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Showing 1 to 8 of 8 entries
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Recent development of RNAi in drug target discovery and validation.

Drug discovery today. Technologies

Liu G, Wong-Staal F, Li QX.
PMID: 24980531
Drug Discov Today Technol. 2006;3(3):293-300. doi: 10.1016/j.ddtec.2006.09.003.

This article reviews the recent development in two areas of RNAi technology that could potentially shorten the otherwise long process of drug development. First, the combinatorial gene silencing built on the RNAi library, particularly the coming of age of...

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Liu G, Wong-Staal F, Li QX. Recent development of RNAi in drug target discovery and validation. Drug Discov Today Technol. 2006;3(3):293-300doi: 10.1016/j.ddtec.2006.09.003.
Liu, G., Wong-Staal, F., & Li, Q. X. (2006). Recent development of RNAi in drug target discovery and validation. Drug discovery today. Technologies, 3(3), 293-300. https://doi.org/10.1016/j.ddtec.2006.09.003
Liu, Guohong, et al. "Recent development of RNAi in drug target discovery and validation." Drug discovery today. Technologies vol. 3,3 (2006): 293-300. doi: https://doi.org/10.1016/j.ddtec.2006.09.003
Liu G, Wong-Staal F, Li QX. Recent development of RNAi in drug target discovery and validation. Drug Discov Today Technol. 2006;3(3):293-300. doi: 10.1016/j.ddtec.2006.09.003. PMID: 24980531.
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Hybridization of potato spindle tuber viroid to cellular DNA of normal plants.

Proceedings of the National Academy of Sciences of the United States of America

Hadidi A, Jones DM, Gillespie DH, Wong-Staal F, Diener TO.
PMID: 16592335
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2453-7. doi: 10.1073/pnas.73.7.2453.

Molecular hybridization experiments of (125)I-labeled potato spindle tuber viroid (PSTV) with DNA from uninfected or PSTV-infected tomato plants showed that infrequent DNA sequences complementary to PSTV exist in both uninfected and infected cells. DNA titration experiments revealed that at...

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Hadidi A, Jones DM, Gillespie DH, et al. Hybridization of potato spindle tuber viroid to cellular DNA of normal plants. Proc Natl Acad Sci U S A. 1976;73(7):2453-7doi: 10.1073/pnas.73.7.2453.
Hadidi, A., Jones, D. M., Gillespie, D. H., Wong-Staal, F., & Diener, T. O. (1976). Hybridization of potato spindle tuber viroid to cellular DNA of normal plants. Proceedings of the National Academy of Sciences of the United States of America, 73(7), 2453-7. https://doi.org/10.1073/pnas.73.7.2453
Hadidi, A, et al. "Hybridization of potato spindle tuber viroid to cellular DNA of normal plants." Proceedings of the National Academy of Sciences of the United States of America vol. 73,7 (1976): 2453-7. doi: https://doi.org/10.1073/pnas.73.7.2453
Hadidi A, Jones DM, Gillespie DH, Wong-Staal F, Diener TO. Hybridization of potato spindle tuber viroid to cellular DNA of normal plants. Proc Natl Acad Sci U S A. 1976 Jul;73(7):2453-7. doi: 10.1073/pnas.73.7.2453. PMID: 16592335; PMCID: PMC430605.
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Targeting HCV entry for development of therapeutics.

Viruses

Wong-Staal F, Syder AJ, McKelvy JF.
PMID: 21994703
Viruses. 2010 Aug;2(8):1718-33. doi: 10.3390/v2081718. Epub 2010 Aug 18.

Recent progress in defining the molecular mechanisms of Hepatitis C Virus (HCV) entry affords the opportunity to exploit new viral and host targets for therapeutic intervention. Entry inhibitors would limit the expansion of the infected cell reservoir, and would...

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Wong-Staal F, Syder AJ, McKelvy JF. Targeting HCV entry for development of therapeutics. Viruses. 2010;2(8):1718-33doi: 10.3390/v2081718.
Wong-Staal, F., Syder, A. J., & McKelvy, J. F. (2010). Targeting HCV entry for development of therapeutics. Viruses, 2(8), 1718-33. https://doi.org/10.3390/v2081718
Wong-Staal, Flossie, et al. "Targeting HCV entry for development of therapeutics." Viruses vol. 2,8 (2010): 1718-33. doi: https://doi.org/10.3390/v2081718
Wong-Staal F, Syder AJ, McKelvy JF. Targeting HCV entry for development of therapeutics. Viruses. 2010 Aug;2(8):1718-33. doi: 10.3390/v2081718. Epub 2010 Aug 18. PMID: 21994703; PMCID: PMC3185726.
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Maternal inheritance, cytology and macromolecular composition of defective chloroplasts in a variegated mutant of Nicotiana tabacum.

