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Showing 1 to 12 of 15 entries
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Copeptin: Limited Usefulness in Early Stroke Differentiation?.

Stroke research and treatment

von Recum J, Searle J, Slagman A, Vollert JO, Endres M, Möckel M, Ebinger M.
PMID: 26167332
Stroke Res Treat. 2015;2015:768401. doi: 10.1155/2015/768401. Epub 2015 Jun 08.

Background. Stroke can be a challenging diagnosis in an emergency-setting. We sought to determine whether copeptin may be a useful biomarker to differentiate between ischemic stroke (IS), transient ischemic attack (TIA), and stroke-mimics. Methods. In patients with suspected stroke...

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von Recum J, Searle J, Slagman A, et al. Copeptin: Limited Usefulness in Early Stroke Differentiation?. Stroke Res Treat. 2015;2015:768401doi: 10.1155/2015/768401.
von Recum, J., Searle, J., Slagman, A., Vollert, J. O., Endres, M., Möckel, M., & Ebinger, M. (2015). Copeptin: Limited Usefulness in Early Stroke Differentiation?. Stroke research and treatment, 2015768401. https://doi.org/10.1155/2015/768401
von Recum, Johannes, et al. "Copeptin: Limited Usefulness in Early Stroke Differentiation?." Stroke research and treatment vol. 2015 (2015): 768401. doi: https://doi.org/10.1155/2015/768401
von Recum J, Searle J, Slagman A, Vollert JO, Endres M, Möckel M, Ebinger M. Copeptin: Limited Usefulness in Early Stroke Differentiation?. Stroke Res Treat. 2015;2015:768401. doi: 10.1155/2015/768401. Epub 2015 Jun 08. PMID: 26167332; PMCID: PMC4475751.
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Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections .

ACS infectious diseases

Cyphert EL, Zhang N, Learn GD, Hernandez CJ, von Recum HA.
PMID: 34761915
ACS Infect Dis. 2021 Dec 10;7(12):3125-3160. doi: 10.1021/acsinfecdis.1c00465. Epub 2021 Nov 11.

While orthopedic implant-associated infections are rare, revision surgeries resulting from infections incur considerable healthcare costs and represent a substantial research area clinically, in academia, and in industry. In recent years, there have been numerous advances in the development of...

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Cyphert EL, Zhang N, Learn GD, et al. Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections . ACS Infect Dis. 2021;7(12):3125-3160doi: 10.1021/acsinfecdis.1c00465.
Cyphert, E. L., Zhang, N., Learn, G. D., Hernandez, C. J., & von Recum, H. A. (2021). Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections . ACS infectious diseases, 7(12), 3125-3160. https://doi.org/10.1021/acsinfecdis.1c00465
Cyphert, Erika L, et al. "Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections ." ACS infectious diseases vol. 7,12 (2021): 3125-3160. doi: https://doi.org/10.1021/acsinfecdis.1c00465
Cyphert EL, Zhang N, Learn GD, Hernandez CJ, von Recum HA. Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections . ACS Infect Dis. 2021 Dec 10;7(12):3125-3160. doi: 10.1021/acsinfecdis.1c00465. Epub 2021 Nov 11. PMID: 34761915.
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Elucidating the Structure-Function Relationship of Solvent and Cross-Linker on Affinity-Based Release from Cyclodextrin Hydrogels.

Gels (Basel, Switzerland)

Zuckerman ST, Rivera-Delgado E, Haley RM, Korley JN, von Recum HA.
PMID: 32235748
Gels. 2020 Mar 22;6(1). doi: 10.3390/gels6010009.

Minocycline (MNC) is a tetracycline antibiotic capable of associating with cyclodextrin (CD), and it is a frontline drug for many instances of implant infection. Due to its broad-spectrum activity and long half-life, MNC represents an ideal drug for localized...

