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Showing 1 to 12 of 171 entries
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Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population.

The Journal of frailty & aging

Aarts S, Patel KV, Garcia ME, Van den Akker M, Verhey FR, Metsemakers JF, Van Boxtel MP, Gudnason V, Jonsdottir MK, Siggeirsdottir K, Jonsson PV, Harris TB, Launer LJ.
PMID: 27030941
J Frailty Aging. 2015;4(3):131-8. doi: 10.14283/jfa.2015.45.

BACKGROUND: Frailty is often associated with multimorbidity and disability.OBJECTIVES: We investigated heterogeneity in the frail older population by characterizing five subpopulations according to quantitative biological markers, multimorbidity and disability, and examined their association with mortality and nursing home admission.DESIGN:...

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Aarts S, Patel KV, Garcia ME, et al. Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population. J Frailty Aging. 2015;4(3):131-8doi: 10.14283/jfa.2015.45.
Aarts, S., Patel, K. V., Garcia, M. E., Van den Akker, M., Verhey, F. R., Metsemakers, J. F., Van Boxtel, M. P., Gudnason, V., Jonsdottir, M. K., Siggeirsdottir, K., Jonsson, P. V., Harris, T. B., & Launer, L. J. (2015). Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population. The Journal of frailty & aging, 4(3), 131-8. https://doi.org/10.14283/jfa.2015.45
Aarts, S, et al. "Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population." The Journal of frailty & aging vol. 4,3 (2015): 131-8. doi: https://doi.org/10.14283/jfa.2015.45
Aarts S, Patel KV, Garcia ME, Van den Akker M, Verhey FR, Metsemakers JF, Van Boxtel MP, Gudnason V, Jonsdottir MK, Siggeirsdottir K, Jonsson PV, Harris TB, Launer LJ. Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population. J Frailty Aging. 2015;4(3):131-8. doi: 10.14283/jfa.2015.45. PMID: 27030941; PMCID: PMC5367922.
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Global surgery and the dilemma for obstetricians.

Lancet (London, England)

Rijken MJ, Meguid T, van den Akker T, van Roosmalen J, Stekelenburg J.
PMID: 26841745
Lancet. 2015 Nov 14;386(10007):1941-1942. doi: 10.1016/S0140-6736(15)00828-4. Epub 2015 Nov 13.

No abstract available.

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Rijken MJ, Meguid T, van den Akker T, et al. Global surgery and the dilemma for obstetricians. Lancet. 2015;386(10007):1941-1942doi: 10.1016/S0140-6736(15)00828-4.
Rijken, M. J., Meguid, T., van den Akker, T., van Roosmalen, J., Stekelenburg, J. (2015). Global surgery and the dilemma for obstetricians. Lancet (London, England), 386(10007), 1941-1942. https://doi.org/10.1016/S0140-6736(15)00828-4
Rijken, Marcus J, et al. "Global surgery and the dilemma for obstetricians." Lancet (London, England) vol. 386,10007 (2015): 1941-1942. doi: https://doi.org/10.1016/S0140-6736(15)00828-4
Rijken MJ, Meguid T, van den Akker T, van Roosmalen J, Stekelenburg J. Global surgery and the dilemma for obstetricians. Lancet. 2015 Nov 14;386(10007):1941-1942. doi: 10.1016/S0140-6736(15)00828-4. Epub 2015 Nov 13. PMID: 26841745.
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Gene analysis for longitudinal family data using random-effects models.

BMC proceedings

Houwing-Duistermaat JJ, Helmer Q, Balliu B, van den Akker E, Tsonaka R, Uh HW.
PMID: 25519415
BMC Proc. 2014 Jun 17;8:S88. doi: 10.1186/1753-6561-8-S1-S88. eCollection 2014.

We have extended our recently developed 2-step approach for gene-based analysis to the family design and to the analysis of rare variants. The goal of this approach is to study the joint effect of multiple single-nucleotide polymorphisms that belong...

