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Showing 1 to 12 of 97 entries
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Human fetal liver cells for regulated ex vivo erythropoietin gene therapy.

Molecular therapy. Methods & clinical development

El Filali E, Duijst S, Hiralall JK, Legrand N, van Gulik T, Hoekstra R, Seppen J.
PMID: 26015950
Mol Ther Methods Clin Dev. 2014 Mar 12;1:14003. doi: 10.1038/mtm.2014.3. eCollection 2014.

Possible risks and lack of donor livers limit application of liver transplantation. Liver cell transplantation is, at this moment, not a feasible alternative because engraftment in the liver is poor. Furthermore, there is also shortage of cells suitable for...

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El Filali E, Duijst S, Hiralall JK, et al. Human fetal liver cells for regulated ex vivo erythropoietin gene therapy. Mol Ther Methods Clin Dev. 2014;1:14003doi: 10.1038/mtm.2014.3.
El Filali, E., Duijst, S., Hiralall, J. K., Legrand, N., van Gulik, T., Hoekstra, R., & Seppen, J. (2014). Human fetal liver cells for regulated ex vivo erythropoietin gene therapy. Molecular therapy. Methods & clinical development, 114003. https://doi.org/10.1038/mtm.2014.3
El Filali, Ebtisam, et al. "Human fetal liver cells for regulated ex vivo erythropoietin gene therapy." Molecular therapy. Methods & clinical development vol. 1 (2014): 14003. doi: https://doi.org/10.1038/mtm.2014.3
El Filali E, Duijst S, Hiralall JK, Legrand N, van Gulik T, Hoekstra R, Seppen J. Human fetal liver cells for regulated ex vivo erythropoietin gene therapy. Mol Ther Methods Clin Dev. 2014 Mar 12;1:14003. doi: 10.1038/mtm.2014.3. eCollection 2014. PMID: 26015950; PMCID: PMC4362349.
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Survival after resection of perihilar cholangiocarcinoma-development and external validation of a prognostic nomogram.

Annals of oncology : official journal of the European Society for Medical Oncology

Groot Koerkamp B, Wiggers JK, Gonen M, Doussot A, Allen PJ, Besselink MG, Blumgart LH, Busch OR, D'Angelica MI, DeMatteo RP, Gouma DJ, Kingham TP, van Gulik TM, Jarnagin WR.
PMID: 26920702
Ann Oncol. 2016 Apr;27(4):753. doi: 10.1093/annonc/mdw063. Epub 2016 Feb 25.

No abstract available.

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Groot Koerkamp B, Wiggers JK, Gonen M, et al. Survival after resection of perihilar cholangiocarcinoma-development and external validation of a prognostic nomogram. Ann Oncol. 2016;27(4):753doi: 10.1093/annonc/mdw063.
Groot Koerkamp, B., Wiggers, J. K., Gonen, M., Doussot, A., Allen, P. J., Besselink, M. G., Blumgart, L. H., Busch, O. R., D'Angelica, M. I., DeMatteo, R. P., Gouma, D. J., Kingham, T. P., van Gulik, T. M., & Jarnagin, W. R. (2016). Survival after resection of perihilar cholangiocarcinoma-development and external validation of a prognostic nomogram. Annals of oncology : official journal of the European Society for Medical Oncology, 27(4), 753. https://doi.org/10.1093/annonc/mdw063
Groot Koerkamp, B, et al. "Survival after resection of perihilar cholangiocarcinoma-development and external validation of a prognostic nomogram." Annals of oncology : official journal of the European Society for Medical Oncology vol. 27,4 (2016): 753. doi: https://doi.org/10.1093/annonc/mdw063
Groot Koerkamp B, Wiggers JK, Gonen M, Doussot A, Allen PJ, Besselink MG, Blumgart LH, Busch OR, D'Angelica MI, DeMatteo RP, Gouma DJ, Kingham TP, van Gulik TM, Jarnagin WR. Survival after resection of perihilar cholangiocarcinoma-development and external validation of a prognostic nomogram. Ann Oncol. 2016 Apr;27(4):753. doi: 10.1093/annonc/mdw063. Epub 2016 Feb 25. PMID: 26920702; PMCID: PMC4803457.
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Kinetics and stoichiometry of growth of plant cell cultures of Catharanthus roseus and Nicotiana tabacum in batch and continuous fermentors.

