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Showing 1 to 12 of 64 entries
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Progranulin Levels in Plasma and Cerebrospinal Fluid in Granulin Mutation Carriers.

Dementia and geriatric cognitive disorders extra

Meeter LH, Patzke H, Loewen G, Dopper EG, Pijnenburg YA, van Minkelen R, van Swieten JC.
PMID: 27703466
Dement Geriatr Cogn Dis Extra. 2016 Jul 22;6(2):330-340. doi: 10.1159/000447738. eCollection 2016.

BACKGROUND: Pathogenic mutations in the granulin gene METHODS: Fluctuations in plasma PGRN (n = 41) and its relationship with cerebrospinal fluid (CSF, n = 32) and specific single nucleotide polymorphisms were investigated in pre- and symptomatic RESULTS: Plasma PGRN...

Poly(GP), neurofilament and grey matter deficits in .

Annals of clinical and translational neurology

Meeter LHH, Gendron TF, Sias AC, Jiskoot LC, Russo SP, Donker Kaat L, Papma JM, Panman JL, van der Ende EL, Dopper EG, Franzen S, Graff C, Boxer AL, Rosen HJ, Sanchez-Valle R, Galimberti D, Pijnenburg YAL, Benussi L, Ghidoni R, Borroni B, Laforce R, Del Campo M, Teunissen CE, van Minkelen R, Rojas JC, Coppola G, Geschwind DH, Rademakers R, Karydas AM, Öijerstedt L, Scarpini E, Binetti G, Padovani A, Cash DM, Dick KM, Bocchetta M, Miller BL, Rohrer JD, Petrucelli L, van Swieten JC, Lee SE.
PMID: 29761121
Ann Clin Transl Neurol. 2018 Apr 06;5(5):583-597. doi: 10.1002/acn3.559. eCollection 2018 May.

OBJECTIVE: To evaluate poly(GP), a dipeptide repeat protein, and neurofilament light chain (NfL) as biomarkers in presymptomatic METHODS: We measured poly(GP) and NfL levels in cerebrospinal fluid (CSF) from 25 presymptomatic RESULTS: Poly(GP) was present in INTERPRETATION: This study...

ICA-based artifact removal diminishes scan site differences in multi-center resting-state fMRI.

Frontiers in neuroscience

Feis RA, Smith SM, Filippini N, Douaud G, Dopper EG, Heise V, Trachtenberg AJ, van Swieten JC, van Buchem MA, Rombouts SA, Mackay CE.
PMID: 26578859
Front Neurosci. 2015 Oct 27;9:395. doi: 10.3389/fnins.2015.00395. eCollection 2015.

Resting-state fMRI (R-fMRI) has shown considerable promise in providing potential biomarkers for diagnosis, prognosis and drug response across a range of diseases. Incorporating R-fMRI into multi-center studies is becoming increasingly popular, imposing technical challenges on data acquisition and analysis,...

Novel CSF biomarkers to discriminate FTLD and its pathological subtypes.

Annals of clinical and translational neurology

Del Campo M, Galimberti D, Elias N, Boonkamp L, Pijnenburg YA, van Swieten JC, Watts K, Paciotti S, Beccari T, Hu W, Teunissen CE.
PMID: 30349851
Ann Clin Transl Neurol. 2018 Sep 07;5(10):1163-1175. doi: 10.1002/acn3.629. eCollection 2018 Oct.

OBJECTIVE: Frontotemporal lobar degeneration (FTLD) is the second most prevalent dementia in young patients and is characterized by the presence of two main protein aggregates in the brain, tau (FTLD-Tau) or TDP43 (FTLD-TDP), which likely require distinct pharmacological therapy....

Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI.

NeuroImage. Clinical

Feis RA, Bouts MJRJ, Panman JL, Jiskoot LC, Dopper EGP, Schouten TM, de Vos F, van der Grond J, van Swieten JC, Rombouts SARB.
PMID: 30827922
Neuroimage Clin. 2019;22:101718. doi: 10.1016/j.nicl.2019.101718. Epub 2019 Mar 01.

BACKGROUND: Classification models based on magnetic resonance imaging (MRI) may aid early diagnosis of frontotemporal dementia (FTD) but have only been applied in established FTD cases. Detection of FTD patients in earlier disease stages, such as presymptomatic mutation carriers,...

Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study.

Alzheimer's & dementia (Amsterdam, Netherlands)

Poos JM, Russell LL, Peakman G, Bocchetta M, Greaves CV, Jiskoot LC, van der Ende EL, Seelaar H, Papma JM, van den Berg E, Pijnenburg YAL, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Graff C, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia C, Finger E, Vandenberghe R, de Medonça A, Tagliavini F, Butler CR, Santana I, Ber IL, Gerhard A, Ducharme S, Levin J, Danek A, Otto M, Sorbi S, Pasquier F, van Swieten JC, Rohrer JD.
PMID: 34027016
Alzheimers Dement (Amst). 2021 May 13;13(1):e12185. doi: 10.1002/dad2.12185. eCollection 2021.

