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Antidepressant activity of fingolimod in mice.

Pharmacology research & perspectives

di Nuzzo L, Orlando R, Tognoli C, Di Pietro P, Bertini G, Miele J, Bucci D, Motolese M, Scaccianoce S, Caruso A, Mauro G, De Lucia C, Battaglia G, Bruno V, Fabene PF, Nicoletti F.
PMID: 26171219
Pharmacol Res Perspect. 2015 Jun;3(3):e00135. doi: 10.1002/prp2.135. Epub 2015 May 24.

Recent findings indicate that fingolimod, the first oral drug approved for the treatment of multiple sclerosis (MS), acts as a direct inhibitor of histone deacetylases (HDACs) and enhances the production of brain-derived neurotrophic factor (BDNF) in the CNS. Both...

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di Nuzzo L, Orlando R, Tognoli C, et al. Antidepressant activity of fingolimod in mice. Pharmacol Res Perspect. 2015;3(3):e00135doi: 10.1002/prp2.135.
di Nuzzo, L., Orlando, R., Tognoli, C., Di Pietro, P., Bertini, G., Miele, J., Bucci, D., Motolese, M., Scaccianoce, S., Caruso, A., Mauro, G., De Lucia, C., Battaglia, G., Bruno, V., Fabene, P. F., & Nicoletti, F. (2015). Antidepressant activity of fingolimod in mice. Pharmacology research & perspectives, 3(3), e00135. https://doi.org/10.1002/prp2.135
di Nuzzo, Luigi, et al. "Antidepressant activity of fingolimod in mice." Pharmacology research & perspectives vol. 3,3 (2015): e00135. doi: https://doi.org/10.1002/prp2.135
di Nuzzo L, Orlando R, Tognoli C, Di Pietro P, Bertini G, Miele J, Bucci D, Motolese M, Scaccianoce S, Caruso A, Mauro G, De Lucia C, Battaglia G, Bruno V, Fabene PF, Nicoletti F. Antidepressant activity of fingolimod in mice. Pharmacol Res Perspect. 2015 Jun;3(3):e00135. doi: 10.1002/prp2.135. Epub 2015 May 24. PMID: 26171219; PMCID: PMC4492751.
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Improving the Stability and Performance of Perovskite Light-Emitting Diodes by Thermal Annealing Treatment.

Advanced materials (Deerfield Beach, Fla.)

Yu JC, Kim DW, Kim da B, Jung ED, Park JH, Lee AY, Lee BR, Di Nuzzo D, Friend RH, Song MH.
PMID: 27239729
Adv Mater. 2016 Aug;28(32):6906-13. doi: 10.1002/adma.201601105. Epub 2016 May 30.

A perovskite LED with a perovskite film treated under optimum thermal annealing conditions exhibits a significantly enhanced long-term stability with full coverage of the green electroluminescence emission due to the highly uniform morphology of the perovskite film.

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Yu JC, Kim DW, Kim da B, et al. Improving the Stability and Performance of Perovskite Light-Emitting Diodes by Thermal Annealing Treatment. Adv Mater. 2016;28(32):6906-13doi: 10.1002/adma.201601105.
Yu, J. C., Kim, D. W., Kim, d. a. . B., Jung, E. D., Park, J. H., Lee, A. Y., Lee, B. R., Di Nuzzo, D., Friend, R. H., & Song, M. H. (2016). Improving the Stability and Performance of Perovskite Light-Emitting Diodes by Thermal Annealing Treatment. Advanced materials (Deerfield Beach, Fla.), 28(32), 6906-13. https://doi.org/10.1002/adma.201601105
Yu, Jae Choul, et al. "Improving the Stability and Performance of Perovskite Light-Emitting Diodes by Thermal Annealing Treatment." Advanced materials (Deerfield Beach, Fla.) vol. 28,32 (2016): 6906-13. doi: https://doi.org/10.1002/adma.201601105
Yu JC, Kim DW, Kim da B, Jung ED, Park JH, Lee AY, Lee BR, Di Nuzzo D, Friend RH, Song MH. Improving the Stability and Performance of Perovskite Light-Emitting Diodes by Thermal Annealing Treatment. Adv Mater. 2016 Aug;28(32):6906-13. doi: 10.1002/adma.201601105. Epub 2016 May 30. PMID: 27239729.
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Post 9-11 employee & business protection.

Occupational health & safety (Waco, Tex.)

DiNuzzo J.
PMID: 15382632
Occup Health Saf. 2004 Aug;73(8):66, 68, 89.