Planta

Wildman SG, Lu-Liao C, Wong-Staal F.
PMID: 24468988
Planta. 1973 Dec;113(4):293-312. doi: 10.1007/BF00387313.

By phase microscopy of living cells the cause of a maternally-inherited variegated, spontaneous mutation of Nicotiana tabacum L. cv. Turkish Samsun was shown to be the presence of defective chloroplasts. These were intermingled with normal chloroplasts in some of...

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Wildman SG, Lu-Liao C, Wong-Staal F. Maternal inheritance, cytology and macromolecular composition of defective chloroplasts in a variegated mutant of Nicotiana tabacum. Planta. 1973;113(4):293-312doi: 10.1007/BF00387313.
Wildman, S. G., Lu-Liao, C., & Wong-Staal, F. (1973). Maternal inheritance, cytology and macromolecular composition of defective chloroplasts in a variegated mutant of Nicotiana tabacum. Planta, 113(4), 293-312. https://doi.org/10.1007/BF00387313
Wildman, S G, et al. "Maternal inheritance, cytology and macromolecular composition of defective chloroplasts in a variegated mutant of Nicotiana tabacum." Planta vol. 113,4 (1973): 293-312. doi: https://doi.org/10.1007/BF00387313
Wildman SG, Lu-Liao C, Wong-Staal F. Maternal inheritance, cytology and macromolecular composition of defective chloroplasts in a variegated mutant of Nicotiana tabacum. Planta. 1973 Dec;113(4):293-312. doi: 10.1007/BF00387313. PMID: 24468988.
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Common site of integration of HTLV in cells of three patients with mature T-cell leukaemia-lymphoma: a retraction.

Nature

Hahn B, Manzari V, Colombini S, Franchini G, Gallo RC, Wong-Staal F.
PMID: 6400697
Nature. 1983 Sep 22-28;305(5932):340. doi: 10.1038/305340a0.

No abstract available.

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Hahn B, Manzari V, Colombini S, et al. Common site of integration of HTLV in cells of three patients with mature T-cell leukaemia-lymphoma: a retraction. Nature. 1983;305(5932):340doi: 10.1038/305340a0.
Hahn, B., Manzari, V., Colombini, S., Franchini, G., Gallo, R. C., & Wong-Staal, F. (1983). Common site of integration of HTLV in cells of three patients with mature T-cell leukaemia-lymphoma: a retraction. Nature, 305(5932), 340. https://doi.org/10.1038/305340a0
Hahn, B, et al. "Common site of integration of HTLV in cells of three patients with mature T-cell leukaemia-lymphoma: a retraction." Nature vol. 305,5932 (1983): 340. doi: https://doi.org/10.1038/305340a0
Hahn B, Manzari V, Colombini S, Franchini G, Gallo RC, Wong-Staal F. Common site of integration of HTLV in cells of three patients with mature T-cell leukaemia-lymphoma: a retraction. Nature. 1983 Sep 22-28;305(5932):340. doi: 10.1038/305340a0. PMID: 6400697.
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A Novel hnRNP Specifically Interacts with HIV-1 RRE RNA.

Journal of biomedical science

Xu Y, Reddy TR, Fischer WH, Wong-Staal F.
PMID: 11725088
J Biomed Sci. 1996 Apr;3(2):82-91. doi: 10.1007/BF02255535.

We have identified and obtained the full-length clone of RREBP49, a human nuclear factor which specifically interacts with the Rev-responsive element (RRE) sequence of human immunodeficiency virus type 1. Sequence analysis revealed that RREBP49 is highly homologous to hnRNP...

