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Showing 1 to 12 of 210 entries
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Lymphangiogenesis and angiogenesis during human fetal pancreas development.

Vascular cell

Roost MS, van Iperen L, de Melo Bernardo A, Mummery CL, Carlotti F, de Koning EJ, Chuva de Sousa Lopes SM.
PMID: 25785186
Vasc Cell. 2014 Nov 01;6:22. doi: 10.1186/2045-824X-6-22. eCollection 2014.

BACKGROUND: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and in...

On the stabilization of carbanions by adjacent phenyl, cyano, methoxy-carbonyl, and nitro groups in the gas phase.

Journal of the American Society for Mass Spectrometry

Peerboom RA, de Koning LJ, Nibbering NM.
PMID: 24222545
J Am Soc Mass Spectrom. 1994 Mar;5(3):159-68. doi: 10.1016/1044-0305(94)85029-1.

Institute of Mass Spectrometry, University of Amsterdam, Amsterdam, The Netherlands By using the method of Fourier transform ion cyclotron resonance mass spectrometry, substituent stabilization energies of homologous series of cycloalkyl carbanions, Ξ-c-CnH2n-2 (n = 3, 4, 5, 6, 7)...

Hematopoiesis: Gap Junction Intercellular Communication is Likely to be Involved in Regulation of Stroma-dependent Proliferation of Hemopoietic Stem Cells.

Hematology (Amsterdam, Netherlands)

Ploemacher RE, Mayen AE, De Koning AE, Krenacs T, Rosendaal M.
PMID: 11399609
Hematology. 2000;5(2):133-147. doi: 10.1080/10245332.2000.11746498.

The 80-100 fold increased immunohistological expression of the Gap Junction (GJ) protein Connexin-43 in murine bone marrow during the neonatal period and directly following cytoreductive treatment of adult mice suggests that the regulation of stem cell proliferation may involve...

Single-substrate liquid-crystal displays by photo-enforced stratification.

Nature

Penterman R, Klink SI, de Koning H, Nisato G, Broer DJ.
PMID: 11986663
Nature. 2002 May 02;417(6884):55-8. doi: 10.1038/417055a.

Data visualization plays a crucial role in our society, as illustrated by the many displays that surround us. In the future, displays may become even more pervasive, ranging from individually addressable image-rendering wall hangings to data displays integrated in...

Preparation and reductive transformations of vinylogous sulfonamides (beta-sulfonyl enamines), and application to the synthesis of indolizidines.

Organic & biomolecular chemistry

Michael JP, de Koning CB, Malefetse TJ, Yillah I.
PMID: 15565245
Org Biomol Chem. 2004 Dec 07;2(23):3510-7. doi: 10.1039/b413379j. Epub 2004 Nov 04.

Condensation between the methiodide salts of 1-alkylpyrrolidine-2-thiones and ethyl [(4-methylphenyl)sulfonyl]acetate or 1-[(4-methylphenyl)sulfonyl]propan-2-one afforded several 2-[[(4-methylphenyl)sulfonyl]methylene]pyrrolidines in good yield. These beta-sulfonyl enamines are sufficiently nucleophilic for cyclisation with internal electrophiles to give sulfone-substituted indolizines, potentially useful scaffolds for alkaloid synthesis....

Extensive QTL and association analyses of the QTLMAS2009 Data.

BMC proceedings

Hadjipavlou G, Hemani G, Leach R, Louro B, Nadaf J, Rowe S, de Koning DJ.
PMID: 20380754
BMC Proc. 2010 Mar 31;4:S11. doi: 10.1186/1753-6561-4-s1-s11.

BACKGROUND: We applied a range of genome-wide association (GWA) methods to map quantitative trait loci (QTL) in the simulated dataset provided by the QTLMAS2009 workshop to derive a comprehensive set of results. A Gompertz curve was modelled on the...

Urban air pollution worldwide.

Environmental science & technology

Bennett BG, Kretzschmar JG, Skland GG, de Koning HW.
PMID: 22283338
Environ Sci Technol. 1985 Apr 01;19(4):298-304. doi: 10.1021/es00134a603.

No abstract available.

High incidence of symptomatic hyperammonemia in children with acute lymphoblastic leukemia receiving pegylated asparaginase.

JIMD reports

Heitink-Pollé KM, Prinsen BH, de Koning TJ, van Hasselt PM, Bierings MB.
PMID: 23430503
JIMD Rep. 2013;7:103-8. doi: 10.1007/8904_2012_156. Epub 2012 Jul 01.

Asparaginase is a mainstay of treatment of childhood acute lymphoblastic leukemia. Pegylation of asparaginase extends its biological half-life and has been introduced in the newest treatment protocols aiming to further increase treatment success. Hyperammonemia is a recognized side effect...

Efficiency of direct selection on quantitative trait loci for a two-trait breeding objective.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

de Koning GJ, Weller JI.
PMID: 24186161
Theor Appl Genet. 1994 Aug;88(6):669-77. doi: 10.1007/BF01253969.

Selection on known loci affecting quantitative traits (DSQ) was compared to phenotypic selection index for a single and a two-trait selection objective. Two situations were simulated; a single known quantitative locus, and ten identified loci accounting for all the...

(±)-3-Benz-yloxy-1-(4-meth-oxy-benz-yl)piperidine-2-thione.

Acta crystallographica. Section E, Structure reports online

Pienaar DP, Khorasani S, de Koning CB, Michael JP.
PMID: 23476409
Acta Crystallogr Sect E Struct Rep Online. 2013 Jan 01;69:o21. doi: 10.1107/S1600536812048854. Epub 2012 Dec 05.

The title mol-ecule, C20H23NO2S, adopts a twisted conformation in which the two aromatic rings connected to the central piperidine ring are orientated trans to each other. An intra-molecular C-H⋯S contact occurs. In the crystal, C-H⋯π and C-H⋯O inter-actions act...

Quality of life of Hurler syndrome patients after successful hematopoietic stem cell transplantation.

Blood advances

Aldenhoven M, van den Broek BTA, Wynn RF, O'Meara A, Veys P, Rovelli A, Jones SA, Parini R, van Hasselt PM, Renard M, Bordon V, de Koning TJ, Boelens JJ.
PMID: 29296871
Blood Adv. 2017 Nov 07;1(24):2236-2242. doi: 10.1182/bloodadvances.2017011387. eCollection 2017 Nov 14.

Hurler syndrome (HS) is a lysosomal storage disease characterized by multisystem morbidity and death in early childhood. Hematopoietic stem cell transplantation (HSCT) results in long-term survival, although with significant residual disease burden. How this residual disease affects the health-related...

Exercise intensity modulates capillary perfusion in correspondence with ACE I/D modulated serum angiotensin II levels.

Applied & translational genomics

van Ginkel S, de Haan A, Woerdeman J, Vanhees L, Serné E, de Koning J, Flück M.
PMID: 26937347
Appl Transl Genom. 2015 Mar 27;4:33-7. doi: 10.1016/j.atg.2015.03.002. eCollection 2015 Mar.

During exercise the renin-angiotensin system is stimulated. We hypothesized that the increase in serum angiotensin II (AngII) levels after exercise is dependent on exercise intensity and duration and secondly that people with the ACE-II genotype will show a higher...

Showing 1 to 12 of 210 entries