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Showing 1 to 12 of 19 entries
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Environmentally induced, occupational diseases with emphasis on chronic kidney disease of multifactorial origin affecting tropical countries.

Annals of occupational and environmental medicine

Wimalawansa SA, Wimalawansa SJ.
PMID: 27499855
Ann Occup Environ Med. 2016 Aug 05;28:33. doi: 10.1186/s40557-016-0119-y. eCollection 2016.

BACKGROUND: Environmentally induced, occupational diseases are increasing worldwide, especially in rural agricultural communities. Poverty-associated malnutrition, environmental hazards and pollution, and lack of access to clean water, safe sanitation, and modern healthcare facilities are often associated with these chronic illnesses.METHOD:...

The mechanism of bone resorption by cyclosporin: involvement of the NO-cGMP pathway.

Journal of musculoskeletal & neuronal interactions

Wimalawansa SM, Shankar VS, Simmins DJ, Wimalawansa SJ.
PMID: 15758508
J Musculoskelet Neuronal Interact. 2000 Dec;1(2):141-3.

Treatment with cyclosporin A (CsA) following solid organ transplantations such as heart or liver generally results in bone loss. However, in vitro studies show that CsA inhibits bone resorption. Our previous in vivo animal studies demonstrated that the effects...

Endocrinological Mechanisms of Depressive Disorders and Ill Health.

Expert review of endocrinology & metabolism

Wimalawansa SJ.
PMID: 30063446
Expert Rev Endocrinol Metab. 2016 Jan;11(1):3-6. doi: 10.1586/17446651.2016.1127755. Epub 2016 Jan 06.

No abstract available.

Vitamin D Deficiency: Effects on Oxidative Stress, Epigenetics, Gene Regulation, and Aging.

Biology

Wimalawansa SJ.
PMID: 31083546
Biology (Basel). 2019 May 11;8(2). doi: 10.3390/biology8020030.

Recent advances in vitamin D research indicate that this vitamin, a secosteroid hormone, has beneficial effects on several body systems other than the musculoskeletal system. Both 25 dihydroxy vitamin D [25(OH)

Sensitive and specific radioreceptor assay for calcitonin gene-related Peptide.

Journal of neuroendocrinology

Wimalawansa SJ.
PMID: 19210477
J Neuroendocrinol. 1989 Feb;1(1):15-9. doi: 10.1111/j.1365-2826.1989.tb00071.x.

Abstract Calcitonin gene-related peptide is a 37-amino-acid neuropeptide which has a direct action on the heart and is an extremely potent vasodilator. Immunoreactive calcitonin gene-related peptide is present in plasma, cerebrospinal fluid and in other tissues. We have previously...

Calcitonin Gene-related Peptide (CGRP) is a Mediator of Vascular Adaptations During Hypertension in Pregnancy.

Trends in endocrinology and metabolism: TEM

Yallampalli C, Wimalawansa SJ.
PMID: 18406251
Trends Endocrinol Metab. 1998 Apr;9(3):113-7. doi: 10.1016/s1043-2760(98)00025-3.

Hypertension during pregnancy is a serious obstetrical problem, and the pathophysiology of pre-eclampsia is unclear. Evidence is presented that calcitonin gene-related peptide (CGRP) plays a role in the vascular adaptations that occur during pregnancy. In addition, CGRP might be...

Snapping Extensor Pollicis Longus Tendon Subluxation Secondary to Trapeziometacarpal Instability: Case Report and Technique.

JBJS case connector

Anderson SR, Harrison LM, Wimalawansa SM.
PMID: 33764926
JBJS Case Connect. 2021 Mar 25;11(1). doi: 10.2106/JBJS.CC.20.00478.

CASE: A 20-year-old woman presented with painful, snapping extensor pollicis longus (EPL) tendon subluxation and trapeziometacarpal (TMC) joint instability. Hemi-extensor carpi radialis longus (ECRL) tendon autograft stabilized the TMC joint, reconstructing the 1-2 intermetacarpal ligament. The subluxed EPL tendon...

Calcitonin gene-related peptide reverses the hypertension and significantly decreases the fetal mortality in pre-eclampsia rats induced by NG-nitro-Lmethyl ester.

Human reproduction (Oxford, England)

Yallampalli C, Dong YL, Wimalawansa SJ.
PMID: 8671348
Hum Reprod. 1996 Apr;11(4):895-9.

We recently established that the chronic inhibition of nitric oxide production with NG-nitro-L-arginine methyl ester (L-NAME) increases blood pressure and fetal mortality in pregnant rats. Using this animal model, we have investigated whether calcitonin gene-related peptide (CGRP) can reverse...

Circadian variation of plasma calcitonin gene-related Peptide in man.

Journal of neuroendocrinology

Wimalawansa SJ.
PMID: 19215470
J Neuroendocrinol. 1991 Jun 01;3(3):319-22. doi: 10.1111/j.1365-2826.1991.tb00281.x.

Abstract Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilator peptides known so far. Almost all clinical studies using or measuring CGRP are conducted during the day, and hence this study was carried out to see...

Stigma of obesity: A major barrier to overcome.

Journal of clinical & translational endocrinology

Wimalawansa SJ.
PMID: 29159086
J Clin Transl Endocrinol. 2014 Jun 18;1(3):73-76. doi: 10.1016/j.jcte.2014.06.001. eCollection 2014 Sep.

No abstract available.

Public health interventions for chronic diseases: cost-benefit modelizations for eradicating chronic kidney disease of multifactorial origin (CKDmfo/ CKDu) from tropical countries.

Heliyon

Wimalawansa SJ.
PMID: 31720441
Heliyon. 2019 Nov 01;5(10):e02309. doi: 10.1016/j.heliyon.2019.e02309. eCollection 2019 Oct.

BACKGROUND: In the mid-1970s, an unusual chronic kidney disease of multifactorial origin (CKDmfo), also known as CKD of unknown aetiology (CKDu), began to manifest in several economically poor, tropical, agricultural countries. This preventable, environmentally induced, occupational disease affects several...

Revisiting the Cervicodeltopectoral Flap for Reconstruction of Cutaneous Head and Neck Defects: Technique Description and Clinical Presentation Correlates.

The Journal of craniofacial surgery

Parrish AJ, Anderson SR, Mulenga MA, Wimalawansa SM, Kadakia SP.
PMID: 34292242
J Craniofac Surg. 2021 Jul 20; doi: 10.1097/SCS.0000000000007919. Epub 2021 Jul 20.

STUDY DESIGN: Technique Description with clinical presentation Correlates.PURPOSE: Revisit and discuss the advantages of the cervicodeltopectoral flap (CDP) as an alternative to microvascular reconstruction for head and neck cutaneous defects.METHODS: Retrospective chart review was performed on 2 patients with...

Showing 1 to 12 of 19 entries