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Showing 1 to 7 of 7 entries
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Purine enzyme inhibition fails to alter benzodiazepine receptor binding in brain.

Neurochemistry international

Gundlach AL, Johnston GA.
PMID: 20501262
Neurochem Int. 1988;12(4):533-7. doi: 10.1016/0197-0186(88)90039-3.

Binding of [(3)H]flunitrazepam to benzodiazepine receptors in brain from several species, including human, was measured in vitro in the presence and absence of purine-metabolizing enzyme inhibitors. Incubation with potent inhibitors of either adenosine deaminase (2?-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl)-adenine) or guanine...

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Gundlach AL, Johnston GA. Purine enzyme inhibition fails to alter benzodiazepine receptor binding in brain. Neurochem Int. 1988;12(4):533-7doi: 10.1016/0197-0186(88)90039-3.
Gundlach, A. L., & Johnston, G. A. (1988). Purine enzyme inhibition fails to alter benzodiazepine receptor binding in brain. Neurochemistry international, 12(4), 533-7. https://doi.org/10.1016/0197-0186(88)90039-3
Gundlach, A L, and Johnston, G A. "Purine enzyme inhibition fails to alter benzodiazepine receptor binding in brain." Neurochemistry international vol. 12,4 (1988): 533-7. doi: https://doi.org/10.1016/0197-0186(88)90039-3
Gundlach AL, Johnston GA. Purine enzyme inhibition fails to alter benzodiazepine receptor binding in brain. Neurochem Int. 1988;12(4):533-7. doi: 10.1016/0197-0186(88)90039-3. PMID: 20501262.
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Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism.

Pharmacology research & perspectives

Nguyen MD, Ross AE, Ryals M, Lee ST, Venton BJ.
PMID: 27022463
Pharmacol Res Perspect. 2015 Nov 16;3(6):e00189. doi: 10.1002/prp2.189. eCollection 2015 Dec.

Adenosine is a neuromodulator that regulates neurotransmission in the brain and central nervous system. Recently, spontaneous adenosine release that is cleared in 3-4 sec was discovered in mouse spinal cord slices and anesthetized rat brains. Here, we examined the...

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Nguyen MD, Ross AE, Ryals M, et al. Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism. Pharmacol Res Perspect. 2015;3(6):e00189doi: 10.1002/prp2.189.
Nguyen, M. D., Ross, A. E., Ryals, M., Lee, S. T., & Venton, B. J. (2015). Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism. Pharmacology research & perspectives, 3(6), e00189. https://doi.org/10.1002/prp2.189
Nguyen, Michael D, et al. "Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism." Pharmacology research & perspectives vol. 3,6 (2015): e00189. doi: https://doi.org/10.1002/prp2.189
Nguyen MD, Ross AE, Ryals M, Lee ST, Venton BJ. Clearance of rapid adenosine release is regulated by nucleoside transporters and metabolism. Pharmacol Res Perspect. 2015 Nov 16;3(6):e00189. doi: 10.1002/prp2.189. eCollection 2015 Dec. PMID: 27022463; PMCID: PMC4777247.
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Chemotherapy and trace element levels in blood and tissue of rats implanted with prostate tumor cells.

Biological trace element research

Kuehn K, Dunzendorfer U, Whitmore WF, Schrauzer GN.
PMID: 24258014
Biol Trace Elem Res. 1985 Dec;8(4):237-50. doi: 10.1007/BF02989579.

Male Copenhagen rats with transplanted prostatic adeno-carcinoma were treated with different polyamine synthesis inhibitors, such as methylglyoxal-bis-guanylhydrazone (MGBG), erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) combined with 9-β-D-arabin-ofuranosyl-adenine (ARA-A), α-difluoromethyl-ornithine (DFMO), and some of their combinations. Levels of the essential trace elements-copper, zinc,...

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Kuehn K, Dunzendorfer U, Whitmore WF, et al. Chemotherapy and trace element levels in blood and tissue of rats implanted with prostate tumor cells. Biol Trace Elem Res. 1985;8(4):237-50doi: 10.1007/BF02989579.
Kuehn, K., Dunzendorfer, U., Whitmore, W. F., & Schrauzer, G. N. (1985). Chemotherapy and trace element levels in blood and tissue of rats implanted with prostate tumor cells. Biological trace element research, 8(4), 237-50. https://doi.org/10.1007/BF02989579
Kuehn, K, et al. "Chemotherapy and trace element levels in blood and tissue of rats implanted with prostate tumor cells." Biological trace element research vol. 8,4 (1985): 237-50. doi: https://doi.org/10.1007/BF02989579
Kuehn K, Dunzendorfer U, Whitmore WF, Schrauzer GN. Chemotherapy and trace element levels in blood and tissue of rats implanted with prostate tumor cells. Biol Trace Elem Res. 1985 Dec;8(4):237-50. doi: 10.1007/BF02989579. PMID: 24258014.
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A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences

Bazl R, Ganjali MR, Saboury AA, Foroumadi A, Nourozi P, Amanlou M.
PMID: 23351306
Daru. 2012 Oct 22;20(1):64. doi: 10.1186/2008-2231-20-64.

BACKGROUND AND THE PURPOSE OF THE STUDY: Adenosine deaminase (ADA) inhibition not only may be applied for the treatment of ischemic injury, hypertension, lymphomas and leukaemia, but also they have been considered as anti- inflammatory drugs. On the other...

