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Showing 1 to 12 of 78 entries
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The Rijksuniversiteit Limburg, Maastricht, Netherlands: development of medical education.

Public health papers

Bouhuijs PA, Schmidt HG, Snow RE, Wijnen WH.
PMID: 695670
Public Health Pap. 1978;70:133-51.

No abstract available.

DISCRETE-CHOICE EXPERIMENT VERSE RATING SCALE EXERCISE TO EVALUATE THE RELATIVE IMPORTANCE OF ATTRIBUTES: A STUDY OF THE MAASTRICHT ISPOR STUDENT CHAPTER.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Wijnen BF, van der Putten IM, Groothuis S, de Kinderen RJ, Noben CY, Paulus AT, Ramaekers BL, Vogel GC, Hiligsmann M.
PMID: 27201891
Value Health. 2014 Nov;17(7):A568. doi: 10.1016/j.jval.2014.08.1893. Epub 2014 Oct 26.

No abstract available.

Splicing analysis for exonic and intronic mismatch repair gene variants associated with Lynch syndrome confirms high concordance between minigene assays and patient RNA analyses.

Molecular genetics & genomic medicine

van der Klift HM, Jansen AM, van der Steenstraten N, Bik EC, Tops CM, Devilee P, Wijnen JT.
PMID: 26247049
Mol Genet Genomic Med. 2015 Jul;3(4):327-45. doi: 10.1002/mgg3.145. Epub 2015 Apr 23.

A subset of DNA variants causes genetic disease through aberrant splicing. Experimental splicing assays, either RT-PCR analyses of patient RNA or functional splicing reporter minigene assays, are required to evaluate the molecular nature of the splice defect. Here, we...

Your conflict matters to me! Behavioral and neural manifestations of control adjustment after self-experienced and observed decision-conflict.

Frontiers in human neuroscience

Winkel J, Wijnen JG, Ridderinkhof KR, Groen II, Derrfuss J, Danielmeier C, Forstmann BU.
PMID: 20198103
Front Hum Neurosci. 2009 Dec 04;3:57. doi: 10.3389/neuro.09.057.2009. eCollection 2009.

In everyday life we tune our behavior to a rapidly changing environment as well as to the behavior of others. The behavioral and neural underpinnings of such adaptive mechanisms are the focus of the present study. In a social...

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia.

British journal of cancer

Schubert SA, Ruano D, Elsayed FA, Boot A, Crobach S, Sarasqueta AF, Wolffenbuttel B, van der Klauw MM, Oosting J, Tops CM, van Eijk R, Vasen HF, Vossen RH, Nielsen M, Castellví-Bel S, Ruiz-Ponte C, Tomlinson I, Dunlop MG, Vodicka P, Wijnen JT, Hes FJ, Morreau H, de Miranda NF, Sijmons RH, van Wezel T.
PMID: 29361631
Br J Cancer. 2018 Jan;118(2):e4. doi: 10.1038/bjc.2017.380. Epub 2017 Oct 12.

No abstract available.

Effects of maternal dietary nitrate supplementation during the perinatal period on piglet survival, body weight, and litter uniformity.

Translational animal science

van den Bosch M, Wijnen J, van de Linde IB, van Wesel AAM, Melchior D, Kemp B, Clouard C, van den Brand H.
PMID: 32704817
Transl Anim Sci. 2019 Feb 07;3(1):464-472. doi: 10.1093/tas/txy137. eCollection 2019 Jan.

The objective of this study was to evaluate effects of different dosages of dietary nitrate supplementation to sows from d 108 of gestation until d 5 of lactation on reproductive performance of sows and piglet performance from birth until...

Neurocardiovascular coupling in congenital diaphragmatic hernia patients undergoing different types of surgical treatment.

European journal of anaesthesiology

Hendrikx D, Costerus SA, Zahn K, Perez-Ortiz A, Caicedo Dorado A, Van Huffel S, de Graaff J, Wijnen R, Wessel L, Tibboel D, Naulaers G.
PMID: 34860716
Eur J Anaesthesiol. 2021 Dec 01; doi: 10.1097/EJA.0000000000001642. Epub 2021 Dec 01.

BACKGROUND: The effect of peri-operative management on the neonatal brain is largely unknown. Triggers for peri-operative brain injury might be revealed by studying changes in neonatal physiology peri-operatively.OBJECTIVE: To study neonatal pathophysiology and cerebral blood flow regulation peri-operatively using...

Correction to: Building a trusted framework for uncertainty assessment in rare diseases: suggestions for improvement (Response to "TRUST4RD: tool for reducing uncertainties in the evidence generation for specialised treatments for rare diseases").

Orphanet journal of rare diseases

Grimm SE, Pouwels X, Ramaekers BLT, Wijnen B, Knies S, Grutters J, Joore MA.
PMID: 34281581
Orphanet J Rare Dis. 2021 Jul 19;16(1):320. doi: 10.1186/s13023-021-01938-7.

No abstract available.

Nonoperative management of hip fractures in very frail elderly patients may lead to a predictable short survival as part of advance care planning.

Acta orthopaedica

Wijnen HH, Schmitz PP, Es-Safraouy H, Roovers LA, Taekema DG, Van Susante JLC.
PMID: 34319206
Acta Orthop. 2021 Dec;92(6):728-732. doi: 10.1080/17453674.2021.1959155. Epub 2021 Jul 28.

Background and purpose - Surgical treatment is still the mainstay of care even in very frail elderly hip fracture patients. However, one may argue whether surgery is in the best interest of all patients. We elucidated mortality rates of...

Mogamulizumab for Previously Treated Mycosis Fungoides and Sézary Syndrome: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

PharmacoEconomics

Grimm SE, Witlox W, Wolff R, Chalker A, Hiligsmann M, Wijnen B, Ahmadu C, Ryder S, Armstrong N, Duffy S, Syndikus I, Kleijnen J, Joore MA.
PMID: 34664200
Pharmacoeconomics. 2021 Oct 19; doi: 10.1007/s40273-021-01098-3. Epub 2021 Oct 19.

The National Institute for Health and Care Excellence (NICE) invited the manufacturer (Kyowa Kirin) of mogamulizumab (Poteligeo

Centralization of pediatric surgical care in the Netherlands: Lessons learned.

Journal of pediatric surgery

Wijnen MH, Hulscher JB.
PMID: 34836641
J Pediatr Surg. 2021 Oct 29; doi: 10.1016/j.jpedsurg.2021.10.023. Epub 2021 Oct 29.

Centralization of care is a difficult process, as there are several stakeholders that are involved and should be heard. What can be the best option for a small group of patients may be detrimental to a larger group of...

The effects of antidiabetic agents on heart failure.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Wijnen M, Duschek EJJ, Boom H, van Vliet M.
PMID: 34097240
Neth Heart J. 2021 Jun 07; doi: 10.1007/s12471-021-01579-2. Epub 2021 Jun 07.

In the Netherlands, approximately 250,000 people are living with heart failure. About one-third of them have comorbid diabetes mellitus type 2. Until recently, the effects of antidiabetic agents on heart failure were largely unknown. This changed after an observed...

Showing 1 to 12 of 78 entries