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Showing 1 to 12 of 47 entries
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The Effects of Early Institutionalization and Foster Care Intervention on Children's Social Behaviors at Age 8.

Social development (Oxford, England)

Almas AN, Degnan KA, Walker OL, Radulescu A, Nelson CA, Zeanah CH, Fox NA.
PMID: 26294847
Soc Dev. 2015 May;24(2):225-239. doi: 10.1111/sode.12089.

The present study compared the social behaviors of 8-year-old previously institutionalized Romanian children from the Bucharest Early Intervention Project (BEIP) in two groups: 1) children randomized to foster care homes (FCG), and 2) children randomized to care as usual...

Alternatives for abandoned children: insights from the Bucharest Early Intervention Project.

Current opinion in psychology

Zeanah CH, Humphreys KL, Fox NA, Nelson CA.
PMID: 28813259
Curr Opin Psychol. 2017 Jun;15:182-188. doi: 10.1016/j.copsyc.2017.02.024. Epub 2017 Mar 10.

The Bucharest Early Intervention Project is the first and only randomized controlled trial of foster care as an alternative to institutional care for orphaned and abandoned children. Across various domains of brain and behavioral development we demonstrated that children...

Autonomic reactivity to social rejection, peer difficulties, and the buffering effects of adolescent friendships following early psychosocial deprivation.

Emotion (Washington, D.C.)

Tang A, McLaughlin KA, Sheridan MA, Nelson CA, Zeanah CH, Fox NA.
PMID: 34766790
Emotion. 2021 Nov 11; doi: 10.1037/emo0001016. Epub 2021 Nov 11.

Autonomic nervous system reactivity has been posited to be a mechanism contributing to social and emotional problems among children exposed to early adversity. Leveraging data from the Bucharest Early Intervention Project, a longitudinal randomized controlled trial of foster care...

Caregiver regulation: A modifiable target promoting resilience to early adverse experiences.

Psychological trauma : theory, research, practice and policy

Humphreys KL, King LS, Guyon-Harris KL, Zeanah CH.
PMID: 34460282
Psychol Trauma. 2021 Aug 30; doi: 10.1037/tra0001111. Epub 2021 Aug 30.

BACKGROUND: Experiences of adversity in early life are associated with increased risk for negative outcomes; yet, the impact of early adversity on any given child is difficult to predict given the considerable heterogeneity in functioning found even among children...

Long-Term Effects of Institutional Care and Enhanced Attachment Relationships on Close Adolescent Friendships.

Child development

Tang A, Almas A, Zeytinoglu S, Zeanah CH, Nelson CA, Fox NA.
PMID: 33997968
Child Dev. 2021 Nov;92(6):2431-2446. doi: 10.1111/cdev.13592. Epub 2021 May 16.

This study examined whether early institutional rearing and attachment security influence the quality and quantity of friendships at age 16 in 138 participants, including children abandoned to institutions in Bucharest, Romania, who were randomized to care as usual (n...

Association between fluoroquinolone utilization rates and susceptibilities of gram-negative bacilli: Results from an 8-year intervention by an antibiotic stewardship program in an inner-city United States hospital.

Science progress

Zeana C, Palmieri FE, Gupta V, Ye G, Lao P, Yu K, Kang KS, Schiller L, Purswani M.
PMID: 33908291
Sci Prog. 2021 Apr-Jun;104(2):368504211011876. doi: 10.1177/00368504211011876.

This study evaluated an antibiotic stewardship program (ASP) intervention aimed at reducing inpatient fluoroquinolone (FQ) use and examined its impact on ciprofloxacin susceptibilities of gram-negative bacteria in a large 611-bed community hospital. A two-step ASP intervention was implemented: an...

Annual research review: Attachment disorders in early childhood--clinical presentation, causes, correlates, and treatment.

Journal of child psychology and psychiatry, and allied disciplines

Zeanah CH, Gleason MM.
PMID: 25359236
J Child Psychol Psychiatry. 2015 Mar;56(3):207-22. doi: 10.1111/jcpp.12347. Epub 2014 Oct 31.

BACKGROUND: Though noted in the clinical literature for more than 50 years, attachment disorders have been studied systematically only recently. In part because of the ubiquity of attachments in humans, determining when aberrant behavior is best explained as an...

Commentary: Increasing diagnostic precision in reactive attachment disorder - a commentary on Allen & Schuengel (2019).

Child and adolescent mental health

Zeanah CH, Guyon-Harris KL.
PMID: 32285637
Child Adolesc Ment Health. 2020 Feb;25(1):11-12. doi: 10.1111/camh.12357. Epub 2019 Dec 01.

A study by Allen and Schuengel in this issue of the journal replicates and extends previous findings by Woolgar and Baldock (2015) indicating that community practitioners are far more likely to diagnose reactive attachment disorder in symptomatic children than...

An Unusual Case of Ototoxicity with Use of Oral Vancomycin.

Case reports in infectious diseases

Gomceli U, Vangala S, Zeana C, Kelly PJ, Singh M.
PMID: 30057833
Case Rep Infect Dis. 2018 Jul 03;2018:2980913. doi: 10.1155/2018/2980913. eCollection 2018.

INTRODUCTION: Systemic absorption of oral vancomycin is poor due to the size of the molecule and its pharmacokinetics. It has an elimination half life of 5-11 hours in patients with normal renal function. We present a rare case of...

Neural and Cognitive Factors Influencing the Emergence of Psychopathology: Insights From the Bucharest Early Intervention Project.

Child development perspectives

Troller-Renfree S, Zeanah CH, Nelson CA, Fox NA.
PMID: 29531577
Child Dev Perspect. 2018 Mar;12(1):28-33. doi: 10.1111/cdep.12251. Epub 2017 Sep 07.

The adverse effects of institutionalized care and psychosocial deprivation have been documented for more than 100 years. Children who have been raised in institutions are at heightened risk of developing internalizing and externalizing disorders. Given the profound biological and...

Psychosocial deprivation, executive functions, and the emergence of socio-emotional behavior problems.

Frontiers in human neuroscience

McDermott JM, Troller-Renfree S, Vanderwert R, Nelson CA, Zeanah CH, Fox NA.
PMID: 23675333
Front Hum Neurosci. 2013 May 10;7:167. doi: 10.3389/fnhum.2013.00167. eCollection 2013.

Early psychosocial deprivation can negatively impact the development of executive functions (EFs). Here we explore the impact of early psychosocial deprivation on behavioral and physiological measures (i.e., event-related potentials; ERPs) of two facets of EF, inhibitory control and response...

Infants and Toddlers in Foster Care.

Child development perspectives

Dozier M, Zeanah CH, Bernard K.
PMID: 24073015
Child Dev Perspect. 2013 Sep 01;7(3):166-171. doi: 10.1111/cdep.12033.

Young children involved in the child welfare system are susceptible to behavioral and physiological dysregulation. These children need nurturing care to develop organized attachments to caregivers; they need synchronous care to support their physiological and behavioral regulation; and they...

Showing 1 to 12 of 47 entries