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Showing 1 to 12 of 23 entries
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Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

Nature genetics

Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, Chatterjee N, Thorleifsson G, Sulem P, Liu G, Kaaks R, Henrion M, Kinnersley B, Vallée M, Le Calvez-Kelm F, Stevens VL, Gapstur SM, Chen WV, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Njølstad I, Chen C, Goodman G, Benhamou S, Vooder T, Välk K, Nelis M, Metspalu A, Lener M, Lubiński J, Johansson M, Vineis P, Agudo A, Clavel-Chapelon F, Bueno-de-Mesquita HB, Trichopoulos D, Khaw KT, Johansson M, Weiderpass E, Tjønneland A, Riboli E, Lathrop M, Scelo G, Albanes D, Caporaso NE, Ye Y, Gu J, Wu X, Spitz MR, Dienemann H, Rosenberger A, Su L, Matakidou A, Eisen T, Stefansson K, Risch A, Chanock SJ, Christiani DC, Hung RJ, Brennan P, Landi MT, Houlston RS, Amos CI.
PMID: 28358128
Nat Genet. 2017 Mar 30;49(4):651. doi: 10.1038/ng0417-651a.

No abstract available.

Combining two technologies for full genome sequencing of human.

Acta naturae

Skryabin KG, Prokhortchouk EB, Mazur AM, Boulygina ES, Tsygankova SV, Nedoluzhko AV, Rastorguev SM, Matveev VB, Chekanov NN, D A G, Teslyuk AB, Gruzdeva NM, Velikhov VE, Zaridze DG, Kovalchuk MV.
PMID: 22649622
Acta Naturae. 2009 Oct;1(3):102-7.

At present, the new technologies of DNA sequencing are rapidly developing allowing quick and efficient characterisation of organisms at the level of the genome structure. In this study, the whole genome sequencing of a human (Russian man) was performed...

Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study.

Frontiers in oncology

Heck JE, Moore LE, Lee YC, McKay JD, Hung RJ, Karami S, Gaborieau V, Szeszenia-Dabrowska N, Zaridze DG, Mukeriya A, Mates D, Foretova L, Janout V, Kollárová H, Bencko V, Rothman N, Brennan P, Chow WH, Boffetta P.
PMID: 22645715
Front Oncol. 2012 Feb 20;2:16. doi: 10.3389/fonc.2012.00016. eCollection 2012.

BACKGROUND: The countries of Central and Eastern Europe have among the highest worldwide rates of renal cell cancer (RCC). Few studies have examined whether genetic variation in xenobiotic metabolic pathway genes may modify risk for this cancer.METHODS: The Central...

Rare deleterious germline variants and risk of lung cancer.

NPJ precision oncology

Liu Y, Xia J, McKay J, Tsavachidis S, Xiao X, Spitz MR, Cheng C, Byun J, Hong W, Li Y, Zhu D, Song Z, Rosenberg SM, Scheurer ME, Kheradmand F, Pikielny CW, Lusk CM, Schwartz AG, Wistuba II, Cho MH, Silverman EK, Bailey-Wilson J, Pinney SM, Anderson M, Kupert E, Gaba C, Mandal D, You M, de Andrade M, Yang P, Liloglou T, Davies MPA, Lissowska J, Swiatkowska B, Zaridze D, Mukeria A, Janout V, Holcatova I, Mates D, Stojsic J, Scelo G, Brennan P, Liu G, Field JK, Hung RJ, Christiani DC, Amos CI.
PMID: 33594163
NPJ Precis Oncol. 2021 Feb 16;5(1):12. doi: 10.1038/s41698-021-00146-7.

Recent studies suggest that rare variants exhibit stronger effect sizes and might play a crucial role in the etiology of lung cancers (LC). Whole exome plus targeted sequencing of germline DNA was performed on 1045 LC cases and 885...

Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing data.

