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Showing 1 to 12 of 16 entries
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ADHD and depression: investigating a causal explanation.

Psychological medicine

Riglin L, Leppert B, Dardani C, Thapar AK, Rice F, O'Donovan MC, Davey Smith G, Stergiakouli E, Tilling K, Thapar A.
PMID: 32249726
Psychol Med. 2021 Aug;51(11):1890-1897. doi: 10.1017/S0033291720000665. Epub 2020 Apr 06.

BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is associated with later depression and there is considerable genetic overlap between them. This study investigated if ADHD and ADHD genetic liability are causally related to depression using two different methods.METHODS: First, a longitudinal...

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Riglin L, Leppert B, Dardani C, et al. ADHD and depression: investigating a causal explanation. Psychol Med. 2020;51(11):1890-1897doi: 10.1017/S0033291720000665.
Riglin, L., Leppert, B., Dardani, C., Thapar, A. K., Rice, F., O'Donovan, M. C., Davey Smith, G., Stergiakouli, E., Tilling, K., & Thapar, A. (2021). ADHD and depression: investigating a causal explanation. Psychological medicine, 51(11), 1890-1897. https://doi.org/10.1017/S0033291720000665
Riglin, Lucy, et al. "ADHD and depression: investigating a causal explanation." Psychological medicine vol. 51,11 (2021): 1890-1897. doi: https://doi.org/10.1017/S0033291720000665
Riglin L, Leppert B, Dardani C, Thapar AK, Rice F, O'Donovan MC, Davey Smith G, Stergiakouli E, Tilling K, Thapar A. ADHD and depression: investigating a causal explanation. Psychol Med. 2021 Aug;51(11):1890-1897. doi: 10.1017/S0033291720000665. Epub 2020 Apr 06. PMID: 32249726; PMCID: PMC8381237.
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A robust mean and variance test with application to high-dimensional phenotypes.

European journal of epidemiology

Staley JR, Windmeijer F, Suderman M, Lyon MS, Davey Smith G, Tilling K.
PMID: 34651232
Eur J Epidemiol. 2021 Oct 15; doi: 10.1007/s10654-021-00805-w. Epub 2021 Oct 15.

Most studies of continuous health-related outcomes examine differences in mean levels (location) of the outcome by exposure. However, identifying effects on the variability (scale) of an outcome, and combining tests of mean and variability (location-and-scale), could provide additional insights...

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Staley JR, Windmeijer F, Suderman M, et al. A robust mean and variance test with application to high-dimensional phenotypes. Eur J Epidemiol. 2021;doi: 10.1007/s10654-021-00805-w.
Staley, J. R., Windmeijer, F., Suderman, M., Lyon, M. S., Davey Smith, G., & Tilling, K. (2021). A robust mean and variance test with application to high-dimensional phenotypes. European journal of epidemiology, . https://doi.org/10.1007/s10654-021-00805-w
Staley, James R, et al. "A robust mean and variance test with application to high-dimensional phenotypes." European journal of epidemiology vol. (2021). doi: https://doi.org/10.1007/s10654-021-00805-w
Staley JR, Windmeijer F, Suderman M, Lyon MS, Davey Smith G, Tilling K. A robust mean and variance test with application to high-dimensional phenotypes. Eur J Epidemiol. 2021 Oct 15; doi: 10.1007/s10654-021-00805-w. Epub 2021 Oct 15. PMID: 34651232.
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Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men.

Cerebral cortex (New York, N.Y. : 1991)

Liao Z, Patel Y, Khairullah A, Parker N, Paus T.
PMID: 33429422
Cereb Cortex. 2021 May 10;31(6):2812-2821. doi: 10.1093/cercor/bhaa389.

Adolescence is a period of brain maturation that may involve a second wave of organizational effects of sex steroids on the brain. Rodent studies suggest that, overall, organizational effects of gonadal steroid hormones decrease from the prenatal/perinatal period to...