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Zuckerman ST, Rivera-Delgado E, Haley RM, et al. Elucidating the Structure-Function Relationship of Solvent and Cross-Linker on Affinity-Based Release from Cyclodextrin Hydrogels. Gels. 2020;6(1)doi: 10.3390/gels6010009.
Zuckerman, S. T., Rivera-Delgado, E., Haley, R. M., Korley, J. N., & von Recum, H. A. (2020). Elucidating the Structure-Function Relationship of Solvent and Cross-Linker on Affinity-Based Release from Cyclodextrin Hydrogels. Gels (Basel, Switzerland), 6(1), . https://doi.org/10.3390/gels6010009
Zuckerman, Sean T, et al. "Elucidating the Structure-Function Relationship of Solvent and Cross-Linker on Affinity-Based Release from Cyclodextrin Hydrogels." Gels (Basel, Switzerland) vol. 6,1 (2020). doi: https://doi.org/10.3390/gels6010009
Zuckerman ST, Rivera-Delgado E, Haley RM, Korley JN, von Recum HA. Elucidating the Structure-Function Relationship of Solvent and Cross-Linker on Affinity-Based Release from Cyclodextrin Hydrogels. Gels. 2020 Mar 22;6(1). doi: 10.3390/gels6010009. PMID: 32235748; PMCID: PMC7151216.
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Does the Journal of Investigative Surgery serve the needs of the surgical research community today?.

Journal of investigative surgery : the official journal of the Academy of Surgical Research

von Recum AF.
PMID: 8452821
J Invest Surg. 1993 Jan-Feb;6(1):1-8.

No abstract available.

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von Recum AF. Does the Journal of Investigative Surgery serve the needs of the surgical research community today?. J Invest Surg. 1993;6(1):1-8
von Recum, A. F. (1993). Does the Journal of Investigative Surgery serve the needs of the surgical research community today?. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 6(1), 1-8.
von Recum, A F. "Does the Journal of Investigative Surgery serve the needs of the surgical research community today?." Journal of investigative surgery : the official journal of the Academy of Surgical Research vol. 6,1 (1993): 1-8.
von Recum AF. Does the Journal of Investigative Surgery serve the needs of the surgical research community today?. J Invest Surg. 1993 Jan-Feb;6(1):1-8. PMID: 8452821.
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Affinity Effects on the Release of Non-Conventional Antifibrotics from Polymer Depots.

Pharmaceutics

Rohner NA, Nguyen D, von Recum HA.
PMID: 32192207
Pharmaceutics. 2020 Mar 17;12(3). doi: 10.3390/pharmaceutics12030275.

For many chronic fibrotic conditions, there is a need for local, sustained antifibrotic drug delivery. A recent trend in the pharmaceutical industry is the repurposing of approved drugs. This paper investigates drugs that are classically used for anthelmintic activity...

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Rohner NA, Nguyen D, von Recum HA. Affinity Effects on the Release of Non-Conventional Antifibrotics from Polymer Depots. Pharmaceutics. 2020;12(3)doi: 10.3390/pharmaceutics12030275.
Rohner, N. A., Nguyen, D., & von Recum, H. A. (2020). Affinity Effects on the Release of Non-Conventional Antifibrotics from Polymer Depots. Pharmaceutics, 12(3), . https://doi.org/10.3390/pharmaceutics12030275
Rohner, Nathan A, et al. "Affinity Effects on the Release of Non-Conventional Antifibrotics from Polymer Depots." Pharmaceutics vol. 12,3 (2020). doi: https://doi.org/10.3390/pharmaceutics12030275
Rohner NA, Nguyen D, von Recum HA. Affinity Effects on the Release of Non-Conventional Antifibrotics from Polymer Depots. Pharmaceutics. 2020 Mar 17;12(3). doi: 10.3390/pharmaceutics12030275. PMID: 32192207; PMCID: PMC7151100.
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Two-Stage Revision Anterior Cruciate Ligament Reconstruction Using Silicate-Substituted Calcium Phosphate.

Arthroscopy techniques

Schnetzke M, Vetter S, Linden PV, Grützner PA, von Recum J.
PMID: 32042579
Arthrosc Tech. 2019 Sep 26;8(10):e1239-e1246. doi: 10.1016/j.eats.2019.06.015. eCollection 2019 Oct.