NAR genomics and bioinformatics

Delhomme TM, Avogbe PH, Gabriel AAG, Alcala N, Leblay N, Voegele C, Vallée M, Chopard P, Chabrier A, Abedi-Ardekani B, Gaborieau V, Holcatova I, Janout V, Foretová L, Milosavljevic S, Zaridze D, Mukeriya A, Brambilla E, Brennan P, Scelo G, Fernandez-Cuesta L, Byrnes G, Calvez-Kelm FL, McKay JD, Foll M.
PMID: 32363341
NAR Genom Bioinform. 2020 Jun;2(2):lqaa021. doi: 10.1093/nargab/lqaa021. Epub 2020 Apr 20.

The emergence of next-generation sequencing (NGS) has revolutionized the way of reaching a genome sequence, with the promise of potentially providing a comprehensive characterization of DNA variations. Nevertheless, detecting somatic mutations is still a difficult problem, in particular when...

Sequence Variants and the Risk of Head and Neck Cancer: Pooled Analysis in the INHANCE Consortium.

Frontiers in oncology

Chuang SC, Agudo A, Ahrens W, Anantharaman D, Benhamou S, Boccia S, Chen C, Conway DI, Fabianova E, Hayes RB, Healy CM, Holcatova I, Kjaerheim K, Lagiou P, Lazarus P, Macfarlane TV, Mahimkar MB, Mates D, Matsuo K, Merletti F, Metspalu A, Morgenstern H, Muscat J, Cadoni G, Olshan AF, Purdue M, Ramroth H, Rudnai P, Schwartz SM, Simonato L, Smith EM, Sturgis EM, Szeszenia-Dabrowska N, Talamini R, Thomson P, Wei Q, Zaridze D, Zhang ZF, Znaor A, Brennan P, Boffetta P, Hashibe M.
PMID: 22655231
Front Oncol. 2011 Jul 12;1:13. doi: 10.3389/fonc.2011.00013. eCollection 2011.

Previous molecular epidemiological studies on head and neck cancer have examined various single nucleotide polymorphisms (SNPs), but there are very few documented associations. In the International head and neck cancer epidemiology (INHANCE) consortium, we evaluated associations between SNPs in...

The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

Dabo B, Pelucchi C, Rota M, Jain H, Bertuccio P, Bonzi R, Palli D, Ferraroni M, Zhang ZF, Sanchez-Anguiano A, Thi-Hai Pham Y, Thi-Du Tran C, Gia Pham A, Yu GP, Nguyen TC, Muscat J, Tsugane S, Hidaka A, Hamada GS, Zaridze D, Maximovitch D, Kogevinas M, Fernàndez de Larrea N, Boccia S, Pastorino R, Kurtz RC, Lagiou A, Lagiou P, Vioque J, Camargo MC, Paula Curado M, Lunet N, Boffetta P, Negri E, La Vecchia C, Luu HN.
PMID: 34183534
Eur J Cancer Prev. 2021 Jun 25; doi: 10.1097/CEJ.0000000000000703. Epub 2021 Jun 25.

BACKGROUND: Prior epidemiologic studies on the association between diabetes and gastric cancer risk provided inconclusive findings, while traditional, aggregate data meta-analyses were characterized by high between-study heterogeneity.OBJECTIVE: To investigate the association between type 2 diabetes and gastric cancer using...

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Oncotarget

Li Y, Xiao X, Bossé Y, Gorlova O, Gorlov I, Han Y, Byun J, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, Muley T, Risch A, Rosenberger A, Han J, Siminovitch K, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Houlston R, Artigas MS, Grankvist K, Johansson M, Shepherd FA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Liu G, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Christiani DC, Caporaso N, Johansson M, McKay JD, Brennan P, Hung RJ, Amos CI.
PMID: 30956756
Oncotarget. 2019 Mar 05;10(19):1760-1774. doi: 10.18632/oncotarget.26678. eCollection 2019 Mar 05.

The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterations and tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the epistasis existing among oncogenesis-related genes in lung cancer...