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Liao Z, Patel Y, Khairullah A, et al. Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men. Cereb Cortex. 2021;31(6):2812-2821doi: 10.1093/cercor/bhaa389.
Liao, Z., Patel, Y., Khairullah, A., Parker, N., & Paus, T. (2021). Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men. Cerebral cortex (New York, N.Y. : 1991), 31(6), 2812-2821. https://doi.org/10.1093/cercor/bhaa389
Liao, Zhijie, et al. "Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men." Cerebral cortex (New York, N.Y. : 1991) vol. 31,6 (2021): 2812-2821. doi: https://doi.org/10.1093/cercor/bhaa389
Liao Z, Patel Y, Khairullah A, Parker N, Paus T. Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men. Cereb Cortex. 2021 May 10;31(6):2812-2821. doi: 10.1093/cercor/bhaa389. PMID: 33429422; PMCID: PMC8107791.
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Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men.

Cerebral cortex (New York, N.Y. : 1991)

Liao Z, Patel Y, Khairullah A, Parker N, Paus T.
PMID: 33429422
Cereb Cortex. 2021 May 10;31(6):2812-2821. doi: 10.1093/cercor/bhaa389.

Adolescence is a period of brain maturation that may involve a second wave of organizational effects of sex steroids on the brain. Rodent studies suggest that, overall, organizational effects of gonadal steroid hormones decrease from the prenatal/perinatal period to...

Cite
Liao Z, Patel Y, Khairullah A, et al. Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men. Cereb Cortex. 2021;31(6):2812-2821doi: 10.1093/cercor/bhaa389.
Liao, Z., Patel, Y., Khairullah, A., Parker, N., & Paus, T. (2021). Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men. Cerebral cortex (New York, N.Y. : 1991), 31(6), 2812-2821. https://doi.org/10.1093/cercor/bhaa389
Liao, Zhijie, et al. "Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men." Cerebral cortex (New York, N.Y. : 1991) vol. 31,6 (2021): 2812-2821. doi: https://doi.org/10.1093/cercor/bhaa389
Liao Z, Patel Y, Khairullah A, Parker N, Paus T. Pubertal Testosterone and the Structure of the Cerebral Cortex in Young Men. Cereb Cortex. 2021 May 10;31(6):2812-2821. doi: 10.1093/cercor/bhaa389. PMID: 33429422; PMCID: PMC8107791.
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Abuse in Childhood and Cardiometabolic Health in Early Adulthood: Evidence From the Avon Longitudinal Study of Parents and Children.

Journal of the American Heart Association

Goncalves Soares A, Zimmerman A, Zammit S, Karl A, Halligan SL, Fraser A.
PMID: 34873916
J Am Heart Assoc. 2021 Dec 21;10(24):e021701. doi: 10.1161/JAHA.121.021701. Epub 2021 Dec 07.

Background Although childhood abuse has been consistently associated with cardiovascular disease in later adulthood, its associations with cardiometabolic health in younger adults are poorly understood. We assessed associations between childhood physical, sexual, and psychological abuse and cardiometabolic outcomes at...

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Goncalves Soares A, Zimmerman A, Zammit S, et al. Abuse in Childhood and Cardiometabolic Health in Early Adulthood: Evidence From the Avon Longitudinal Study of Parents and Children. J Am Heart Assoc. 2021;10(24):e021701doi: 10.1161/JAHA.121.021701.
Goncalves Soares, A., Zimmerman, A., Zammit, S., Karl, A., Halligan, S. L., & Fraser, A. (2021). Abuse in Childhood and Cardiometabolic Health in Early Adulthood: Evidence From the Avon Longitudinal Study of Parents and Children. Journal of the American Heart Association, 10(24), e021701. https://doi.org/10.1161/JAHA.121.021701
Goncalves Soares, Ana, et al. "Abuse in Childhood and Cardiometabolic Health in Early Adulthood: Evidence From the Avon Longitudinal Study of Parents and Children." Journal of the American Heart Association vol. 10,24 (2021): e021701. doi: https://doi.org/10.1161/JAHA.121.021701
Goncalves Soares A, Zimmerman A, Zammit S, Karl A, Halligan SL, Fraser A. Abuse in Childhood and Cardiometabolic Health in Early Adulthood: Evidence From the Avon Longitudinal Study of Parents and Children. J Am Heart Assoc. 2021 Dec 21;10(24):e021701. doi: 10.1161/JAHA.121.021701. Epub 2021 Dec 07. PMID: 34873916.
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THREE AUTHORS REPLY.