Biotechnology and bioengineering

van Gulik WM, Ten Hoopen HJ, Heijnen JJ.
PMID: 18601193
Biotechnol Bioeng. 1992 Oct 20;40(8):863-74. doi: 10.1002/bit.260400802.

Plant cell suspension cultures of Catharanthus roseus and Nicotiana tabacum were grown in stirred tank bioreactors operated in batch and continuous mode. The stoichiometry of growth of both species in steady-state glucose limited chemostats was studied at a range...

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van Gulik WM, Ten Hoopen HJ, Heijnen JJ. Kinetics and stoichiometry of growth of plant cell cultures of Catharanthus roseus and Nicotiana tabacum in batch and continuous fermentors. Biotechnol Bioeng. 1992;40(8):863-74doi: 10.1002/bit.260400802.
van Gulik, W. M., Ten Hoopen, H. J., & Heijnen, J. J. (1992). Kinetics and stoichiometry of growth of plant cell cultures of Catharanthus roseus and Nicotiana tabacum in batch and continuous fermentors. Biotechnology and bioengineering, 40(8), 863-74. https://doi.org/10.1002/bit.260400802
van Gulik, W M, et al. "Kinetics and stoichiometry of growth of plant cell cultures of Catharanthus roseus and Nicotiana tabacum in batch and continuous fermentors." Biotechnology and bioengineering vol. 40,8 (1992): 863-74. doi: https://doi.org/10.1002/bit.260400802
van Gulik WM, Ten Hoopen HJ, Heijnen JJ. Kinetics and stoichiometry of growth of plant cell cultures of Catharanthus roseus and Nicotiana tabacum in batch and continuous fermentors. Biotechnol Bioeng. 1992 Oct 20;40(8):863-74. doi: 10.1002/bit.260400802. PMID: 18601193.
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Pancreatic carcinoma: palliative surgical and endoscopic treatment.

HPB : the official journal of the International Hepato Pancreato Biliary Association

Gouma DJ, Busch OR, Van Gulik TM.
PMID: 18333090
HPB (Oxford). 2006;8(5):369-76. doi: 10.1080/13651820600804021.

The majority of patients with pancreatic carcinoma (hepaticojejunostomy) unfortunately will have palliative treatment and palliation of symptoms is important to improve Quality of Life. The most common symptoms that require palliation are jaundice, gastric outlet obstruction and pain. Obstructive...

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Gouma DJ, Busch OR, Van Gulik TM. Pancreatic carcinoma: palliative surgical and endoscopic treatment. HPB (Oxford). 2006;8(5):369-76doi: 10.1080/13651820600804021.
Gouma, D. J., Busch, O. R., & Van Gulik, T. M. (2006). Pancreatic carcinoma: palliative surgical and endoscopic treatment. HPB : the official journal of the International Hepato Pancreato Biliary Association, 8(5), 369-76. https://doi.org/10.1080/13651820600804021
Gouma, D J, et al. "Pancreatic carcinoma: palliative surgical and endoscopic treatment." HPB : the official journal of the International Hepato Pancreato Biliary Association vol. 8,5 (2006): 369-76. doi: https://doi.org/10.1080/13651820600804021
Gouma DJ, Busch OR, Van Gulik TM. Pancreatic carcinoma: palliative surgical and endoscopic treatment. HPB (Oxford). 2006;8(5):369-76. doi: 10.1080/13651820600804021. PMID: 18333090; PMCID: PMC2020753.
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Cholestasis enhances liver ischemia/reperfusion-induced coagulation activation in rats.

