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Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.

Environmental toxicology and pharmacology

van Lipzig MM, Vermeulen NP, Gusinu R, Legler J, Frank H, Seidel A, Meerman JH.
PMID: 21783461
Environ Toxicol Pharmacol. 2005 Jan;19(1):41-55. doi: 10.1016/j.etap.2004.03.010.

Metabolism of polycyclic aromatic hydrocarbons (PAHs) has been studied intensively, and potential metabolites with estrogenic activity have been identified previously. However, little attention has been paid to the metabolic pathways in mammalians and to the combined effect of individual...

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van Lipzig MM, Vermeulen NP, Gusinu R, et al. Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. Environ Toxicol Pharmacol. 2005;19(1):41-55doi: 10.1016/j.etap.2004.03.010.
van Lipzig, M. M., Vermeulen, N. P., Gusinu, R., Legler, J., Frank, H., Seidel, A., & Meerman, J. H. (2005). Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. Environmental toxicology and pharmacology, 19(1), 41-55. https://doi.org/10.1016/j.etap.2004.03.010
van Lipzig, Marola M H, et al. "Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity." Environmental toxicology and pharmacology vol. 19,1 (2005): 41-55. doi: https://doi.org/10.1016/j.etap.2004.03.010
van Lipzig MM, Vermeulen NP, Gusinu R, Legler J, Frank H, Seidel A, Meerman JH. Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. Environ Toxicol Pharmacol. 2005 Jan;19(1):41-55. doi: 10.1016/j.etap.2004.03.010. PMID: 21783461.
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Clouds enhance Greenland ice sheet meltwater runoff.

Nature communications

Van Tricht K, Lhermitte S, Lenaerts JT, Gorodetskaya IV, L'Ecuyer TS, Noël B, van den Broeke MR, Turner DD, van Lipzig NP.
PMID: 26756470
Nat Commun. 2016 Jan 12;7:10266. doi: 10.1038/ncomms10266.

The Greenland ice sheet has become one of the main contributors to global sea level rise, predominantly through increased meltwater runoff. The main drivers of Greenland ice sheet runoff, however, remain poorly understood. Here we show that clouds enhance...

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Van Tricht K, Lhermitte S, Lenaerts JT, et al. Clouds enhance Greenland ice sheet meltwater runoff. Nat Commun. 2016;7:10266doi: 10.1038/ncomms10266.
Van Tricht, K., Lhermitte, S., Lenaerts, J. T., Gorodetskaya, I. V., L'Ecuyer, T. S., Noël, B., van den Broeke, M. R., Turner, D. D., & van Lipzig, N. P. (2016). Clouds enhance Greenland ice sheet meltwater runoff. Nature communications, 710266. https://doi.org/10.1038/ncomms10266
Van Tricht, K, et al. "Clouds enhance Greenland ice sheet meltwater runoff." Nature communications vol. 7 (2016): 10266. doi: https://doi.org/10.1038/ncomms10266
Van Tricht K, Lhermitte S, Lenaerts JT, Gorodetskaya IV, L'Ecuyer TS, Noël B, van den Broeke MR, Turner DD, van Lipzig NP. Clouds enhance Greenland ice sheet meltwater runoff. Nat Commun. 2016 Jan 12;7:10266. doi: 10.1038/ncomms10266. PMID: 26756470; PMCID: PMC4729937.
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Hazardous thunderstorm intensification over Lake Victoria.

Nature communications

Thiery W, Davin EL, Seneviratne SI, Bedka K, Lhermitte S, van Lipzig NP.
PMID: 27658848
Nat Commun. 2016 Sep 23;7:12786. doi: 10.1038/ncomms12786.

Weather extremes have harmful impacts on communities around Lake Victoria, where thousands of fishermen die every year because of intense night-time thunderstorms. Yet how these thunderstorms will evolve in a future warmer climate is still unknown. Here we show...

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Thiery W, Davin EL, Seneviratne SI, et al. Hazardous thunderstorm intensification over Lake Victoria. Nat Commun. 2016;7:12786doi: 10.1038/ncomms12786.
Thiery, W., Davin, E. L., Seneviratne, S. I., Bedka, K., Lhermitte, S., & van Lipzig, N. P. (2016). Hazardous thunderstorm intensification over Lake Victoria. Nature communications, 712786. https://doi.org/10.1038/ncomms12786
Thiery, Wim, et al. "Hazardous thunderstorm intensification over Lake Victoria." Nature communications vol. 7 (2016): 12786. doi: https://doi.org/10.1038/ncomms12786
Thiery W, Davin EL, Seneviratne SI, Bedka K, Lhermitte S, van Lipzig NP. Hazardous thunderstorm intensification over Lake Victoria. Nat Commun. 2016 Sep 23;7:12786. doi: 10.1038/ncomms12786. PMID: 27658848; PMCID: PMC5036145.
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Global hunger and climate change adaptation through international trade.

