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Showing 1 to 12 of 42 entries
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Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease.

Ophthalmology. Retina

Knickelbein JE, Jacobs-El N, Wong WT, Wiley HE, Cukras CA, Meyerle CB, Chew EY.
PMID: 28670632
Ophthalmol Retina. 2017 May-Jun;1(3):181-187. doi: 10.1016/j.oret.2016.10.007.

PURPOSE: To describe the clinical course of advanced juxtapapillary retinal capillary hemangioblastomas (RCH) associated with von Hippel-Lindau (VHL) disease treated with systemic sunitinib malate, an agent that inhibits both anti-vascular endothelial growth factor and anti-platelet-derived growth factor signaling.DESIGN: Observational...

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Knickelbein JE, Jacobs-El N, Wong WT, et al. Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease. Ophthalmol Retina. 2017;1(3):181-187doi: 10.1016/j.oret.2016.10.007.
Knickelbein, J. E., Jacobs-El, N., Wong, W. T., Wiley, H. E., Cukras, C. A., Meyerle, C. B., & Chew, E. Y. (2017). Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease. Ophthalmology. Retina, 1(3), 181-187. https://doi.org/10.1016/j.oret.2016.10.007
Knickelbein, Jared E, et al. "Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease." Ophthalmology. Retina vol. 1,3 (2017): 181-187. doi: https://doi.org/10.1016/j.oret.2016.10.007
Knickelbein JE, Jacobs-El N, Wong WT, Wiley HE, Cukras CA, Meyerle CB, Chew EY. Systemic Sunitinib Malate Treatment for Advanced Juxtapapillary Retinal Hemangioblastomas Associated with von Hippel-Lindau Disease. Ophthalmol Retina. 2017 May-Jun;1(3):181-187. doi: 10.1016/j.oret.2016.10.007. PMID: 28670632; PMCID: PMC5490440.
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Base-catalyzed halogen dance reaction and oxidative coupling sequence as a convenient method for the preparation of dihalo-bisheteroarenes.

Organic letters

Getmanenko YA, Tongwa P, Timofeeva TV, Marder SR.
PMID: 20377230
Org Lett. 2010 May 07;12(9):2136-9. doi: 10.1021/ol1006423.

A one-pot preparation of the 2,2'-dibromo-1,1'-bisheteroarenes 3a-d from bromo-heteroarenes utilizing the sequence of the base-catalyzed halogen dance (BCHD) reaction and CuCl(2)-promoted oxidative coupling of the in situ formed alpha-lithio-beta-halo-heteroarenes 2a-d provides a convenient access to precursors for the preparation...

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Getmanenko YA, Tongwa P, Timofeeva TV, et al. Base-catalyzed halogen dance reaction and oxidative coupling sequence as a convenient method for the preparation of dihalo-bisheteroarenes. Org Lett. 2010;12(9):2136-9doi: 10.1021/ol1006423.
Getmanenko, Y. A., Tongwa, P., Timofeeva, T. V., & Marder, S. R. (2010). Base-catalyzed halogen dance reaction and oxidative coupling sequence as a convenient method for the preparation of dihalo-bisheteroarenes. Organic letters, 12(9), 2136-9. https://doi.org/10.1021/ol1006423
Getmanenko, Yulia A, et al. "Base-catalyzed halogen dance reaction and oxidative coupling sequence as a convenient method for the preparation of dihalo-bisheteroarenes." Organic letters vol. 12,9 (2010): 2136-9. doi: https://doi.org/10.1021/ol1006423
Getmanenko YA, Tongwa P, Timofeeva TV, Marder SR. Base-catalyzed halogen dance reaction and oxidative coupling sequence as a convenient method for the preparation of dihalo-bisheteroarenes. Org Lett. 2010 May 07;12(9):2136-9. doi: 10.1021/ol1006423. PMID: 20377230.
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Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater.

Frontiers in physiology

Ching B, Chen XL, Yong JH, Wilson JM, Hiong KC, Sim EW, Wong WP, Lam SH, Chew SF, Ip YK.
PMID: 23760020
Front Physiol. 2013 Jun 07;4:135. doi: 10.3389/fphys.2013.00135. eCollection 2013.