American journal of epidemiology

De Stavola BL, Denholm R, Dos-Santos-Silva I.
PMID: 29796653
Am J Epidemiol. 2018 Sep 01;187(9):2070-2071. doi: 10.1093/aje/kwy109.

No abstract available.

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De Stavola BL, Denholm R, Dos-Santos-Silva I. THREE AUTHORS REPLY. Am J Epidemiol. 2018;187(9):2070-2071doi: 10.1093/aje/kwy109.
De Stavola, B. L., Denholm, R., & Dos-Santos-Silva, I. (2018). THREE AUTHORS REPLY. American journal of epidemiology, 187(9), 2070-2071. https://doi.org/10.1093/aje/kwy109
De Stavola, Bianca L, et al. "THREE AUTHORS REPLY." American journal of epidemiology vol. 187,9 (2018): 2070-2071. doi: https://doi.org/10.1093/aje/kwy109
De Stavola BL, Denholm R, Dos-Santos-Silva I. THREE AUTHORS REPLY. Am J Epidemiol. 2018 Sep 01;187(9):2070-2071. doi: 10.1093/aje/kwy109. PMID: 29796653; PMCID: PMC6118065.
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Similarity and stability of face network across populations and throughout adolescence and adulthood.

NeuroImage

Liao Z, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Poustka L, Hohmann S, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Schumann G, Paus T.
PMID: 34560271
Neuroimage. 2021 Dec 01;244:118587. doi: 10.1016/j.neuroimage.2021.118587. Epub 2021 Sep 21.

The ability to extract cues from faces is fundamental for social animals, including humans. An individual's profile of functional connectivity across a face network can be shaped by common organizing principles, stable individual traits, and time-varying mental states. In...

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Liao Z, Banaschewski T, Bokde ALW, et al. Similarity and stability of face network across populations and throughout adolescence and adulthood. Neuroimage. 2021;244:118587doi: 10.1016/j.neuroimage.2021.118587.
Liao, Z., Banaschewski, T., Bokde, A. L. W., Desrivières, S., Flor, H., Grigis, A., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Martinot, J. L., Martinot, M. P., Artiges, E., Nees, F., Orfanos, D. P., Poustka, L., Hohmann, S., Millenet, S., Fröhner, J. H., Smolka, M. N., Walter, H., Whelan, R., Schumann, G., Paus, T. (2021). Similarity and stability of face network across populations and throughout adolescence and adulthood. NeuroImage, 244118587. https://doi.org/10.1016/j.neuroimage.2021.118587
Liao, Zhijie, et al. "Similarity and stability of face network across populations and throughout adolescence and adulthood." NeuroImage vol. 244 (2021): 118587. doi: https://doi.org/10.1016/j.neuroimage.2021.118587
Liao Z, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Poustka L, Hohmann S, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Schumann G, Paus T. Similarity and stability of face network across populations and throughout adolescence and adulthood. Neuroimage. 2021 Dec 01;244:118587. doi: 10.1016/j.neuroimage.2021.118587. Epub 2021 Sep 21. PMID: 34560271.
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Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood.

Clinical epigenetics

Sunny SK, Zhang H, Mzayek F, Relton CL, Ring S, Henderson AJ, Ewart S, Holloway JW, Arshad SH.
PMID: 33407823
Clin Epigenetics. 2021 Jan 06;13(1):5. doi: 10.1186/s13148-020-00992-5.

BACKGROUND: The pattern of lung function development from pre-adolescence to adulthood plays a significant role in the pathogenesis of respiratory diseases. Inconsistent findings in genetic studies on lung function trajectories, the importance of DNA methylation (DNA-M), and the critical...

