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Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes.

Angewandte Chemie (International ed. in English)

Sandmeier T, Krautwald S, Zipfel HF, Carreira EM.
PMID: 26427612
Angew Chem Int Ed Engl. 2015 Nov 23;54(48):14363-7. doi: 10.1002/anie.201506933. Epub 2015 Oct 02.

Fully stereodivergent dual-catalytic α-allylation of protected α-amino- and α-hydroxyacetaldehydes is achieved through iridium- and amine-catalyzed substitution of racemic allylic alcohols with chiral enamines generated in situ. The operationally simple method furnishes useful aldehyde building blocks in good yields, more...

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Sandmeier T, Krautwald S, Zipfel HF, et al. Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes. Angew Chem Int Ed Engl. 2015;54(48):14363-7doi: 10.1002/anie.201506933.
Sandmeier, T., Krautwald, S., Zipfel, H. F., & Carreira, E. M. (2015). Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes. Angewandte Chemie (International ed. in English), 54(48), 14363-7. https://doi.org/10.1002/anie.201506933
Sandmeier, Tobias, et al. "Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes." Angewandte Chemie (International ed. in English) vol. 54,48 (2015): 14363-7. doi: https://doi.org/10.1002/anie.201506933
Sandmeier T, Krautwald S, Zipfel HF, Carreira EM. Stereodivergent Dual Catalytic α-Allylation of Protected α-Amino- and α-Hydroxyacetaldehydes. Angew Chem Int Ed Engl. 2015 Nov 23;54(48):14363-7. doi: 10.1002/anie.201506933. Epub 2015 Oct 02. PMID: 26427612.
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Within-Subject Associations between Mood Dimensions and Non-exercise Activity: An Ambulatory Assessment Approach Using Repeated Real-Time and Objective Data.

Frontiers in psychology

Reichert M, Tost H, Reinhard I, Zipf A, Salize HJ, Meyer-Lindenberg A, Ebner-Priemer UW.
PMID: 27445891
Front Psychol. 2016 Jun 24;7:918. doi: 10.3389/fpsyg.2016.00918. eCollection 2016.

A physically active lifestyle has been related to positive health outcomes and high life expectancy, but the underlying psychological mechanisms maintaining physical activity are rarely investigated. Tremendous technological progress yielding sophisticated methodological approaches, i.e., ambulatory assessment, have recently enabled...

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Reichert M, Tost H, Reinhard I, et al. Within-Subject Associations between Mood Dimensions and Non-exercise Activity: An Ambulatory Assessment Approach Using Repeated Real-Time and Objective Data. Front Psychol. 2016;7:918doi: 10.3389/fpsyg.2016.00918.
Reichert, M., Tost, H., Reinhard, I., Zipf, A., Salize, H. J., Meyer-Lindenberg, A., & Ebner-Priemer, U. W. (2016). Within-Subject Associations between Mood Dimensions and Non-exercise Activity: An Ambulatory Assessment Approach Using Repeated Real-Time and Objective Data. Frontiers in psychology, 7918. https://doi.org/10.3389/fpsyg.2016.00918
Reichert, Markus, et al. "Within-Subject Associations between Mood Dimensions and Non-exercise Activity: An Ambulatory Assessment Approach Using Repeated Real-Time and Objective Data." Frontiers in psychology vol. 7 (2016): 918. doi: https://doi.org/10.3389/fpsyg.2016.00918
Reichert M, Tost H, Reinhard I, Zipf A, Salize HJ, Meyer-Lindenberg A, Ebner-Priemer UW. Within-Subject Associations between Mood Dimensions and Non-exercise Activity: An Ambulatory Assessment Approach Using Repeated Real-Time and Objective Data. Front Psychol. 2016 Jun 24;7:918. doi: 10.3389/fpsyg.2016.00918. eCollection 2016. PMID: 27445891; PMCID: PMC4919351.
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The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in Para-Substituted Benzyl-Type Radicals.

The Journal of organic chemistry

Adam W, Kita F, Harrer HM, Nau WM, Zipf R.
PMID: 11667607
J Org Chem. 1996 Oct 04;61(20):7056-7065. doi: 10.1021/jo960396q.

The zero-field splitting parameters D of the symmetrically disubstituted and unsymmetrically monosubstituted 1,3-diaryl-1,3-cyclopentanediyl triplet diradicals 1, 2 (X = p-MeO, p-Me, p-Cl, p-NH(2), p-CO(2)Me, p-CN, p-NO(2)), and 5 were determined in 2-methyltetrahydrofuran glass at 77 K. The linear plot...

