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Showing 1 to 12 of 20 entries
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Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Yin Cheung JP, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E.
PMID: 34822786
Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003.

No abstract available.

Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.

Frontiers in neurology

Winsvold BS, Kitsos I, Thomas LF, Skogholt AH, Gabrielsen ME, Zwart JA, Nilsen KB.
PMID: 34975738
Front Neurol. 2021 Dec 17;12:789093. doi: 10.3389/fneur.2021.789093. eCollection 2021.

No abstract available.

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.

Brain : a journal of neurology

Bahrami S, Hindley G, Winsvold BS, O'Connell KS, Frei O, Shadrin A, Cheng W, Bettella F, Rødevand L, Odegaard KJ, Fan CC, Pirinen MJ, Hautakangas HM, Headache HA, Dale AM, Djurovic S, Smeland OB, Andreassen OA.
PMID: 34273149
Brain. 2021 Jul 17; doi: 10.1093/brain/awab267. Epub 2021 Jul 17.

Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are implicated in both. A shared genetic basis to migraine and mental...

Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia.

Pain

Verma V, Drury GL, Parisien M, Özdağ Acarli AN, Al-Aubodah TA, Nijnik A, Wen X, Tugarinov N, Verner M, Klares R, Linton A, Krock E, Morado Urbina CE, Winsvold B, Fritsche LG, Fors EA, Piccirillo C, Khoutorsky A, Svensson CI, Fitzcharles MA, Ingelmo PM, Bernard NF, Dupuy FP, Üçeyler N, Sommer C, King IL, Meloto CB, Diatchenko L.
PMID: 34913882
Pain. 2021 Sep 24; doi: 10.1097/j.pain.0000000000002498. Epub 2021 Sep 24.

ABSTRACT: The pathophysiology of fibromyalgia syndrome (FMS) remains elusive, leading to a lack of objective diagnostic criteria and targeted treatment. We globally evaluated immune system changes in FMS by conducting multiparametric flow cytometry analyses of peripheral blood mononuclear cells...

Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia.

Pain

Verma V, Drury GL, Parisien M, Özdağ Acarli AN, Al-Aubodah TA, Nijnik A, Wen X, Tugarinov N, Verner M, Klares R, Linton A, Krock E, Morado Urbina CE, Winsvold B, Fritsche LG, Fors EA, Piccirillo C, Khoutorsky A, Svensson CI, Fitzcharles MA, Ingelmo PM, Bernard NF, Dupuy FP, Üçeyler N, Sommer C, King IL, Meloto CB, Diatchenko L.
PMID: 34913882
Pain. 2021 Sep 24; doi: 10.1097/j.pain.0000000000002498. Epub 2021 Sep 24.

ABSTRACT: The pathophysiology of fibromyalgia syndrome (FMS) remains elusive, leading to a lack of objective diagnostic criteria and targeted treatment. We globally evaluated immune system changes in FMS by conducting multiparametric flow cytometry analyses of peripheral blood mononuclear cells...

Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study.

Multiple sclerosis journal - experimental, translational and clinical

Gustavsen MW, Celius EG, Winsvold BS, Moen SM, Nygaard GO, Berg-Hansen P, Lie BA, Zwart JA, Harbo HF.
PMID: 28607748
Mult Scler J Exp Transl Clin. 2016 Dec 12;2:2055217316682976. doi: 10.1177/2055217316682976. eCollection 2016.

BACKGROUND: Inconsistent results have been obtained with regard to headache comorbidity in multiple sclerosis (MS).OBJECTIVE: Investigate the one-year prevalence of migraine and tension-type headache (TTH) in Norwegian MS patients and relate this to clinical parameters.METHODS: A questionnaire concerning headache...

Urinary albumin excretion as a marker of endothelial dysfunction in migraine sufferers: the HUNT study, Norway.

BMJ open

Jacobsen LM, Winsvold BS, Romundstad S, Pripp AH, Holmen J, Zwart JA.
PMID: 23943777
BMJ Open. 2013 Aug 13;3(8). doi: 10.1136/bmjopen-2013-003268.

OBJECTIVE: To investigate urine albumin leakage as a marker of endothelial dysfunction in migraine patients.DESIGN: A population-based health study.PARTICIPANTS: 303 patients with migraine, 1009 patients with non-migraine headache and 5287 headache-free controls.OUTCOMES: The association between urine albumin- to-creatine ratio...

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Davey Smith G, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Lee MTM, van Meurs JBJ, Styrkársdóttir U, Zeggini E.
PMID: 34450027
Cell. 2021 Sep 02;184(18):4784-4818.e17. doi: 10.1016/j.cell.2021.07.038. Epub 2021 Aug 26.

Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 osteoarthritis phenotypes, 52 of which have not been associated...

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations.

Cell

Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Yin Cheung JP, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E.
PMID: 34822786
Cell. 2021 Nov 24;184(24):6003-6005. doi: 10.1016/j.cell.2021.11.003.

No abstract available.

Genome-Wide Association Study of 2,093 Cases With Idiopathic Polyneuropathy and 445,256 Controls Identifies First Susceptibility Loci.

Frontiers in neurology

Winsvold BS, Kitsos I, Thomas LF, Skogholt AH, Gabrielsen ME, Zwart JA, Nilsen KB.
PMID: 34975738
Front Neurol. 2021 Dec 17;12:789093. doi: 10.3389/fneur.2021.789093. eCollection 2021.

No abstract available.

Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions.

Brain : a journal of neurology

Khoury S, Parisien M, Thompson SJ, Vachon-Presseau E, Roy M, Martinsen AE, Winsvold BS, Mundal IP, Zwart JA, Kania A, Mogil JS, Diatchenko L.
PMID: 34788396
Brain. 2021 Nov 11; doi: 10.1093/brain/awab359. Epub 2021 Nov 11.

Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is unknown. Using genome-wide approaches, we...

The management and clinical knowledge of headache disorders among general practitioners in Norway: a questionnaire survey.

The journal of headache and pain

Kristoffersen ES, Faiz KW, Hansen JM, Tronvik EA, Frich JC, Lundqvist C, Winsvold BS.
PMID: 34763647
J Headache Pain. 2021 Nov 11;22(1):136. doi: 10.1186/s10194-021-01350-3.

BACKGROUND: General practitioners (GPs) diagnose and manage a majority of headache patients seeking health care. With the aim to understand the potential for clinical improvement and educational needs, we performed a study to investigate Norwegian GPs knowledge about headache...

Showing 1 to 12 of 20 entries