No abstract available.

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DiNuzzo J. Post 9-11 employee & business protection. Occup Health Saf. 2004;73(8):66, 68, 89
DiNuzzo, J. (2004). Post 9-11 employee & business protection. Occupational health & safety (Waco, Tex.), 73(8), 66, 68, 89.
DiNuzzo, John. "Post 9-11 employee & business protection." Occupational health & safety (Waco, Tex.) vol. 73,8 (2004): 66, 68, 89.
DiNuzzo J. Post 9-11 employee & business protection. Occup Health Saf. 2004 Aug;73(8):66, 68, 89. PMID: 15382632.
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Osteoporosis and cardiovascular diseases' cosegregation: epidemiological features.

Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases

Piscitelli P, Iolascon G, Gimigliano F, Gimigliano A, Marinelli A, Di Nuzzo R, Colì G, Di Paola L, Gianicolo E, Chitano G, Sbenaglia V, Gismondi R, Greco M, Camilli D, Modena MG, Brandi ML, Distante A, Cozma A.
PMID: 22460841
Clin Cases Miner Bone Metab. 2008 Jan;5(1):14-8.

Life expectancy in Italy is estimated to rise to 77.9 and 84.4 years in next years. Increased life expectancy is associated with a greater frailty of elderly people and an increased prevalence of chronic and degenerative illnesses such as...

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Piscitelli P, Iolascon G, Gimigliano F, et al. Osteoporosis and cardiovascular diseases' cosegregation: epidemiological features. Clin Cases Miner Bone Metab. 2008;5(1):14-8
Piscitelli, P., Iolascon, G., Gimigliano, F., Gimigliano, A., Marinelli, A., Di Nuzzo, R., Colì, G., Di Paola, L., Gianicolo, E., Chitano, G., Sbenaglia, V., Gismondi, R., Greco, M., Camilli, D., Modena, M. G., Brandi, M. L., Distante, A., & Cozma, A. (2008). Osteoporosis and cardiovascular diseases' cosegregation: epidemiological features. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases, 5(1), 14-8.
Piscitelli, Prisco, et al. "Osteoporosis and cardiovascular diseases' cosegregation: epidemiological features." Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases vol. 5,1 (2008): 14-8.
Piscitelli P, Iolascon G, Gimigliano F, Gimigliano A, Marinelli A, Di Nuzzo R, Colì G, Di Paola L, Gianicolo E, Chitano G, Sbenaglia V, Gismondi R, Greco M, Camilli D, Modena MG, Brandi ML, Distante A, Cozma A. Osteoporosis and cardiovascular diseases' cosegregation: epidemiological features. Clin Cases Miner Bone Metab. 2008 Jan;5(1):14-8. PMID: 22460841; PMCID: PMC2781189.
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Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia

Gisondi P, Amerio P, Amoroso GF, Antonucci VA, Bardazzi F, Buongiorno MR, Bruni P, Campanati A, Caproni M, Carlesimo M, Carrera CG, Cianchino G, Cimmino G, Costanzo A, Cozzani E, Dapavo P, D'amico D, De Simone C, Del Giglio M, Di Nuzzo S, Gai F, Galluccio AG, Goffredo A, Gualdi G, Guarneri C, Kokelj F, Lasagni C, Loconsole F, Longo V, Malagoli P, Miracapillo A, Mugheddu C, Parodi A, Pellegrino M, Peserico A, Piaserico S, Pistone G, Potenza C, Plumari A, Stingeni L, Strippoli D, Travaglino M, Girolomoni G.
PMID: 24675369
G Ital Dermatol Venereol. 2013 Dec;148(6):1-10.

AIM: The aim of this study was to provide practical recommendations for optimizing the use of conventional and biological systemic treatments for moderate-severe chronic plaque psoriasis, particularly in case of transitioning and switching.METHODS: A total number of 147 dermatologists...