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Houwing-Duistermaat JJ, Helmer Q, Balliu B, et al. Gene analysis for longitudinal family data using random-effects models. BMC Proc. 2014;8:S88doi: 10.1186/1753-6561-8-S1-S88.
Houwing-Duistermaat, J. J., Helmer, Q., Balliu, B., van den Akker, E., Tsonaka, R., & Uh, H. W. (2014). Gene analysis for longitudinal family data using random-effects models. BMC proceedings, 8S88. https://doi.org/10.1186/1753-6561-8-S1-S88
Houwing-Duistermaat, Jeanine J, et al. "Gene analysis for longitudinal family data using random-effects models." BMC proceedings vol. 8 (2014): S88. doi: https://doi.org/10.1186/1753-6561-8-S1-S88
Houwing-Duistermaat JJ, Helmer Q, Balliu B, van den Akker E, Tsonaka R, Uh HW. Gene analysis for longitudinal family data using random-effects models. BMC Proc. 2014 Jun 17;8:S88. doi: 10.1186/1753-6561-8-S1-S88. eCollection 2014. PMID: 25519415; PMCID: PMC4143685.
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Functions and responsibilities of organizations dealing with surrogate motherhood in the UK.

Human fertility (Cambridge, England)

van Den Akker OB.
PMID: 11844301
Hum Fertil (Camb). 1998;1(1):10-13.

The separation of maternity from social motherhood and progress in reproductive technology raise many social, psychological, medical and legal issues (van den Akker, 1994). The most recent British Medical Association report (BMA, 1996) acknowledged the practice of surrogacy and...

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van Den Akker OB. Functions and responsibilities of organizations dealing with surrogate motherhood in the UK. Hum Fertil (Camb). 1998;1(1):10-13
van Den Akker, O. B. (1998). Functions and responsibilities of organizations dealing with surrogate motherhood in the UK. Human fertility (Cambridge, England), 1(1), 10-13.
van Den Akker, Olga B. A.. "Functions and responsibilities of organizations dealing with surrogate motherhood in the UK." Human fertility (Cambridge, England) vol. 1,1 (1998): 10-13.
van Den Akker OB. Functions and responsibilities of organizations dealing with surrogate motherhood in the UK. Hum Fertil (Camb). 1998;1(1):10-13. PMID: 11844301.
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Multimorbidity's many challenges.

BMJ (Clinical research ed.)

Fortin M, Soubhi H, Hudon C, Bayliss EA, van den Akker M.
PMID: 17510108
BMJ. 2007 May 19;334(7602):1016-7. doi: 10.1136/bmj.39201.463819.2C.

No abstract available.

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Fortin M, Soubhi H, Hudon C, et al. Multimorbidity's many challenges. BMJ. 2007;334(7602):1016-7doi: 10.1136/bmj.39201.463819.2C.
Fortin, M., Soubhi, H., Hudon, C., Bayliss, E. A., & van den Akker, M. (2007). Multimorbidity's many challenges. BMJ (Clinical research ed.), 334(7602), 1016-7. https://doi.org/10.1136/bmj.39201.463819.2C
Fortin, Martin, et al. "Multimorbidity's many challenges." BMJ (Clinical research ed.) vol. 334,7602 (2007): 1016-7. doi: https://doi.org/10.1136/bmj.39201.463819.2C
Fortin M, Soubhi H, Hudon C, Bayliss EA, van den Akker M. Multimorbidity's many challenges. BMJ. 2007 May 19;334(7602):1016-7. doi: 10.1136/bmj.39201.463819.2C. PMID: 17510108; PMCID: PMC1871747.
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Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment.

International journal of endocrinology and metabolism

van der Kaay D, van den Akker E.
PMID: 25237318
Int J Endocrinol Metab. 2014 Jul 01;12(3):e14657. doi: 10.5812/ijem.14657. eCollection 2014 Jul.

INTRODUCTION: Nonclassical congenital adrenal hyperplasia (CAH) is characterized by sufficient cortisol and aldosterone production at the cost of androgen overproduction. Hydrocortisone or dexamethasone in supraphysiological doses are current treatment; however, their downside is suppression of endogenous cortisol production resulting...

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van der Kaay D, van den Akker E. Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment. Int J Endocrinol Metab. 2014;12(3):e14657doi: 10.5812/ijem.14657.
van der Kaay, D., & van den Akker, E. (2014). Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment. International journal of endocrinology and metabolism, 12(3), e14657. https://doi.org/10.5812/ijem.14657
van der Kaay, Danielle, and van den Akker, Erica. "Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment." International journal of endocrinology and metabolism vol. 12,3 (2014): e14657. doi: https://doi.org/10.5812/ijem.14657
van der Kaay D, van den Akker E. Ultralow-dose Dexamethasone to Preserve Endogenous Cortisol Stress Response in Nonclassical Congenital Adrenal Hyperplasia: A New Promising Treatment. Int J Endocrinol Metab. 2014 Jul 01;12(3):e14657. doi: 10.5812/ijem.14657. eCollection 2014 Jul. PMID: 25237318; PMCID: PMC4166204.
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Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi.