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Adam W, Kita F, Harrer HM, et al. The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in Para-Substituted Benzyl-Type Radicals. J Org Chem. 1996;61(20):7056-7065doi: 10.1021/jo960396q.
Adam, W., Kita, F., Harrer, H. M., Nau, W. M., & Zipf, R. (1996). The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in Para-Substituted Benzyl-Type Radicals. The Journal of organic chemistry, 61(20), 7056-7065. https://doi.org/10.1021/jo960396q
Adam, Waldemar, et al. "The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in Para-Substituted Benzyl-Type Radicals." The Journal of organic chemistry vol. 61,20 (1996): 7056-7065. doi: https://doi.org/10.1021/jo960396q
Adam W, Kita F, Harrer HM, Nau WM, Zipf R. The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in Para-Substituted Benzyl-Type Radicals. J Org Chem. 1996 Oct 04;61(20):7056-7065. doi: 10.1021/jo960396q. PMID: 11667607.
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Mosaicism in Prader-Willi syndrome.

American journal of medical genetics

Mowery-Rushton PA, Hanchett JM, Zipf WB, Rogan PK, Surti U.
PMID: 10722401
Am J Med Genet. 2000 Jan 17;90(2):177.

No abstract available.

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Mowery-Rushton PA, Hanchett JM, Zipf WB, et al. Mosaicism in Prader-Willi syndrome. Am J Med Genet. 2000;90(2):177
Mowery-Rushton, P. A., Hanchett, J. M., Zipf, W. B., Rogan, P. K., & Surti, U. (2000). Mosaicism in Prader-Willi syndrome. American journal of medical genetics, 90(2), 177.
Mowery-Rushton, P A, et al. "Mosaicism in Prader-Willi syndrome." American journal of medical genetics vol. 90,2 (2000): 177.
Mowery-Rushton PA, Hanchett JM, Zipf WB, Rogan PK, Surti U. Mosaicism in Prader-Willi syndrome. Am J Med Genet. 2000 Jan 17;90(2):177. PMID: 10722401.
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[Late development & prognosis of myocardial infarct; observations on 788 patients].

Deutsche medizinische Wochenschrift (1946)

ZIPP H, PROLL G.
PMID: 13547826
Dtsch Med Wochenschr. 1958 Jun 06;83(23):1014-20. doi: 10.1055/s-0028-1114394.

No abstract available.

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ZIPP H, PROLL G. Der spätere Verlauf und die Prognose des Herzinfarktes; Beobachtungen an 788 Kranken. [Late development & prognosis of myocardial infarct; observations on 788 patients]. Dtsch Med Wochenschr. 1958;83(23):1014-20doi: 10.1055/s-0028-1114394.
ZIPP, H., & PROLL, G. (1958). Der spätere Verlauf und die Prognose des Herzinfarktes; Beobachtungen an 788 Kranken. [Late development & prognosis of myocardial infarct; observations on 788 patients]. Deutsche medizinische Wochenschrift (1946), 83(23), 1014-20. https://doi.org/10.1055/s-0028-1114394
ZIPP, H, and PROLL, G. "Der spätere Verlauf und die Prognose des Herzinfarktes; Beobachtungen an 788 Kranken." [Late development & prognosis of myocardial infarct; observations on 788 patients]. Deutsche medizinische Wochenschrift (1946) vol. 83,23 (1958): 1014-20. doi: https://doi.org/10.1055/s-0028-1114394
ZIPP H, PROLL G. Der spätere Verlauf und die Prognose des Herzinfarktes; Beobachtungen an 788 Kranken. [Late development & prognosis of myocardial infarct; observations on 788 patients]. Dtsch Med Wochenschr. 1958 Jun 06;83(23):1014-20. doi: 10.1055/s-0028-1114394. Undetermined. PMID: 13547826.
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Synthesis, structures and reactivity of ruthenium nitrosyl complexes containing Kläui's oxygen tripodal ligand.

Dalton transactions (Cambridge, England : 2003)

Ip HF, Yi XY, Wong WY, Williams ID, Leung WH.
PMID: 21927766
Dalton Trans. 2011 Nov 07;40(41):11043-50. doi: 10.1039/c1dt10306g. Epub 2011 Sep 19.

Ruthenium nitrosyl complexes containing the Kläui's oxgyen tripodal ligand L(OEt)(-) ([CpCo{P(O)(OEt)(2)}(3)](-) where Cp = η(5)-C(5)H(5)) were synthesized and their photolysis studied. The treatment of [Ru(N^N)(NO)Cl(3)] with [AgL(OEt)] and Ag(OTf) afforded [L(OEt)Ru(N^N)(NO)][OTf](2) where N^N = 4,4'-di-tert-butyl-2,2'-bipyridyl (dtbpy) (2·[OTf](2)), 2,2'-bipyridyl (bpy)...

