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Showing 1 to 12 of 127 entries
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Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells.

Hepatology research : the official journal of the Japan Society of Hepatology

Goto F, Kakinuma S, Miyoshi M, Tsunoda T, Kaneko S, Sato A, Asano Y, Otani S, Azuma S, Nagata H, Kawai-Kitahata F, Murakawa M, Nitta S, Itsui Y, Nakagawa M, Asahina Y, Watanabe M.
PMID: 27670640
Hepatol Res. 2017 Aug;47(9):941-952. doi: 10.1111/hepr.12823. Epub 2016 Oct 31.

Fetal hepatic stem/progenitor cells, called hepatoblasts, play central roles in liver organogenesis; however, molecular mechanisms regulating proliferation and terminal differentiation of such cells have not been completely elucidated. Bone morphogenetic protein-4 (BMP-4) is essential for the development of stem...

Log-normal diameter distribution of Pd-based metallic glass droplet and wire.

Scientific reports

Yaginuma S, Nakajima C, Kaneko N, Yokoyama Y, Nakayama KS.
PMID: 26030090
Sci Rep. 2015 Jun 01;5:10711. doi: 10.1038/srep10711.

We have studied the formation of Pd42.5Cu30Ni7.5P20 metallic glass droplets and wires in the gas atomization process. We demonstrate that the sizes of droplets and wires can be distinguished by the Ohnesorge number (Oh), which is the proportion of...

Treatment of Internal Hemorrhoids by Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid.

Diagnostic and therapeutic endoscopy

Tomiki Y, Ono S, Aoki J, Takahashi R, Ishiyama S, Sugimoto K, Yaginuma Y, Kojima Y, Goto M, Okuzawa A, Sakamoto K.
PMID: 26246785
Diagn Ther Endosc. 2015;2015:517690. doi: 10.1155/2015/517690. Epub 2015 Jul 12.

Objective. A new sclerosing agent for hemorrhoids, aluminum potassium sulfate and tannic acid (ALTA), is attracting attention as a curative treatment for internal hemorrhoids without resection. The outcome and safety of ALTA sclerotherapy using an endoscope were investigated in...

Oxygen consumption in relation to sorbitol utilization at the termination of diapause in eggs of the silkworm, Bombyx mori.

Journal of insect physiology

Yaginuma T, Yamashita O.
PMID: 12770347
J Insect Physiol. 1999 Jul;45(7):621-627. doi: 10.1016/s0022-1910(98)00150-4.

Rates of oxygen consumption were followed throughout the entire period of diapause in eggs of Bombyx mori. In non-diapause eggs at 25 degrees C, O(2) uptake was divisible into three phases, corresponding to morphogenetic processes. In diapause eggs at...

Enhancement of mitochondrial gene expression in the liver of primary biliary cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Chen CH, Nagayama K, Enomoto N, Miyasaka Y, Kurosaki M, Sakamoto N, Maekawa S, Kakinuma S, Ikeda T, Izumi N, Sato C, Watanabe M.
PMID: 15652467
Hepatol Res. 2005 Jan;31(1):24-30. doi: 10.1016/j.hepres.2004.09.007. Epub 2005 Jan 06.

Primary biliary cirrhosis (PBC) is one of the most important autoimmune liver diseases but the etiology and pathogenesis remain unknown. In this study, we analyzed differential mRNA expression in the liver of a patient with PBC using suppression subtractive...

The excitation of one-dimensional plasmons in Si and Au-Si complex atom wires.

Nanotechnology

Liu C, Inaoka T, Yaginuma S, Nakayama T, Aono M, Nagao T.
PMID: 21828837
Nanotechnology. 2008 Sep 03;19(35):355204. doi: 10.1088/0957-4484/19/35/355204. Epub 2008 Jul 17.

An atom-scale quantum wire array at the Au adsorbed Si(111) surface is studied by electron energy loss spectroscopy. Clear one-dimensional metallicity is verified by the observation of low-energy plasmonic excitation which exhibits a strong anisotropic dispersion. Our theoretical analysis...

