such as phosphorus (P) are being rapidly depleted, while the excessive use of nutrients has led to the enrichment of surface waters worldwide. Ideally, nutrients would be recovered from wastewater, which will not only...

Back to the Future of Soil Metagenomics.

Frontiers in microbiology

Nesme J, Achouak W, Agathos SN, Bailey M, Baldrian P, Brunel D, Frostegård Å, Heulin T, Jansson JK, Jurkevitch E, Kruus KL, Kowalchuk GA, Lagares A, Lappin-Scott HM, Lemanceau P, Le Paslier D, Mandic-Mulec I, Murrell JC, Myrold DD, Nalin R, Nannipieri P, Neufeld JD, O'Gara F, Parnell JJ, Pühler A, Pylro V, Ramos JL, Roesch LF, Schloter M, Schleper C, Sczyrba A, Sessitsch A, Sjöling S, Sørensen J, Sørensen SJ, Tebbe CC, Topp E, Tsiamis G, van Elsas JD, van Keulen G, Widmer F, Wagner M, Zhang T, Zhang X, Zhao L, Zhu YG, Vogel TM, Simonet P.
PMID: 26903960
Front Microbiol. 2016 Feb 10;7:73. doi: 10.3389/fmicb.2016.00073. eCollection 2016.

No abstract available.

Showing 1 to 12 of 334 entries