Revision surgery after failed primary anterior cruciate ligament reconstruction is technically demanding. In cases in which the tunnels of the primary anterior cruciate ligament reconstruction are widened to greater than 10 mm and/or are incorrectly positioned, a 2-stage procedure...

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Schnetzke M, Vetter S, Linden PV, et al. Two-Stage Revision Anterior Cruciate Ligament Reconstruction Using Silicate-Substituted Calcium Phosphate. Arthrosc Tech. 2019;8(10):e1239-e1246doi: 10.1016/j.eats.2019.06.015.
Schnetzke, M., Vetter, S., Linden, P. V., Grützner, P. A., & von Recum, J. (2019). Two-Stage Revision Anterior Cruciate Ligament Reconstruction Using Silicate-Substituted Calcium Phosphate. Arthroscopy techniques, 8(10), e1239-e1246. https://doi.org/10.1016/j.eats.2019.06.015
Schnetzke, Marc, et al. "Two-Stage Revision Anterior Cruciate Ligament Reconstruction Using Silicate-Substituted Calcium Phosphate." Arthroscopy techniques vol. 8,10 (2019): e1239-e1246. doi: https://doi.org/10.1016/j.eats.2019.06.015
Schnetzke M, Vetter S, Linden PV, Grützner PA, von Recum J. Two-Stage Revision Anterior Cruciate Ligament Reconstruction Using Silicate-Substituted Calcium Phosphate. Arthrosc Tech. 2019 Sep 26;8(10):e1239-e1246. doi: 10.1016/j.eats.2019.06.015. eCollection 2019 Oct. PMID: 32042579; PMCID: PMC7000346.
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Thermomechanical Properties, Antibiotic Release, and Bioactivity of a Sterilized Cyclodextrin Drug Delivery System.

Journal of materials chemistry. B

Halpern JM, Gormley CA, Keech M, von Recum HA.
PMID: 24949201
J Mater Chem B. 2014 May 14;2(18):2764-2772. doi: 10.1039/C4TB00083H.

Various local drug delivery devices and coatings are being developed as slow, sustained release mechanism for drugs, yet the polymers are typically not evaluated after commercial sterilization techniques. We examine the effect that commercial sterilization techniques have on the...

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Halpern JM, Gormley CA, Keech M, et al. Thermomechanical Properties, Antibiotic Release, and Bioactivity of a Sterilized Cyclodextrin Drug Delivery System. J Mater Chem B. 2014;2(18):2764-2772doi: 10.1039/C4TB00083H.
Halpern, J. M., Gormley, C. A., Keech, M., & von Recum, H. A. (2014). Thermomechanical Properties, Antibiotic Release, and Bioactivity of a Sterilized Cyclodextrin Drug Delivery System. Journal of materials chemistry. B, 2(18), 2764-2772. https://doi.org/10.1039/C4TB00083H
Halpern, Jeffrey M, et al. "Thermomechanical Properties, Antibiotic Release, and Bioactivity of a Sterilized Cyclodextrin Drug Delivery System." Journal of materials chemistry. B vol. 2,18 (2014): 2764-2772. doi: https://doi.org/10.1039/C4TB00083H
Halpern JM, Gormley CA, Keech M, von Recum HA. Thermomechanical Properties, Antibiotic Release, and Bioactivity of a Sterilized Cyclodextrin Drug Delivery System. J Mater Chem B. 2014 May 14;2(18):2764-2772. doi: 10.1039/C4TB00083H. PMID: 24949201; PMCID: PMC4058863.
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Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections .

ACS infectious diseases

Cyphert EL, Zhang N, Learn GD, Hernandez CJ, von Recum HA.
PMID: 34761915
ACS Infect Dis. 2021 Dec 10;7(12):3125-3160. doi: 10.1021/acsinfecdis.1c00465. Epub 2021 Nov 11.

While orthopedic implant-associated infections are rare, revision surgeries resulting from infections incur considerable healthcare costs and represent a substantial research area clinically, in academia, and in industry. In recent years, there have been numerous advances in the development of...