DCC gene alterations in histological types and clinical stages of epithelial ovarian cancer.

International journal of oncology

Yamashita T, Yaginuma Y, Yamashita K, Fujita M, Ishikawa M.
PMID: 21541514
Int J Oncol. 1996 Aug;9(2):291-6. doi: 10.3892/ijo.9.2.291.

We examined loss of heterozygosity (LOH) and mRNA expression of the DCC gene in 77 tissues and 6 cell lines of human ovarian cancer. LOH was seen in serous and endometrioid adenocarcinomas but was not in clear cell and...

Enhanced expression of C-myc gene and binding-protein to the 2.3-kb upstream region of the p1 promoter in human liver and colon cancers.

International journal of oncology

Saigo K, Yaginuma K, Hayashi H, Isono K, Takada S, Koike K.
PMID: 21559686
Int J Oncol. 1994 Nov;5(5):1099-104. doi: 10.3892/ijo.5.5.1099.

We investigated binding proteins in the upstream regulatory region of c-myc gene in human liver and colon cancers. Gel shift assay revealed a nuclear protein which bound to the HindIII/PstI fragment (nt.-2328 to nt.-2118) upstream of the pi promoter...

IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment.

American journal of cancer research

Natsuizaka M, Kinugasa H, Kagawa S, Whelan KA, Naganuma S, Subramanian H, Chang S, Nakagawa KJ, Rustgi NL, Kita Y, Natsugoe S, Basu D, Gimotty PA, Klein-Szanto AJ, Diehl JA, Nakagawa H.
PMID: 24482736
Am J Cancer Res. 2014 Jan 15;4(1):29-41. eCollection 2014.

Insulin-like growth factor binding protein 3 (IGFBP3), a hypoxia-inducible gene, regulates a variety of cellular processes including cell proliferation, senescence, apoptosis and epithelial-mesenchymal transition (EMT). IGFBP3 has been linked to the pathogenesis of cancers. Most previous studies focus upon...

Observation of 8B solar neutrinos in the Kamiokande-II detector.

Physical review letters

Beier EW, Feldscher LR, Frank ED, Frati W, Hirata KS, Kajita T, Kaneyuki K, Kifune T, Kihara K, Kim SB, Koshiba M, Mann AK, Miyano K, Miyata H, Mori M, Nagashima H, Nakahata M, Nakamura K, Newcomer FM, Ohara S, Oyama Y, Sato N, Suda T, Suzuki A, Suzuki Y, Takahashi K, Takei H, Takita M, Tanimori T, Totsuka Y, Van Berg R, Yaginuma Y, Yamada M, Zhang W.
PMID: 10040421
Phys Rev Lett. 1989 Jul 03;63(1):16-19. doi: 10.1103/PhysRevLett.63.16.

No abstract available.

Effects of aromaticity in cations and their functional groups on the temperature dependence of low-frequency spectrum.

The Journal of chemical physics

Kakinuma S, Ramati S, Wishart JF, Shirota H.
PMID: 30307243
J Chem Phys. 2018 May 21;148(19):193805. doi: 10.1063/1.5010066.

In this study, we investigate the temperature dependence of low-frequency spectra in the frequency range of 0.3-200 cm

Comparing the Efficacy of a Microperforated Titanium Membrane for Guided Bone Regeneration with an Existing Mesh Retainer in Dog Mandibles.

Materials (Basel, Switzerland)

Hasegawa H, Kaneko T, Endo M, Kanno C, Yamazaki M, Yaginuma S, Igarashi H, Honma H, Masui S, Suto M, Sakisaka Y, Ishihata H.
PMID: 34204390
Materials (Basel). 2021 Jun 17;14(12). doi: 10.3390/ma14123358.

Acute-type lateral ridge defects (25 mm × 6 mm × 5 mm) were bilaterally created in the mandibles of four dogs (two defects per animal). The defects were reconstructed with particulate autologous bone and covered with a microperforated titanium...

Showing 1 to 12 of 127 entries