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Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties.

Journal of lipids

Schweikert EM, Amort J, Wilgenbus P, Förstermann U, Teiber JF, Horke S.
PMID: 22570791
J Lipids. 2012;2012:352857. doi: 10.1155/2012/352857. Epub 2012 Apr 12.

The pathogen Pseudomonas aeruginosa causes serious damage in immunocompromised patients by secretion of various virulence factors, among them the quorum sensing N-(3-oxododecanoyl)-L-homoserine lactone (3OC12) and the redox-active pyocyanin (PCN). Paraoxonase-2 (PON2) may protect against P. aeruginosa infections, as it...

Showing 1 to 1 of 1 entries