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Gisondi P, Amerio P, Amoroso GF, et al. Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning. G Ital Dermatol Venereol. 2013;148(6):1-10
Gisondi, P., Amerio, P., Amoroso, G. F., Antonucci, V. A., Bardazzi, F., Buongiorno, M. R., Bruni, P., Campanati, A., Caproni, M., Carlesimo, M., Carrera, C. G., Cianchino, G., Cimmino, G., Costanzo, A., Cozzani, E., Dapavo, P., D'amico, D., De Simone, C., Del Giglio, M., Di Nuzzo, S., Gai, F., Galluccio, A. G., Goffredo, A., Gualdi, G., Guarneri, C., Kokelj, F., Lasagni, C., Loconsole, F., Longo, V., Malagoli, P., Miracapillo, A., Mugheddu, C., Parodi, A., Pellegrino, M., Peserico, A., Piaserico, S., Pistone, G., Potenza, C., Plumari, A., Stingeni, L., Strippoli, D., Travaglino, M., & Girolomoni, G. (2013). Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 148(6), 1-10.
Gisondi, P, et al. "Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning." Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia vol. 148,6 (2013): 1-10.
Gisondi P, Amerio P, Amoroso GF, Antonucci VA, Bardazzi F, Buongiorno MR, Bruni P, Campanati A, Caproni M, Carlesimo M, Carrera CG, Cianchino G, Cimmino G, Costanzo A, Cozzani E, Dapavo P, D'amico D, De Simone C, Del Giglio M, Di Nuzzo S, Gai F, Galluccio AG, Goffredo A, Gualdi G, Guarneri C, Kokelj F, Lasagni C, Loconsole F, Longo V, Malagoli P, Miracapillo A, Mugheddu C, Parodi A, Pellegrino M, Peserico A, Piaserico S, Pistone G, Potenza C, Plumari A, Stingeni L, Strippoli D, Travaglino M, Girolomoni G. Optimization of systemic treatments for chronic plaque psoriasis. Recommendations for switching and transitioning. G Ital Dermatol Venereol. 2013 Dec;148(6):1-10. PMID: 24675369.
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Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release.

Pharmaceutics

Adrover A, Paolicelli P, Petralito S, Di Muzio L, Trilli J, Cesa S, Tho I, Casadei MA.
PMID: 30999609
Pharmaceutics. 2019 Apr 17;11(4). doi: 10.3390/pharmaceutics11040187.

In this study, gellan gum (GG), a natural polysaccharide, was used to fabricate spherical porous beads suitable as sustained drug delivery systems for oral administration. GG was cross-linked with calcium ions to prepare polymeric beads. Rheological studies and preliminary...

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Adrover A, Paolicelli P, Petralito S, et al. Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release. Pharmaceutics. 2019;11(4)doi: 10.3390/pharmaceutics11040187.
Adrover, A., Paolicelli, P., Petralito, S., Di Muzio, L., Trilli, J., Cesa, S., Tho, I., & Casadei, M. A. (2019). Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release. Pharmaceutics, 11(4), . https://doi.org/10.3390/pharmaceutics11040187
Adrover, Alessandra, et al. "Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release." Pharmaceutics vol. 11,4 (2019). doi: https://doi.org/10.3390/pharmaceutics11040187
Adrover A, Paolicelli P, Petralito S, Di Muzio L, Trilli J, Cesa S, Tho I, Casadei MA. Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release. Pharmaceutics. 2019 Apr 17;11(4). doi: 10.3390/pharmaceutics11040187. PMID: 30999609; PMCID: PMC6523394.
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High Circular Polarization of Electroluminescence Achieved via Self-Assembly of a Light-Emitting Chiral Conjugated Polymer into Multidomain Cholesteric Films.

ACS nano

Di Nuzzo D, Kulkarni C, Zhao B, Smolinsky E, Tassinari F, Meskers SCJ, Naaman R, Meijer EW, Friend RH.
PMID: 29182859
ACS Nano. 2017 Dec 26;11(12):12713-12722. doi: 10.1021/acsnano.7b07390. Epub 2017 Dec 01.

We demonstrate a facile route to obtain high and broad-band circular polarization of electroluminescence in single-layer polymer OLEDs. As a light-emitting material we use a donor-acceptor polyfluorene with enantiomerically pure chiral side-chains. We show that upon thermal annealing the...