Hepatology research : the official journal of the Japan Society of Hepatology

Kloek JJ, Levi M, Heger M, van der Loos CM, Gouma DJ, van Gulik TM.
PMID: 19737317
Hepatol Res. 2010 Feb;40(2):204-15. doi: 10.1111/j.1872-034X.2009.00579.x. Epub 2009 Sep 07.

AIM: Cholestasis is associated with increased morbidity and mortality in patients undergoing major liver surgery. An additional risk is induced when vascular inflow occlusion is applied giving rise to liver ischemia/reperfusion (I/R) injury. The role of the coagulation system...

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Kloek JJ, Levi M, Heger M, et al. Cholestasis enhances liver ischemia/reperfusion-induced coagulation activation in rats. Hepatol Res. 2009;40(2):204-15doi: 10.1111/j.1872-034X.2009.00579.x.
Kloek, J. J., Levi, M., Heger, M., van der Loos, C. M., Gouma, D. J., & van Gulik, T. M. (2010). Cholestasis enhances liver ischemia/reperfusion-induced coagulation activation in rats. Hepatology research : the official journal of the Japan Society of Hepatology, 40(2), 204-15. https://doi.org/10.1111/j.1872-034X.2009.00579.x
Kloek, Jaap J, et al. "Cholestasis enhances liver ischemia/reperfusion-induced coagulation activation in rats." Hepatology research : the official journal of the Japan Society of Hepatology vol. 40,2 (2010): 204-15. doi: https://doi.org/10.1111/j.1872-034X.2009.00579.x
Kloek JJ, Levi M, Heger M, van der Loos CM, Gouma DJ, van Gulik TM. Cholestasis enhances liver ischemia/reperfusion-induced coagulation activation in rats. Hepatol Res. 2010 Feb;40(2):204-15. doi: 10.1111/j.1872-034X.2009.00579.x. Epub 2009 Sep 07. PMID: 19737317.
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Development of quantitative metabolomics for Pichia pastoris.

Metabolomics : Official journal of the Metabolomic Society

Carnicer M, Canelas AB, Ten Pierick A, Zeng Z, van Dam J, Albiol J, Ferrer P, Heijnen JJ, van Gulik W.
PMID: 22448155
Metabolomics. 2012 Apr;8(2):284-298. doi: 10.1007/s11306-011-0308-1. Epub 2011 Apr 21.

Accurate, reliable and reproducible measurement of intracellular metabolite levels has become important for metabolic studies of microbial cell factories. A first critical step for metabolomic studies is the establishment of an adequate quenching and washing protocol, which ensures effective...

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Carnicer M, Canelas AB, Ten Pierick A, et al. Development of quantitative metabolomics for Pichia pastoris. Metabolomics. 2011;8(2):284-298doi: 10.1007/s11306-011-0308-1.
Carnicer, M., Canelas, A. B., Ten Pierick, A., Zeng, Z., van Dam, J., Albiol, J., Ferrer, P., Heijnen, J. J., & van Gulik, W. (2012). Development of quantitative metabolomics for Pichia pastoris. Metabolomics : Official journal of the Metabolomic Society, 8(2), 284-298. https://doi.org/10.1007/s11306-011-0308-1
Carnicer, Marc, et al. "Development of quantitative metabolomics for Pichia pastoris." Metabolomics : Official journal of the Metabolomic Society vol. 8,2 (2012): 284-298. doi: https://doi.org/10.1007/s11306-011-0308-1
Carnicer M, Canelas AB, Ten Pierick A, Zeng Z, van Dam J, Albiol J, Ferrer P, Heijnen JJ, van Gulik W. Development of quantitative metabolomics for Pichia pastoris. Metabolomics. 2012 Apr;8(2):284-298. doi: 10.1007/s11306-011-0308-1. Epub 2011 Apr 21. PMID: 22448155; PMCID: PMC3291848.
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Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines.