International health

van den Akker T, Radge G, Mateyu A, Mwagomba B, Bemelmans M, Reid T.
PMID: 24038052
Int Health. 2011 Mar;3(1):66-8. doi: 10.1016/j.inhe.2010.11.001.

Attendance for intrapartum care in Thyolo District, Malawi, was studied following implementation of a locally valued, non-monetary incentive. The number of facility-based deliveries per month was compared between the fourth quarter of 2007 and the third quarter of 2009,...

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van den Akker T, Radge G, Mateyu A, et al. Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. Int Health. 2011;3(1):66-8doi: 10.1016/j.inhe.2010.11.001.
van den Akker, T., Radge, G., Mateyu, A., Mwagomba, B., Bemelmans, M., & Reid, T. (2011). Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. International health, 3(1), 66-8. https://doi.org/10.1016/j.inhe.2010.11.001
van den Akker, Thomas, et al. "Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi." International health vol. 3,1 (2011): 66-8. doi: https://doi.org/10.1016/j.inhe.2010.11.001
van den Akker T, Radge G, Mateyu A, Mwagomba B, Bemelmans M, Reid T. Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. Int Health. 2011 Mar;3(1):66-8. doi: 10.1016/j.inhe.2010.11.001. PMID: 24038052.
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Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium.

Journal of comorbidity

van Merode T, van de Ven K, van den Akker M.
PMID: 29651408
J Comorb. 2018 Mar 08;8(1):9-15. doi: 10.15256/joc.2018.8.119. eCollection 2018.

BACKGROUND: Physicians and other healthcare professionals involved in the care of patients with multimorbidity should consider the problems these patients experience in managing their own conditions. However, treatment burden from the patient's perspective has been poorly explored, even though...

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van Merode T, van de Ven K, van den Akker M. Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium. J Comorb. 2018;8(1):9-15doi: 10.15256/joc.2018.8.119.
van Merode, T., van de Ven, K., & van den Akker, M. (2018). Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium. Journal of comorbidity, 8(1), 9-15. https://doi.org/10.15256/joc.2018.8.119
van Merode, Tiny, et al. "Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium." Journal of comorbidity vol. 8,1 (2018): 9-15. doi: https://doi.org/10.15256/joc.2018.8.119
van Merode T, van de Ven K, van den Akker M. Patients with multimorbidity and their treatment burden in different daily life domains: a qualitative study in primary care in the Netherlands and Belgium. J Comorb. 2018 Mar 08;8(1):9-15. doi: 10.15256/joc.2018.8.119. eCollection 2018. PMID: 29651408; PMCID: PMC5885066.
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Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis.

Surgery journal (New York, N.Y.)

Huizing E, Vos CG, Hulsebos RG, van den Akker PJ, Borst GJ, Ünlü Ç.
PMID: 29915809
Surg J (N Y). 2018 Jun 15;4(2):e96-e101. doi: 10.1055/s-0038-1655757. eCollection 2018 Apr.

No abstract available.

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Huizing E, Vos CG, Hulsebos RG, et al. Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis. Surg J (N Y). 2018;4(2):e96-e101doi: 10.1055/s-0038-1655757.
Huizing, E., Vos, C. G., Hulsebos, R. G., van den Akker, P. J., Borst, G. J., & Ünlü, �. �. (2018). Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis. Surgery journal (New York, N.Y.), 4(2), e96-e101. https://doi.org/10.1055/s-0038-1655757
Huizing, Eline, et al. "Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis." Surgery journal (New York, N.Y.) vol. 4,2 (2018): e96-e101. doi: https://doi.org/10.1055/s-0038-1655757
Huizing E, Vos CG, Hulsebos RG, van den Akker PJ, Borst GJ, Ünlü Ç. Patch Angioplasty or Primary Closure Following Carotid Endarterectomy for Symptomatic Carotid Artery Stenosis. Surg J (N Y). 2018 Jun 15;4(2):e96-e101. doi: 10.1055/s-0038-1655757. eCollection 2018 Apr. PMID: 29915809; PMCID: PMC6003887.
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A Validation of the French Version of the Attitudes to Aging Questionnaire (AAQ): Factor Structure, Reliability and Validity.

Psychologica Belgica

Marquet M, Missotten P, Schroyen S, van Sambeek I, van den Akker M, Van Den Broeke C, Buntinx F, Adam S.
PMID: 30479430
Psychol Belg. 2016 Mar 22;56(2):80-100. doi: 10.5334/pb.301.