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Di Nuzzo D, Kulkarni C, Zhao B, et al. High Circular Polarization of Electroluminescence Achieved via Self-Assembly of a Light-Emitting Chiral Conjugated Polymer into Multidomain Cholesteric Films. ACS Nano. 2017;11(12):12713-12722doi: 10.1021/acsnano.7b07390.
Di Nuzzo, D., Kulkarni, C., Zhao, B., Smolinsky, E., Tassinari, F., Meskers, S. C. J., Naaman, R., Meijer, E. W., & Friend, R. H. (2017). High Circular Polarization of Electroluminescence Achieved via Self-Assembly of a Light-Emitting Chiral Conjugated Polymer into Multidomain Cholesteric Films. ACS nano, 11(12), 12713-12722. https://doi.org/10.1021/acsnano.7b07390
Di Nuzzo, Daniele, et al. "High Circular Polarization of Electroluminescence Achieved via Self-Assembly of a Light-Emitting Chiral Conjugated Polymer into Multidomain Cholesteric Films." ACS nano vol. 11,12 (2017): 12713-12722. doi: https://doi.org/10.1021/acsnano.7b07390
Di Nuzzo D, Kulkarni C, Zhao B, Smolinsky E, Tassinari F, Meskers SCJ, Naaman R, Meijer EW, Friend RH. High Circular Polarization of Electroluminescence Achieved via Self-Assembly of a Light-Emitting Chiral Conjugated Polymer into Multidomain Cholesteric Films. ACS Nano. 2017 Dec 26;11(12):12713-12722. doi: 10.1021/acsnano.7b07390. Epub 2017 Dec 01. PMID: 29182859.
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Multiscale Imaging Approach for Studying the Central Nervous System: Methodology and Perspective.

Frontiers in neuroscience

Fratini M, Abdollahzadeh A, DiNuzzo M, Salo RA, Maugeri L, Cedola A, Giove F, Gröhn O, Tohka J, Sierra A.
PMID: 32116518
Front Neurosci. 2020 Feb 07;14:72. doi: 10.3389/fnins.2020.00072. eCollection 2020.

Non-invasive imaging methods have become essential tools for understanding the central nervous system (CNS) in health and disease. In particular, magnetic resonance imaging (MRI) techniques provide information about the anatomy, microstructure, and function of the brain and spinal cord

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Fratini M, Abdollahzadeh A, DiNuzzo M, et al. Multiscale Imaging Approach for Studying the Central Nervous System: Methodology and Perspective. Front Neurosci. 2020;14:72doi: 10.3389/fnins.2020.00072.
Fratini, M., Abdollahzadeh, A., DiNuzzo, M., Salo, R. A., Maugeri, L., Cedola, A., Giove, F., Gröhn, O., Tohka, J., & Sierra, A. (2020). Multiscale Imaging Approach for Studying the Central Nervous System: Methodology and Perspective. Frontiers in neuroscience, 1472. https://doi.org/10.3389/fnins.2020.00072
Fratini, Michela, et al. "Multiscale Imaging Approach for Studying the Central Nervous System: Methodology and Perspective." Frontiers in neuroscience vol. 14 (2020): 72. doi: https://doi.org/10.3389/fnins.2020.00072
Fratini M, Abdollahzadeh A, DiNuzzo M, Salo RA, Maugeri L, Cedola A, Giove F, Gröhn O, Tohka J, Sierra A. Multiscale Imaging Approach for Studying the Central Nervous System: Methodology and Perspective. Front Neurosci. 2020 Feb 07;14:72. doi: 10.3389/fnins.2020.00072. eCollection 2020. PMID: 32116518; PMCID: PMC7019007.
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Astrophobic Axions.

Physical review letters

Di Luzio L, Mescia F, Nardi E, Panci P, Ziegler R.
PMID: 30004778
Phys Rev Lett. 2018 Jun 29;120(26):261803. doi: 10.1103/PhysRevLett.120.261803.

We propose a class of axion models with generation-dependent Peccei-Quinn charges for the known fermions that allow one to suppress the axion couplings to nucleons and electrons. Astrophysical limits are thus relaxed, allowing for axion masses up to O(0.1)...

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Di Luzio L, Mescia F, Nardi E, et al. Astrophobic Axions. Phys Rev Lett. 2018;120(26):261803doi: 10.1103/PhysRevLett.120.261803.
Di Luzio, L., Mescia, F., Nardi, E., Panci, P., & Ziegler, R. (2018). Astrophobic Axions. Physical review letters, 120(26), 261803. https://doi.org/10.1103/PhysRevLett.120.261803
Di Luzio, Luca, et al. "Astrophobic Axions." Physical review letters vol. 120,26 (2018): 261803. doi: https://doi.org/10.1103/PhysRevLett.120.261803
Di Luzio L, Mescia F, Nardi E, Panci P, Ziegler R. Astrophobic Axions. Phys Rev Lett. 2018 Jun 29;120(26):261803. doi: 10.1103/PhysRevLett.120.261803. PMID: 30004778.
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Breakdown of Chiral Perturbation Theory for the Axion Hot Dark Matter Bound.