Cite
Cyphert EL, Zhang N, Learn GD, et al. Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections . ACS Infect Dis. 2021;7(12):3125-3160doi: 10.1021/acsinfecdis.1c00465.
Cyphert, E. L., Zhang, N., Learn, G. D., Hernandez, C. J., & von Recum, H. A. (2021). Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections . ACS infectious diseases, 7(12), 3125-3160. https://doi.org/10.1021/acsinfecdis.1c00465
Cyphert, Erika L, et al. "Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections ." ACS infectious diseases vol. 7,12 (2021): 3125-3160. doi: https://doi.org/10.1021/acsinfecdis.1c00465
Cyphert EL, Zhang N, Learn GD, Hernandez CJ, von Recum HA. Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections . ACS Infect Dis. 2021 Dec 10;7(12):3125-3160. doi: 10.1021/acsinfecdis.1c00465. Epub 2021 Nov 11. PMID: 34761915.
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Localized Affinity-Based Delivery of Prinomastat for Cancer Treatment.

ACS biomaterials science & engineering

Rivera-Delgado E, Nam JK, von Recum HA.
PMID: 33465922
ACS Biomater Sci Eng. 2017 Mar 13;3(3):238-242. doi: 10.1021/acsbiomaterials.6b00626. Epub 2017 Feb 02.

Glioblastoma multiforme patients suffer a median survival of 14 months, facilitated by the highly invasive nature of this cancer that allows for it to evade conventional therapy. Prinomastat targets the essential matrix metalloproteinase degradation of the extracellular matrix needed...

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Rivera-Delgado E, Nam JK, von Recum HA. Localized Affinity-Based Delivery of Prinomastat for Cancer Treatment. ACS Biomater Sci Eng. 2017;3(3):238-242doi: 10.1021/acsbiomaterials.6b00626.
Rivera-Delgado, E., Nam, J. K., & von Recum, H. A. (2017). Localized Affinity-Based Delivery of Prinomastat for Cancer Treatment. ACS biomaterials science & engineering, 3(3), 238-242. https://doi.org/10.1021/acsbiomaterials.6b00626
Rivera-Delgado, Edgardo, et al. "Localized Affinity-Based Delivery of Prinomastat for Cancer Treatment." ACS biomaterials science & engineering vol. 3,3 (2017): 238-242. doi: https://doi.org/10.1021/acsbiomaterials.6b00626
Rivera-Delgado E, Nam JK, von Recum HA. Localized Affinity-Based Delivery of Prinomastat for Cancer Treatment. ACS Biomater Sci Eng. 2017 Mar 13;3(3):238-242. doi: 10.1021/acsbiomaterials.6b00626. Epub 2017 Feb 02. PMID: 33465922.
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Characteristics of two different locking compression plates in the volar fixation of complex articular distal radius fractures.

Bone & joint research

von Recum J, Matschke S, Jupiter JB, Ring D, Souer JS, Huber M, Audigé L.
PMID: 23610680
Bone Joint Res. 2012 Jun 01;1(6):111-7. doi: 10.1302/2046-3758.16.2000008. Print 2012 Jun.

OBJECTIVES: To investigate the differences of open reduction and internal fixation (ORIF) of complex AO Type C distal radius fractures between two different models of a single implant type.METHODS: A total of 136 patients who received either a 2.4...

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von Recum J, Matschke S, Jupiter JB, et al. Characteristics of two different locking compression plates in the volar fixation of complex articular distal radius fractures. Bone Joint Res. 2012;1(6):111-7doi: 10.1302/2046-3758.16.2000008.
von Recum, J., Matschke, S., Jupiter, J. B., Ring, D., Souer, J. S., Huber, M., & Audigé, L. (2012). Characteristics of two different locking compression plates in the volar fixation of complex articular distal radius fractures. Bone & joint research, 1(6), 111-7. https://doi.org/10.1302/2046-3758.16.2000008
von Recum, J, et al. "Characteristics of two different locking compression plates in the volar fixation of complex articular distal radius fractures." Bone & joint research vol. 1,6 (2012): 111-7. doi: https://doi.org/10.1302/2046-3758.16.2000008
von Recum J, Matschke S, Jupiter JB, Ring D, Souer JS, Huber M, Audigé L. Characteristics of two different locking compression plates in the volar fixation of complex articular distal radius fractures. Bone Joint Res. 2012 Jun 01;1(6):111-7. doi: 10.1302/2046-3758.16.2000008. Print 2012 Jun. PMID: 23610680; PMCID: PMC3626195.
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Ultrasound Triggered Drug Release from Affinity-Based β-Cyclodextrin Polymers for Infection Control.