Journal of cell communication and signaling

van Wenum M, Adam AAA, van der Mark VA, Chang JC, Wildenberg ME, Hendriks EJ, Jongejan A, Moerland PD, van Gulik TM, Oude Elferink RP, Chamuleau RAFM, Hoekstra R.
PMID: 29399736
J Cell Commun Signal. 2018 Sep;12(3):575-588. doi: 10.1007/s12079-018-0456-4. Epub 2018 Feb 04.

The in vitro generation of terminally differentiated hepatocytes is an unmet need. We investigated the contribution of oxygen concentration to differentiation in human liver cell lines HepaRG and C3A. HepaRG cells were cultured under hypoxia (5%O

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van Wenum M, Adam AAA, van der Mark VA, et al. Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines. J Cell Commun Signal. 2018;12(3):575-588doi: 10.1007/s12079-018-0456-4.
van Wenum, M., Adam, A. A. A., van der Mark, V. A., Chang, J. C., Wildenberg, M. E., Hendriks, E. J., Jongejan, A., Moerland, P. D., van Gulik, T. M., Oude Elferink, R. P., Chamuleau, R. A. F. M., & Hoekstra, R. (2018). Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines. Journal of cell communication and signaling, 12(3), 575-588. https://doi.org/10.1007/s12079-018-0456-4
van Wenum, Martien, et al. "Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines." Journal of cell communication and signaling vol. 12,3 (2018): 575-588. doi: https://doi.org/10.1007/s12079-018-0456-4
van Wenum M, Adam AAA, van der Mark VA, Chang JC, Wildenberg ME, Hendriks EJ, Jongejan A, Moerland PD, van Gulik TM, Oude Elferink RP, Chamuleau RAFM, Hoekstra R. Oxygen drives hepatocyte differentiation and phenotype stability in liver cell lines. J Cell Commun Signal. 2018 Sep;12(3):575-588. doi: 10.1007/s12079-018-0456-4. Epub 2018 Feb 04. PMID: 29399736; PMCID: PMC6039343.
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Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series.

Journal of clinical and translational research

Agnass P, van Veldhuisen E, Vogel JA, Kok HP, de Keijzer MJ, Schooneveldt G, de Haan LR, Klaessens JH, Scheffer HJ, Meijerink MR, van Lienden KP, van Gulik TM, Heger M, Crezee J, Besselink MG.
PMID: 32617426
J Clin Transl Res. 2020 Mar 12;5(3):109-132. eCollection 2020 Apr 13.

AIMS: First, the aim of the study was to determine whether irreversible electroporation (IRE) is associated with heat generation in the liver and pancreas at clinical (≤1,500 V/cm) and supraclinical (>1,500 V/cm) electroporation settings; second, to assess the risk...

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Agnass P, van Veldhuisen E, Vogel JA, et al. Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series. J Clin Transl Res. 2020;5(3):109-132
Agnass, P., van Veldhuisen, E., Vogel, J. A., Kok, H. P., de Keijzer, M. J., Schooneveldt, G., de Haan, L. R., Klaessens, J. H., Scheffer, H. J., Meijerink, M. R., van Lienden, K. P., van Gulik, T. M., Heger, M., Crezee, J., & Besselink, M. G. (2020). Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series. Journal of clinical and translational research, 5(3), 109-132.
Agnass, Pierre, et al. "Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series." Journal of clinical and translational research vol. 5,3 (2020): 109-132.
Agnass P, van Veldhuisen E, Vogel JA, Kok HP, de Keijzer MJ, Schooneveldt G, de Haan LR, Klaessens JH, Scheffer HJ, Meijerink MR, van Lienden KP, van Gulik TM, Heger M, Crezee J, Besselink MG. Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series. J Clin Transl Res. 2020 Mar 12;5(3):109-132. eCollection 2020 Apr 13. PMID: 32617426; PMCID: PMC7326268.
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Correction to: Diffusion-weighted imaging for assessment of synovial inflammation in juvenile idiopathic arthritis: a promising imaging biomarker as an alternative to gadolinium-based contrast agents.