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Ip HF, Yi XY, Wong WY, et al. Synthesis, structures and reactivity of ruthenium nitrosyl complexes containing Kläui's oxygen tripodal ligand. Dalton Trans. 2011;40(41):11043-50doi: 10.1039/c1dt10306g.
Ip, H. F., Yi, X. Y., Wong, W. Y., Williams, I. D., & Leung, W. H. (2011). Synthesis, structures and reactivity of ruthenium nitrosyl complexes containing Kläui's oxygen tripodal ligand. Dalton transactions (Cambridge, England : 2003), 40(41), 11043-50. https://doi.org/10.1039/c1dt10306g
Ip, Ho-Fai, et al. "Synthesis, structures and reactivity of ruthenium nitrosyl complexes containing Kläui's oxygen tripodal ligand." Dalton transactions (Cambridge, England : 2003) vol. 40,41 (2011): 11043-50. doi: https://doi.org/10.1039/c1dt10306g
Ip HF, Yi XY, Wong WY, Williams ID, Leung WH. Synthesis, structures and reactivity of ruthenium nitrosyl complexes containing Kläui's oxygen tripodal ligand. Dalton Trans. 2011 Nov 07;40(41):11043-50. doi: 10.1039/c1dt10306g. Epub 2011 Sep 19. PMID: 21927766.
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Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis.

Therapeutic advances in neurological disorders

Fleischer V, Koirala N, Droby A, Gracien RM, Deichmann R, Ziemann U, Meuth SG, Muthuraman M, Zipp F, Groppa S.
PMID: 31040880
Ther Adv Neurol Disord. 2019 Apr 24;12:1756286419838673. doi: 10.1177/1756286419838673. eCollection 2019.

BACKGROUND: Network science provides powerful access to essential organizational principles of the brain. The aim of this study was to investigate longitudinal evolution of gray matter networks in early relapsing-remitting MS (RRMS) compared with healthy controls (HCs) and contrast...

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Fleischer V, Koirala N, Droby A, et al. Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis. Ther Adv Neurol Disord. 2019;12:1756286419838673doi: 10.1177/1756286419838673.
Fleischer, V., Koirala, N., Droby, A., Gracien, R. M., Deichmann, R., Ziemann, U., Meuth, S. G., Muthuraman, M., Zipp, F., & Groppa, S. (2019). Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis. Therapeutic advances in neurological disorders, 121756286419838673. https://doi.org/10.1177/1756286419838673
Fleischer, Vinzenz, et al. "Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis." Therapeutic advances in neurological disorders vol. 12 (2019): 1756286419838673. doi: https://doi.org/10.1177/1756286419838673
Fleischer V, Koirala N, Droby A, Gracien RM, Deichmann R, Ziemann U, Meuth SG, Muthuraman M, Zipp F, Groppa S. Longitudinal cortical network reorganization in early relapsing-remitting multiple sclerosis. Ther Adv Neurol Disord. 2019 Apr 24;12:1756286419838673. doi: 10.1177/1756286419838673. eCollection 2019. PMID: 31040880; PMCID: PMC6482642.
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Multiple sclerosis therapy consensus group (MSTCG): answers to the discussion questions.

Neurological research and practice

Wiendl H, Gold R, Zipp F.
PMID: 34362473
Neurol Res Pract. 2021 Aug 06;3(1):44. doi: 10.1186/s42466-021-00140-1.

No abstract available.

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Wiendl H, Gold R, Zipp F. Multiple sclerosis therapy consensus group (MSTCG): answers to the discussion questions. Neurol Res Pract. 2021;3(1):44doi: 10.1186/s42466-021-00140-1.
Wiendl, H., Gold, R., Zipp, F. (2021). Multiple sclerosis therapy consensus group (MSTCG): answers to the discussion questions. Neurological research and practice, 3(1), 44. https://doi.org/10.1186/s42466-021-00140-1
Wiendl, Heinz, et al. "Multiple sclerosis therapy consensus group (MSTCG): answers to the discussion questions." Neurological research and practice vol. 3,1 (2021): 44. doi: https://doi.org/10.1186/s42466-021-00140-1
Wiendl H, Gold R, Zipp F. Multiple sclerosis therapy consensus group (MSTCG): answers to the discussion questions. Neurol Res Pract. 2021 Aug 06;3(1):44. doi: 10.1186/s42466-021-00140-1. PMID: 34362473; PMCID: PMC8344158.
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Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.