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Xu Y, Reddy TR, Fischer WH, et al. A Novel hnRNP Specifically Interacts with HIV-1 RRE RNA. J Biomed Sci. 1996;3(2):82-91doi: 10.1007/BF02255535.
Xu, Y., Reddy, T. R., Fischer, W. H., & Wong-Staal, F. (1996). A Novel hnRNP Specifically Interacts with HIV-1 RRE RNA. Journal of biomedical science, 3(2), 82-91. https://doi.org/10.1007/BF02255535
Xu, Y., et al. "A Novel hnRNP Specifically Interacts with HIV-1 RRE RNA." Journal of biomedical science vol. 3,2 (1996): 82-91. doi: https://doi.org/10.1007/BF02255535
Xu Y, Reddy TR, Fischer WH, Wong-Staal F. A Novel hnRNP Specifically Interacts with HIV-1 RRE RNA. J Biomed Sci. 1996 Apr;3(2):82-91. doi: 10.1007/BF02255535. PMID: 11725088.
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Hormone Receptor Regulation of the Human Immunodeficiency Virus Type 1 and Type 2 Long Terminal Repeats.

Journal of biomedical science

Xu J, Luznik L, Wong-Staal F, Gill GN.
PMID: 11725114
J Biomed Sci. 1996 Sep-Oct;3(5):323-331. doi: 10.1007/BF02257962.

Both host cell and viral transcription factors regulate the long terminal repeat (LTR) of human immuno-deficiency virus (HIV) activity and viral replication. Using transient transfection, ligand-activated thyroid hormone and 9-cis-retinoic acid receptors (T(3)R and RXR) were found to stimulate...

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Xu J, Luznik L, Wong-Staal F, et al. Hormone Receptor Regulation of the Human Immunodeficiency Virus Type 1 and Type 2 Long Terminal Repeats. J Biomed Sci. 1996;3(5):323-331doi: 10.1007/BF02257962.
Xu, J., Luznik, L., Wong-Staal, F., & Gill, G. N. (1996). Hormone Receptor Regulation of the Human Immunodeficiency Virus Type 1 and Type 2 Long Terminal Repeats. Journal of biomedical science, 3(5), 323-331. https://doi.org/10.1007/BF02257962
Xu, J., et al. "Hormone Receptor Regulation of the Human Immunodeficiency Virus Type 1 and Type 2 Long Terminal Repeats." Journal of biomedical science vol. 3,5 (1996): 323-331. doi: https://doi.org/10.1007/BF02257962
Xu J, Luznik L, Wong-Staal F, Gill GN. Hormone Receptor Regulation of the Human Immunodeficiency Virus Type 1 and Type 2 Long Terminal Repeats. J Biomed Sci. 1996 Sep-Oct;3(5):323-331. doi: 10.1007/BF02257962. PMID: 11725114.
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Identification of a mutation in chloroplast DNA correlated with formation of defective chloroplasts in a variegated mutant of Nicotiana tabacum.

Planta

Wong-Staal F, Wildman SG.
PMID: 24468989
Planta. 1973 Dec;113(4):313-26. doi: 10.1007/BF00387314.

As in wild-type Nicotiana tabacum L., two satellite DNAs having densities of 1.700 and 1.705 g cm(-3) in CsCl were identified in the organelle fraction of homogenates made from variegated leaves of a cytoplasmic mutant of N. tabacum. As...

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Wong-Staal F, Wildman SG. Identification of a mutation in chloroplast DNA correlated with formation of defective chloroplasts in a variegated mutant of Nicotiana tabacum. Planta. 1973;113(4):313-26doi: 10.1007/BF00387314.
Wong-Staal, F., & Wildman, S. G. (1973). Identification of a mutation in chloroplast DNA correlated with formation of defective chloroplasts in a variegated mutant of Nicotiana tabacum. Planta, 113(4), 313-26. https://doi.org/10.1007/BF00387314
Wong-Staal, F, and Wildman, S G. "Identification of a mutation in chloroplast DNA correlated with formation of defective chloroplasts in a variegated mutant of Nicotiana tabacum." Planta vol. 113,4 (1973): 313-26. doi: https://doi.org/10.1007/BF00387314
Wong-Staal F, Wildman SG. Identification of a mutation in chloroplast DNA correlated with formation of defective chloroplasts in a variegated mutant of Nicotiana tabacum. Planta. 1973 Dec;113(4):313-26. doi: 10.1007/BF00387314. PMID: 24468989.
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Showing 1 to 8 of 8 entries