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Showing 1 to 12 of 627 entries
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[History of the Department of Physiology, Juntendo Medical College].

Nihon seirigaku zasshi. Journal of the Physiological Society of Japan

Mashima H, Takeuchi N.
PMID: 4878059
Nihon Seirigaku Zasshi. 1968;30(1):61-8.

No abstract available.

Topical rebamipide improves lid wiper epitheliopathy.

Clinical ophthalmology (Auckland, N.Z.)

Itakura H, Kashima T, Itakura M, Akiyama H, Kishi S.
PMID: 24204116
Clin Ophthalmol. 2013;7:2137-41. doi: 10.2147/opth.s5451. Epub 2013 Oct 31.

Administration of topical rebamipide increases the mucin level of tear film and improves the ocular surface in short break-up time type of dry eye. Lid wiper epitheliopathy (LWE) is a disorder of the marginal conjunctiva of the upper eyelid...

Chiral Template-Directed Regio-, Diastereo-, and Enantioselective Photodimerization of an Anthracene Derivative Assisted by Complementary Amidinium-Carboxylate Salt Bridge Formation.

Journal of the American Chemical Society

Tanabe J, Taura D, Ousaka N, Yashima E.
PMID: 28485968
J Am Chem Soc. 2017 May 31;139(21):7388-7398. doi: 10.1021/jacs.7b03317. Epub 2017 May 18.

A series of optically active amidine dimers composed of m-terphenyl backbones joined by a variety of linkers, such as achiral and chiral p-phenylene and chiral amide linkers, were synthesized and used as templates for the regio- (head-to-tail (HT) or...

Rhodium-Catalyzed Atroposelective [2 + 2 + 2] Cycloaddition of Ortho-Substituted Phenyl Diynes with Nitriles: Effect of Ortho Substituents on Regio- and Enantioselectivity.

Organic letters

Kashima K, Teraoka K, Uekusa H, Shibata Y, Tanaka K.
PMID: 27074498
Org Lett. 2016 May 06;18(9):2170-3. doi: 10.1021/acs.orglett.6b00791. Epub 2016 Apr 13.

Axially chiral 3-(2-halophenyl)pyridines were successfully synthesized in high yields with excellent enantioselectivity by the cationic rhodium(I)/(S)-H8-BINAP complex-catalyzed atroposelective [2 + 2 + 2] cycloaddition of (o-halophenyl)diynes with nitriles. Interestingly, regio- and enantioselectivity highly depend on ortho substituents on the...

Mechanistic understanding of alkyne cyclotrimerization on mononuclear and dinuclear scaffolds: [4 + 2] cycloaddition of the third alkyne onto metallacyclopentadienes and dimetallacyclopentadienes.

Dalton transactions (Cambridge, England : 2003)

Yamamoto K, Nagae H, Tsurugi H, Mashima K.
PMID: 27730228
Dalton Trans. 2016 Nov 01;45(43):17072-17081. doi: 10.1039/c6dt03389j.

Cyclotrimerization of alkynes catalyzed by transition metal complexes is a straightforward synthetic method for constructing a benzene skeleton in organic synthesis. Not only mononuclear complexes, but also multinuclear complexes act as catalysts for alkyne cyclotrimerization, and their reaction mechanisms...

In situ observation of a hydrogel-glass interface during sliding friction.

Soft matter

Yamamoto T, Kurokawa T, Ahmed J, Kamita G, Yashima S, Furukawa Y, Ota Y, Furukawa H, Gong JP.
PMID: 24962139
Soft Matter. 2014 Aug 14;10(30):5589-96. doi: 10.1039/c4sm00338a.

Direct observation of hydrogel contact with a solid surface in water is indispensable for understanding the friction, lubrication, and adhesion of hydrogels under water. However, this is a difficult task since the refractive index of hydrogels is very close...

Ultrametric distribution of culture vectors in an extended Axelrod model of cultural dissemination.

Scientific reports

Stivala A, Robins G, Kashima Y, Kirley M.
PMID: 24785715
Sci Rep. 2014 May 02;4:4870. doi: 10.1038/srep04870.

The Axelrod model of cultural diffusion is an apparently simple model that is capable of complex behaviour. A recent work used a real-world dataset of opinions as initial conditions, demonstrating the effects of the ultrametric distribution of empirical opinion...

Hydrogenation of amides catalyzed by a combined catalytic system of a Ru complex with a zinc salt.

Chemical communications (Cambridge, England)

Kita Y, Higuchi T, Mashima K.
PMID: 25112156
Chem Commun (Camb). 2014 Oct 04;50(76):11211-3. doi: 10.1039/c4cc04481a.

Addition of catalytic amounts of zinc salts facilitated the hydrogenation of amides catalyzed by a ruthenium complex bearing 2-(diphenylphosphino)ethanamine (L1). The combined catalytic system of the ruthenium complex [RuCl2(L1)2] with a zinc salt such as Zn(OCOCF3)2 mediated hydrogenation of...

AID, p53 and MLH1 expression in early gastric neoplasms and the correlation with the background mucosa.

Oncology letters

Kawata S, Yashima K, Yamamoto S, Sasaki S, Takeda Y, Hayashi A, Matsumoto K, Kawaguchi K, Harada K, Murawaki Y.
PMID: 26622562
Oncol Lett. 2015 Aug;10(2):737-743. doi: 10.3892/ol.2015.3342. Epub 2015 Jun 09.

A number of tumor-associated genes have been associated with gastric cancer development. The present study evaluated differences in tumor-associated protein expression and phenotype among early gastric neoplasms, and correlated these data with those of the background mucosa. The expression...

Control of Conformation and Chirality of Nonplanar π-Conjugated Diporphyrins Using Substituents and Axial Ligands.

Chemistry, an Asian journal

Ito S, Hiroto S, Ousaka N, Yashima E, Shinokubo H.
PMID: 26865108
Chem Asian J. 2016 Mar 18;11(6):936-42. doi: 10.1002/asia.201600105. Epub 2016 Feb 19.

Nonplanar conformations of pyrazine-fused Zn(II) diporphyrins could be controlled by the choice of the meso-aryl substituents and an axial ligand on the central metals. Zn(II) diporphyrins bearing sterically demanding meso-aryl groups with ortho-substituents led to a twisted chiral D2...

Enantioseparation on Riboflavin Derivatives Chemically Bonded to Silica Gel as Chiral Stationary Phases for HPLC.

Chirality

Kumano D, Iwahana S, Iida H, Shen C, Crassous J, Yashima E.
PMID: 25919938
Chirality. 2015 Aug;27(8):507-17. doi: 10.1002/chir.22452. Epub 2015 Apr 28.

Acetylated and/or 3,5-dimethylphenylcarbamated riboflavins were prepared and the resulting riboflavin derivatives as well as natural riboflavin were regioselectively immobilized on silica gel through chemical bonding at the 5'-O- or 3-N-position of the riboflavin to develop novel chiral stationary phases...

Studies of the Electronic Effects of Zinc Cluster Catalysts and Their Application to the Transesterification of β-Keto Esters.

Chemistry, an Asian journal

Agura K, Hayashi Y, Wada M, Nakatake D, Mashima K, Ohshima T.
PMID: 26918549
Chem Asian J. 2016 May 20;11(10):1548-54. doi: 10.1002/asia.201600062. Epub 2016 Apr 14.

The electronic effects of tetranuclear zinc cluster catalysts on transesterification were investigated by changing the carboxylate ligands in the clusters. High catalyst activity crucially depended on the balance between Lewis acidity and Brønsted basicity of the catalyst; this was...

Showing 1 to 12 of 627 entries