This study aimed to test the hypothesis that branchial osmoregulatory acclimation involved increased apoptosis and replacement of mitochdonrion-rich cells (MRCs) in the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater. A significant increase in branchial...

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Ching B, Chen XL, Yong JH, et al. Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater. Front Physiol. 2013;4:135doi: 10.3389/fphys.2013.00135.
Ching, B., Chen, X. L., Yong, J. H., Wilson, J. M., Hiong, K. C., Sim, E. W., Wong, W. P., Lam, S. H., Chew, S. F., & Ip, Y. K. (2013). Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater. Frontiers in physiology, 4135. https://doi.org/10.3389/fphys.2013.00135
Ching, Biyun, et al. "Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater." Frontiers in physiology vol. 4 (2013): 135. doi: https://doi.org/10.3389/fphys.2013.00135
Ching B, Chen XL, Yong JH, Wilson JM, Hiong KC, Sim EW, Wong WP, Lam SH, Chew SF, Ip YK. Increases in apoptosis, caspase activity and expression of p53 and bax, and the transition between two types of mitochondrion-rich cells, in the gills of the climbing perch, Anabas testudineus, during a progressive acclimation from freshwater to seawater. Front Physiol. 2013 Jun 07;4:135. doi: 10.3389/fphys.2013.00135. eCollection 2013. PMID: 23760020; PMCID: PMC3675322.
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Luminescent Fluorene-Based Bis-Pyrazolyl Aniline Ligand for Aluminum Detection.

Journal of fluorescence

Frazer A, Morales AR, Woodward AW, Tongwa P, Timofeeva T, Belfield KD.
PMID: 24078297
J Fluoresc. 2013 Sep 29; doi: 10.1007/s10895-013-1291-x. Epub 2013 Sep 29.

The design, synthesis, and photophysical properties of a new fluorene-based fluorescent chemosensor, 4-((E)-2-(2-(benzo[d]thiazol-2-yl)-9,9-diethyl-9H-fluoren-7-yl)vinyl)-N,N-bis((3,5-dimethyl-1H-pyrazol-1-yl)methyl)benzenamine (AXF-Al), is described for the detection of Al

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Frazer A, Morales AR, Woodward AW, et al. Luminescent Fluorene-Based Bis-Pyrazolyl Aniline Ligand for Aluminum Detection. J Fluoresc. 2013;doi: 10.1007/s10895-013-1291-x.
Frazer, A., Morales, A. R., Woodward, A. W., Tongwa, P., Timofeeva, T., & Belfield, K. D. (2013). Luminescent Fluorene-Based Bis-Pyrazolyl Aniline Ligand for Aluminum Detection. Journal of fluorescence, . https://doi.org/10.1007/s10895-013-1291-x
Frazer, Andrew, et al. "Luminescent Fluorene-Based Bis-Pyrazolyl Aniline Ligand for Aluminum Detection." Journal of fluorescence vol. (2013). doi: https://doi.org/10.1007/s10895-013-1291-x
Frazer A, Morales AR, Woodward AW, Tongwa P, Timofeeva T, Belfield KD. Luminescent Fluorene-Based Bis-Pyrazolyl Aniline Ligand for Aluminum Detection. J Fluoresc. 2013 Sep 29; doi: 10.1007/s10895-013-1291-x. Epub 2013 Sep 29. PMID: 24078297.
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Corneal Refractive Procedures for the Treatment of Presbyopia.

The open ophthalmology journal

Moussa K, Jehangir N, Mannis T, Wong WL, Moshirfar M.
PMID: 28553423
Open Ophthalmol J. 2017 Apr 27;11:59-75. doi: 10.2174/1874364101711010059. eCollection 2017.

PURPOSE: Refractive surgery has been in use for a long time and is evolving at a fast pace with several new corneal procedures being used for the correction of presbyopia. The purpose of this article is to give a...

