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Design, Synthesis and Anticandidal Evaluation of Indazole and Pyrazole Derivatives.

Pharmaceuticals (Basel, Switzerland)

Rodríguez-Villar K, Hernández-Campos A, Yépez-Mulia L, Sainz-Espuñes TDR, Soria-Arteche O, Palacios-Espinosa JF, Cortés-Benítez F, Leyte-Lugo M, Varela-Petrissans B, Quintana-Salazar EA, Pérez-Villanueva J.
PMID: 33668364
Pharmaceuticals (Basel). 2021 Feb 24;14(3). doi: 10.3390/ph14030176.

Candidiasis, caused by yeasts of the genus Candida, is the second cause of superficial and mucosal infections and the fourth cause of bloodstream infections. Although some antifungal drugs to treat candidiasis are available, resistant strains to current therapies are...

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Rodríguez-Villar K, Hernández-Campos A, Yépez-Mulia L, et al. Design, Synthesis and Anticandidal Evaluation of Indazole and Pyrazole Derivatives. Pharmaceuticals (Basel). 2021;14(3)doi: 10.3390/ph14030176.
Rodríguez-Villar, K., Hernández-Campos, A., Yépez-Mulia, L., Sainz-Espuñes, T. D. R., Soria-Arteche, O., Palacios-Espinosa, J. F., Cortés-Benítez, F., Leyte-Lugo, M., Varela-Petrissans, B., Quintana-Salazar, E. A., & Pérez-Villanueva, J. (2021). Design, Synthesis and Anticandidal Evaluation of Indazole and Pyrazole Derivatives. Pharmaceuticals (Basel, Switzerland), 14(3), . https://doi.org/10.3390/ph14030176
Rodríguez-Villar, Karen, et al. "Design, Synthesis and Anticandidal Evaluation of Indazole and Pyrazole Derivatives." Pharmaceuticals (Basel, Switzerland) vol. 14,3 (2021). doi: https://doi.org/10.3390/ph14030176
Rodríguez-Villar K, Hernández-Campos A, Yépez-Mulia L, Sainz-Espuñes TDR, Soria-Arteche O, Palacios-Espinosa JF, Cortés-Benítez F, Leyte-Lugo M, Varela-Petrissans B, Quintana-Salazar EA, Pérez-Villanueva J. Design, Synthesis and Anticandidal Evaluation of Indazole and Pyrazole Derivatives. Pharmaceuticals (Basel). 2021 Feb 24;14(3). doi: 10.3390/ph14030176. PMID: 33668364; PMCID: PMC7996157.
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Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2.

Pharmaceuticals (Basel, Switzerland)

Pérez-Villanueva J, Matadamas-Martínez F, Yépez-Mulia L, Pérez-Koldenkova V, Leyte-Lugo M, Rodríguez-Villar K, Cortés-Benítez F, Macías-Jiménez AP, González-Sánchez I, Romero-Velásquez A, Palacios-Espinosa JF, Soria-Arteche O.
PMID: 34451912
Pharmaceuticals (Basel). 2021 Aug 19;14(8). doi: 10.3390/ph14080815.

Cancer is the second leading cause of death, after cardiovascular diseases. Different strategies have been developed to treat cancer; however, chemotherapy with cytotoxic agents is still the most widely used treatment approach. Nevertheless, drug resistance to available chemotherapeutic agents...

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Pérez-Villanueva J, Matadamas-Martínez F, Yépez-Mulia L, et al. Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2. Pharmaceuticals (Basel). 2021;14(8)doi: 10.3390/ph14080815.
Pérez-Villanueva, J., Matadamas-Martínez, F., Yépez-Mulia, L., Pérez-Koldenkova, V., Leyte-Lugo, M., Rodríguez-Villar, K., Cortés-Benítez, F., Macías-Jiménez, A. P., González-Sánchez, I., Romero-Velásquez, A., Palacios-Espinosa, J. F., & Soria-Arteche, O. (2021). Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2. Pharmaceuticals (Basel, Switzerland), 14(8), . https://doi.org/10.3390/ph14080815
Pérez-Villanueva, Jaime, et al. "Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2." Pharmaceuticals (Basel, Switzerland) vol. 14,8 (2021). doi: https://doi.org/10.3390/ph14080815
Pérez-Villanueva J, Matadamas-Martínez F, Yépez-Mulia L, Pérez-Koldenkova V, Leyte-Lugo M, Rodríguez-Villar K, Cortés-Benítez F, Macías-Jiménez AP, González-Sánchez I, Romero-Velásquez A, Palacios-Espinosa JF, Soria-Arteche O. Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2. Pharmaceuticals (Basel). 2021 Aug 19;14(8). doi: 10.3390/ph14080815. PMID: 34451912; PMCID: PMC8401203.
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In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México.