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Sunny SK, Zhang H, Mzayek F, et al. Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood. Clin Epigenetics. 2021;13(1):5doi: 10.1186/s13148-020-00992-5.
Sunny, S. K., Zhang, H., Mzayek, F., Relton, C. L., Ring, S., Henderson, A. J., Ewart, S., Holloway, J. W., & Arshad, S. H. (2021). Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood. Clinical epigenetics, 13(1), 5. https://doi.org/10.1186/s13148-020-00992-5
Sunny, Shadia Khan, et al. "Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood." Clinical epigenetics vol. 13,1 (2021): 5. doi: https://doi.org/10.1186/s13148-020-00992-5
Sunny SK, Zhang H, Mzayek F, Relton CL, Ring S, Henderson AJ, Ewart S, Holloway JW, Arshad SH. Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood. Clin Epigenetics. 2021 Jan 06;13(1):5. doi: 10.1186/s13148-020-00992-5. PMID: 33407823; PMCID: PMC7789734.
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Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism.

Diabetes

Li-Gao R, Hughes DA, van Klinken JB, de Mutsert R, Rosendaal FR, Mook-Kanamori DO, Timpson NJ, Willems van Dijk K.
PMID: 34610981
Diabetes. 2021 Dec;70(12):2932-2946. doi: 10.2337/db21-0397. Epub 2021 Oct 05.

Humans spend the greater part of the day in a postprandial state. However, the genetic basis of postprandial blood measures is relatively uncharted territory. We examined the genetics of variation in concentrations of postprandial metabolites (

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Li-Gao R, Hughes DA, van Klinken JB, et al. Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism. Diabetes. 2021;70(12):2932-2946doi: 10.2337/db21-0397.
Li-Gao, R., Hughes, D. A., van Klinken, J. B., de Mutsert, R., Rosendaal, F. R., Mook-Kanamori, D. O., Timpson, N. J., & Willems van Dijk, K. (2021). Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism. Diabetes, 70(12), 2932-2946. https://doi.org/10.2337/db21-0397
Li-Gao, Ruifang, et al. "Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism." Diabetes vol. 70,12 (2021): 2932-2946. doi: https://doi.org/10.2337/db21-0397
Li-Gao R, Hughes DA, van Klinken JB, de Mutsert R, Rosendaal FR, Mook-Kanamori DO, Timpson NJ, Willems van Dijk K. Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism. Diabetes. 2021 Dec;70(12):2932-2946. doi: 10.2337/db21-0397. Epub 2021 Oct 05. PMID: 34610981.
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Association of Parent-Reported Sleep Problems in Early Childhood With Psychotic and Borderline Personality Disorder Symptoms in Adolescence.

JAMA psychiatry

Morales-Muñoz I, Broome MR, Marwaha S.
PMID: 32609357
JAMA Psychiatry. 2020 Dec 01;77(12):1256-1265. doi: 10.1001/jamapsychiatry.2020.1875.

IMPORTANCE: Persistent nightmares in childhood have been prospectively associated with psychosis and borderline personality disorder (BPD) in adolescence. However, the extent to which this association is also true for behavioral sleep problems is still unknown, and the potential mechanisms...

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Morales-Muñoz I, Broome MR, Marwaha S. Association of Parent-Reported Sleep Problems in Early Childhood With Psychotic and Borderline Personality Disorder Symptoms in Adolescence. JAMA Psychiatry. 2020;77(12):1256-1265doi: 10.1001/jamapsychiatry.2020.1875.
Morales-Muñoz, I., Broome, M. R., & Marwaha, S. (2020). Association of Parent-Reported Sleep Problems in Early Childhood With Psychotic and Borderline Personality Disorder Symptoms in Adolescence. JAMA psychiatry, 77(12), 1256-1265. https://doi.org/10.1001/jamapsychiatry.2020.1875
Morales-Muñoz, Isabel, et al. "Association of Parent-Reported Sleep Problems in Early Childhood With Psychotic and Borderline Personality Disorder Symptoms in Adolescence." JAMA psychiatry vol. 77,12 (2020): 1256-1265. doi: https://doi.org/10.1001/jamapsychiatry.2020.1875
Morales-Muñoz I, Broome MR, Marwaha S. Association of Parent-Reported Sleep Problems in Early Childhood With Psychotic and Borderline Personality Disorder Symptoms in Adolescence. JAMA Psychiatry. 2020 Dec 01;77(12):1256-1265. doi: 10.1001/jamapsychiatry.2020.1875. PMID: 32609357; PMCID: PMC7330826.
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Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence.