No abstract available.

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Marquet M, Missotten P, Schroyen S, et al. A Validation of the French Version of the Attitudes to Aging Questionnaire (AAQ): Factor Structure, Reliability and Validity. Psychol Belg. 2016;56(2):80-100doi: 10.5334/pb.301.
Marquet, M., Missotten, P., Schroyen, S., van Sambeek, I., van den Akker, M., Van Den Broeke, C., Buntinx, F., & Adam, S. (2016). A Validation of the French Version of the Attitudes to Aging Questionnaire (AAQ): Factor Structure, Reliability and Validity. Psychologica Belgica, 56(2), 80-100. https://doi.org/10.5334/pb.301
Marquet, Manon, et al. "A Validation of the French Version of the Attitudes to Aging Questionnaire (AAQ): Factor Structure, Reliability and Validity." Psychologica Belgica vol. 56,2 (2016): 80-100. doi: https://doi.org/10.5334/pb.301
Marquet M, Missotten P, Schroyen S, van Sambeek I, van den Akker M, Van Den Broeke C, Buntinx F, Adam S. A Validation of the French Version of the Attitudes to Aging Questionnaire (AAQ): Factor Structure, Reliability and Validity. Psychol Belg. 2016 Mar 22;56(2):80-100. doi: 10.5334/pb.301. PMID: 30479430; PMCID: PMC5854168.
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Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma.

Oncogenesis

de Jong Y, Monderer D, Brandinelli E, Monchanin M, van den Akker BE, van Oosterwijk JG, Blay JY, Dutour A, Bovée JVMG.
PMID: 30242253
Oncogenesis. 2018 Sep 21;7(9):74. doi: 10.1038/s41389-018-0084-0.

Chondrosarcomas are malignant cartilage tumors showing relative resistance to conventional chemo- and radiotherapy. Previous studies showed that chondrosarcoma cells could be sensitized to chemotherapy by inhibiting the Bcl-2 family members Bcl-2, Bcl-xl and Bcl-w using ABT-737. In this study...

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de Jong Y, Monderer D, Brandinelli E, et al. Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma. Oncogenesis. 2018;7(9):74doi: 10.1038/s41389-018-0084-0.
de Jong, Y., Monderer, D., Brandinelli, E., Monchanin, M., van den Akker, B. E., van Oosterwijk, J. G., Blay, J. Y., Dutour, A., & Bovée, J. V. M. G. (2018). Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma. Oncogenesis, 7(9), 74. https://doi.org/10.1038/s41389-018-0084-0
de Jong, Yvonne, et al. "Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma." Oncogenesis vol. 7,9 (2018): 74. doi: https://doi.org/10.1038/s41389-018-0084-0
de Jong Y, Monderer D, Brandinelli E, Monchanin M, van den Akker BE, van Oosterwijk JG, Blay JY, Dutour A, Bovée JVMG. Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma. Oncogenesis. 2018 Sep 21;7(9):74. doi: 10.1038/s41389-018-0084-0. PMID: 30242253; PMCID: PMC6155044.
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Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection.

Journal of hematopathology

Khan F, van den Akker T, Hussein S, Marcellino BK, Khattar P, Glicksberg BS, Nadkarni GN, Firpo-Betancourt A, El Jamal SM.
PMID: 32837599
J Hematop. 2020 Jul 02;1-3. doi: 10.1007/s12308-020-00405-9. Epub 2020 Jul 02.

No abstract available.

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Khan F, van den Akker T, Hussein S, et al. Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection. J Hematop. 2020;1-3doi: 10.1007/s12308-020-00405-9.
Khan, F., van den Akker, T., Hussein, S., Marcellino, B. K., Khattar, P., Glicksberg, B. S., Nadkarni, G. N., Firpo-Betancourt, A., & El Jamal, S. M. (2020). Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection. Journal of hematopathology, 1-3. https://doi.org/10.1007/s12308-020-00405-9
Khan, Fahad, et al. "Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection." Journal of hematopathology vol. (2020): 1-3. doi: https://doi.org/10.1007/s12308-020-00405-9
Khan F, van den Akker T, Hussein S, Marcellino BK, Khattar P, Glicksberg BS, Nadkarni GN, Firpo-Betancourt A, El Jamal SM. Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection. J Hematop. 2020 Jul 02;1-3. doi: 10.1007/s12308-020-00405-9. Epub 2020 Jul 02. PMID: 32837599; PMCID: PMC7332243.
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Showing 1 to 12 of 171 entries