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Showing 1 to 12 of 14 entries
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Refining success of cardiac resynchronization therapy using a simple score predicting the amount of reverse ventricular remodelling: results from the Markers and Response to CRT (MARC) study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Maass AH, Vernooy K, Wijers SC, van 't Sant J, Cramer MJ, Meine M, Allaart CP, De Lange FJ, Prinzen FW, Gerritse B, Erdtsieck E, Scheerder COS, Hill MRS, Scholten M, Kloosterman M, Ter Horst IAH, Voors AA, Vos MA, Rienstra M, Van Gelder IC.
PMID: 28339818
Europace. 2018 Feb 01;20(2):e1-e10. doi: 10.1093/europace/euw445.

AIMS: Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in systolic heart failure patients with ventricular conduction delay. Variability of individual response to CRT warrants improved patient selection. The Markers and Response to CRT (MARC) study was designed to...

"Are CRT upgrade procedures more complex and associated with more complications than de novo CRT implantations?" A single centre experience.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Ter Horst IA, Kuijpers Y, van 't Sant J, Tuinenburg AE, Cramer MJ, Meine M.
PMID: 26643305
Neth Heart J. 2016 Jan;24(1):75-81. doi: 10.1007/s12471-015-0771-9.

OBJECTIVE: The objective of the study was to examine whether cardiac resynchronisation therapy upgrade procedures are more complex and associated with more complications than de novo implantations.METHOD: We retrospectively compared 134 upgrade procedures performed between 2006-2012 with a random,...

The risk of ventricular arrhythmias in a Dutch CRT population: CRT-defibrillator versus CRT-pacemaker.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Ter Horst IA, van 't Sant J, Wijers SC, Vos MA, Cramer MJ, Meine M.
PMID: 26797979
Neth Heart J. 2016 Mar;24(3):204-13. doi: 10.1007/s12471-015-0800-8.

BACKGROUND: Patients eligible for cardiac resynchronisation therapy (CRT) have an indication for primary prophylactic implantable cardioverter defibrillator (ICD) therapy. However, response to CRT might influence processes involved in arrhythmogenesis and therefore change the necessity of ICD therapy in certain...

Erratum to: Echocardiography and cardiac resynchronization therapy, friends or foes?.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

van Everdingen WM, Schipper JC, van 't Sant J, Misier KR, Meine M, Cramer MJ.
PMID: 26886921
Neth Heart J. 2016 Mar;24(3):221-4. doi: 10.1007/s12471-016-0807-9.

No abstract available.

Identification of Novel Neurocircuitry Through Which Leptin Targets Multiple Inputs to the Dopamine System to Reduce Food Reward Seeking.

Biological psychiatry

Omrani A, de Vrind VAJ, Lodder B, Stoltenborg I, Kooij K, Wolterink-Donselaar IG, Luijendijk-Berg MCM, Garner KM, Van't Sant LJ, Rozeboom A, Dickson SL, Meye FJ, Adan RAH.
PMID: 33867112
Biol Psychiatry. 2021 Dec 15;90(12):843-852. doi: 10.1016/j.biopsych.2021.02.017. Epub 2021 Feb 23.

BACKGROUND: Leptin reduces the motivation to obtain food by modulating activity of the mesolimbic dopamine (DA) system upon presentation of cues that predict a food reward. Although leptin directly reduces the activity of ventral tegmental area (VTA) DA neurons,...

In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration.

Acta neuropathologica communications

Van't Sant LJ, White JJ, Hoeijmakers JHJ, Vermeij WP, Jaarsma D.
PMID: 34020718
Acta Neuropathol Commun. 2021 May 21;9(1):94. doi: 10.1186/s40478-021-01200-y.

Fluorescent staining of newly transcribed RNA via metabolic labelling with 5-ethynyluridine (EU) and click chemistry enables visualisation of changes in transcription, such as in conditions of cellular stress. Here, we tested whether EU labelling can be used to examine...

Covered stent grafts for relining of chronically occluded femoro-popliteal bypasses in frail patients.

Clinical case reports

van Nistelrooij AMJ, van 't Sant HP, Schouten O.
PMID: 34430011
Clin Case Rep. 2021 Aug 16;9(8):e04647. doi: 10.1002/ccr3.4647. eCollection 2021 Aug.

In four high-risk patients with chronically occluded femoro-popliteal bypass suffering from Rutherford 4-5 chronic limb threatening ischemia we performed, as an alternative for redo surgery, endovasculair relining with covered stent grafts. During follow-up (3, 8, 14 and 20 months)...

Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding.

Frontiers in endocrinology

de Vrind VAJ, van 't Sant LJ, Rozeboom A, Luijendijk-Berg MCM, Omrani A, Adan RAH.
PMID: 34276560
Front Endocrinol (Lausanne). 2021 Jul 01;12:680494. doi: 10.3389/fendo.2021.680494. eCollection 2021.

Leptin is an anorexigenic hormone, important in the regulation of body weight. Leptin plays a role in food reward, feeding, locomotion and anxiety. Leptin receptors (LepR) are expressed in many brain areas, including the midbrain. In most studies that...

Echo response and clinical outcome in CRT patients.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

van 't Sant J, Mast TP, Bos MM, Ter Horst IA, van Everdingen WM, Meine M, Cramer MJ.
PMID: 26643303
Neth Heart J. 2016 Jan;24(1):47-55. doi: 10.1007/s12471-015-0767-5.

BACKGROUND: Change in left ventricular end-systolic volume (∆LVESV) is the most frequently used surrogate marker in measuring response to cardiac resynchronisation therapy (CRT). We investigated whether ∆LVESV is the best measure to discriminate between a favourable and unfavourable outcome...

Echocardiography and cardiac resynchronisation therapy, friends or foes?.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

van Everdingen WM, Schipper JC, van 't Sant J, Ramdat Misier K, Meine M, Cramer MJ.
PMID: 26645707
Neth Heart J. 2016 Jan;24(1):25-38. doi: 10.1007/s12471-015-0769-3.

Echocardiography is used in cardiac resynchronisation therapy (CRT) to assess cardiac function, and in particular left ventricular (LV) volumetric status, and prediction of response. Despite its widespread applicability, LV volumes determined by echocardiography have inherent measurement errors, interobserver and...

Swinging beats: transient heart block in cardiac lymphoma.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Buikema JW, Goodyer WR, Koudstaal S, van 't Sant J, Verheggen PW, de Vrey EA, de Smet BJ.
PMID: 30039382
Neth Heart J. 2018 Sep;26(9):467-468. doi: 10.1007/s12471-018-1135-z.

No abstract available.

A "Stopper" mutant of Neurospora crassa containing two populations of aberrant mitochondrial DNA.

Current genetics

de Vries H, de Jonge JC, Van't Sant P, Agsteribbe E, Arnberg A.
PMID: 24190132
Curr Genet. 1981 Jul;3(3):205-11. doi: 10.1007/BF00429822.

[E35], an extranuclear mutant of Neurospora crassa has all the phenotypic characteristics of the "stopper" mutants (De Vries et al. 1980). In the present work, the mitochondrial DNA as well as the mitochondrial translation products are characterized further. The...

Showing 1 to 12 of 14 entries