Bioorganic & medicinal chemistry

Domínguez-Díaz LR, Eugenia Ochoa M, Soto-Castro D, Farfán N, Morales-Chamorro M, Yépez-Mulia L, Pérez-Campos E, Santillan R, Moreno-Rodríguez A.
PMID: 34571489
Bioorg Med Chem. 2021 Oct 15;48:116417. doi: 10.1016/j.bmc.2021.116417. Epub 2021 Sep 20.

Chagas disease is a health problem that affects millions of persons, currently Nifurtimox (Nfx) and Benznidazole (Bz) are the unique drugs to treat it. However, these drugs produce adverse effects and high toxicity, which has motivated the search for...

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Domínguez-Díaz LR, Eugenia Ochoa M, Soto-Castro D, et al. In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México. Bioorg Med Chem. 2021;48:116417doi: 10.1016/j.bmc.2021.116417.
Domínguez-Díaz, L. R., Eugenia Ochoa, M., Soto-Castro, D., Farfán, N., Morales-Chamorro, M., Yépez-Mulia, L., Pérez-Campos, E., Santillan, R., & Moreno-Rodríguez, A. (2021). In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México. Bioorganic & medicinal chemistry, 48116417. https://doi.org/10.1016/j.bmc.2021.116417
Domínguez-Díaz, Luis Roberto, et al. "In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México." Bioorganic & medicinal chemistry vol. 48 (2021): 116417. doi: https://doi.org/10.1016/j.bmc.2021.116417
Domínguez-Díaz LR, Eugenia Ochoa M, Soto-Castro D, Farfán N, Morales-Chamorro M, Yépez-Mulia L, Pérez-Campos E, Santillan R, Moreno-Rodríguez A. In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México. Bioorg Med Chem. 2021 Oct 15;48:116417. doi: 10.1016/j.bmc.2021.116417. Epub 2021 Sep 20. PMID: 34571489.
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Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes.

Evidence-based complementary and alternative medicine : eCAM

Jiménez-Arellanes A, León-Díaz R, Meckes M, Tapia A, Molina-Salinas GM, Luna-Herrera J, Yépez-Mulia L.
PMID: 22454670
Evid Based Complement Alternat Med. 2012;2012:593403. doi: 10.1155/2012/593403. Epub 2012 Feb 16.

We analyzed the antimycobacterial activity of the hexane extract of rhizomes from Aristolochia elegans. Some compounds of this extract were purified and tested against a group of drug-resistant Mycobacterium tuberculosis strains. We also evaluated their antiprotozoal activities. The hexane...

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Jiménez-Arellanes A, León-Díaz R, Meckes M, et al. Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. Evid Based Complement Alternat Med. 2012;2012:593403doi: 10.1155/2012/593403.
Jiménez-Arellanes, A., León-Díaz, R., Meckes, M., Tapia, A., Molina-Salinas, G. M., Luna-Herrera, J., & Yépez-Mulia, L. (2012). Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. Evidence-based complementary and alternative medicine : eCAM, 2012593403. https://doi.org/10.1155/2012/593403
Jiménez-Arellanes, Adelina, et al. "Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes." Evidence-based complementary and alternative medicine : eCAM vol. 2012 (2012): 593403. doi: https://doi.org/10.1155/2012/593403
Jiménez-Arellanes A, León-Díaz R, Meckes M, Tapia A, Molina-Salinas GM, Luna-Herrera J, Yépez-Mulia L. Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. Evid Based Complement Alternat Med. 2012;2012:593403. doi: 10.1155/2012/593403. Epub 2012 Feb 16. PMID: 22454670; PMCID: PMC3292206.
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Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes.

Evidence-based complementary and alternative medicine : eCAM

Jiménez-Arellanes A, León-Díaz R, Meckes M, Tapia A, Molina-Salinas GM, Luna-Herrera J, Yépez-Mulia L.
PMID: 22454670
Evid Based Complement Alternat Med. 2012;2012:593403. doi: 10.1155/2012/593403. Epub 2012 Feb 16.