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Moussa K, Jehangir N, Mannis T, et al. Corneal Refractive Procedures for the Treatment of Presbyopia. Open Ophthalmol J. 2017;11:59-75doi: 10.2174/1874364101711010059.
Moussa, K., Jehangir, N., Mannis, T., Wong, W. L., & Moshirfar, M. (2017). Corneal Refractive Procedures for the Treatment of Presbyopia. The open ophthalmology journal, 1159-75. https://doi.org/10.2174/1874364101711010059
Moussa, Kareem, et al. "Corneal Refractive Procedures for the Treatment of Presbyopia." The open ophthalmology journal vol. 11 (2017): 59-75. doi: https://doi.org/10.2174/1874364101711010059
Moussa K, Jehangir N, Mannis T, Wong WL, Moshirfar M. Corneal Refractive Procedures for the Treatment of Presbyopia. Open Ophthalmol J. 2017 Apr 27;11:59-75. doi: 10.2174/1874364101711010059. eCollection 2017. PMID: 28553423; PMCID: PMC5427700.
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Na.

Frontiers in physiology

Chen XL, Zhang B, Chng YR, Ong JLY, Chew SF, Wong WP, Lam SH, Ip YK.
PMID: 29209224
Front Physiol. 2017 Nov 02;8:880. doi: 10.3389/fphys.2017.00880. eCollection 2017.

The freshwater climbing perch,

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Chen XL, Zhang B, Chng YR, et al. Na. Front Physiol. 2017;8:880doi: 10.3389/fphys.2017.00880.
Chen, X. L., Zhang, B., Chng, Y. R., Ong, J. L. Y., Chew, S. F., Wong, W. P., Lam, S. H., & Ip, Y. K. (2017). Na. Frontiers in physiology, 8880. https://doi.org/10.3389/fphys.2017.00880
Chen, Xiu L, et al. "Na." Frontiers in physiology vol. 8 (2017): 880. doi: https://doi.org/10.3389/fphys.2017.00880
Chen XL, Zhang B, Chng YR, Ong JLY, Chew SF, Wong WP, Lam SH, Ip YK. Na. Front Physiol. 2017 Nov 02;8:880. doi: 10.3389/fphys.2017.00880. eCollection 2017. PMID: 29209224; PMCID: PMC5701670.
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Fundus autofluorescence patterns in stargardt disease over time-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)

Cukras CA, Wong WT, Caruso R, Cunningham D, Zein W, Sieving P.
PMID: 23753838
Arch Ophthalmol. 2012 Oct;130(10):1354-5. doi: 10.1001/archophthalmol.2012.2008.

No abstract available.

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Cukras CA, Wong WT, Caruso R, et al. Fundus autofluorescence patterns in stargardt disease over time-reply. Arch Ophthalmol. 2012;130(10):1354-5doi: 10.1001/archophthalmol.2012.2008.
Cukras, C. A., Wong, W. T., Caruso, R., Cunningham, D., Zein, W., & Sieving, P. (2012). Fundus autofluorescence patterns in stargardt disease over time-reply. Archives of ophthalmology (Chicago, Ill. : 1960), 130(10), 1354-5. https://doi.org/10.1001/archophthalmol.2012.2008
Cukras, Catherine A, et al. "Fundus autofluorescence patterns in stargardt disease over time-reply." Archives of ophthalmology (Chicago, Ill. : 1960) vol. 130,10 (2012): 1354-5. doi: https://doi.org/10.1001/archophthalmol.2012.2008
Cukras CA, Wong WT, Caruso R, Cunningham D, Zein W, Sieving P. Fundus autofluorescence patterns in stargardt disease over time-reply. Arch Ophthalmol. 2012 Oct;130(10):1354-5. doi: 10.1001/archophthalmol.2012.2008. PMID: 23753838; PMCID: PMC8409255.
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Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study.

Translational vision science & technology

Valent DJ, Wong WT, Chew EY, Cukras CA.
PMID: 30584490
Transl Vis Sci Technol. 2018 Dec 17;7(6):24. doi: 10.1167/tvst.7.6.24. eCollection 2018 Nov.

PURPOSE: The activation of microglia, the primary innate immune cell resident in the retina, produces inflammatory mediators, which underlie changes in diabetic retinopathy including increased vascular permeability. This study evaluates the safety and efficacy of dextromethorphan, a drug capable...

