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Showing 1 to 5 of 5 entries
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Antimicrobial Prophylaxis and Modifications of the Gut Microbiota in Children with Cancer.

Antibiotics (Basel, Switzerland)

Bossù G, Di Sario R, Argentiero A, Esposito S.
PMID: 33546312
Antibiotics (Basel). 2021 Feb 03;10(2). doi: 10.3390/antibiotics10020152.

In children with cancer, chemotherapy can produce cytotoxic effects, resulting in immunosuppression and an augmented risk of febrile neutropenia and bloodstream infections. This has led to widespread use of antibiotic prophylaxis which, combined with intensive chemotherapy treatment, could have...

A Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment.

Cells

Hofer F, Di Sario G, Musiu C, Sartoris S, De Sanctis F, Ugel S.
PMID: 34685679
Cells. 2021 Oct 09;10(10). doi: 10.3390/cells10102700.

Myeloid-derived suppressor cells (MDSCs) constitute a plastic and heterogeneous cell population among immune cells within the tumour microenvironment (TME) that support cancer progression and resistance to therapy. During tumour progression, cancer cells modify their metabolism to sustain an increased...

Lipid peroxidation and paraoxonase-1 activity in celiac disease.

Journal of lipids

Ferretti G, Bacchetti T, Saturni L, Manzella N, Candelaresi C, Benedetti A, Di Sario A.
PMID: 22536510
J Lipids. 2012;2012:587479. doi: 10.1155/2012/587479. Epub 2012 Mar 25.

Paraoxonase-1 (PON1) plays an antioxidant and anti-inflammatory role. Aim of the study was to investigate the alteration of paraoxonase-1 activity in celiac disease (CD), an intestinal disorder characterized by toxic injury exerted by gluten peptides. Activities of PON1, levels...

Surfactant as modulating agent of enzyme-loaded liposome activity.

Biotechnology and bioengineering

Annesini MC, Braguglia CM, Memoli A, Palermiti LG, Di Sario S.
PMID: 18636484
Biotechnol Bioeng. 1997 Jul 20;55(2):261-6. doi: 10.1002/(SICI)1097-0290(19970720)55:2<261::AID-BIT3>3.0.CO;2-G.

Large phosphatydilcholine unilamellar vesicles appear to be suitable controlled and protective delivery systems of beta-galactosidase. Kinetic measurements carried out on intact loaded liposomes show that most of the enzyme is entrapped inside the liposomes and its activity is latent....

A Novel Monocyte Subset as a Unique Signature of Atherosclerotic Plaque Rupture.

Frontiers in cell and developmental biology

Vinci R, Pedicino D, Bonanni A, D'Aiello A, Severino A, Pisano E, Ponzo M, Canonico F, Ciampi P, Russo G, Di Sario M, Montone RA, Trani C, Conte C, Grimaldi MC, Cribari F, Massetti M, Crea F, Liuzzo G.
PMID: 34712669
Front Cell Dev Biol. 2021 Oct 12;9:753223. doi: 10.3389/fcell.2021.753223. eCollection 2021.

The evaluation of monocyte subset distribution among acute coronary syndrome (ACS) patients according to culprit coronary plaque morphology has never been explored. We evaluated whether there were significant differences in frequency of circulating monocyte subsets isolated from ACS patients...

Showing 1 to 5 of 5 entries