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Showing 1 to 9 of 9 entries
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Author Correction: Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.

Nature genetics

Orrù V, Steri M, Sidore C, Marongiu M, Serra V, Olla S, Sole G, Lai S, Dei M, Mulas A, Virdis F, Piras MG, Lobina M, Marongiu M, Pitzalis M, Deidda F, Loizedda A, Onano S, Zoledziewska M, Sawcer S, Devoto M, Gorospe M, Abecasis GR, Floris M, Pala M, Schlessinger D, Fiorillo E, Cucca F.
PMID: 32948852
Nat Genet. 2020 Nov;52(11):1266. doi: 10.1038/s41588-020-00718-6.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Effect of Different Disease-Modifying Therapies on Humoral Response to BNT162b2 Vaccine in Sardinian Multiple Sclerosis Patients.

Frontiers in immunology

Pitzalis M, Idda ML, Lodde V, Loizedda A, Lobina M, Zoledziewska M, Virdis F, Delogu G, Pirinu F, Marini MG, Mingoia M, Frau J, Lorefice L, Fronza M, Carmagnini D, Carta E, Orrù V, Uzzau S, Solla P, Loi F, Devoto M, Steri M, Fiorillo E, Floris M, Zarbo IR, Cocco E, Cucca F.
PMID: 34956211
Front Immunol. 2021 Dec 09;12:781843. doi: 10.3389/fimmu.2021.781843. eCollection 2021.

OBJECTIVES: Vaccination against COVID-19 is highly recommended to patients affected by multiple sclerosis (MS); however, the impact of MS disease-modifying therapies (DMTs) on the immune response following vaccination has been only partially investigated. Here, we aimed to elucidate the...

The dependence of serum interleukin-6 level on PPAR-alpha polymorphism in men with coronary atherosclerosis.

European journal of internal medicine

Skoczynska A, Dobosz T, Poreba R, Turczyn B, Derkacz A, Zoledziewska M, Jonkisz A, Lebioda A.
PMID: 16275545
Eur J Intern Med. 2005 Nov;16(7):501-6. doi: 10.1016/j.ejim.2005.04.012.

BACKGROUND: The association between L162V polymorphism in the gene for peroxisome proliferator activated receptor (PPAR) alpha and the development of coronary heart disease was examined.METHODS: PPAR-alpha polymorphism was determined in 48 men with angiographically confirmed coronary atherosclerosis and in...

Genetic variant within CDK6 regulates immune response to palbociclib treatment.

Clinical immunology (Orlando, Fla.)

Serra V, Orrù V, Steri M, Fiorillo E, Cucca F, Zoledziewska M.
PMID: 34116212
Clin Immunol. 2021 Jun 08;108777. doi: 10.1016/j.clim.2021.108777. Epub 2021 Jun 08.

Everyone carries a set of genetic variants that contribute to regulation of the levels of blood cells, with unknown clinical impact. One of them, rs445 within the cell-cycle checkpoint gene CDK6, reduces the levels of myeloid cell types including...

Genome-Wide Analysis Studies and Chronic Kidney Disease.

Kidney diseases (Basel, Switzerland)

Piras D, Zoledziewska M, Cucca F, Pani A.
PMID: 29344505
Kidney Dis (Basel). 2017 Dec;3(3):106-110. doi: 10.1159/000481886. Epub 2017 Nov 18.

In recent years, the very high worldwide prevalence of chronic kidney disease (CKD) has led some authors to talk of an "epidemic." The progression of CKD varies considerably among individuals despite similar aetiologies, optimal blood pressure, and glycaemic control....

Effect of Different Disease-Modifying Therapies on Humoral Response to BNT162b2 Vaccine in Sardinian Multiple Sclerosis Patients.

Frontiers in immunology

Pitzalis M, Idda ML, Lodde V, Loizedda A, Lobina M, Zoledziewska M, Virdis F, Delogu G, Pirinu F, Marini MG, Mingoia M, Frau J, Lorefice L, Fronza M, Carmagnini D, Carta E, Orrù V, Uzzau S, Solla P, Loi F, Devoto M, Steri M, Fiorillo E, Floris M, Zarbo IR, Cocco E, Cucca F.
PMID: 34956211
Front Immunol. 2021 Dec 09;12:781843. doi: 10.3389/fimmu.2021.781843. eCollection 2021.

OBJECTIVES: Vaccination against COVID-19 is highly recommended to patients affected by multiple sclerosis (MS); however, the impact of MS disease-modifying therapies (DMTs) on the immune response following vaccination has been only partially investigated. Here, we aimed to elucidate the...

Effect of Different Disease-Modifying Therapies on Humoral Response to BNT162b2 Vaccine in Sardinian Multiple Sclerosis Patients.

Frontiers in immunology

Pitzalis M, Idda ML, Lodde V, Loizedda A, Lobina M, Zoledziewska M, Virdis F, Delogu G, Pirinu F, Marini MG, Mingoia M, Frau J, Lorefice L, Fronza M, Carmagnini D, Carta E, Orrù V, Uzzau S, Solla P, Loi F, Devoto M, Steri M, Fiorillo E, Floris M, Zarbo IR, Cocco E, Cucca F.
PMID: 34956211
Front Immunol. 2021 Dec 09;12:781843. doi: 10.3389/fimmu.2021.781843. eCollection 2021.

OBJECTIVES: Vaccination against COVID-19 is highly recommended to patients affected by multiple sclerosis (MS); however, the impact of MS disease-modifying therapies (DMTs) on the immune response following vaccination has been only partially investigated. Here, we aimed to elucidate the...

The Relationship of Transforming Growth Factor-β1 Gene Polymorphism, Its Plasma Level, and Gingival Overgrowth in Renal Transplant Recipients Receiving Different Immunosuppressive Regimens.

Journal of periodontology

Radwan-Oczko M, Boratyńska M, Ziętek M, Zołędziewska M, Jonkisz A.
PMID: 29539165
J Periodontol. 2006 May;77(5):865-873. doi: 10.1902/jop.2006.050086.

BACKGROUND: Cyclosporin A (CsA) induces gingival overgrowth (GO) in patients who seem to be prone to this disorder. It is still impossible to determine which patients will develop GO. Patients treated with the new immunosuppressive drug tacrolimus seem not...

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.

PloS one

de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM, Oldmeadow C, Mazur J, Basu S, Frånberg M, Yang Q, Ligthart S, Hottenga JJ, Rumley A, Mulas A, de Craen AJ, Grotevendt A, Taylor KD, Delgado GE, Kifley A, Lopez LM, Berentzen TL, Mangino M, Bandinelli S, Morrison AC, Hamsten A, Tofler G, de Maat MP, Draisma HH, Lowe GD, Zoledziewska M, Sattar N, Lackner KJ, Völker U, McKnight B, Huang J, Holliday EG, McEvoy MA, Starr JM, Hysi PG, Hernandez DG, Guan W, Rivadeneira F, McArdle WL, Slagboom PE, Zeller T, Psaty BM, Uitterlinden AG, de Geus EJ, Stott DJ, Binder H, Hofman A, Franco OH, Rotter JI, Ferrucci L, Spector TD, Deary IJ, März W, Greinacher A, Wild PS, Cucca F, Boomsma DI, Watkins H, Tang W, Ridker PM, Jukema JW, Scott RJ, Mitchell P, Hansen T, O'Donnell CJ, Smith NL, Strachan DP, Dehghan A.
PMID: 28107422
PLoS One. 2017 Jan 20;12(1):e0167742. doi: 10.1371/journal.pone.0167742. eCollection 2017.

An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associated loci when compared...

Showing 1 to 9 of 9 entries