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Showing 1 to 12 of 248 entries
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Understanding the spectrum of haemophagocytic lymphohistiocytosis: update on diagnostic challenges and therapeutic options.

British journal of haematology

Brisse E, Matthys P, Wouters CH.
PMID: 27292929
Br J Haematol. 2016 Jul;174(2):175-87. doi: 10.1111/bjh.14144. Epub 2016 Jun 12.

The cytokine storm syndrome 'haemophagocytic lymphohistiocytosis' (HLH) is an under-recognized hyperinflammatory disorder, causing high morbidity and mortality risk in children and adults. It can be subdivided into a primary, genetic form and a secondary, acquired form that complicates diverse...

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the .

Journal of Cancer

Van den Bossche J, Deben C, Op de Beeck K, Deschoolmeester V, Hermans C, De Pauw I, Jacobs J, Van Schil P, Vermorken JB, Pauwels P, Peeters M, Lardon F, Wouters A.
PMID: 28638459
J Cancer. 2017 May 12;8(8):1441-1452. doi: 10.7150/jca.18455. eCollection 2017.

No abstract available.

Measurement properties of the Timed Up & Go test in patients with COPD.

Chronic respiratory disease

Mesquita R, Wilke S, Smid DE, Janssen DJ, Franssen FM, Probst VS, Wouters EF, Muris JW, Pitta F, Spruit MA.
PMID: 27165963
Chron Respir Dis. 2016 Nov;13(4):344-352. doi: 10.1177/1479972316647178. Epub 2016 Jul 08.

We aimed to investigate the construct validity of the Timed Up & Go (TUG) test in chronic obstructive pulmonary disease (COPD), to identify characteristics related to an abnormal TUG time and to examine the responsiveness of the TUG to...

Central 5-HT2 antagonists: A preclinical evaluation of a therapeutic potential.

Acta neuropsychiatrica

Meert TF, Awouters F.
PMID: 26952556
Acta Neuropsychiatr. 1990 Dec;2(4):101-9. doi: 10.1017/S0924270800034517.

A preclinical evaluation is presented of the serotonin 5-HT2 antagonists ritanserin and risperidone. Whereas ritanserin is a relative selective 5-HT2 antagonist, risperidone is a potent 5-HT2 and catecholamine antagonist. The pharmacological differences between both drugs are also observed in...

Cathepsin B launches an apoptotic exit effort upon cell death-associated disruption of lysosomes.

Cell death discovery

de Castro MA, Bunt G, Wouters FS.
PMID: 27551506
Cell Death Discov. 2016 Feb 29;2:16012. doi: 10.1038/cddiscovery.2016.12. eCollection 2016.

The release of cathepsin proteases from disrupted lysosomes results in lethal cellular autodigestion. Lysosomal disruption-related cell death is highly variable, showing both apoptotic and necrotic outcomes. As the substrate spectrum of lysosomal proteases encompasses the apoptosis-regulating proteins of the...

Exploring Innovative Solutions for Quality of Life and Care of Bed-Ridden Nursing Home Residents through Codesign Sessions.

Journal of aging research

van Hoof J, Wetzels MH, Dooremalen AM, Overdiep RA, Nieboer ME, Eyck AM, van Gorkom PJ, Zwerts-Verhelst EL, Aarts S, Vissers-Luijcks C, van der Voort CS, Moonen MJ, van de Vrande HA, van Dijck-Heinen CJ, Wouters EJ.
PMID: 26543647
J Aging Res. 2015;2015:185054. doi: 10.1155/2015/185054. Epub 2015 Oct 12.

Bed-ridden nursing home residents are in need of environments which are homelike and facilitate the provision of care. Design guidance for this group of older people is limited. This study concerned the exploration and generation of innovative environmental enrichment...

The Factors Influencing the Sense of Home in Nursing Homes: A Systematic Review from the Perspective of Residents.

Journal of aging research

Rijnaard MD, van Hoof J, Janssen BM, Verbeek H, Pocornie W, Eijkelenboom A, Beerens HC, Molony SL, Wouters EJ.
PMID: 27313892
J Aging Res. 2016;2016:6143645. doi: 10.1155/2016/6143645. Epub 2016 May 23.

Purpose. To provide an overview of factors influencing the sense of home of older adults residing in the nursing home. Methods. A systematic review was conducted. Inclusion criteria were (1) original and peer-reviewed research, (2) qualitative, quantitative, or mixed...

COPD and exercise: does it make a difference?.

Breathe (Sheffield, England)

Spruit MA, Burtin C, De Boever P, Langer D, Vogiatzis I, Wouters EF, Franssen FM.
PMID: 27408645
Breathe (Sheff). 2016 Jun;12(2):e38-49. doi: 10.1183/20734735.003916.

KEY POINTS: Physiological changes are observed following a structured exercise training programme in patients with COPD, without changes in resting lung function.Exercise training is the cornerstone of a comprehensive pulmonary rehabilitation programme in patients with COPD.Most comorbidities in patients...

Some pharmacokinetics of sevoflurane in a child with severe lipodystrophy.

A & A case reports

Steen ER, De Baerdemaeker LE, Van Limmen J, Wouters P.
PMID: 25611541
A A Case Rep. 2014 Mar 15;2(6):61-4. doi: 10.1097/ACC.0b013e3182a706f6.

Lipodystrophies are acquired or inherited disorders characterized in part by the selective loss of adipose tissue and hypertriglyceridemia. The present case report of 2 sevoflurane anesthetics given to a child with such a disorder, before and after correction of...

Isolation of EST-derived microsatellite markers for genotyping the A and B genomes of wheat.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Eujayl I, Sorrells ME, Baum M, Wolters P, Powell W.
PMID: 12582712
Theor Appl Genet. 2002 Feb;104(2):399-407. doi: 10.1007/s001220100738.

Genetic variation present in 64 durum wheat accessions was investigated by using three sources of microsatellite (SSR) markers: EST-derived SSRs (EST-SSRs) and two sources of SSRs isolated from total genomic DNA. Out of 245 SSR primer pairs screened, 22...

New perspectives for an old cure: a glucose-insulin-potassium revival in cardiac surgery?.

Current opinion in anaesthesiology

Wouters PF.
PMID: 17021526
Curr Opin Anaesthesiol. 2004 Feb;17(1):31-3. doi: 10.1097/00001503-200402000-00006.

No abstract available.

Nutritional considerations in the treatment of chronic obstructive pulmonary disease.

Clinical nutrition (Edinburgh, Scotland)

Schols AM, Wouters EF.
PMID: 16843903
Clin Nutr. 1995 Apr;14(2):64-73. doi: 10.1016/s0261-5614(95)80025-5.

No abstract available.

Showing 1 to 12 of 248 entries