JAMA psychiatry

Mongan D, Föcking M, Healy C, Susai SR, Heurich M, Wynne K, Nelson B, McGorry PD, Amminger GP, Nordentoft M, Krebs MO, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Borgwardt S, Ruhrmann S, Sachs G, Pantelis C, van der Gaag M, de Haan L, Valmaggia L, Pollak TA, Kempton MJ, Rutten BPF, Whelan R, Cannon M, Zammit S, Cagney G, Cotter DR, McGuire P.
PMID: 32857162
JAMA Psychiatry. 2021 Jan 01;78(1):77-90. doi: 10.1001/jamapsychiatry.2020.2459.

IMPORTANCE: Biomarkers that are predictive of outcomes in individuals at risk of psychosis would facilitate individualized prognosis and stratification strategies.OBJECTIVE: To investigate whether proteomic biomarkers may aid prediction of transition to psychotic disorder in the clinical high-risk (CHR) state...

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Mongan D, Föcking M, Healy C, et al. Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence. JAMA Psychiatry. 2021;78(1):77-90doi: 10.1001/jamapsychiatry.2020.2459.
Mongan, D., Föcking, M., Healy, C., Susai, S. R., Heurich, M., Wynne, K., Nelson, B., McGorry, P. D., Amminger, G. P., Nordentoft, M., Krebs, M. O., Riecher-Rössler, A., Bressan, R. A., Barrantes-Vidal, N., Borgwardt, S., Ruhrmann, S., Sachs, G., Pantelis, C., van der Gaag, M., de Haan, L., Valmaggia, L., Pollak, T. A., Kempton, M. J., Rutten, B. P. F., Whelan, R., Cannon, M., Zammit, S., Cagney, G., Cotter, D. R., McGuire, P. (2021). Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence. JAMA psychiatry, 78(1), 77-90. https://doi.org/10.1001/jamapsychiatry.2020.2459
Mongan, David, et al. "Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence." JAMA psychiatry vol. 78,1 (2021): 77-90. doi: https://doi.org/10.1001/jamapsychiatry.2020.2459
Mongan D, Föcking M, Healy C, Susai SR, Heurich M, Wynne K, Nelson B, McGorry PD, Amminger GP, Nordentoft M, Krebs MO, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Borgwardt S, Ruhrmann S, Sachs G, Pantelis C, van der Gaag M, de Haan L, Valmaggia L, Pollak TA, Kempton MJ, Rutten BPF, Whelan R, Cannon M, Zammit S, Cagney G, Cotter DR, McGuire P. Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence. JAMA Psychiatry. 2021 Jan 01;78(1):77-90. doi: 10.1001/jamapsychiatry.2020.2459. PMID: 32857162; PMCID: PMC7450406.
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Genetic overlap and causal associations between smoking behaviours and mental health.

Scientific reports

Barkhuizen W, Dudbridge F, Ronald A.
PMID: 34290290
Sci Rep. 2021 Jul 21;11(1):14871. doi: 10.1038/s41598-021-93962-7.

Cigarette smoking is a modifiable behaviour associated with mental health. We investigated the degree of genetic overlap between smoking behaviours and psychiatric traits and disorders, and whether genetic associations exist beyond genetic influences shared with confounding variables (cannabis and...

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Barkhuizen W, Dudbridge F, Ronald A. Genetic overlap and causal associations between smoking behaviours and mental health. Sci Rep. 2021;11(1):14871doi: 10.1038/s41598-021-93962-7.
Barkhuizen, W., Dudbridge, F., & Ronald, A. (2021). Genetic overlap and causal associations between smoking behaviours and mental health. Scientific reports, 11(1), 14871. https://doi.org/10.1038/s41598-021-93962-7
Barkhuizen, Wikus, et al. "Genetic overlap and causal associations between smoking behaviours and mental health." Scientific reports vol. 11,1 (2021): 14871. doi: https://doi.org/10.1038/s41598-021-93962-7
Barkhuizen W, Dudbridge F, Ronald A. Genetic overlap and causal associations between smoking behaviours and mental health. Sci Rep. 2021 Jul 21;11(1):14871. doi: 10.1038/s41598-021-93962-7. PMID: 34290290; PMCID: PMC8295327.
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