The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

Dabo B, Pelucchi C, Rota M, Jain H, Bertuccio P, Bonzi R, Palli D, Ferraroni M, Zhang ZF, Sanchez-Anguiano A, Thi-Hai Pham Y, Thi-Du Tran C, Gia Pham A, Yu GP, Nguyen TC, Muscat J, Tsugane S, Hidaka A, Hamada GS, Zaridze D, Maximovitch D, Kogevinas M, Fernàndez de Larrea N, Boccia S, Pastorino R, Kurtz RC, Lagiou A, Lagiou P, Vioque J, Camargo MC, Paula Curado M, Lunet N, Boffetta P, Negri E, La Vecchia C, Luu HN.
PMID: 34183534
Eur J Cancer Prev. 2021 Jun 25; doi: 10.1097/CEJ.0000000000000703. Epub 2021 Jun 25.

BACKGROUND: Prior epidemiologic studies on the association between diabetes and gastric cancer risk provided inconclusive findings, while traditional, aggregate data meta-analyses were characterized by high between-study heterogeneity.OBJECTIVE: To investigate the association between type 2 diabetes and gastric cancer using...

Family History and Gastric Cancer Risk: A Pooled Investigation in the Stomach Cancer Pooling (STOP) Project Consortium.

Cancers

Vitelli-Storelli F, Rubín-García M, Pelucchi C, Benavente Y, Bonzi R, Rota M, Palli D, Ferraroni M, Lunet N, Morais S, Ye W, Plymoth A, Malekzadeh R, Tsugane S, Hidaka A, Aragonés N, Castaño-Vinyals G, Zaridze DG, Maximovich D, Vioque J, García-de-la-Hera M, Zhang ZF, Shigueaki Hamada G, Pakseresht M, Pourfarzi F, Mu L, Boccia S, Pastorino R, Yu GP, Lagiou A, Lagiou P, Negri E, La Vecchia C, Martín V.
PMID: 34359744
Cancers (Basel). 2021 Jul 30;13(15). doi: 10.3390/cancers13153844.

Although there is a clear relationship between family history (FH) and the risk of gastric cancer (GC), quantification is still needed in relation to different histological types and anatomical sites, and in strata of covariates. The objective was to...

The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

Dabo B, Pelucchi C, Rota M, Jain H, Bertuccio P, Bonzi R, Palli D, Ferraroni M, Zhang ZF, Sanchez-Anguiano A, Thi-Hai Pham Y, Thi-Du Tran C, Gia Pham A, Yu GP, Nguyen TC, Muscat J, Tsugane S, Hidaka A, Hamada GS, Zaridze D, Maximovitch D, Kogevinas M, Fernàndez de Larrea N, Boccia S, Pastorino R, Kurtz RC, Lagiou A, Lagiou P, Vioque J, Camargo MC, Paula Curado M, Lunet N, Boffetta P, Negri E, La Vecchia C, Luu HN.
PMID: 34183534
Eur J Cancer Prev. 2021 Jun 25; doi: 10.1097/CEJ.0000000000000703. Epub 2021 Jun 25.

BACKGROUND: Prior epidemiologic studies on the association between diabetes and gastric cancer risk provided inconclusive findings, while traditional, aggregate data meta-analyses were characterized by high between-study heterogeneity.OBJECTIVE: To investigate the association between type 2 diabetes and gastric cancer using...

The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

Dabo B, Pelucchi C, Rota M, Jain H, Bertuccio P, Bonzi R, Palli D, Ferraroni M, Zhang ZF, Sanchez-Anguiano A, Thi-Hai Pham Y, Thi-Du Tran C, Gia Pham A, Yu GP, Nguyen TC, Muscat J, Tsugane S, Hidaka A, Hamada GS, Zaridze D, Maximovitch D, Kogevinas M, Fernàndez de Larrea N, Boccia S, Pastorino R, Kurtz RC, Lagiou A, Lagiou P, Vioque J, Camargo MC, Paula Curado M, Lunet N, Boffetta P, Negri E, La Vecchia C, Luu HN.
PMID: 34183534
Eur J Cancer Prev. 2021 Jun 25; doi: 10.1097/CEJ.0000000000000703. Epub 2021 Jun 25.

BACKGROUND: Prior epidemiologic studies on the association between diabetes and gastric cancer risk provided inconclusive findings, while traditional, aggregate data meta-analyses were characterized by high between-study heterogeneity.OBJECTIVE: To investigate the association between type 2 diabetes and gastric cancer using...

Showing 1 to 12 of 23 entries