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Showing 1 to 12 of 76 entries
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Hydroalumination of Ketenimines and Subsequent Reactions with Heterocumulenes: Synthesis of Unsaturated Amide Derivatives and 1,3-Diimines.

The Journal of organic chemistry

Jin X, Willeke M, Lucchesi R, Daniliuc CG, Fröhlich R, Wibbeling B, Uhl W, Würthwein EU.
PMID: 26031425
J Org Chem. 2015 Jun 19;80(12):6062-75. doi: 10.1021/acs.joc.5b00466. Epub 2015 Jun 02.

The series of differently substituted ketenimines 1 was hydroluminated using di-iso-butyl aluminum hydride. For the sterically congested ketenimine 1a, preferred hydroalumination of the C═N-bond was proven by X-ray crystallography (compound 5a). In situ treatment of the hydroaluminated ketenimines 5...

Organelles involved in the synthesis and transport of hydroxyproline-containing glycoproteins in carrot root discs.

Planta

Wienecke K, Glas R, Robinson DG.
PMID: 24271627
Planta. 1982 Jun;155(1):58-63. doi: 10.1007/BF00402932.

Isopycnic sucrose density gradients of homogenates from carrot root tissue were analyzed radiochromatographically, radiochemically, and photometrically for the presence of hydroxyproline residues. Significant amounts were found in endoplasmic reticulum (ER), Golgi apparatus (GA) and plasma membrane (PM) fractions as...

High-resolution spectroscopic studies and theory of parity violation in chiral molecules.

Annual review of physical chemistry

Quack M, Stohner J, Willeke M.
PMID: 18173376
Annu Rev Phys Chem. 2008;59:741-69. doi: 10.1146/annurev.physchem.58.032806.104511.

We review the high-resolution spectroscopic approach toward the study of intramolecular dynamics, emphasizing molecular parity violation. Theoretical work in the past decade has shown that parity-violating potentials in chiral molecules are much larger (typically one to two orders of...

Isotopic chirality and molecular parity violation.

Angewandte Chemie (International ed. in English)

Berger R, Laubender G, Quack M, Sieben A, Stohner J, Willeke M.
PMID: 15880539
Angew Chem Int Ed Engl. 2005 Jun 06;44(23):3623-6. doi: 10.1002/anie.200462088.

No abstract available.

Spectroscopic properties of trichlorofluoromethane CCl(3)F calculated by density functional theory.

Physical chemistry chemical physics : PCCP

von Lilienfeld O, Léonard C, Handy NC, Carter S, Willeke M, Quack M.
PMID: 17851599
Phys Chem Chem Phys. 2007 Sep 28;9(36):5027-35. doi: 10.1039/b704995a. Epub 2007 Jul 23.

Density functional theory is used to generate local potential energy surfaces in normal coordinates for several chlorine isotopomers of trichlorofluoromethane (CCl(3)F, CFC11). An examination of predicted structures suggested that the PBE0 functional would be suitable. Anharmonic surfaces around the...

First Experiences with the New Senhance® Telerobotic System in Visceral Surgery.

Visceral medicine

Stephan D, Sälzer H, Willeke F.
PMID: 29594167
Visc Med. 2018 Feb;34(1):31-36. doi: 10.1159/000486111. Epub 2018 Feb 16.

Until recently, robotic-assisted surgery has exclusively been connected to the name DaVinci®. In 2016, a second robotic system, the Senhance®, became available. To introduce the new robotic system into clinical routine, detailed team training and an integration program were...

Piloting CanCope: An internet-delivered transdiagnostic intervention to improve mental health in cancer survivors.

Psycho-oncology

Smith IS, Wellecke C, Weihs KL, Bei B, Wiley JF.
PMID: 34425036
Psychooncology. 2022 Jan;31(1):107-115. doi: 10.1002/pon.5787. Epub 2021 Aug 23.

OBJECTIVE: CanCope is an internet-delivered, cognitive-behavioural intervention adapted from the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders to improve emotion regulation and support the mental health of cancer survivors. Four separate pilot studies evaluated each of CanCope's modules...

Pneumoretroperitoneum after a STARR Procedure Performed One Year after a Posterior Colporrhaphy: A Case Report and Review of the Literature.

Visceral medicine

Darwich I, Melekian B, Demirel-Darwich S, Willeke F.
PMID: 34722728
Visc Med. 2021 Oct;37(5):443-446. doi: 10.1159/000511933. Epub 2020 Nov 19.

Transanal rectal resection with a stapling instrument (STARR) has been shown to be effective and safe for the treatment of obstructed defecation syndrome (ODS). Nevertheless, the wide range of complications described in the literature necessitates a rigorous patient selection...

Evaluation and Refinement of Sample Preparation Methods for Extracellular Matrix Proteome Coverage.

Molecular & cellular proteomics : MCP

McCabe MC, Schmitt LR, Hill RC, Dzieciatkowska M, Maslanka M, Daamen WF, van Kuppevelt TH, Hof DJ, Hansen KC.
PMID: 33845168
Mol Cell Proteomics. 2021;20:100079. doi: 10.1016/j.mcpro.2021.100079. Epub 2021 Jun 03.

The extracellular matrix is a key component of tissues, yet it is underrepresented in proteomic datasets. Identification and evaluation of proteins in the extracellular matrix (ECM) has proved challenging due to the insolubility of many ECM proteins in traditional...

Graphene nanogaps for the directed assembly of single-nanoparticle devices.

Nanoscale

Cully JJ, Swett JL, Willick K, Baugh J, Mol JA.
PMID: 33885530
Nanoscale. 2021 Apr 07;13(13):6513-6520. doi: 10.1039/d1nr01450a. Epub 2021 Mar 24.

Significant advances in the synthesis of low-dimensional materials with unique and tuneable electrical, optical and magnetic properties has led to an explosion of possibilities for realising hybrid nanomaterial devices with unconventional and desirable characteristics. However, the lack of ability...

Polarized Secretion of APRIL by the Tonsil Epithelium Upon Toll-Like Receptor Stimulation.

Frontiers in immunology

Sturm N, Quinterot M, Guyot JP, Righini C, Daamen WF, van Kuppevelt TH, Huard B.
PMID: 34484218
Front Immunol. 2021 Aug 18;12:715724. doi: 10.3389/fimmu.2021.715724. eCollection 2021.

In mucosa such as tonsil, antibody-producing plasmocytes (PCs) lie in sub-epithelium space, which is thought to provide a suitable environment for their survival. A proliferation inducing ligand (APRIL) is one key survival factor for PCs present in this area....

Discussing Personalized Prognosis Empowers Patients with Amyotrophic Lateral Sclerosis to Regain Control over Their Future: A Qualitative Study.

Brain sciences

van Eenennaam RM, Koppenol LS, Kruithof WJ, Kruitwagen-van Reenen ET, Pieters S, van Es MA, van den Berg LH, Visser-Meily JMA, Beelen A.
PMID: 34942899
Brain Sci. 2021 Nov 30;11(12). doi: 10.3390/brainsci11121597.

The ENCALS survival prediction model offers patients with amyotrophic lateral sclerosis (ALS) the opportunity to receive a personalized prognosis of survival at the time of diagnosis. We explored experiences of patients with ALS, caregivers, and physicians with discussing personalized...

Showing 1 to 12 of 76 entries