Brain : a journal of neurology

Liebmann M, Korn L, Janoschka C, Albrecht S, Lauks S, Herrmann AM, Schulte-Mecklenbeck A, Schwab N, Schneider-Hohendorf T, Eveslage M, Wildemann B, Luessi F, Schmidt S, Diebold M, Bittner S, Gross CC, Kovac S, Zipp F, Derfuss T, Kuhlmann T, König S, Meuth SG, Wiendl H, Klotz L.
PMID: 34849598
Brain. 2021 Nov 29;144(10):3126-3141. doi: 10.1093/brain/awab307.

Dimethyl fumarate, an approved treatment for relapsing-remitting multiple sclerosis, exerts pleiotropic effects on immune cells as well as CNS resident cells. Here, we show that dimethyl fumarate exerts a profound alteration of the metabolic profile of human CD4+ as...

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Liebmann M, Korn L, Janoschka C, et al. Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity. Brain. 2021;144(10):3126-3141doi: 10.1093/brain/awab307.
Liebmann, M., Korn, L., Janoschka, C., Albrecht, S., Lauks, S., Herrmann, A. M., Schulte-Mecklenbeck, A., Schwab, N., Schneider-Hohendorf, T., Eveslage, M., Wildemann, B., Luessi, F., Schmidt, S., Diebold, M., Bittner, S., Gross, C. C., Kovac, S., Zipp, F., Derfuss, T., Kuhlmann, T., König, S., Meuth, S. G., Wiendl, H., & Klotz, L. (2021). Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity. Brain : a journal of neurology, 144(10), 3126-3141. https://doi.org/10.1093/brain/awab307
Liebmann, Marie, et al. "Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity." Brain : a journal of neurology vol. 144,10 (2021): 3126-3141. doi: https://doi.org/10.1093/brain/awab307
Liebmann M, Korn L, Janoschka C, Albrecht S, Lauks S, Herrmann AM, Schulte-Mecklenbeck A, Schwab N, Schneider-Hohendorf T, Eveslage M, Wildemann B, Luessi F, Schmidt S, Diebold M, Bittner S, Gross CC, Kovac S, Zipp F, Derfuss T, Kuhlmann T, König S, Meuth SG, Wiendl H, Klotz L. Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity. Brain. 2021 Nov 29;144(10):3126-3141. doi: 10.1093/brain/awab307. PMID: 34849598; PMCID: PMC8634070.
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Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis.

Therapeutic advances in neurological disorders

Seitz CB, Steffen F, Muthuraman M, Uphaus T, Krämer J, Meuth SG, Albrecht P, Groppa S, Zipp F, Bittner S, Fleischer V.
PMID: 34104217
Ther Adv Neurol Disord. 2021 May 25;14:17562864211003478. doi: 10.1177/17562864211003478. eCollection 2021.

BACKGROUND: Serum neurofilament light chain (sNfL) and distinct intra-retinal layers are both promising biomarkers of neuro-axonal injury in multiple sclerosis (MS). We aimed to unravel the association of both markers in early MS, having identified that neurofilament has a...

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Seitz CB, Steffen F, Muthuraman M, et al. Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis. Ther Adv Neurol Disord. 2021;14:17562864211003478doi: 10.1177/17562864211003478.
Seitz, C. B., Steffen, F., Muthuraman, M., Uphaus, T., Krämer, J., Meuth, S. G., Albrecht, P., Groppa, S., Zipp, F., Bittner, S., & Fleischer, V. (2021). Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis. Therapeutic advances in neurological disorders, 1417562864211003478. https://doi.org/10.1177/17562864211003478
Seitz, Caspar B, et al. "Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis." Therapeutic advances in neurological disorders vol. 14 (2021): 17562864211003478. doi: https://doi.org/10.1177/17562864211003478
Seitz CB, Steffen F, Muthuraman M, Uphaus T, Krämer J, Meuth SG, Albrecht P, Groppa S, Zipp F, Bittner S, Fleischer V. Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis. Ther Adv Neurol Disord. 2021 May 25;14:17562864211003478. doi: 10.1177/17562864211003478. eCollection 2021. PMID: 34104217; PMCID: PMC8155762.
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Subcortical volumes as early predictors of fatigue in multiple sclerosis.