Physical review letters

Di Luzio L, Martinelli G, Piazza G.
PMID: 34213927
Phys Rev Lett. 2021 Jun 18;126(24):241801. doi: 10.1103/PhysRevLett.126.241801.

We show that the commonly adopted hot dark matter bound on the axion mass m_{a}≲1  eV is not reliable, since it is obtained by extrapolating the chiral expansion in a region where the effective field theory breaks down. This...

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Di Luzio L, Martinelli G, Piazza G. Breakdown of Chiral Perturbation Theory for the Axion Hot Dark Matter Bound. Phys Rev Lett. 2021;126(24):241801doi: 10.1103/PhysRevLett.126.241801.
Di Luzio, L., Martinelli, G., & Piazza, G. (2021). Breakdown of Chiral Perturbation Theory for the Axion Hot Dark Matter Bound. Physical review letters, 126(24), 241801. https://doi.org/10.1103/PhysRevLett.126.241801
Di Luzio, Luca, et al. "Breakdown of Chiral Perturbation Theory for the Axion Hot Dark Matter Bound." Physical review letters vol. 126,24 (2021): 241801. doi: https://doi.org/10.1103/PhysRevLett.126.241801
Di Luzio L, Martinelli G, Piazza G. Breakdown of Chiral Perturbation Theory for the Axion Hot Dark Matter Bound. Phys Rev Lett. 2021 Jun 18;126(24):241801. doi: 10.1103/PhysRevLett.126.241801. PMID: 34213927.
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Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S.
PMID: 34994222
J Cereb Blood Flow Metab. 2022 Jan 07;271678X211064399. doi: 10.1177/0271678X211064399. Epub 2022 Jan 07.

Over the last two decades, it has been established that glucose metabolic fluxes in neurons and astrocytes are proportional to the rates of the glutamate/GABA-glutamine neurotransmitter cycles in close to 1:1 stoichiometries across a wide range of functional energy...

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Rothman DL, Dienel GA, Behar KL, et al. Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. J Cereb Blood Flow Metab. 2022;271678X211064399doi: 10.1177/0271678X211064399.
Rothman, D. L., Dienel, G. A., Behar, K. L., Hyder, F., DiNuzzo, M., Giove, F., & Mangia, S. (2022). Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 271678X211064399. https://doi.org/10.1177/0271678X211064399
Rothman, Douglas L, et al. "Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism vol. (2022): 271678X211064399. doi: https://doi.org/10.1177/0271678X211064399
Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S. Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission. J Cereb Blood Flow Metab. 2022 Jan 07;271678X211064399. doi: 10.1177/0271678X211064399. Epub 2022 Jan 07. PMID: 34994222.
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Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience.

Annals of vascular surgery

Bracale U, Di Nuzzo MM, Bracale UM, Del Guercio L, Panagrosso M, Serra R, Terracciano RM, De Werra C, Corcione F, Peltrini R, Sodo M.
PMID: 34492315
Ann Vasc Surg. 2022 Jan;78:226-232. doi: 10.1016/j.avsg.2021.07.009. Epub 2021 Sep 04.

BACKGROUND: The surgical management of concomitant occurrence of abdominal aortic aneurysm (AAA) and colorectal cancer (CRC) is still controversial. Conversely, benefits from a minimally invasive approach are well known concerning the treatment of both AAA and CRC. The aim...

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Bracale U, Di Nuzzo MM, Bracale UM, et al. Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience. Ann Vasc Surg. 2021;78:226-232doi: 10.1016/j.avsg.2021.07.009.
Bracale, U., Di Nuzzo, M. M., Bracale, U. M., Del Guercio, L., Panagrosso, M., Serra, R., Terracciano, R. M., De Werra, C., Corcione, F., Peltrini, R., & Sodo, M. (2022). Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience. Annals of vascular surgery, 78226-232. https://doi.org/10.1016/j.avsg.2021.07.009
Bracale, Umberto, et al. "Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience." Annals of vascular surgery vol. 78 (2022): 226-232. doi: https://doi.org/10.1016/j.avsg.2021.07.009
Bracale U, Di Nuzzo MM, Bracale UM, Del Guercio L, Panagrosso M, Serra R, Terracciano RM, De Werra C, Corcione F, Peltrini R, Sodo M. Sequential Minimally Invasive Treatment of Concomitant Abdominal Aortic Aneurysm and Colorectal Cancer: A Single-Center Experience. Ann Vasc Surg. 2022 Jan;78:226-232. doi: 10.1016/j.avsg.2021.07.009. Epub 2021 Sep 04. PMID: 34492315.
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