We analyzed the antimycobacterial activity of the hexane extract of rhizomes from Aristolochia elegans. Some compounds of this extract were purified and tested against a group of drug-resistant Mycobacterium tuberculosis strains. We also evaluated their antiprotozoal activities. The hexane...

Cite
Jiménez-Arellanes A, León-Díaz R, Meckes M, et al. Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. Evid Based Complement Alternat Med. 2012;2012:593403doi: 10.1155/2012/593403.
Jiménez-Arellanes, A., León-Díaz, R., Meckes, M., Tapia, A., Molina-Salinas, G. M., Luna-Herrera, J., & Yépez-Mulia, L. (2012). Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. Evidence-based complementary and alternative medicine : eCAM, 2012593403. https://doi.org/10.1155/2012/593403
Jiménez-Arellanes, Adelina, et al. "Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes." Evidence-based complementary and alternative medicine : eCAM vol. 2012 (2012): 593403. doi: https://doi.org/10.1155/2012/593403
Jiménez-Arellanes A, León-Díaz R, Meckes M, Tapia A, Molina-Salinas GM, Luna-Herrera J, Yépez-Mulia L. Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. Evid Based Complement Alternat Med. 2012;2012:593403. doi: 10.1155/2012/593403. Epub 2012 Feb 16. PMID: 22454670; PMCID: PMC3292206.
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Antiprotozoal Constituents from .

Pharmacognosy magazine

Calzada F, Correa-Basurto J, Barbosa E, Mendez-Luna D, Yepez-Mulia L.
PMID: 28216899
Pharmacogn Mag. 2017 Jan-Mar;13(49):148-152. doi: 10.4103/0973-1296.197636.

OBJECTIVE: This work was undertaken to obtain information that support the traditional use of MATERIAL AND METHODS: Bioassay-guided fractionation of the ethanol extract of the leaves of RESULTS: The CONCLUSION: Considering that PFOR is a target of metronidazole; kaempferol...

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Calzada F, Correa-Basurto J, Barbosa E, et al. Antiprotozoal Constituents from . Pharmacogn Mag. 2017;13(49):148-152doi: 10.4103/0973-1296.197636.
Calzada, F., Correa-Basurto, J., Barbosa, E., Mendez-Luna, D., & Yepez-Mulia, L. (2017). Antiprotozoal Constituents from . Pharmacognosy magazine, 13(49), 148-152. https://doi.org/10.4103/0973-1296.197636
Calzada, Fernando, et al. "Antiprotozoal Constituents from ." Pharmacognosy magazine vol. 13,49 (2017): 148-152. doi: https://doi.org/10.4103/0973-1296.197636
Calzada F, Correa-Basurto J, Barbosa E, Mendez-Luna D, Yepez-Mulia L. Antiprotozoal Constituents from . Pharmacogn Mag. 2017 Jan-Mar;13(49):148-152. doi: 10.4103/0973-1296.197636. PMID: 28216899; PMCID: PMC5307900.
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Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from .

International journal of molecular sciences

Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, Castillo R, Yépez-Mulia L, Oria-Hernández J, Méndez ST, Sierra-Campos E, Valdez-Solana M, Martínez-Caballero S, Hermoso JA, Romo-Mancillas A, Téllez-Valencia A.
PMID: 34948408
Int J Mol Sci. 2021 Dec 19;22(24). doi: 10.3390/ijms222413613.

Leishmaniasis is a disease caused by parasites of the

Cite
Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, et al. Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from . Int J Mol Sci. 2021;22(24)doi: 10.3390/ijms222413613.
Betancourt-Conde, I., Avitia-Domínguez, C., Hernández-Campos, A., Castillo, R., Yépez-Mulia, L., Oria-Hernández, J., Méndez, S. T., Sierra-Campos, E., Valdez-Solana, M., Martínez-Caballero, S., Hermoso, J. A., Romo-Mancillas, A., & Téllez-Valencia, A. (2021). Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from . International journal of molecular sciences, 22(24), . https://doi.org/10.3390/ijms222413613
Betancourt-Conde, Irene, et al. "Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from ." International journal of molecular sciences vol. 22,24 (2021). doi: https://doi.org/10.3390/ijms222413613
Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, Castillo R, Yépez-Mulia L, Oria-Hernández J, Méndez ST, Sierra-Campos E, Valdez-Solana M, Martínez-Caballero S, Hermoso JA, Romo-Mancillas A, Téllez-Valencia A. Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from . Int J Mol Sci. 2021 Dec 19;22(24). doi: 10.3390/ijms222413613. PMID: 34948408.
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In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México.