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Bazl R, Ganjali MR, Saboury AA, et al. A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study. Daru. 2012;20(1):64doi: 10.1186/2008-2231-20-64.
Bazl, R., Ganjali, M. R., Saboury, A. A., Foroumadi, A., Nourozi, P., & Amanlou, M. (2012). A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 20(1), 64. https://doi.org/10.1186/2008-2231-20-64
Bazl, Roya, et al. "A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study." Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences vol. 20,1 (2012): 64. doi: https://doi.org/10.1186/2008-2231-20-64
Bazl R, Ganjali MR, Saboury AA, Foroumadi A, Nourozi P, Amanlou M. A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study. Daru. 2012 Oct 22;20(1):64. doi: 10.1186/2008-2231-20-64. PMID: 23351306; PMCID: PMC3556010.
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Stimulation-evoked release of purines from the rabbit retina.

Neurochemistry international

Perez MT, Arnér K, Ehinger B.
PMID: 19651086
Neurochem Int. 1988;13(3):307-18. doi: 10.1016/0197-0186(88)90003-4.

The evoked release of purines from rabbit retinae preloaded with [(3)H]adenosine was studied in vitro. Potassium (8.6-43.6 mM) and ouabain (1 or 10 microM) increased the release of radioactivity in a concentration-dependent manner. The K(+)-evoked release was significantly reduced...

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Perez MT, Arnér K, Ehinger B. Stimulation-evoked release of purines from the rabbit retina. Neurochem Int. 1988;13(3):307-18doi: 10.1016/0197-0186(88)90003-4.
Perez, M. T., Arnér, K., & Ehinger, B. (1988). Stimulation-evoked release of purines from the rabbit retina. Neurochemistry international, 13(3), 307-18. https://doi.org/10.1016/0197-0186(88)90003-4
Perez, M T, et al. "Stimulation-evoked release of purines from the rabbit retina." Neurochemistry international vol. 13,3 (1988): 307-18. doi: https://doi.org/10.1016/0197-0186(88)90003-4
Perez MT, Arnér K, Ehinger B. Stimulation-evoked release of purines from the rabbit retina. Neurochem Int. 1988;13(3):307-18. doi: 10.1016/0197-0186(88)90003-4. PMID: 19651086.
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Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects.

Frontiers in physiology

Fedan JS, Thompson JA, Ismailoglu UB, Jing Y.
PMID: 24130533
Front Physiol. 2013 Oct 11;4:287. doi: 10.3389/fphys.2013.00287. eCollection 2013.

In asthmatic patients, inhalation of hyperosmolar saline or D-mannitol (D-M) elicits bronchoconstriction, but in healthy subjects exercise causes bronchodilation. Hyperventilation causes drying of airway surface liquid (ASL) and increases its osmolarity. Hyperosmolar challenge of airway epithelium releases epithelium-derived relaxing...

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Fedan JS, Thompson JA, Ismailoglu UB, et al. Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects. Front Physiol. 2013;4:287doi: 10.3389/fphys.2013.00287.
Fedan, J. S., Thompson, J. A., Ismailoglu, U. B., & Jing, Y. (2013). Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects. Frontiers in physiology, 4287. https://doi.org/10.3389/fphys.2013.00287
Fedan, Jeffrey S, et al. "Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects." Frontiers in physiology vol. 4 (2013): 287. doi: https://doi.org/10.3389/fphys.2013.00287
Fedan JS, Thompson JA, Ismailoglu UB, Jing Y. Tracheal epithelium cell volume responses to hyperosmolar, isosmolar and hypoosmolar solutions: relation to epithelium-derived relaxing factor (EpDRF) effects. Front Physiol. 2013 Oct 11;4:287. doi: 10.3389/fphys.2013.00287. eCollection 2013. PMID: 24130533; PMCID: PMC3795350.
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Development of dried blood spot quality control materials for adenosine deaminase severe combined immunodeficiency and LC-MS/MS method for their characterization.

Clinical mass spectrometry (Del Mar, Calif.)

Young B, Hendricks J, Foreman D, Pickens CA, Hovell C, De Jesús VR, Haynes C, Petritis K.
PMID: 33851028
Clin Mass Spectrom. 2020 Aug;17(4):4-11. doi: 10.1016/j.clinms.2020.07.002. Epub 2020 Jul 10.

Adenosine deaminase severe combined immunodeficiency (ADA-SCID) is an autosomal recessive disorder in which a lack of ADA enzyme prevents the maturation of T- and B-cells; early intervention is crucial for restoring immune function in affected neonates. ADA is responsible...

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Young B, Hendricks J, Foreman D, et al. Development of dried blood spot quality control materials for adenosine deaminase severe combined immunodeficiency and LC-MS/MS method for their characterization. Clin Mass Spectrom. 2020;17(4):4-11doi: 10.1016/j.clinms.2020.07.002.
Young, B., Hendricks, J., Foreman, D., Pickens, C. A., Hovell, C., De Jesús, V. R., Haynes, C., & Petritis, K. (2020). Development of dried blood spot quality control materials for adenosine deaminase severe combined immunodeficiency and LC-MS/MS method for their characterization. Clinical mass spectrometry (Del Mar, Calif.), 17(4), 4-11. https://doi.org/10.1016/j.clinms.2020.07.002
Young, Brian, et al. "Development of dried blood spot quality control materials for adenosine deaminase severe combined immunodeficiency and LC-MS/MS method for their characterization." Clinical mass spectrometry (Del Mar, Calif.) vol. 17,4 (2020): 4-11. doi: https://doi.org/10.1016/j.clinms.2020.07.002
Young B, Hendricks J, Foreman D, Pickens CA, Hovell C, De Jesús VR, Haynes C, Petritis K. Development of dried blood spot quality control materials for adenosine deaminase severe combined immunodeficiency and LC-MS/MS method for their characterization. Clin Mass Spectrom. 2020 Aug;17(4):4-11. doi: 10.1016/j.clinms.2020.07.002. Epub 2020 Jul 10. PMID: 33851028; PMCID: PMC8040805.
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Showing 1 to 7 of 7 entries