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Showing 1 to 12 of 23 entries
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Mating preference inSchistosoma mansoni.

Journal of chemical ecology

Shirazian D, Childs JE, Hawkins JT, Schiller EL.
PMID: 24305888
J Chem Ecol. 1986 Aug;12(8):1713-23. doi: 10.1007/BF01022376.

We investigated the suitability of an in vitro culture system for measurement of mating behavior ofSchistosoma mansoni. The criteria used to evaluate this system were the level of phosphorylated nucleotides, egg production, and mating status of parasites. The level...

Molecular Action and Clinical Relevance of Aromatase Inhibitors.

The oncologist

Murphy MJ.
PMID: 10388095
Oncologist. 1998;3(2):129-130.

BREAST CANCER: HIGH PREVALENCE AND RISING INCIDENCE: Breast cancer is the most common form of cancer among women in Europe, North and South America and Australasia; approximately 1 in 10 women in Western countries will develop breast cancer during...

Polycyclic aromatic hydrocarbons inhibit in vitro ovarian steroidogenesis in the flounder (Platichthys flesus L.).

Aquatic toxicology (Amsterdam, Netherlands)

Rocha Monteiro PR, Reis-Henriques MA, Coimbra J.
PMID: 10794836
Aquat Toxicol. 2000 Apr 01;48(4):549-559. doi: 10.1016/s0166-445x(99)00055-7.

The in vitro effect of polycyclic aromatic hydrocarbons (PAHs) on ovarian steroidogenesis of the flounder (Platichthys flesus L.) was determined. Fully vitellogenic ovary tissue was in vitro incubated in the presence of phenanthrene, benzo[a]pyrene or chrysene, using 17alpha-hydroxyprogesterone or...

Effects of aminoglutethimide phosphate on litter size and birth weight in superovulated rats.

Theriogenology

Ishibashi I, Abe M, Ikeda I, Watanabe T.
PMID: 16727124
Theriogenology. 1992 Jul;38(1):127-36. doi: 10.1016/0093-691x(92)90224-f.

In this study, litter sizes, birth weights and survival rates of neonates in superovulated rats treated with aminoglutethimide phosphate (AGP) were studied. Young (8- to 9-week old) and adult (14- to 16-week old) rats were treated with 20 or...

Aminoglutethimide-induced leucopenia in a mouse model: effects of metabolic and structural determinates.

Environmental toxicology and pharmacology

Coleman MD, Khalaf LF, Nicholls PJ.
PMID: 21782676
Environ Toxicol Pharmacol. 2003 Dec;15(1):27-32. doi: 10.1016/j.etap.2003.08.003.

A model of human leucopenia has been developed further in the female mouse. Following daily administration to female mice of 50 mg/kg of the aromatase inhibitor aminoglutethimide, significant falls in platelet and white cell counts occurred after 2 and...

Tamsulosin facilitates depressive-like behaviors in mice: Involvement of endogenous glucocorticoids.

Brain research bulletin

Holanda VAD, Oliveira MC, da Silva Junior ED, Gavioli EC.
PMID: 34798218
Brain Res Bull. 2022 Jan;178:29-36. doi: 10.1016/j.brainresbull.2021.11.005. Epub 2021 Nov 17.

The benign prostatic hyperplasia (BPH) is the main source of lower urinary tract symptoms. The BPH is a common age-dependent disease and tamsulosin is an α

Androgen receptor signaling inhibitors: post-chemotherapy, pre-chemotherapy and now in castration-sensitive prostate cancer.

Endocrine-related cancer

Mitsiades N, Kaochar S.
PMID: 34128827
Endocr Relat Cancer. 2021 Jul 15;28(8):T19-T38. doi: 10.1530/ERC-21-0098.

Based on pioneering work by Huggins, Hodges and others, hormonal therapies have been established as an effective approach for advanced prostate cancer (PC) for the past eight decades. However, it quickly became evident that androgen deprivation therapy (ADT) via...

Molecular docking and dynamics simulation to screen interactive potency and stability of fungicide tebuconazole with thyroid and sex hormone-binding globulin: Implications of endocrine and reproductive interruptions.

Journal of applied toxicology : JAT

Abdi SAH, Alzahrani A, Asad M, Alquraini A, Alghamdi AI, Sayed SF.
PMID: 33629778
J Appl Toxicol. 2021 Oct;41(10):1649-1659. doi: 10.1002/jat.4153. Epub 2021 Feb 25.

Tebuconazole is a widely used fungicide in agriculture, and it may easily enter in the human food chain. In addition, tebuconzaol skin permeation coefficient (Log Kp) is -5.55 cm/s and it does not violate Lipinski's rule. It may mimic...

Effects of aminoglutethimide phosphate administration on the incidence of pregnancy and number of live fetuses in superovulated rats.

Theriogenology

Ishibashi I, Fujimoto G, Hishii T.
PMID: 16727039
Theriogenology. 1991 Oct;36(4):699-708. doi: 10.1016/0093-691x(91)90407-5.

This study examined the effects of aminoglutethimide phosphate (AGP) administration on the incidence of pregnancy and number of live fetuses in superovulated rats. Immature (31- to 33-day-old) young (8- to 9-week-old) and (14- to 16-week-old) rats were treated with...

Complexes With Biologically Active Ligands. Part 2. Preparation of Copper(II) Complexes of Positively-Charged Derivatives of Aminoglutethimide.

Metal-based drugs

Supuran CT.
PMID: 18472796
Met Based Drugs. 1996;3(2):57-62. doi: 10.1155/MBD.1996.57.

Cu(II) complexes of 1-[4-(3-ethyl-piperidine-2,6-dione)-3-yl]-phenyl-2,4,6-trisubstituted pyridinium perchlorates, containing alkyl, aryl and combinations of these two types of moieties in their molecule were synthesized and characterized by elemental analysis, spectroscopy, magnetic, thermogravimetric and conductimetric measurements. In these complexes, Cu(II) ions are...

Aminoglutethimide in the treatment of congenital adrenal hyperplasia.

Archives of disease in childhood

Hamilton W.
PMID: 21032503
Arch Dis Child. 1973 Oct;48(10):828. doi: 10.1136/adc.48.10.828-b.

No abstract available.

Management Strategies for Aggressive Cushing's Syndrome: From Macroadenomas to Ectopics.

Journal of oncology

Pozza C, Graziadio C, Giannetta E, Lenzi A, Isidori AM.
PMID: 22934113
J Oncol. 2012;2012:685213. doi: 10.1155/2012/685213. Epub 2012 Aug 09.

Cushing's syndrome (CS) is a rare but severe clinical condition represented by an excessive endogenous cortisol secretion and hence excess circulating free cortisol, characterized by loss of the normal feedback regulation and circadian rhythm of the hypothalamic-pituitary axis due...

Showing 1 to 12 of 23 entries