Bioorganic & medicinal chemistry

Domínguez-Díaz LR, Eugenia Ochoa M, Soto-Castro D, Farfán N, Morales-Chamorro M, Yépez-Mulia L, Pérez-Campos E, Santillan R, Moreno-Rodríguez A.
PMID: 34571489
Bioorg Med Chem. 2021 Oct 15;48:116417. doi: 10.1016/j.bmc.2021.116417. Epub 2021 Sep 20.

Chagas disease is a health problem that affects millions of persons, currently Nifurtimox (Nfx) and Benznidazole (Bz) are the unique drugs to treat it. However, these drugs produce adverse effects and high toxicity, which has motivated the search for...

Cite
Domínguez-Díaz LR, Eugenia Ochoa M, Soto-Castro D, et al. In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México. Bioorg Med Chem. 2021;48:116417doi: 10.1016/j.bmc.2021.116417.
Domínguez-Díaz, L. R., Eugenia Ochoa, M., Soto-Castro, D., Farfán, N., Morales-Chamorro, M., Yépez-Mulia, L., Pérez-Campos, E., Santillan, R., & Moreno-Rodríguez, A. (2021). In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México. Bioorganic & medicinal chemistry, 48116417. https://doi.org/10.1016/j.bmc.2021.116417
Domínguez-Díaz, Luis Roberto, et al. "In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México." Bioorganic & medicinal chemistry vol. 48 (2021): 116417. doi: https://doi.org/10.1016/j.bmc.2021.116417
Domínguez-Díaz LR, Eugenia Ochoa M, Soto-Castro D, Farfán N, Morales-Chamorro M, Yépez-Mulia L, Pérez-Campos E, Santillan R, Moreno-Rodríguez A. In vitro, ex vivo and in vivo short-term screening of DHEA nitrate derivatives activity over Trypanosoma cruzi Ninoa and TH strains from Oaxaca State, México. Bioorg Med Chem. 2021 Oct 15;48:116417. doi: 10.1016/j.bmc.2021.116417. Epub 2021 Sep 20. PMID: 34571489.
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Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from .

International journal of molecular sciences

Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, Castillo R, Yépez-Mulia L, Oria-Hernández J, Méndez ST, Sierra-Campos E, Valdez-Solana M, Martínez-Caballero S, Hermoso JA, Romo-Mancillas A, Téllez-Valencia A.
PMID: 34948408
Int J Mol Sci. 2021 Dec 19;22(24). doi: 10.3390/ijms222413613.

Leishmaniasis is a disease caused by parasites of the

Cite
Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, et al. Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from . Int J Mol Sci. 2021;22(24)doi: 10.3390/ijms222413613.
Betancourt-Conde, I., Avitia-Domínguez, C., Hernández-Campos, A., Castillo, R., Yépez-Mulia, L., Oria-Hernández, J., Méndez, S. T., Sierra-Campos, E., Valdez-Solana, M., Martínez-Caballero, S., Hermoso, J. A., Romo-Mancillas, A., & Téllez-Valencia, A. (2021). Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from . International journal of molecular sciences, 22(24), . https://doi.org/10.3390/ijms222413613
Betancourt-Conde, Irene, et al. "Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from ." International journal of molecular sciences vol. 22,24 (2021). doi: https://doi.org/10.3390/ijms222413613
Betancourt-Conde I, Avitia-Domínguez C, Hernández-Campos A, Castillo R, Yépez-Mulia L, Oria-Hernández J, Méndez ST, Sierra-Campos E, Valdez-Solana M, Martínez-Caballero S, Hermoso JA, Romo-Mancillas A, Téllez-Valencia A. Benzimidazole Derivatives as New and Selective Inhibitors of Arginase from . Int J Mol Sci. 2021 Dec 19;22(24). doi: 10.3390/ijms222413613. PMID: 34948408; PMCID: PMC8705706.
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Showing 1 to 9 of 9 entries