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Valent DJ, Wong WT, Chew EY, et al. Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study. Transl Vis Sci Technol. 2018;7(6):24doi: 10.1167/tvst.7.6.24.
Valent, D. J., Wong, W. T., Chew, E. Y., & Cukras, C. A. (2018). Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study. Translational vision science & technology, 7(6), 24. https://doi.org/10.1167/tvst.7.6.24
Valent, David J, et al. "Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study." Translational vision science & technology vol. 7,6 (2018): 24. doi: https://doi.org/10.1167/tvst.7.6.24
Valent DJ, Wong WT, Chew EY, Cukras CA. Oral Dextromethorphan for the Treatment of Diabetic Macular Edema: Results From a Phase I/II Clinical Study. Transl Vis Sci Technol. 2018 Dec 17;7(6):24. doi: 10.1167/tvst.7.6.24. eCollection 2018 Nov. PMID: 30584490; PMCID: PMC6300336.
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The microglia response to electrical overstimulation of the retina imaged under a transparent stimulus electrode.

Journal of neural engineering

Yohannes AR, Jung CY, Shea KI, Wong WT, Beylin A, Cohen ED.
PMID: 33418555
J Neural Eng. 2021 Jan 08; doi: 10.1088/1741-2552/abda0a. Epub 2021 Jan 08.

OBJECTIVE: We investigated using the morphological response of retinal microglia as indicators of tissue damage from electrical overstimulation by imaging them through an optically transparent stimulus electrode.APPROACH: To track the microglia, we used a transgenic mouse where the microglia...

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Yohannes AR, Jung CY, Shea KI, et al. The microglia response to electrical overstimulation of the retina imaged under a transparent stimulus electrode. J Neural Eng. 2021;doi: 10.1088/1741-2552/abda0a.
Yohannes, A. R., Jung, C. Y., Shea, K. I., Wong, W. T., Beylin, A., & Cohen, E. D. (2021). The microglia response to electrical overstimulation of the retina imaged under a transparent stimulus electrode. Journal of neural engineering, . https://doi.org/10.1088/1741-2552/abda0a
Yohannes, Alula R, et al. "The microglia response to electrical overstimulation of the retina imaged under a transparent stimulus electrode." Journal of neural engineering vol. (2021). doi: https://doi.org/10.1088/1741-2552/abda0a
Yohannes AR, Jung CY, Shea KI, Wong WT, Beylin A, Cohen ED. The microglia response to electrical overstimulation of the retina imaged under a transparent stimulus electrode. J Neural Eng. 2021 Jan 08; doi: 10.1088/1741-2552/abda0a. Epub 2021 Jan 08. PMID: 33418555.
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Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT.

Ophthalmology. Retina

Pasricha MV, Tai V, Sleiman K, Winter K, Chiu SJ, Farsiu S, Stinnett SS, Lad EM, Wong WT, Chew EY, Toth CA.
PMID: 33348086
Ophthalmol Retina. 2021 May;5(5):396-408. doi: 10.1016/j.oret.2020.12.010. Epub 2020 Dec 22.

PURPOSE: In macula-wide analyses, spectral-domain (SD) optical coherence tomography (OCT) features including drusen volume, hyperreflective foci, and OCT-reflective drusen substructures independently predict geographic atrophy (GA) onset secondary to age-related macular degeneration (AMD). We sought to identify SD OCT features...

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Pasricha MV, Tai V, Sleiman K, et al. Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT. Ophthalmol Retina. 2020;5(5):396-408doi: 10.1016/j.oret.2020.12.010.
Pasricha, M. V., Tai, V., Sleiman, K., Winter, K., Chiu, S. J., Farsiu, S., Stinnett, S. S., Lad, E. M., Wong, W. T., Chew, E. Y., Toth, C. A. (2021). Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT. Ophthalmology. Retina, 5(5), 396-408. https://doi.org/10.1016/j.oret.2020.12.010
Pasricha, Malini Veerappan, et al. "Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT." Ophthalmology. Retina vol. 5,5 (2021): 396-408. doi: https://doi.org/10.1016/j.oret.2020.12.010
Pasricha MV, Tai V, Sleiman K, Winter K, Chiu SJ, Farsiu S, Stinnett SS, Lad EM, Wong WT, Chew EY, Toth CA. Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT. Ophthalmol Retina. 2021 May;5(5):396-408. doi: 10.1016/j.oret.2020.12.010. Epub 2020 Dec 22. PMID: 33348086; PMCID: PMC8362836.
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The Whitish Inner Mantle of the Giant Clam, .