European radiology

Barendregt AM, van Gulik EC, Lavini C, Nusman CM, van den Berg JM, Schonenberg-Meinema D, Dolman KM, Kuijpers TW, Hemke R, Maas M.
PMID: 30506215
Eur Radiol. 2019 Jun;29(6):3319-3320. doi: 10.1007/s00330-018-5881-5.

The original version of this article, published on 12 June 2017, unfortunately contained a mistake.

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Barendregt AM, van Gulik EC, Lavini C, et al. Correction to: Diffusion-weighted imaging for assessment of synovial inflammation in juvenile idiopathic arthritis: a promising imaging biomarker as an alternative to gadolinium-based contrast agents. Eur Radiol. 2019;29(6):3319-3320doi: 10.1007/s00330-018-5881-5.
Barendregt, A. M., van Gulik, E. C., Lavini, C., Nusman, C. M., van den Berg, J. M., Schonenberg-Meinema, D., Dolman, K. M., Kuijpers, T. W., Hemke, R., & Maas, M. (2019). Correction to: Diffusion-weighted imaging for assessment of synovial inflammation in juvenile idiopathic arthritis: a promising imaging biomarker as an alternative to gadolinium-based contrast agents. European radiology, 29(6), 3319-3320. https://doi.org/10.1007/s00330-018-5881-5
Barendregt, Anouk M, et al. "Correction to: Diffusion-weighted imaging for assessment of synovial inflammation in juvenile idiopathic arthritis: a promising imaging biomarker as an alternative to gadolinium-based contrast agents." European radiology vol. 29,6 (2019): 3319-3320. doi: https://doi.org/10.1007/s00330-018-5881-5
Barendregt AM, van Gulik EC, Lavini C, Nusman CM, van den Berg JM, Schonenberg-Meinema D, Dolman KM, Kuijpers TW, Hemke R, Maas M. Correction to: Diffusion-weighted imaging for assessment of synovial inflammation in juvenile idiopathic arthritis: a promising imaging biomarker as an alternative to gadolinium-based contrast agents. Eur Radiol. 2019 Jun;29(6):3319-3320. doi: 10.1007/s00330-018-5881-5. PMID: 30506215; PMCID: PMC6828305.
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Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum.

Metabolomics : Official journal of the Metabolomic Society

de Jonge LP, Douma RD, Heijnen JJ, van Gulik WM.
PMID: 22833711
Metabolomics. 2012 Aug;8(4):727-735. doi: 10.1007/s11306-011-0367-3. Epub 2011 Oct 07.

A sampling procedure for quantitative metabolomics in Penicillium chrysogenum based on cold aqueous methanol quenching was re-evaluated and optimized to reduce metabolite leakage during sample treatment. The optimization study included amino acids and intermediates of the glycolysis and the...

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de Jonge LP, Douma RD, Heijnen JJ, et al. Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum. Metabolomics. 2011;8(4):727-735doi: 10.1007/s11306-011-0367-3.
de Jonge, L. P., Douma, R. D., Heijnen, J. J., & van Gulik, W. M. (2012). Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum. Metabolomics : Official journal of the Metabolomic Society, 8(4), 727-735. https://doi.org/10.1007/s11306-011-0367-3
de Jonge, Lodewijk P, et al. "Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum." Metabolomics : Official journal of the Metabolomic Society vol. 8,4 (2012): 727-735. doi: https://doi.org/10.1007/s11306-011-0367-3
de Jonge LP, Douma RD, Heijnen JJ, van Gulik WM. Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum. Metabolomics. 2012 Aug;8(4):727-735. doi: 10.1007/s11306-011-0367-3. Epub 2011 Oct 07. PMID: 22833711; PMCID: PMC3397231.
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Uncoupling growth and succinic acid production in an industrial Saccharomyces cerevisiae strain.

