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Structure-based function analysis of putative conserved proteins with isomerase activity from Haemophilus influenzae.

3 Biotech

Shahbaaz M, Ahmad F, Hassan MI.
PMID: 28324524
3 Biotech. 2015 Oct;5(5):741-763. doi: 10.1007/s13205-014-0274-1. Epub 2014 Dec 28.

Haemophilus influenzae, a Gram-negative bacterium and a member of the family Pasteurellaceae, causes chronic bronchitis, bacteremia, meningitis, etc. The H. influenzae is the first organism whose genome was completely sequenced and annotated. Here, we have extensively analyzed the genome...

Exploring targeted therapy of osteosarcoma using proteomics data.

OncoTargets and therapy

Chaiyawat P, Settakorn J, Sangsin A, Teeyakasem P, Klangjorhor J, Soongkhaw A, Pruksakorn D.
PMID: 28203090
Onco Targets Ther. 2017 Feb 01;10:565-577. doi: 10.2147/OTT.S119993. eCollection 2017.

Despite multimodal therapeutic treatments of osteosarcoma (OS), some patients develop resistance to currently available regimens and eventually end up with recurrent or metastatic outcomes. Many attempts have been made to discover effective drugs for improving outcome; however, due to...

Identification of cancer mechanisms through computational systems modeling.

Translational cancer research

Qi Z, Voit EO.
PMID: 26662197
Transl Cancer Res. 2014 Jun 01;3(3):233-242. doi: 10.3978/j.issn.2218-676X.2014.05.03.

BACKGROUND: Colorectal cancer is one of the most prevalent causes of cancer death. It has been studied extensively for a long time, and numerous genetic and epigenetic events have been associated with the disease. However, its molecular mechanisms are...

Showing 1 to 3 of 3 entries