Annals of biomedical engineering

Bohara S, Rohner N, Budziszewski E, Suthakorn J, von Recum HA, Exner AA.
PMID: 34173088
Ann Biomed Eng. 2021 Sep;49(9):2513-2521. doi: 10.1007/s10439-021-02814-y. Epub 2021 Jun 25.

This work demonstrates a slow, sustained drug delivery system that provides on-demand delivery bursts through the application of pulsed therapeutic ultrasound (TUS). Insoluble β-cyclodextrin-polymer (pCD) disks were loaded with a saturated antibiotic solution of rifampicin (RIF) and used for...

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Bohara S, Rohner N, Budziszewski E, et al. Ultrasound Triggered Drug Release from Affinity-Based β-Cyclodextrin Polymers for Infection Control. Ann Biomed Eng. 2021;49(9):2513-2521doi: 10.1007/s10439-021-02814-y.
Bohara, S., Rohner, N., Budziszewski, E., Suthakorn, J., von Recum, H. A., & Exner, A. A. (2021). Ultrasound Triggered Drug Release from Affinity-Based β-Cyclodextrin Polymers for Infection Control. Annals of biomedical engineering, 49(9), 2513-2521. https://doi.org/10.1007/s10439-021-02814-y
Bohara, Smriti, et al. "Ultrasound Triggered Drug Release from Affinity-Based β-Cyclodextrin Polymers for Infection Control." Annals of biomedical engineering vol. 49,9 (2021): 2513-2521. doi: https://doi.org/10.1007/s10439-021-02814-y
Bohara S, Rohner N, Budziszewski E, Suthakorn J, von Recum HA, Exner AA. Ultrasound Triggered Drug Release from Affinity-Based β-Cyclodextrin Polymers for Infection Control. Ann Biomed Eng. 2021 Sep;49(9):2513-2521. doi: 10.1007/s10439-021-02814-y. Epub 2021 Jun 25. PMID: 34173088; PMCID: PMC8458245.
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Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery.

Antibiotics (Basel, Switzerland)

Cyphert EL, Wallat JD, Pokorski JK, von Recum HA.
PMID: 28441360
Antibiotics (Basel). 2017 Apr 25;6(2). doi: 10.3390/antibiotics6020011.

The antibiotic erythromycin has limited efficacy and bioavailability due to its instability and conversion under acidic conditions via an intramolecular dehydration reaction. To improve the stability of erythromycin, several analogs have been developed-such as azithromycin and clarithromycin-which decrease the...

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Cyphert EL, Wallat JD, Pokorski JK, et al. Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery. Antibiotics (Basel). 2017;6(2)doi: 10.3390/antibiotics6020011.
Cyphert, E. L., Wallat, J. D., Pokorski, J. K., & von Recum, H. A. (2017). Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery. Antibiotics (Basel, Switzerland), 6(2), . https://doi.org/10.3390/antibiotics6020011
Cyphert, Erika L, et al. "Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery." Antibiotics (Basel, Switzerland) vol. 6,2 (2017). doi: https://doi.org/10.3390/antibiotics6020011
Cyphert EL, Wallat JD, Pokorski JK, von Recum HA. Erythromycin Modification That Improves Its Acidic Stability while Optimizing It for Local Drug Delivery. Antibiotics (Basel). 2017 Apr 25;6(2). doi: 10.3390/antibiotics6020011. PMID: 28441360; PMCID: PMC5485444.
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Showing 1 to 12 of 15 entries