Biotechnology and bioengineering

Liu Y, Esen O, Pronk JT, van Gulik WM.
PMID: 33410171
Biotechnol Bioeng. 2021 Apr;118(4):1576-1586. doi: 10.1002/bit.27672. Epub 2021 Jan 21.

This study explores the relation between biomass-specific succinic acid (SA) production rate and specific growth rate of an engineered industrial strain of Saccharomyces cerevisiae, with the aim to investigate the extent to which growth and product formation can be...

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Liu Y, Esen O, Pronk JT, et al. Uncoupling growth and succinic acid production in an industrial Saccharomyces cerevisiae strain. Biotechnol Bioeng. 2021;118(4):1576-1586doi: 10.1002/bit.27672.
Liu, Y., Esen, O., Pronk, J. T., & van Gulik, W. M. (2021). Uncoupling growth and succinic acid production in an industrial Saccharomyces cerevisiae strain. Biotechnology and bioengineering, 118(4), 1576-1586. https://doi.org/10.1002/bit.27672
Liu, Yaya, et al. "Uncoupling growth and succinic acid production in an industrial Saccharomyces cerevisiae strain." Biotechnology and bioengineering vol. 118,4 (2021): 1576-1586. doi: https://doi.org/10.1002/bit.27672
Liu Y, Esen O, Pronk JT, van Gulik WM. Uncoupling growth and succinic acid production in an industrial Saccharomyces cerevisiae strain. Biotechnol Bioeng. 2021 Apr;118(4):1576-1586. doi: 10.1002/bit.27672. Epub 2021 Jan 21. PMID: 33410171; PMCID: PMC8048565.
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Staging Laparoscopy in Patients with Intrahepatic Cholangiocarcinoma: Is It Still Useful?.

Visceral medicine

Franken LC, Coelen RJS, Roos E, Verheij J, Phoa SS, Besselink MG, Busch ORC, van Gulik TM.
PMID: 33442552
Visc Med. 2020 Dec;36(6):501-505. doi: 10.1159/000506297. Epub 2020 Mar 03.

BACKGROUND: The role of staging laparoscopy in patients with intrahepatic cholangiocarcinoma remains unclear. Despite extensive preoperative imaging, approximately 25% of patients are deemed unresectable at laparotomy due to metastasized disease. The aim of this study was to evaluate the...

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Franken LC, Coelen RJS, Roos E, et al. Staging Laparoscopy in Patients with Intrahepatic Cholangiocarcinoma: Is It Still Useful?. Visc Med. 2020;36(6):501-505doi: 10.1159/000506297.
Franken, L. C., Coelen, R. J. S., Roos, E., Verheij, J., Phoa, S. S., Besselink, M. G., Busch, O. R. C., & van Gulik, T. M. (2020). Staging Laparoscopy in Patients with Intrahepatic Cholangiocarcinoma: Is It Still Useful?. Visceral medicine, 36(6), 501-505. https://doi.org/10.1159/000506297
Franken, Lotte C, et al. "Staging Laparoscopy in Patients with Intrahepatic Cholangiocarcinoma: Is It Still Useful?." Visceral medicine vol. 36,6 (2020): 501-505. doi: https://doi.org/10.1159/000506297
Franken LC, Coelen RJS, Roos E, Verheij J, Phoa SS, Besselink MG, Busch ORC, van Gulik TM. Staging Laparoscopy in Patients with Intrahepatic Cholangiocarcinoma: Is It Still Useful?. Visc Med. 2020 Dec;36(6):501-505. doi: 10.1159/000506297. Epub 2020 Mar 03. PMID: 33442552; PMCID: PMC7768138.
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Showing 1 to 12 of 97 entries