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Showing 1 to 6 of 6 entries
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The immune system in irritable bowel syndrome.

Journal of neurogastroenterology and motility

Barbara G, Cremon C, Carini G, Bellacosa L, Zecchi L, De Giorgio R, Corinaldesi R, Stanghellini V.
PMID: 22148103
J Neurogastroenterol Motil. 2011 Oct;17(4):349-59. doi: 10.5056/jnm.2011.17.4.349. Epub 2011 Oct 31.

The potential relevance of systemic and gastrointestinal immune activation in the pathophysiology and symptom generation in the irritable bowel syndrome (IBS) is supported by a number of observations. Infectious gastroenteritis is the strongest risk factor for the development of...

Implication of cytokines: Roles of tumor necrosis factor-alpha in liver injury.

Hepatology research : the official journal of the Japan Society of Hepatology

Nagaki M, Moriwaki H.
PMID: 19125946
Hepatol Res. 2008 Nov;38:S19-28. doi: 10.1111/j.1872-034X.2008.00422.x.

Acute liver failure caused by viruses, drugs, or liver resection, is marked by a massive degree of hepatocyte apoptosis and impaired hepatocyte proliferation, the mechanisms of which, however, still remain to be understood. The choice between life and death...

[Not Available].

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Sabbaj S, Kiyono H, McGhee JR.
PMID: 18031087
BioDrugs. 1997 Feb;7(2):134-57. doi: 10.2165/00063030-199707020-00006.

Oral delivery of vaccines results in these being taken up by specialised microfold epithelial cells covering Peyer's patches of the gastrointestinal tract, therefore stimulating regulatory T cells and surface IgA positive (sIgA+) B cells. T helper cells can be...

Detection of impaired IgG antibody formation facilitates the decision on early immunoglobulin replacement in hypogammaglobulinemic patients.

Frontiers in immunology

Wolf HM, Thon V, Litzman J, Eibl MM.
PMID: 25699049
Front Immunol. 2015 Feb 02;6:32. doi: 10.3389/fimmu.2015.00032. eCollection 2015.

Hypogammaglobulinemia (serum IgG lower than 2 SD below the age-matched mean) and clinical symptoms such as increased susceptibility to infection, autoimmune manifestations, granulomatous disease, and unexplained polyclonal lymphoproliferation are considered to be diagnostic hallmarks in patients with common variable...

Epidemiologic Survey of Legionella Urine Antigen Testing Within a Large Wisconsin-Based Health Care System.

Journal of patient-centered research and reviews

Toberna CP, William HM, Kram JJF, Heslin K, Baumgardner DJ.
PMID: 32377550
J Patient Cent Res Rev. 2020 Apr 27;7(2):165-175. doi: 10.17294/2330-0698.1721. eCollection 2020.

PURPOSE: Legionella pneumophila pneumonia is a life-threatening, environmentally acquired infection identifiable via Legionella urine antigen tests (LUAT). We aimed to identify cumulative incidence, demographic distribution, and undetected disease outbreaks of Legionella pneumonia via positive LUAT in a single eastern...

Camelid Single-Domain Antibodies for the Development of Potent Diagnosis Platforms.

Molecular diagnosis & therapy

Brilhante-da-Silva N, de Oliveira Sousa RM, Arruda A, Dos Santos EL, Marinho ACM, Stabeli RG, Fernandes CFC, Pereira SDS.
PMID: 34146333
Mol Diagn Ther. 2021 Jul;25(4):439-456. doi: 10.1007/s40291-021-00533-7. Epub 2021 Jun 19.

The distinct biophysical and pharmaceutical properties of camelid single-domain antibodies, referred to as VHHs or nanobodies, are associated with their nanometric dimensions, elevated stability, and antigen recognition capacity. These biomolecules can circumvent a number of diagnostic system limitations, especially...

Showing 1 to 6 of 6 entries