INTRODUCTION: We aimed to assess episodic memory in genetic frontotemporal dementia (FTD) with the Free and Cued Selective Reminding Test (FCSRT).METHODS: The FCSRT was administered in 417 presymptomatic and symptomatic mutation carriers (181 chromosome 9 open reading frame 72...

Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies.

Biomolecules

Campo MD, Pijnenburg YAL, Chen-Plotkin A, Irwin DJ, Grossman M, Twaalfhoven HAM, Hu WT, Meeter LH, van Swieten J, Vermunt L, Martens F, Heijboer AC, Teunissen CE.
PMID: 34680117
Biomolecules. 2021 Oct 08;11(10). doi: 10.3390/biom11101484.

Biomarkers to discriminate the main pathologies underlying frontotemporal lobar degeneration (FTLD-Tau, FTLD-TDP) are lacking. Our previous FTLD cerebrospinal fluid (CSF) proteome study revealed that sex hormone-binding globulin (SHBG) was specifically increased in FTLD-Tau patients. Here we investigated the potential...

Practice effects in genetic frontotemporal dementia and at-risk individuals: a GENFI study.

Journal of neurology, neurosurgery, and psychiatry

Öijerstedt L, Andersson C, Jelic V, van Swieten JC, Jiskoot LC, Seelaar H, Borroni B, Sanchez-Valle R, Moreno F, Laforce R, Synofzik M, Galimberti D, Rowe JB, Masellis M, Tartaglia MC, Finger E, Vandenberghe R, de Mendonca A, Tagliavini F, Santana I, Ducharme S, Butler CR, Gerhard A, Levin J, Danek A, Otto M, Frisoni G, Ghidoni R, Sorbi S, Rohrer JD, Graff C.
PMID: 34408008
J Neurol Neurosurg Psychiatry. 2021 Aug 18; doi: 10.1136/jnnp-2021-327005. Epub 2021 Aug 18.

No abstract available.

Unravelling the clinical spectrum and the role of repeat length in .

Journal of neurology, neurosurgery, and psychiatry

van der Ende EL, Jackson JL, White A, Seelaar H, van Blitterswijk M, Van Swieten JC.
PMID: 33452054
J Neurol Neurosurg Psychiatry. 2021 May;92(5):502-509. doi: 10.1136/jnnp-2020-325377. Epub 2021 Jan 15.

Since the discovery of the

Modelling the cascade of biomarker changes in .

Journal of neurology, neurosurgery, and psychiatry

Panman JL, Venkatraghavan V, van der Ende EL, Steketee RME, Jiskoot LC, Poos JM, Dopper EGP, Meeter LHH, Donker Kaat L, Rombouts SARB, Vernooij MW, Kievit AJA, Premi E, Cosseddu M, Bonomi E, Olives J, Rohrer JD, Sánchez-Valle R, Borroni B, Bron EE, Van Swieten JC, Papma JM, Klein S.
PMID: 33452053
J Neurol Neurosurg Psychiatry. 2021 May;92(5):494-501. doi: 10.1136/jnnp-2020-323541. Epub 2021 Jan 15.

OBJECTIVE: Progranulin-related frontotemporal dementia (FTD-METHODS: We included 56 presymptomatic and 35 symptomatic RESULTS: Language functioning and NfL were the earliest abnormal biomarkers in FTD-CONCLUSION: Degeneration of axons and language deficits are indicated to be the earliest biomarkers in FTD-

Trapping and Detrapping in Colloidal Perovskite Nanoplatelets: Elucidation and Prevention of Nonradiative Processes through Chemical Treatment.

The journal of physical chemistry. C, Nanomaterials and interfaces

Vonk SJW, Fridriksson MB, Hinterding SOM, Mangnus MJJ, van Swieten TP, Grozema FC, Rabouw FT, van der Stam W.
PMID: 32421082
J Phys Chem C Nanomater Interfaces. 2020 Apr 09;124(14):8047-8054. doi: 10.1021/acs.jpcc.0c02287. Epub 2020 Mar 18.

Metal-halide perovskite nanocrystals show promise as the future active material in photovoltaics, lighting, and other optoelectronic applications. The appeal of these materials is largely due to the robustness of the optoelectronic properties to structural defects. The photoluminescence quantum yield...

Left ventricular assist device as bridge to transplantation in patients with end-stage heart failure: Eight-year experience with the implantable HeartMate LVAS.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Lahpor JR, de Jonge N, van Swieten HA, Wesenhagen H, Klöpping C, Geertman JH, Oosterom A, Rodermans B, Kirkels JH.
PMID: 25696107
Neth Heart J. 2002 Jun;10(6):267-271.

OBJECTIVE: To evaluate the use of left ventricular assist devices (LVAD) as bridge to heart transplantation (HTx) in patients with end-stage heart failure.METHOD: Between March 1993 and December 2001, 38 patients with refractory end-stage heart failure underwent HeartMate LVAD...

Showing 1 to 12 of 64 entries