Annals of neurology

Fleischer V, Ciolac D, Gonzalez-Escamilla G, Grothe M, Strauss S, Molina Galindo LS, Radetz A, Salmen A, Lukas C, Klotz L, Meuth SG, Bayas A, Paul F, Hartung HP, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Kümpfel T, Zettl UK, Knop M, Tumani H, Wiendl H, Gold R, Bittner S, Zipp F, Groppa S, Muthuraman M.
PMID: 34967456
Ann Neurol. 2021 Dec 30; doi: 10.1002/ana.26290. Epub 2021 Dec 30.

OBJECTIVE: Fatigue is a frequent and severe symptom in multiple sclerosis (MS), but its pathophysiological origin remains incompletely understood. We aimed to examine the predictive value of subcortical gray matter volumes for fatigue severity at disease onset and after...

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Fleischer V, Ciolac D, Gonzalez-Escamilla G, et al. Subcortical volumes as early predictors of fatigue in multiple sclerosis. Ann Neurol. 2021;doi: 10.1002/ana.26290.
Fleischer, V., Ciolac, D., Gonzalez-Escamilla, G., Grothe, M., Strauss, S., Molina Galindo, L. S., Radetz, A., Salmen, A., Lukas, C., Klotz, L., Meuth, S. G., Bayas, A., Paul, F., Hartung, H. P., Heesen, C., Stangel, M., Wildemann, B., Bergh, F. T., Tackenberg, B., Kümpfel, T., Zettl, U. K., Knop, M., Tumani, H., Wiendl, H., Gold, R., Bittner, S., Zipp, F., Groppa, S., Muthuraman, M. (2021). Subcortical volumes as early predictors of fatigue in multiple sclerosis. Annals of neurology, . https://doi.org/10.1002/ana.26290
Fleischer, Vinzenz, et al. "Subcortical volumes as early predictors of fatigue in multiple sclerosis." Annals of neurology vol. (2021). doi: https://doi.org/10.1002/ana.26290
Fleischer V, Ciolac D, Gonzalez-Escamilla G, Grothe M, Strauss S, Molina Galindo LS, Radetz A, Salmen A, Lukas C, Klotz L, Meuth SG, Bayas A, Paul F, Hartung HP, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Kümpfel T, Zettl UK, Knop M, Tumani H, Wiendl H, Gold R, Bittner S, Zipp F, Groppa S, Muthuraman M. Subcortical volumes as early predictors of fatigue in multiple sclerosis. Ann Neurol. 2021 Dec 30; doi: 10.1002/ana.26290. Epub 2021 Dec 30. PMID: 34967456.
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Reprogramming sphingolipid glycosylation is required for endosymbiont persistence in Medicago truncatula.

Current biology : CB

Moore WM, Chan C, Ishikawa T, Rennie EA, Wipf HM, Benites V, Kawai-Yamada M, Mortimer JC, Scheller HV.
PMID: 33857428
Curr Biol. 2021 Jun 07;31(11):2374-2385.e4. doi: 10.1016/j.cub.2021.03.067. Epub 2021 Apr 14.

Plant endosymbiosis relies on the development of specialized membranes that encapsulate the endosymbiont and facilitate nutrient exchange. However, the identity and function of lipids within these membrane interfaces is largely unknown. Here, we identify GLUCOSAMINE INOSITOL PHOSPHORYLCERAMIDE TRANSFERASE1 (GINT1)...

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Moore WM, Chan C, Ishikawa T, et al. Reprogramming sphingolipid glycosylation is required for endosymbiont persistence in Medicago truncatula. Curr Biol. 2021;31(11):2374-2385.e4doi: 10.1016/j.cub.2021.03.067.
Moore, W. M., Chan, C., Ishikawa, T., Rennie, E. A., Wipf, H. M., Benites, V., Kawai-Yamada, M., Mortimer, J. C., & Scheller, H. V. (2021). Reprogramming sphingolipid glycosylation is required for endosymbiont persistence in Medicago truncatula. Current biology : CB, 31(11), 2374-2385.e4. https://doi.org/10.1016/j.cub.2021.03.067
Moore, William M, et al. "Reprogramming sphingolipid glycosylation is required for endosymbiont persistence in Medicago truncatula." Current biology : CB vol. 31,11 (2021): 2374-2385.e4. doi: https://doi.org/10.1016/j.cub.2021.03.067
Moore WM, Chan C, Ishikawa T, Rennie EA, Wipf HM, Benites V, Kawai-Yamada M, Mortimer JC, Scheller HV. Reprogramming sphingolipid glycosylation is required for endosymbiont persistence in Medicago truncatula. Curr Biol. 2021 Jun 07;31(11):2374-2385.e4. doi: 10.1016/j.cub.2021.03.067. Epub 2021 Apr 14. PMID: 33857428.
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