Nature climate change

Janssens C, Havlík P, Krisztin T, Baker J, Frank S, Hasegawa T, Leclère D, Ohrel S, Ragnauth S, Schmid E, Valin H, Van Lipzig N, Maertens M.
PMID: 33564324
Nat Clim Chang. 2020 Jul 20;10:829-835. doi: 10.1038/s41558-020-0847-4.

International trade enables us to exploit regional differences in climate change impacts and is increasingly regarded as a potential adaptation mechanism. Here, we focus on hunger reduction through international trade under alternative trade scenarios for a wide range of...

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Janssens C, Havlík P, Krisztin T, et al. Global hunger and climate change adaptation through international trade. Nat Clim Chang. 2020;10:829-835doi: 10.1038/s41558-020-0847-4.
Janssens, C., Havlík, P., Krisztin, T., Baker, J., Frank, S., Hasegawa, T., Leclère, D., Ohrel, S., Ragnauth, S., Schmid, E., Valin, H., Van Lipzig, N., & Maertens, M. (2020). Global hunger and climate change adaptation through international trade. Nature climate change, 10829-835. https://doi.org/10.1038/s41558-020-0847-4
Janssens, Charlotte, et al. "Global hunger and climate change adaptation through international trade." Nature climate change vol. 10 (2020): 829-835. doi: https://doi.org/10.1038/s41558-020-0847-4
Janssens C, Havlík P, Krisztin T, Baker J, Frank S, Hasegawa T, Leclère D, Ohrel S, Ragnauth S, Schmid E, Valin H, Van Lipzig N, Maertens M. Global hunger and climate change adaptation through international trade. Nat Clim Chang. 2020 Jul 20;10:829-835. doi: 10.1038/s41558-020-0847-4. PMID: 33564324; PMCID: PMC7869491.
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A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges.

Reviews of geophysics (Washington, D.C. : 1985)

Prein AF, Langhans W, Fosser G, Ferrone A, Ban N, Goergen K, Keller M, Tölle M, Gutjahr O, Feser F, Brisson E, Kollet S, Schmidli J, van Lipzig NP, Leung R.
PMID: 27478878
Rev Geophys. 2015 Jun;53(2):323-361. doi: 10.1002/2014RG000475. Epub 2015 May 27.

Regional climate modeling using convection-permitting models (CPMs; horizontal grid spacing 10 km). CPMs no longer rely on convection parameterization schemes, which had been identified as a major source of errors and uncertainties in LSMs. Moreover, CPMs allow for a...

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Prein AF, Langhans W, Fosser G, et al. A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges. Rev Geophys. 2015;53(2):323-361doi: 10.1002/2014RG000475.
Prein, A. F., Langhans, W., Fosser, G., Ferrone, A., Ban, N., Goergen, K., Keller, M., Tölle, M., Gutjahr, O., Feser, F., Brisson, E., Kollet, S., Schmidli, J., van Lipzig, N. P., & Leung, R. (2015). A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges. Reviews of geophysics (Washington, D.C. : 1985), 53(2), 323-361. https://doi.org/10.1002/2014RG000475
Prein, Andreas F, et al. "A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges." Reviews of geophysics (Washington, D.C. : 1985) vol. 53,2 (2015): 323-361. doi: https://doi.org/10.1002/2014RG000475
Prein AF, Langhans W, Fosser G, Ferrone A, Ban N, Goergen K, Keller M, Tölle M, Gutjahr O, Feser F, Brisson E, Kollet S, Schmidli J, van Lipzig NP, Leung R. A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges. Rev Geophys. 2015 Jun;53(2):323-361. doi: 10.1002/2014RG000475. Epub 2015 May 27. PMID: 27478878; PMCID: PMC4949718.
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Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184].

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Notenboom S, Weigand KM, Proost JH, van Lipzig MM, van de Steeg E, van den Broek PHH, Greupink R, Russel FGM, Groothuis GMM.
PMID: 29650218
Eur J Pharm Sci. 2018 May 30;117:392-393. doi: 10.1016/j.ejps.2018.04.005.

No abstract available.

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Notenboom S, Weigand KM, Proost JH, et al. Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184]. Eur J Pharm Sci. 2018;117:392-393doi: 10.1016/j.ejps.2018.04.005.
Notenboom, S., Weigand, K. M., Proost, J. H., van Lipzig, M. M., van de Steeg, E., van den Broek, P. H. H., Greupink, R., Russel, F. G. M., & Groothuis, G. M. M. (2018). Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184]. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 117392-393. https://doi.org/10.1016/j.ejps.2018.04.005
Notenboom, Sylvia, et al. "Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184]." European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences vol. 117 (2018): 392-393. doi: https://doi.org/10.1016/j.ejps.2018.04.005
Notenboom S, Weigand KM, Proost JH, van Lipzig MM, van de Steeg E, van den Broek PHH, Greupink R, Russel FGM, Groothuis GMM. Corrigendum to 'Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs' [European Journal of Pharmaceutical Sciences 115 (2018) 175-184]. Eur J Pharm Sci. 2018 May 30;117:392-393. doi: 10.1016/j.ejps.2018.04.005. PMID: 29650218.
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