Frontiers in physiology

Ip YK, Hiong KC, Goh EJK, Boo MV, Choo CYL, Ching B, Wong WP, Chew SF.
PMID: 29066980
Front Physiol. 2017 Oct 10;8:781. doi: 10.3389/fphys.2017.00781. eCollection 2017.

Giant clams live in symbiosis with extracellular zooxanthellae and display high rates of growth and shell formation (calcification) in light. Light-enhanced calcification requires an increase in the supply of Ca

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Ip YK, Hiong KC, Goh EJK, et al. The Whitish Inner Mantle of the Giant Clam, . Front Physiol. 2017;8:781doi: 10.3389/fphys.2017.00781.
Ip, Y. K., Hiong, K. C., Goh, E. J. K., Boo, M. V., Choo, C. Y. L., Ching, B., Wong, W. P., & Chew, S. F. (2017). The Whitish Inner Mantle of the Giant Clam, . Frontiers in physiology, 8781. https://doi.org/10.3389/fphys.2017.00781
Ip, Yuen K, et al. "The Whitish Inner Mantle of the Giant Clam, ." Frontiers in physiology vol. 8 (2017): 781. doi: https://doi.org/10.3389/fphys.2017.00781
Ip YK, Hiong KC, Goh EJK, Boo MV, Choo CYL, Ching B, Wong WP, Chew SF. The Whitish Inner Mantle of the Giant Clam, . Front Physiol. 2017 Oct 10;8:781. doi: 10.3389/fphys.2017.00781. eCollection 2017. PMID: 29066980; PMCID: PMC5641333.
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Effects of protein hydrolysate from chicken feather meal on tyrosinase activity and melanin formation in B16F10 murine melanoma cells.

Food science and biotechnology

Pongkai P, Saisavoey T, Sangtanoo P, Sangvanich P, Karnchanatat A.
PMID: 30263653
Food Sci Biotechnol. 2017 Aug 18;26(5):1199-1208. doi: 10.1007/s10068-017-0186-z. eCollection 2017.

Tyrosinase is a copper-containing enzyme that controls mammalian melanogenesis. Tyrosinase inhibitors are important for their potential application in cosmetic products. Chicken feather meal is a rich source of amino acids, which have been linked with tyrosinase inhibition activity. This...

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Pongkai P, Saisavoey T, Sangtanoo P, et al. Effects of protein hydrolysate from chicken feather meal on tyrosinase activity and melanin formation in B16F10 murine melanoma cells. Food Sci Biotechnol. 2017;26(5):1199-1208doi: 10.1007/s10068-017-0186-z.
Pongkai, P., Saisavoey, T., Sangtanoo, P., Sangvanich, P., & Karnchanatat, A. (2017). Effects of protein hydrolysate from chicken feather meal on tyrosinase activity and melanin formation in B16F10 murine melanoma cells. Food science and biotechnology, 26(5), 1199-1208. https://doi.org/10.1007/s10068-017-0186-z
Pongkai, Puttaporn, et al. "Effects of protein hydrolysate from chicken feather meal on tyrosinase activity and melanin formation in B16F10 murine melanoma cells." Food science and biotechnology vol. 26,5 (2017): 1199-1208. doi: https://doi.org/10.1007/s10068-017-0186-z
Pongkai P, Saisavoey T, Sangtanoo P, Sangvanich P, Karnchanatat A. Effects of protein hydrolysate from chicken feather meal on tyrosinase activity and melanin formation in B16F10 murine melanoma cells. Food Sci Biotechnol. 2017 Aug 18;26(5):1199-1208. doi: 10.1007/s10068-017-0186-z. eCollection 2017. PMID: 30263653; PMCID: PMC6049799.
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Showing 1 to 12 of 42 entries